Cited by 767Hormonal and reproductive studiesHypothalamic control of reproductive hormonesAdrenal Hormones and Disorders

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Prevalence of hypogonadism in males aged at least 45 years: the HIM study

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MULLIGAN, T., FRICK, M. F., ZURAW, Q. C., STEMHAGEN, A., MCWHIRTER, C.·2008·International Journal of Clinical Practice

DOI 10.1111/j.1742-1241.2006.00992.xPMC PMC1569444

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Abstract

The Hypogonadism in Males study estimated the prevalence of hypogonadism [total testosterone (TT) < 300 ng/dl] in men aged > or = 45 years visiting primary care practices in the United States. A blood sample was obtained between 8 am and noon and assayed for TT, free testosterone (FT) and bioavailable testosterone (BAT). Common symptoms of hypogonadism, comorbid conditions, demographics and reason for visit were recorded. Of 2162 patients, 836 were hypogonadal, with 80 receiving testosterone. Crude prevalence rate of hypogonadism was 38.7%. Similar trends were observed for FT and BAT. Among men not receiving testosterone, 756 (36.3%) were hypogonadal; odds ratios for having hypogonadism were significantly higher in men with hypertension (1.84), hyperlipidaemia (1.47), diabetes (2.09), obesity (2.38), prostate disease (1.29) and asthma or chronic obstructive pulmonary disease (1.40) than in men without these conditions. The prevalence of hypogonadism was 38.7% in men aged > or = 45 years presenting to primary care offices.

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Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men
Harman, S. M., Metter, E. J., Tobin, J. D., Pearson, J., & Blackman, M. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7219 · Cited by 2,760
Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study
Feldman, H. A., Longcope, C., Derby, C. A., Johannes, C. B., Araujo, A. B., Coviello, A. D., Bremner, W. J., & McKinlay, J. B. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8201 · Cited by 1,861
Age, Disease, and Changing Sex Hormone Levels in Middle-Aged Men: Results of the Massachusetts Male Aging Study*
Gray, A., Feldman, H. A., McKinlay, J. B., & Longcope, C. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-5-1016 · Cited by 1,104
Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men
Morley, J. E., Kaiser, F. E., Perry, H. M., Patrick, P., Morley, P. M. K., Stauber, P. M., Vellas, B., Baumgartner, R. N., & Garry, P. J. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90057-3 · Cited by 830
Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study
Araujo, A. B., O’Donnell, A. B., Brambilla, D. J., Simpson, W. B., Longcope, C., Matsumoto, A. M., & McKinlay, J. B. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031719 · Cited by 591
Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men
Bèlanger, A., Candas, B., Dupont, A., Cusan, L., Diamond, P., Gomez, J.-L., & Labrie, F. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.4.7962278 · Cited by 437
American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Evaluation and Treatment of Hypogonadism in Adult Male Patients—2002 Update
Petak, S. M., Nankin, H. R., Spark, R. F., Swerdloff, R. S., Rodriguez‐Rigau, L. J., Anderson, R. J., Bergman, D. A., Garber, J. R., Hamilton, C. R., Hershon, K. S., et al. (2002) · Endocrine Practice · doi:10.4158/ep.8.6.439 · Cited by 372
Plasma Free and Non-Sex-Hormone-Binding-Globulin Bound Testosterone Are Decreased in Obese Men in Proportion to Their Degree of Obesity
ZUMOFF, B., STRAIN, G. W., MILLER, L. K., ROSNER, W., SENIE, R., SERES, D. S., & ROSENFELD, R. S. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-71-4-929 · Cited by 349
Blood Testosterone Threshold for Androgen Deficiency Symptoms
Kelleher, S., Conway, A. J., & Handelsman, D. J. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0143 · Cited by 273
Serum androgen concentrations in young men: a longitudinal analysis of associations with age, obesity, and race. The CARDIA male hormone study.
Gapstur, S. M., Gann, P. H., Kopp, P. A., Colangelo, L. A., Longcope, C., & Liu, K. (2002) · PubMed · Cited by 247

Show all 24 references

Research works printed but not linked: 2

Population Division US Census Bureau, 2005, Table 2: Annual estimates of the population by sex and selected age groups for the United States: April 1, 2000 to July 1, 2003 (NC-EST2003-02)
Centers for Disease Control, 2005, About minority health

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Self-citation
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Stahlman, J., Britto, M. R., Fitzpatrick, S. B., McWhirter, C. L., Testino, S. A., Brennan, J. J., & ZumBrunnen, T. L. (2011) · Current Medical Research and Opinion · doi:10.1185/03007995.2011.652731 · Cited by 21
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Ferro, M., Lucarelli, G. T., COBELLI, O. D., Vartolomei, M. D., Damiano, R., Cantiello, F., Crocerossa, F., Perdonà, S., Prete, P. D., Cordima, G., et al. (2020) · World Journal of Urology · doi:10.1007/s00345-020-03368-9 · Cited by 20
Clinical Manual of Sexual Disorders
Balon, R., & Segraves, R. T. (2010) · Cited by 20
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Hall, S. A., Ranganathan, G., TINSLEY, L. J., Lund, J. L., Kupelian, V. A., Wittert, G., Kantoff, P. W., Morales, Á., & de Araújo, A. B. (2014) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.3579 · Cited by 19
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Earl, J. A., & Kim, E. D. (2019) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2019.1612239 · Cited by 19
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Kaplan, S. A., O’Neill, E. A., Lowe, R., Hanson, M. E., & Meehan, A. G. (2013) · The Aging Male · doi:10.3109/13685538.2013.773421 · Cited by 19
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Mousavi, S. A.-J., Kouchari, M.-R., Samdani-Fard, S. H., Gilvaee, Z. N., & Arabi, M. (2012) · Europe PMC (PubMed Central) · Cited by 19
Androgen effect on body weight and behaviour of male and female rats: novel insight on the clinical value
Alrabadi, N., Al-Rabadi, G. J., Maraqa, R., Sarayrah, H., Alzoubi, K. H., Alqudah, M., & Al-U'datt, D. G. F. (2020) · Andrologia · doi:10.1111/and.13730 · Cited by 18
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Marrachelli, V. G., Miranda, F. J., Centeno, J. M., Salom, J. B., Torregrosa, G., Jover‐Mengual, T., Pérez, A. M., Moro, M. Á., & Alborch, E. (2009) · Pharmacological Research · doi:10.1016/j.phrs.2009.06.008 · Cited by 17
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Fisher, W. A., Gruenwald, I., Jannini, E. A., Lev‐Sagie, A., Löwenstein, L., Pyke, R. E., Reisman, Y., Revicki, D. A., & Aurioles, E. R. (2017) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.08.016 · Cited by 18
STRONTIUM FRUCTOSE 1,6‐DIPHOSPHATE RESCUES ADENINE‐INDUCED MALE HYPOGONADISM AND UPREGULATES THE TESTICULAR ENDOTHELIN‐1 SYSTEM
Yu, F., Zhang, Q., Dai, D., Ying, H., & Dai, Y. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04693.x · Cited by 18
Testicular Disorders
Matsumoto, A. M., & Bremner, W. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00019-8 · Cited by 18
Testicular disorders.
Matsumoto, A. M., & Bremner, W. J. (2011) · Williams Textbook of Endocrinology · doi:10.1016/b978-1-4377-0324-5.00019-5 · Cited by 18
Office Evaluation of Male Sexual Dysfunction
Seftel, A. D., Miner, M. M., Kloner, R. A., & Althof, S. E. (2007) · Urologic Clinics of North America · doi:10.1016/j.ucl.2007.08.004 · Cited by 18
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Kamenov, Z. A. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.02148.x · Cited by 17
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Blick, G. (2013) · Postgraduate Medicine · doi:10.3810/pgm.2013.03.2639 · Cited by 17

Authors: MULLIGAN, T., FRICK, M. F., ZURAW, Q. C., STEMHAGEN, A., & MCWHIRTER, C.
Affiliations: University of Florida (US)
Covance (United States) (US)
Solvay (United States) (US)
Corresponding author: MULLIGAN, T.
ORCID: MULLIGAN, T.
Venue: International Journal of Clinical Practice
Publisher: Hindawi Limited
Published: 2008-10-09
Volume: 60
Issue: 7
Pages: 762-769
ISSN: 1368-5031 (ISSN-L)
DOI: 10.1111/j.1742-1241.2006.00992.x
PMC: PMC1569444
OpenAlex: W1667402504
Cited by: 767
References: 24
Citations by year: 2026: 14 · 2025: 37 · 2024: 37 · 2023: 32 · 2022: 35 · 2021: 42 · 2020: 44 · 2019: 38 · 2018: 34 · 2017: 54 · 2016: 60 · 2015: 40 · 2014: 58 · 2013: 60 · 2012: 42
FWCI: 18.19
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 2518 d)
Locations: International Journal of Clinical Practice (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: hypogonadism, androgen deficiency, prevalence, primary care, free testosterone, bioavailable testosterone, comorbidities, hypertension, hyperlipidemia, diabetes mellitus, obesity, prostate diseases, asthma, chronic obstructive pulmonary disease, testosterone replacement therapy
MeSH terms: Aged, Aged, 80 and over, Humans, Hypogonadism, Male, Middle Aged, Testosterone, United States, Prevalence

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Prevalence of hypogonadism in males aged at least 45 years: the HIM study

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