The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Aging of human muscle: structure, function and adaptability
Abstract
With increasing age, human skeletal muscles gradually decrease in volume, mainly due to a reduced number of motor units and muscle fibers, and a reduced size of type 2 fibers. As a result, progressive weakening and impaired mobility occur. High‐resistance strength training is beneficial, even in the very old, and could possibly reverse some of the detrimental effects of age‐related weakness. The importance of exercise for older people affords an excellent opportunity for the medicine community as a major source of information and promotion of physical activity for this rapidly growing segment of the population. In this review, we summarize the current knowledge of the effects of aging on the human neuromuscular system, describe some of the major underlying mechanisms of the aging atrophy and focus on the importance of strength training to improve muscle function in older people.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Exercise training and nutritional supplementation for physical frailty in very elderly people
Fiatarone, M. A., O'Neill, E. F., Ryan, N. D., Clements, K. M., Solares, G. R., Nelson, M. E., Roberts, S. B., Kehayias, J. J., Lipsitz, L. A., & Evans, W. J. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406233302501 · Cited by 2,857
Data on the distribution of fibre types in thirty-six human muscles
Johnson, M. A., Polgar, J., Weightman, D., & Appleton, D. (1973) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(73)90023-3 · Cited by 2,200
High-Intensity Strength Training in Nonagenarians: Effects on Skeletal Muscle
Fiatarone, M. A. (1990) · JAMA · doi:10.1001/jama.1990.03440220053029 · Cited by 1,593
Neural adaptation to resistance training
SALE, D. G. (1988) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-198810001-00009 · Cited by 1,421
Leg extensor power and functional performance in very old men and women.
Bassey, E. J., Fiatarone, M. A., O'neill, E. F., Kelly, M., Evans, W. J., & Lipsitz, L. A. (1992) · Clinical Science · doi:10.1042/cs0820321 · Cited by 943
In Search of Methuselah: Estimating the Upper Limits to Human Longevity
Olshansky, S. J., Carnes, B. A., & Cassel, C. (1990) · Science · doi:10.1126/science.2237414 · Cited by 645
Lexell, J., Henriksson‐Larsén, K., Winblad, B., & Sjöström, M. (1983) · Muscle & Nerve · doi:10.1002/mus.880060809 · Cited by 582
Self-citationGrimby, G., & Saltin, B. (1983) · Clinical Physiology · doi:10.1111/j.1475-097x.1983.tb00704.x · Cited by 513
Potential for gross muscle hypertrophy in older men
Moritani, T., & Devries, H. A. (1980) · Journal of Gerontology · doi:10.1093/geronj/35.5.672 · Cited by 362
Positive adaptations to weight-lifting training in the elderly
Brown, A. B., McCartney, N., & Sale, D. G. (1990) · Journal of Applied Physiology · doi:10.1152/jappl.1990.69.5.1725 · Cited by 360
Cited by
Fielding, R. A., Vellas, B., Evans, W. J., Bhasin, S., Morley, J. E., Newman, A. B., Abellan van Kan, G., Andrieu, S., Bauer, J., Breuille, D., et al. (2011) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2011.01.003 · Cited by 3,256
“Type II fibers demonstrate selective atrophy (with a preservation of Type I fiber area) with age (19, 20).”
BackgroundInvited Review: Aging and sarcopenia
Doherty, T. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00347.2003 · Cited by 1,764
Aging of skeletal muscle: a 12-yr longitudinal study
Frontera, W. R., Hughes, V. A., Fielding, R. A., Fiatarone, M. A., Evans, W. J., & Roubenoff, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.4.1321 · Cited by 1,443
Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives
Rolland, Y., Czerwinski, S., van Kan, G. A., Morley, J. E., Cesari, M., Onder, G., Woo, J., Baumgartner, R., Pillard, F., Boirie, Y., et al. (2008) · The Journal of nutrition, health and aging · doi:10.1007/bf02982704 · Cited by 1,071
Häkkinen, K., Kallinen, M., Izquierdo, M., Jokelainen, K., Lassila, H., Mälkiä, E., Kraemer, W. J., Newton, R. U., & Alen, M. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.84.4.1341 · Cited by 776
Metadata
- Authors
- Porter, M. M., Vandervoort, A. A., & Lexell, J.
- Venue
- Scandinavian Journal of Medicine & Science in Sports
- Publisher
- Wiley
- Published
- 1995-06
- Volume
- 5
- Issue
- 3
- Pages
- 129-142
- ISSN
- 0905-7188 (ISSN-L)
- 1600-0838
- OpenAlex
- W2119627241
- Cited by
- 555
- References
- 14
- FWCI
- 5.70
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Aging of human muscle: structure, function and adaptability. https://app.cochat.ai/papers/10.1111/j.1600-0838.1995.tb00026.x
- The paper
- Porter, M. M., Vandervoort, A. A., & Lexell, J. (1995). Aging of human muscle: structure, function and adaptability. Scandinavian Journal of Medicine & Science in Sports. https://doi.org/10.1111/j.1600-0838.1995.tb00026.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
