Brief report: validity of Finnish registry‐based diagnoses of autism with the ADI‐R
Abstract
Aims: The aim of the study was to explore the validity of registry‐based diagnoses of autism in Finland using the Autism Diagnostic Interview – Revised (ADI‐R). This study was designed for the Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FIPS‐A), an ongoing research project where registry‐based diagnoses will be used for epidemiological studies. Methods: In this small pilot study, a clinical sample of 95 subjects diagnosed with childhood autism or pervasive developmental disorder/pervasive developmental disorder – not otherwise specified (PDD/PDD‐NOS) or Asperger′s syndrome according to the Finnish Hospital Discharge Register (FHDR) was gathered nationwide. A small control group consisting of siblings without any registered diagnoses of those being examined was also included in the study. Diagnoses were further re‐evaluated by interviewing parents with the ADI‐R. Results: The mean scores of autistic subjects clearly exceeded cut‐off limits for autism on all three ADI‐R domains and 96% of the subjects with registered diagnosis of childhood autism fulfilled the criteria based on the instrument as well. Conclusion: These results suggest that the validity of Finnish registry‐based diagnoses of childhood autism can be considered good. Our findings lay important groundwork for further population‐ based studies of the aetiology of autism.
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Among 80 cases of infantile autism from the Finnish Hospital and Outpatient Discharge Registry assessed with the ADI-R, 77 (96%) met criteria for childhood autism.
“In order to validate the registry diagnoses, 80 cases of infantile autism from the Finnish Hospital and Outpatient Discharge Registry were assessed using the Autism Diagnostic Interview-Revised (ADI-R). Among these cases, 77 (96%) met the criteria for childhood autism by the ADI-R23.”
From Elevated maternal C-reactive protein and autism in a national birth cohort (2014) · cites this paper as [23]
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Self-citation
- Authors
- Lampi, K., Sourander, A., Gissler, M., Niemelä, S., Rehnström, K., Pulkkinen, E., Peltonen, L., & Von Wendt, L.
- Affiliations
- University of Turku (FI)
- Finnish Institute for Health and Welfare (FI)
- Broad Institute (US)
- Venue
- Acta Paediatrica
- Publisher
- Wiley
- Published
- 2010-08-17
- Volume
- 99
- Issue
- 9
- Pages
- 1425-1428
- ISSN
- 0365-1436 (ISSN-L)
- 0803-5253
- 1651-2227
- OpenAlex
- W2152025705
- Cited by
- 91
- References
- 14
- Citations by year
- 2025: 3 · 2024: 5 · 2023: 6 · 2022: 8 · 2021: 9 · 2020: 7 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 6 · 2014: 9 · 2013: 13 · 2012: 7
- FWCI
- 4.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Paediatrica (publishedVersion)
- PubMed (publishedVersion)
- STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
- Funders
- Autism Speaks
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Keywords
- autism spectrum disorder, ADI-R, diagnostic validity, hospital discharge registry, pervasive developmental disorders, Asperger syndrome, childhood autism, autism epidemiology, Finland
- MeSH terms
- Autistic Disorder, Child, Child Development Disorders, Pervasive, Finland, Humans, Interview, Psychological, Pilot Projects, Registries, Reproducibility of Results, Case-Control Studies, Asperger Syndrome
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