The DOI matches its Crossref record; 289 of the 289 references it cites were found in a registry or an index.
Physical illness and schizophrenia: a review of the literature
Abstract
Objective: The lifespan of people with schizophrenia is shortened compared to the general population. We reviewed the literature on comorbid physical diseases in schizophrenia to provide a basis for initiatives to fight this unacceptable situation. Method: We searched MEDLINE (1966 – May 2006) combining the MeSH term of schizophrenia with the 23 MeSH terms of general physical disease categories to identify relevant epidemiological studies. Results: A total of 44 202 abstracts were screened. People with schizophrenia have higher prevalences of HIV infection and hepatitis, osteoporosis, altered pain sensitivity, sexual dysfunction, obstetric complications, cardiovascular diseases, overweight, diabetes, dental problems, and polydipsia than the general population. Rheumatoid arthritis and cancer may occur less frequently than in the general population. Eighty‐six per cent of the studies came from industrialized countries limiting the generalizability of the findings. Conclusion: The increased frequency of physical diseases in schizophrenia might be on account of factors related to schizophrenia and its treatment, but undoubtedly also results from the unsatisfactory organization of health services, from the attitudes of medical doctors, and the social stigma ascribed to the schizophrenic patients.
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In the citing paper
“They are also less likely to receive appropriate medications, such as b-blockers and statins, on discharge following myocardial infarction.119”
From The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness (2019) · cites this paper as [119]
In the citing paper
“There is an extensive literature reporting an increased occurrence of obstetric complications among women who have schizophrenia (15).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [15]
Citations
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DE HERT, M., CORRELL, C. U., BOBES, J., CETKOVICH‐BAKMAS, M., COHEN, D., ASAI, I., DETRAUX, J., GAUTAM, S., MÖLLER, H., NDETEI, D. M., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00014.x · Cited by 2,488
Self-citationScott, A. J., Webb, T. L., Martyn-St James, M., Rowse, G., & Weich, S. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101556 · Cited by 1,094
Knaak, S., Mantler, E., & Szeto, A. (2017) · Healthcare Management Forum · doi:10.1177/0840470416679413 · Cited by 1,031
De Hert, M., Dekker, J. M., Wood, D., Kahl, K. G., Holt, R. I. G., & Möller, H.-J. (2009) · European Psychiatry · doi:10.1016/j.eurpsy.2009.01.005 · Cited by 951
Correll, C. U., Detraux, J., De Lepeleire, J., & De Hert, M. (2015) · World Psychiatry · doi:10.1002/wps.20204 · Cited by 820
Metadata
- Authors
- Leucht, S., Burkard, T., Henderson, J., Maj, M., & Sartorius, N.
- Affiliations
- TUM Klinikum (DE)
- University of Naples Federico II (IT)
- Corresponding author
- Leucht, S.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2007-10-04
- Volume
- 116
- Issue
- 5
- Pages
- 317-333
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W2158448796
- Cited by
- 633
- References
- 289
- Citations by year
- 2026: 5 · 2025: 14 · 2024: 25 · 2023: 22 · 2022: 24 · 2021: 28 · 2020: 28 · 2019: 42 · 2018: 32 · 2017: 36 · 2016: 47 · 2015: 44 · 2014: 51 · 2013: 49 · 2012: 41
- FWCI
- 4.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- schizophrenia, somatic comorbidity, physical illness, mortality, HIV infection, hepatitis, osteoporosis, pain sensitivity, sexual dysfunction, cardiovascular disease, diabetes mellitus, dental problems, polydipsia, rheumatoid arthritis, cancer, antipsychotic adverse effects, health care organization, stigma
- MeSH terms
- Cause of Death, Cross-Sectional Studies, Health Status Indicators, Humans, Schizophrenia, Comorbidity, Incidence
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