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Investigating Women's Preference for Sildenafil or Tadalafil Use by Their Partners with Erectile Dysfunction: The Partners' Preference Study
Abstract
Introduction: Several preference studies comparing a short-acting with a longer-acting phosphodiesterase type 5 inhibitor have been conducted in men. Most men in those studies preferred tadalafil rather than sildenafil, and recent post hoc analysis of one study described several factors associated with men's treatment preference. No prospective studies have investigated the woman partners' preferences. Aim: To investigate the treatment preference of women who were partners of men using oral medications for erectile dysfunction (ED) in a single-center open-label crossover study. Methods: One hundred heterosexual couples in stable relationships, with male partners having ED based on the erectile function subscale of the International Index of Erectile Function, were randomly assigned to receive sildenafil or tadalafil for a 12-week phase, followed by another 12-week period using the alternate drug. Male and female participants completed sexual event diaries during both study phases, and the female participants were interviewed at baseline, midpoint, and end of study. Main Outcome Measures: Primary outcome data were the women's final interviews during which they were asked which drug they preferred and their reasons for that preference. Results: A total of 79.2% of the women preferred their partners' use of tadalafil, while 15.6% preferred sildenafil. Preference was not affected by age or treatment order randomization. Women preferring tadalafil reported feeling more relaxed, experiencing less pressure, and enjoying a more natural or spontaneous sexual experience as reasons for their choice. Mean number of tablets used, events recorded, events per week, and days between events were not significantly different during each study phase. Conclusion: Women's preferences were similar to men when using these two drugs. While the women's reasons for preferring tadalafil emphasized relaxed, satisfying, longer-lasting sexual experiences, those preferring sildenafil focused on satisfaction and drug effectiveness for their partner.
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“Tadalafil was preferred by the female partner in 79.2%, while 15.6% preferred sildenafil.”
From Tadalafil in the treatment of erectile dysfunction (2008) · cites this paper as Conaglen and Conaglen 2008
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“The female partners reported more relaxed, more satisfying, and longer-lasting sexual experiences with tadalafil as compared with sildenafil (Conaglen and Conaglen 2008).”
From Tadalafil in the treatment of erectile dysfunction (2008) · cites this paper as Conaglen and Conaglen 2008
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“The Partner’s Preference Study was a randomized, crossover study from a single center comparing tadalafil and sildenafil in 100 couples with the male partner having ED (Conaglen and Conaglen 2008).”
From Tadalafil in the treatment of erectile dysfunction (2008) · cites this paper as Conaglen and Conaglen 2008
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Cites
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Impact of erectile dysfunction on quality of life: patient and partner perspectives
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Cited by
Psychological and interpersonal dimensions of sexual function and dysfunction
Brotto, L., Atallah, S., Johnson-Agbakwu, C., Rosenbaum, T., Abdo, C., Byers, E. S., Graham, C., Nobre, P., & Wylie, K. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.01.019 · Cited by 439
Yuan, J., Zhang, R., Yang, Z., Lee, J., Liu, Y., Tian, J., Qin, X., Ren, Z., Ding, H., Chen, Q., et al. (2013) · European Urology · doi:10.1016/j.eururo.2013.01.012 · Cited by 260
Tadalafil in the treatment of erectile dysfunction
Coward, R., & Carson, C. (2008) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s3336 · Cited by 138
Fisher, W. A., Eardley, I., McCabe, M., & Sand, M. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01432.x · Cited by 74
The role of the sexual partner in managing erectile dysfunction
Li, H., Gao, T., & Wang, R. (2016) · Nature Reviews Urology · doi:10.1038/nrurol.2015.315 · Cited by 65
Metadata
- Authors
- Conaglen, H. M., & Conaglen, J. V.
- Affiliations
- University of Waikato—Psychology , Hamilton , New Zealand
- University of Auckland—Faculty of Medical and Health Sciences , Hamilton , New Zealand
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-05-01
- Volume
- 5
- Issue
- 5
- Pages
- 1198-1207
- ISSN
- 1743-6109
- 1743-6095
- Cited by
- 39
- References
- 3
- Language
- en
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