Quality of life and childhood atopic dermatitis: the misery of living with childhood eczema: ATOPIC ECZEMA/QUALITY OF LIFE
Open accessAbstract
The misery of living with atopic eczema (syn. dermatitis, AD) cannot be overstated for it may have a profoundly negative effect on the health-related quality of life (HRQoL) of children and their family unit in many cases. As it is one of the commonest chronic relapsing childhood dermatosis (UK lifetime prevalence 16-20% by 20 years), with increasing worldwide prevalence, this has major social and financial implications for individuals, healthcare providers and society as a whole. This review explores the impact of AD on the lives of children and their family units and the use of some of the recently developed HRQoL measures, which have enabled investigation and categorisation of the physical, psychological and psycho-social effects of childhood eczema across all aspects of life. These effects include symptoms of itching and soreness, which cause sleeplessness in over 60%. Sleep deprivation leads to tiredness, mood changes and impaired psychosocial functioning of the child and family, particularly at school and work. Embarrassment, comments, teasing and bullying frequently cause social isolation and may lead to depression or school avoidance. The child's lifestyle is often limited, particularly in respect to clothing, holidays, staying with friends, owning pets, swimming or the ability to play or do sports. Restriction of normal family life, difficulties with complicated treatment regimes and increased work in caring for a child with eczema lead to parental exhaustion and feelings of hopelessness, guilt, anger and depression. The hidden costs involved in eczema management can be significant and have particular impact on lower income families. The impairment of quality of life caused by childhood eczema has been shown to be greater than or equal to other common childhood diseases such as asthma and diabetes, emphasising the importance of eczema as a major chronic childhood disease. HRQoL measures are proving to be valuable tools for use in the clinical setting, as outcome measures for pharmaceutical studies, for health economics and audit purposes. It is therefore recommended that in future, they should be used in conjunction with objective measures of severity, as part of the assessment process of a child with atopic eczema. Lack of information on eczema and treatments heightens parental anxiety. Education of all individuals involved in the care of children with eczema is fundamental in the management of AD and it is essential to provide simple clear, unambiguous information on treatment and disease management in order to reduce the negative impact on HRQoL.
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Extant evidence indicates a positive association between the severity of eczema symptoms in children and feelings of helplessness in their parents.
“Extant evidence indicates a positive association between the severity of eczema symptoms in children and adverse mental health consequences in their parents, such as symptoms of depression and anxiety [15,16], feelings of helplessness [17], and heightened levels of worry, exhaustion, and stress [18,19].”
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- Authors
- LEWIS-JONES, S.
- Venue
- International Journal of Clinical Practice
- Publisher
- Wiley
- Published
- 2006-07-12
- Volume
- 60
- Issue
- 8
- Pages
- 984-992
- ISSN
- 1368-5031 (ISSN-L)
- OpenAlex
- W1776228394
- Cited by
- 478
- References
- 77
- Citations by year
- 2026: 12 · 2025: 23 · 2024: 35 · 2023: 26 · 2022: 28 · 2021: 21 · 2020: 29 · 2019: 27 · 2018: 32 · 2017: 24 · 2016: 41 · 2015: 43 · 2014: 22 · 2013: 18 · 2012: 21
- FWCI
- 1.99
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Keywords
- pediatric atopic dermatitis, atopic dermatitis, health-related quality of life, sleep deprivation, pruritus, bullying, social isolation, parental burden, psychosocial impact, economic burden, patient education, chronic childhood diseases
- MeSH terms
- Activities of Daily Living, Attitude to Health, Mental Disorders, Child, Dermatitis, Atopic, Family Health, Humans, Parents, Quality of Life, Severity of Illness Index, Sleep Wake Disorders, Cost of Illness
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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