The ectonucleotidases CD 39 and CD 73: Novel checkpoint inhibitor targets

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IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

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The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

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Purinergic Signaling during Inflammation

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Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

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Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

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Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

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Immunological mechanisms of the antitumor effects of supplemental oxygenation

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Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

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Extracellular purines, purinergic receptors and tumor growth

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Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia

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Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production

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The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

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STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

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CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

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CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

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Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs

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Untitled work

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CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression

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Purinergic Control of T Cell Activation by ATP Released Through Pannexin-1 Hemichannels

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CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis

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Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25highFOXP3+ Regulatory T Cells

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Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses

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Tumor Cell Death and ATP Release Prime Dendritic Cells and Efficient Anticancer Immunity

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The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively.

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ATP Release From Activated Neutrophils Occurs via Connexin 43 and Modulates Adenosine-Dependent Endothelial Cell Function

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Blockade of A 2A receptors potently suppresses the metastasis of CD73 + tumors

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