Cited by 87Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Coagulation and inflammatory markers in Alzheimer's and vascular dementia

Gupta, A., Watkins, A., Thomas, P., Majer, R., Habubi, N., Morris, G., Pansari, K.·2004·International Journal of Clinical Practice

Abstract

Alzheimer's disease is classified as a degenerative dementia while vascular dementia is known to be associated with atherothrombosis and classical vascular risk factors. However, over the last decade, there is increasing evidence of the role of haemostatic factors and inflammatory mechanisms in the pathogenesis of Alzheimer's disease. Serum markers of hypercoagulability and markers of inflammation could lead to thrombosis, accelerated atherogenesis and resulting dementia of both Alzheimer's and vascular dementia. In this case control study, we studied these serum markers of coagulation and inflammation in patients suffering from dementia.

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Crossref · 10.1111/j.1742-1241.2004.00143.x

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62 of 62 references verified0 citation errors · 0 not checkable

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Authors
Gupta, A., Watkins, A., Thomas, P., Majer, R., Habubi, N., Morris, G., & Pansari, K.
Affiliations
Glangwili General Hospital (GB)
Corresponding author
Gupta, A.
Venue
International Journal of Clinical Practice
Publisher
Wiley
Published
2004-12-23
Volume
59
Issue
1
Pages
52-57
ISSN
1368-5031 (ISSN-L)
OpenAlex
W2149524374
Cited by
87
References
62
Citations by year
2026: 1 · 2025: 2 · 2024: 7 · 2023: 3 · 2022: 3 · 2021: 10 · 2020: 2 · 2019: 7 · 2018: 3 · 2017: 5 · 2016: 5 · 2015: 4 · 2014: 3 · 2013: 4 · 2012: 1
FWCI
1.88
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Clinical Practice (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Keywords
Alzheimer's disease, vascular dementia, hypercoagulability, coagulation markers, inflammatory markers, hemostatic factors, atherothrombosis, atherogenesis, dementia pathogenesis, serum biomarkers
MeSH terms
Alzheimer Disease, Analysis of Variance, Blood Coagulation Disorders, Blood Coagulation Factors, Blood Coagulation Tests, Fibrinogen, Humans, Inflammation, Risk Factors, Dementia, Vascular, Biomarkers, Case-Control Studies

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