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Cited by 633Schizophrenia research and treatmentMental Health and PsychiatryMental Health Treatment and Access

The DOI matches its Crossref record; 289 of the 289 references it cites were found in a registry or an index.

Physical illness and schizophrenia: a review of the literature

Leucht, S., Burkard, T., Henderson, J., Maj, M., Sartorius, N.·2007·Acta Psychiatrica Scandinavica
DOI 10.1111/j.1600-0447.2007.01095.x
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Abstract

Objective: The lifespan of people with schizophrenia is shortened compared to the general population. We reviewed the literature on comorbid physical diseases in schizophrenia to provide a basis for initiatives to fight this unacceptable situation. Method: We searched MEDLINE (1966 – May 2006) combining the MeSH term of schizophrenia with the 23 MeSH terms of general physical disease categories to identify relevant epidemiological studies. Results: A total of 44 202 abstracts were screened. People with schizophrenia have higher prevalences of HIV infection and hepatitis, osteoporosis, altered pain sensitivity, sexual dysfunction, obstetric complications, cardiovascular diseases, overweight, diabetes, dental problems, and polydipsia than the general population. Rheumatoid arthritis and cancer may occur less frequently than in the general population. Eighty‐six per cent of the studies came from industrialized countries limiting the generalizability of the findings. Conclusion: The increased frequency of physical diseases in schizophrenia might be on account of factors related to schizophrenia and its treatment, but undoubtedly also results from the unsatisfactory organization of health services, from the attitudes of medical doctors, and the social stigma ascribed to the schizophrenic patients.

Overview

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Registry

Crossref · 10.1111/j.1600-0447.2007.01095.x

Cites

289 of 289 references verified0 citation errors · 0 not checkable

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Citations

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Research works printed but not linked: 9

  1. WHO, HIV and AIDS statistics and features, end of 2002 and 2004
  2. Nakane Y, 1986, Psychiatric Case Registers in public health, 240
  3. Dupont A, 1986, Psychiatric Case Registers in public health, 229
  4. 10.1046/j.1440-1614.2000.00737.x · DOI
  5. Templer DI, 1985, Similar distribution of schizophrenia and multiple sclerosis, J Clin Psychiatry, 46, 73
  6. Perkins DO, 2003, Medical illness and schizophrenia, 215
  7. Essen‐Moller W, 1935, Untersuchungen über die Fruchtbarkeit gewisser Gruppen von Geisteskranken, Acta Psychiatr Neurol Suppl, 8, 1
  8. Bellnier TJ, 2003, The prevalence of metabolic disturbances in schizophrenic and bipolar I patients prior to antipsychotic use
  9. Littrell K, 2003, Insulin resistance and syndrome X among schizophrenia patients

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Metadata

Authors
Leucht, S., Burkard, T., Henderson, J., Maj, M., & Sartorius, N.
Affiliations
  • TUM Klinikum (DE)
  • University of Naples Federico II (IT)
Corresponding author
Leucht, S.
ORCID
Venue
Acta Psychiatrica Scandinavica
Publisher
Wiley
Published
2007-10-04
Volume
116
Issue
5
Pages
317-333
ISSN
  • 0001-690X (ISSN-L)
  • 1600-0447
DOI
10.1111/j.1600-0447.2007.01095.x
OpenAlex
W2158448796
Cited by
633
References
289
Citations by year
2026: 5 · 2025: 14 · 2024: 25 · 2023: 22 · 2022: 24 · 2021: 28 · 2020: 28 · 2019: 42 · 2018: 32 · 2017: 36 · 2016: 47 · 2015: 44 · 2014: 51 · 2013: 49 · 2012: 41
FWCI
4.25
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Acta Psychiatrica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
  • mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords
schizophrenia, somatic comorbidity, physical illness, mortality, HIV infection, hepatitis, osteoporosis, pain sensitivity, sexual dysfunction, cardiovascular disease, diabetes mellitus, dental problems, polydipsia, rheumatoid arthritis, cancer, antipsychotic adverse effects, health care organization, stigma
MeSH terms
Cause of Death, Cross-Sectional Studies, Health Status Indicators, Humans, Schizophrenia, Comorbidity, Incidence

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