Digital pulse plethysmography (DPG) in studies of the hemodynamic response to nitrates — A survey of recording methods and principles of analysis
Abstract
Abstract:Digital pulse plethysmography (DPG) has proved a technically simple, noninvasive, sensitive and informative technique for studying the effects of nitroglycerin and other nitrates on peripheral arteries. The importance of performing nitrate evaluation by DPG mainly in elderly subjects is emphasized. On the basis of observations with DPG some indirect conclusions on the effect of nitrates on the coronary arteries are justified. — A review, with recommendations based on own experience, is given of various recording techniques and principles of evaluating quantitatively the digital volume pulse contour, with special reference to the influence of nitrates on the position and appearance of dicrotism. DPG seems to be a convenient, noninvasive and helpful procedure in studies on the development of nitrate tolerance.
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The decrease in PAR at rest suggests that a decrease in peripheral vascular tone was caused by nitrate or subsequent metabolites.
“suggesting that a decrease in peripheral vascular tone (Bahra et al. 2012) was caused by nitrate or subsequent metabolites (Lund 1986).”
From Oral nitrate and citrulline decrease blood pressure and increase vascular conductance in young adults: a potential therapy for heart failure (2016) · cites this paper as Lund 1986
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- Authors
- Lund, F.
- Affiliations
- Karolinska University Hospital (SE)
- Corresponding author
- Lund, Fredrik
- Venue
- Acta Pharmacologica et Toxicologica
- Publisher
- Wiley
- Published
- 1986-11
- Volume
- 59
- Issue
- S6
- Pages
- 79-96
- ISSN
- 0001-6683 (ISSN-L)
- OpenAlex
- W1994425225
- Cited by
- 34
- References
- 45
- Citations by year
- 2021: 2 · 2020: 2 · 2018: 1 · 2017: 1 · 2016: 2 · 2014: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Pharmacologica et Toxicologica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Keywords
- nitrate, nitroglycerin, peripheral arteries, nitrate tolerance, coronary arteries, elderly patients, hemodynamic response
- MeSH terms
- Fingers, Hemodynamics, Humans, Nitrates, Plethysmography, Regional Blood Flow
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