The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Regulatory T cells and Foxp3
Open accessAbstract
Summary: Regulatory T (Treg) cells play central role in regulation of immune responses to self‐antigens, allergens, and commensal microbiota as well as immune responses to infectious agents and tumors. Transcriptional factor Foxp3 serves as a lineage specification factor of Treg cells. Paucity of Treg cells due to loss‐of‐function mutations of the Foxp3 gene is responsible for highly aggressive, fatal, systemic immune‐mediated inflammatory lesions in mice and humans. Recent studies of Foxp3 expression and function provided critical novel insights into biology of Treg cells and into cellular mechanisms of the immune homeostasis.
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Control of Regulatory T Cell Development by the Transcription Factor Foxp3
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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
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Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3
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TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
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Metadata
- Authors
- Rudensky, A. Y.
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2011-04-13
- Volume
- 241
- Issue
- 1
- Pages
- 260-268
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- OpenAlex
- W1690266756
- Cited by
- 765
- References
- 77
- FWCI
- 2.63
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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