Cited by 1,059Bacterial biofilms and quorum sensingBacterial Genetics and BiotechnologyEscherichia coli research studies

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Indole as an intercellular signal in microbial communities

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Lee, Jin-Hyung, Lee, Jintae·2010·FEMS Microbiology Reviews

DOI 10.1111/j.1574-6976.2009.00204.x

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Abstract

Bacteria can utilize signal molecules to coordinate their behavior to survive in dynamic multispecies communities. Indole is widespread in the natural environment, as a variety of both Gram-positive and Gram-negative bacteria (to date, 85 species) produce large quantities of indole. Although it has been known for over 100 years that many bacteria produce indole, the real biological roles of this molecule are only now beginning to be unveiled. As an intercellular signal molecule, indole controls diverse aspects of bacterial physiology, such as spore formation, plasmid stability, drug resistance, biofilm formation, and virulence in indole-producing bacteria. In contrast, many non-indole-producing bacteria, plants and animals produce diverse oxygenases which may interfere with indole signaling. It appears indole plays an important role in bacterial physiology, ecological balance, and possibly human health. Here we discuss our current knowledge and perspectives on indole signaling.

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QUORUM SENSING: Cell-to-Cell Communication in Bacteria
Waters, C. M., & Bassler, B. L. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.012704.131001 · Cited by 3,989
Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators
Fuqua, W. C., Winans, S. C., & Greenberg, E. P. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.2.269-275.1994 · Cited by 2,941
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
Wikoff, W. R., Anfora, A. T., Liu, J., Schultz, P. G., Lesley, S. A., Peters, E. C., & Siuzdak, G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812874106 · Cited by 2,677
Commensal Host-Bacterial Relationships in the Gut
Hooper, L. V., & Gordon, J. I. (2001) · Science · doi:10.1126/science.1058709 · Cited by 2,362
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
Hentzer, M., Wu, H., Andersen, J. B., Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., et al. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg366 · Cited by 1,440
Microbes in Gastrointestinal Health and Disease
Neish, A. S. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.10.080 · Cited by 1,423
Identification, Timing, and Signal Specificity of Pseudomonas aeruginosa Quorum-Controlled Genes: a Transcriptome Analysis
Schuster, M., Lostroh, P., Ogi, T., & Greenberg, E. P. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.7.2066-2079.2003 · Cited by 1,127
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound
Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, J. B., Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, N., et al. (2002) · Microbiology · doi:10.1099/00221287-148-1-87 · Cited by 1,053
How bacteria talk to each other: regulation of gene expression by quorum sensing
Bassler, B. L. (1999) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(99)00025-9 · Cited by 1,046
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
Higdon, J. V., Delage, B., WILLIAMS, D., & Dashwood, R. H. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.01.009 · Cited by 1,038

Show all 174 references

Research works printed but not linked: 1

Pittard AJ (1996) Biosynthesis of the aromatic amino acids: the tryptophan pathway. Escherichia coli and Salmonella: Cellular and Molecular Biology ( Neidhardt FC , ed), pp. 458–484. ASM Press, Washington, DC.

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Authors: Lee, J.-H., & Lee, J.
Affiliations: Yeungnam University (KR)
Corresponding author: Lee, Jintae
ORCID: Lee, Jin-Hyung
Lee, Jintae
Venue: FEMS Microbiology Reviews
Publisher: Oxford University Press (OUP)
Published: 2010-07
Volume: 34
Issue: 4
Pages: 426-444
ISSN: 0168-6445 (ISSN-L)
1574-6976
DOI: 10.1111/j.1574-6976.2009.00204.x
OpenAlex: W2049821596
Cited by: 1,059
References: 174
Citations by year: 2026: 82 · 2025: 113 · 2024: 94 · 2023: 115 · 2022: 112 · 2021: 99 · 2020: 89 · 2019: 62 · 2018: 61 · 2017: 42 · 2016: 36 · 2015: 44 · 2014: 42 · 2013: 27 · 2012: 17
FWCI: 1.02
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: FEMS Microbiology Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: Yeungnam University
Directorate for Education and Human Resources
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Life Sciences › Immunology and Microbiology › Microbiology › Escherichia coli research studies
Keywords: intercellular communication, bacterial quorum sensing, microbial communities, sporulation, plasmid stability, drug resistance, biofilm formation, virulence, Gram-positive bacteria, Gram-negative bacteria
MeSH terms: Bacteria, Indoles, Plasmids, Virulence, Signal Transduction, Gene Expression Regulation, Bacterial, Bacterial Physiological Phenomena, Biofilms, Drug Resistance, Bacterial, Quorum Sensing

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