Sexual Dysfunction, Depression, and the Impact of Antidepressants
Abstract
Sexual dysfunction is a common symptom of depression. Although decreased libido is most often reported, difficulties with arousal, resulting in vaginal dryness in women and erectile dysfunction in men, and absent or delayed orgasm are also prevalent. Sexual dysfunction is also a frequent adverse effect of treatment with most antidepressants and is one of the predominant reasons for premature drug discontinuation. Selective serotonin reuptake inhibitors are the most widely prescribed antidepressants and have significant effects on arousal and orgasm compared with antidepressants that target norepinephrine, dopamine, and melatonin systems. The availability of an antidepressant that does not cause or exacerbate sexual dysfunction represents an advance in pharmacotherapy for mood disorders and should reduce treatment noncompliance and decrease the need for switching antidepressants or adding antidotes. The purpose of this review was to provide an update on the prevalence, psychobiology, and relative adverse effect burden of sexual dysfunction associated with different antidepressants.
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Sexual dysfunction is also a common symptom of depression.
“Sexual dysfunction is also a common symptom of depression (526-530).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [527]
Cites
Sexual Dysfunction in the United States: Prevalence and Predictors
Laumann, E. O., Paik, A., & Rosen, R. C. (1999) · JAMA · doi:10.1001/jama.281.6.537 · Cited by 5,119 · see citing works
The Arizona Sexual Experience Scale (ASEX): Reliability and Validity
A. McGahuey, A. J. G. (2000) · Journal of Sex & Marital Therapy · doi:10.1080/009262300278623 · Cited by 1,155 · see citing works
Araujo, A. B., Durante, R., Feldman, H. A., Goldstein, I., & McKinlay, J. B. (1998) · Psychosomatic Medicine · doi:10.1097/00006842-199807000-00011 · Cited by 576 · see citing works
Prevalence of Sexual Dysfunction Among Newer Antidepressants
Clayton, A. H., Pradko, J. F., Croft, H. A., Montano, C. B., Leadbetter, R. A., Bolden-Watson, C., Bass, K. I., Donahue, R. M. J., Jamerson, B. D., & Metz, A. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0414 · Cited by 542 · see citing works
Montejo-gonzàlez, A. L., Llorca, G., Izquierdo, J. A., Ledesma, A., Bousono, M., Calcedo, A., Carrasco, J. L., Ciudad, J., Daniel, E., De LA Gandara, J., et al. (1997) · Journal of Sex & Marital Therapy · doi:10.1080/00926239708403923 · Cited by 505 · see citing works
Stahl, S. M., Grady, M. M., Moret, C., & Briley, M. (2005) · CNS Spectrums · doi:10.1017/s1092852900019726 · Cited by 462 · see citing works
Brain Activation during Human Male Ejaculation
Holstege, G., Georgiadis, J. R., Paans, A. M. J., Meiners, L. C., van der Graaf, F. H. C. E., & Reinders, A. A. T. S. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-27-09185.2003 · Cited by 424 · see citing works
Neuroanatomical Correlates of Visually Evoked Sexual Arousal in Human Males
Stoléru, S., Grégoire, M., Gérard, D., Decety, J., Lafarge, E., Cinotti, L., Lavenne, F., Bars, D. L., Vernet-Maury, E., Rada, H., et al. (1999) · Archives of Sexual Behavior · doi:10.1023/a:1018733420467 · Cited by 418 · see citing works
Sexual dysfunction before antidepressant therapy in major depression
Kennedy, S. H., Dickens, S. E., Eisfeld, B. S., & Bagby, R. M. (1999) · Journal of Affective Disorders · doi:10.1016/s0165-0327(99)00050-6 · Cited by 412 · see citing works
Self-citationThe Mechanism of Action of Novel Antipsychotic Drugs
Meltzer, H. Y. (1991) · Schizophrenia Bulletin · doi:10.1093/schbul/17.2.263 · Cited by 412 · see citing works
Löo, H., Hale, A. S., & haenen, H. D. (2002) · International Clinical Psychopharmacology · doi:10.1097/00004850-200209000-00004 · Cited by 359 · see citing works
The Changes in Sexual Functioning Questionnaire (CSFQ): development, reliability, and validity.
Clayton, A. H., McGarvey, E. L., & Clavet, G. J. (1997) · PubMed · Cited by 352 · see citing works
Antidepressant-Induced Sexual Dysfunction
Gregorian, R. S., Golden, K. A., Bahce, A., Goodman, C., Kwong, W. J., & Khan, Z. M. (2002) · Annals of Pharmacotherapy · doi:10.1345/aph.1a195 · Cited by 320 · see citing works
Mechanism of action of antidepressant medications.
Feighner, J. P. (1999) · PubMed · Cited by 319 · see citing works
Thase, M. E., Haight, B. R., Richard, N., Rockett, C. B., Mitton, M., Modell, J. G., VanMeter, S., Harriett, A. E., & Wang, Y. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0803 · Cited by 304 · see citing works
Hayes, R. D., Dennerstein, L., Bennett, C. M., & Fairley, C. K. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00768.x · Cited by 301 · see citing works
Placebo-controlled trial of agomelatine in the treatment of major depressive disorder
Kennedy, S. H., & Emsley, R. A. (2005) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2005.09.002 · Cited by 294 · see citing works
Self-citationDynamics of male sexual arousal: distinct components of brain activation revealed by fMRI
Ferretti, A., Caulo, M., Del Gratta, C., Di Matteo, R., Merla, A., Montorsi, F., Pizzella, V., Pompa, P., Rigatti, P., Rossini, P. M., et al. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.025 · Cited by 288 · see citing works
Casper, R. C. (1985) · Archives of General Psychiatry · doi:10.1001/archpsyc.1985.01790340082012 · Cited by 279 · see citing works
Sexual problems in healthy and depressed persons
Angst, J. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199807006-00001 · Cited by 273 · see citing works
Olié, J., & Kasper, S. F. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707007766 · Cited by 257 · see citing works
The ELIXIR study: evaluation of sexual dysfunction in 4557 depressed patients in France
Bonierbale, M., Lançon, C., & Tignol, J. (2003) · Current Medical Research and Opinion · doi:10.1185/030079902125001461 · Cited by 249 · see citing works
Risperidone Augmentation of Selective Serotonin Reuptake Inhibitors in Major Depression
Ostroff, R. B., & Nelson, J. C. (1999) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v60n0410 · Cited by 245 · see citing works
Keller, A., McGarvey, E. L., & Clayton, A. H. (2006) · Journal of Sex & Marital Therapy · doi:10.1080/00926230500232909 · Cited by 243 · see citing works
Hu, X. H., Bull, S. A., Hunkeler, E. M., Ming, E., Lee, J. Y., Fireman, B., & Markson, L. E. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n0712 · Cited by 235 · see citing works
Kennedy, S. H., Eisfeld, B. S., Dickens, S. E., Bacchiochi, J. R., & Bagby, R. M. (2000) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v61n0406 · Cited by 223 · see citing works
Self-citationDepression and sexual dysfunction
Baldwin, D. S. (2001) · British Medical Bulletin · doi:10.1093/bmb/57.1.81 · Cited by 217 · see citing works
Safety of mirtazapine: a review
Montgomery, S. A. (1995) · International Clinical Psychopharmacology · doi:10.1097/00004850-199512004-00006 · Cited by 215 · see citing works
Bobes, J., A-PORTILLA, M. P. G., Rejas, J., ndez, G. H., García-García, M., Rico‐Villademoros, F., & PORRAS, A. (2003) · Journal of Sex & Marital Therapy · doi:10.1080/713847170 · Cited by 213 · see citing works
Rosenberg, K. P., Bleiberg, K. L., KOSCIS, J., & GROSS, C. (2003) · Journal of Sex & Marital Therapy · doi:10.1080/00926230390195524 · Cited by 212 · see citing works
Kennedy, S. H., Rizvi, S. J., Fulton, K., & Rasmussen, J. (2008) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e318172b48c · Cited by 211 · see citing works
Self-citationWalter, M., Bermpohl, F., Mouras, H., Schiltz, K., Tempelmann, C., Rotte, M., Heinze, H. J., Bogerts, B., & Northoff, G. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.01.040 · Cited by 210 · see citing works
Regional cerebral blood flow changes associated with clitorally induced orgasm in healthy women
Georgiadis, J. R., Kortekaas, R., Kuipers, R., Nieuwenburg, A., Pruim, J., Reinders, A. A. T. S., & Holstege, G. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05206.x · Cited by 205 · see citing works
Anorgasmia from Clomipramine in Obsessive-Compulsive Disorder
Monteiro, W., Noshirvani, H., Marks, I. M., & Lelliott, P. T. (1987) · The British Journal of Psychiatry · doi:10.1192/bjp.151.1.107 · Cited by 202 · see citing works
Landén, M., Eriksson, E., Agren, H., & Fahlén, T. (1999) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199906000-00012 · Cited by 202 · see citing works
Sexual dysfunctions in depression
Mathew, R. J., & Weinman, M. L. (1982) · Archives of Sexual Behavior · doi:10.1007/bf01541593 · Cited by 196 · see citing works
Discontinuing or Switching Selective Serotonin-Reuptake Inhibitors
Bull, S. A., Hunkeler, E. M., Lee, J. Y., Rowland, C. R., Williamson, T. E., Schwab, J. R., & Hurt, S. W. (2002) · Annals of Pharmacotherapy · doi:10.1345/aph.1a254 · Cited by 191 · see citing works
Antidepressants and sexual dysfunction
Werneke, U., Northey, S., & Bhugra, D. (2006) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2006.00890.x · Cited by 176 · see citing works
Efficacy of Agomelatine in Generalized Anxiety Disorder
Stein, D. J., Ahokas, A., & de Bodinat, C. (2008) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e318184ff5b · Cited by 173 · see citing works
Coleman, C. C., King, B., Bolden-Watson, C., Book, M. J., Segraves, R., Richard, N., Ascher, J., Batey, S. R., Jamerson, B., & Metz, A. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80090-4 · Cited by 171 · see citing works
Multicenter, Placebo-Controlled, Fixed-Dose Study of Citalopram in Moderate-to-Severe Depression
Feighner, J. P., & Overø, K. F. (1999) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v60n1204 · Cited by 169 · see citing works
Corya, S. A. (2005) · doi:10.4088/jcp.v66n1012 · Cited by 162 · see citing works
Management of Patients With Treatment-Resistant Depression
Thase, M. E. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.0308e08 · Cited by 158 · see citing works
Lifetime Depression History and Sexual Function in Women at Midlife
Cyranowski, J. M., Bromberger, J. T., Youk, A. O., Matthews, K. A., Kravitz, H. M., & Powell, L. H. (2004) · Archives of Sexual Behavior · doi:10.1023/b:aseb.0000044738.84813.3b · Cited by 157 · see citing works
Clayton, A. H., Kornstein, S. G., Prakash, A., Mallinckrodt, C. H., & Wohlreich, M. M. (2007) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00520.x · Cited by 151 · see citing works
Davis, R., & Wilde, M. I. (1996) · CNS Drugs · doi:10.2165/00023210-199605050-00007 · Cited by 136 · see citing works
Delgado, P. L., Brannan, S. K., Mallinckrodt, C. H., Trân, P. V., McNamara, R. K., Wang, F., Watkin, J. G., & Detke, M. J. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0603 · Cited by 135 · see citing works
Liebowitz, M. R., Manley, A. L., Padmanabhan, S. K., Ganguly, R., Tummala, R., & Tourian, K. A. (2008) · Current Medical Research and Opinion · doi:10.1185/03007990802161923 · Cited by 134 · see citing works
Psychostimulant treatment of depressive disorders secondary to medical illness.
Woods, S., Tesar, G. E., Murray, G. B., & Cassem, N. H. (1986) · PubMed · Cited by 133 · see citing works
Sexual problems and help‐seeking behaviour in adults in the United Kingdom and continental Europe
Moreira, E. D., Glasser, D. B., Nicolosi, A., Duarte, F. G., Gingell, C., & for the GSSAB Investigators’ Group (2008) · British Journal of Urology · doi:10.1111/j.1464-410x.2008.07453.x · Cited by 132 · see citing works
Bupropion Extended Release Compared With Escitalopram
Clayton, A. H., Croft, H. A., Horrigan, J. P., Wightman, D. S., Krishen, A., Richard, N. E., & Modell, J. G. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n0507 · Cited by 127 · see citing works
The relationship between depression and erectile dysfunction
Seidman, S. N., & Roose, S. P. (2000) · Current Psychiatry Reports · doi:10.1007/s11920-996-0008-0 · Cited by 126 · see citing works
Papakostas, G. I., Petersen, T., Kinrys, G., Burns, A. M., Worthington, J. J., Alpert, J. E., D, M. F. M., & Nierenberg, A. A. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n1017 · Cited by 125 · see citing works
Michelson, D., Bancroft, J., Targum, S. D., Kim, Y., & Tepner, R. G. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.2.239 · Cited by 123 · see citing works
Ravindran, A. V., Kennedy, S. H., O'Donovan, M. C., Fallu, A., Camacho, F., & Binder, C. E. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0112 · Cited by 119 · see citing works
Self-citationSan, L., & Arranz, B. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2008.04.002 · Cited by 117 · see citing works
Papakostas, G. I., Stahl, S. M., Krishen, A., Seifert, C. A., Tucker, V. L., Goodale, E. P., & D, M. F. M. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0812 · Cited by 117 · see citing works
Clinical issues in long-term treatment with antidepressants.
Zajecka, J. M. (2000) · PubMed · Cited by 114 · see citing works
Williams, V. S. L., Baldwin, D. S., Hogue, S., Fehnel, S. E., Hollis, K. A., & Edin, H. M. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n0205 · Cited by 114 · see citing works
Labbate, L. A., Croft, H. A., & Oleshansky, M. A. (2003) · PubMed · Cited by 113 · see citing works
Shelton, R. C., & Papakostas, G. I. (2008) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.01130.x · Cited by 112 · see citing works
Human brain activation during sexual stimulation of the penis
Georgiadis, J. R., & Holstege, G. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20735 · Cited by 110 · see citing works
Burden of phase-specific sexual dysfunction with SSRIs☆
Clayton, A. H., KELLER, A., & McGarvey, E. L. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.12.007 · Cited by 109 · see citing works
Combined MAOI, TCA, and direct stimulant therapy of treatment-resistant depression.
Feighner, J. P., Herbstein, J., & Damlouji, N. F. (1985) · PubMed · Cited by 104 · see citing works
Mechanisms and treatments of SSRI-induced sexual dysfunction.
Keltner, N. L., McAfee, K. M., & Taylor, C. L. (2002) · PubMed · Cited by 101 · see citing works
Lithium, benzodiazepines, and sexual function in bipolar patients
Ghadirian, A. M., Annable, L., & Bélanger, M. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.6.801 · Cited by 101 · see citing works
Baldwin, D. S., Cooper, J. A., Huusom, A. K. T., & Hindmarch, I. (2006) · International Clinical Psychopharmacology · doi:10.1097/01.yic.0000194377.88330.1d · Cited by 100 · see citing works
Septien-Velez, L., Pitrosky, B., Padmanabhan, S. K., Germain, J., & Tourian, K. A. (2007) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e3281e2c84b · Cited by 96 · see citing works
Sexual Function during Bupropion or Paroxetine Treatment of Major Depressive Disorder
Kennedy, S. H., Fulton, K. A., Bagby, R. M., Greene, A. L., Cohen, N. L., & Rafi‐Tari, S. (2006) · The Canadian Journal of Psychiatry · doi:10.1177/070674370605100405 · Cited by 93 · see citing works
Self-citationA Double-blind Comparison Between Bupropion XL and Venlafaxine XR
Thase, M. E., Clayton, A. H., Haight, B. R., Thompson, A. H., Modell, J. G., & Johnston, J. A. (2006) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000239790.83707.ab · Cited by 90 · see citing works
Clayton, A. H., Zajecka, J., Ferguson, J. M., Filipiak‐Reisner, J. K., Brown, M. T., & Schwartz, G. E. (2003) · International Clinical Psychopharmacology · doi:10.1097/01.yic.0000066456.73432.09 · Cited by 89 · see citing works
Keltner, N. L., McAfee, K. M., & Taylor, C. L. (2009) · Perspectives In Psychiatric Care · doi:10.1111/j.1744-6163.2002.tb00665.x · Cited by 89 · see citing works
Genitourinary and Sexual Adverse Effects of Psychotropic Medication
Pollack, M. H., Reiter, S. R., & Hammerness, P. G. (1992) · The International Journal of Psychiatry in Medicine · doi:10.2190/p60r-pled-tl09-tuen · Cited by 88 · see citing works
Landén, M., Högberg, P., & Thase, M. E. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0114 · Cited by 81 · see citing works
Age of first onset of bipolar disorder: Demographic, family history, and psychosocial correlates
Hays, J. C., Krishnan, K., George, L. K., & Blazer, D. G. (1998) · Depression and Anxiety · doi:10.1002/(sici)1520-6394(1998)7:2 · Cited by 78 · see citing works
Effect of lamotrigine on sexual function in patients with epilepsy
Gil‐Nagel, A., Lopez-Munoz, F. J., Serratosa, J. M., Moncada, I., García, P. G., & Álamo, C. (2006) · Seizure · doi:10.1016/j.seizure.2005.12.006 · Cited by 76 · see citing works
Prospective assessment of sexual function in women treated for recurrent major depression
Cyranowski, J. M., Frank, E., Cherry, C. R., Houck, P. R., & Kupfer, D. J. (2003) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2003.08.003 · Cited by 76 · see citing works
Hirose, S., & Ashby, C. R. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0812 · Cited by 73 · see citing works
Baldwin, D. S., Bridgman, K. M., & Buis, C. (2005) · Journal of Psychopharmacology · doi:10.1177/0269881105056666 · Cited by 72 · see citing works
The pharmacological management of depression
Kupfer, D. J. (2005) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2005.7.3/dkupfer · Cited by 69 · see citing works
Özmenler, K. N., Karlıdere, T., Bozkurt, A., Yetki̇n, S., Doruk, A., Sütçigil, L., Cansever, A., Uzun, Ö., Özgen, F., & Özşahin, A. (2008) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.929 · Cited by 68 · see citing works
Waldinger, M. D., Zwinderman, A. H., & Olivier, B. (2003) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000088904.24613.e4 · Cited by 67 · see citing works
Invernizzi, R. W., Sacchetti, G., Parini, S., Acconcia, S., & SAMANIN, R. (2003) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705341 · Cited by 62 · see citing works
Why do we need new and better antidepressants?
Montgomery, S. (2006) · International Clinical Psychopharmacology · doi:10.1097/01.yic.0000199455.39552.1c · Cited by 59 · see citing works
Wade, A. G., Crawford, G. M., Angus, M., Wilson, R., & Hamilton, L. (2003) · International Clinical Psychopharmacology · doi:10.1097/01.yic.0000068045.82050.00 · Cited by 58 · see citing works
Melatonin protects against the effects of chronic stress on sexual behaviour in male rats
Brotto, L. A., Gorzalka, B. B., & LaMarre, A. K. (2001) · Neuroreport · doi:10.1097/00001756-200111160-00018 · Cited by 56 · see citing works
Eison, A. S., Freeman, R., Guss, V. B., et al. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)09543-6 · Cited by 55 · see citing works
van Geffen, E. C. G., van der Wal, S. W., van Hulten, R., de Groot, M., Egberts, T. C. G., & Heerdink, E. R. (2007) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-007-0375-4 · Cited by 55 · see citing works
Yang, J.-C., Park, K., Eun, S.-J., Lee, M.-S., Yoon, J., Shin, I., Kim, Y., Chung, T. W., Kang, H.-K., & Jeong, G. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00737.x · Cited by 55 · see citing works
Marangell, L. B., Johnson, C. R., Kertz, B. L., Zboyan, H. A., & Martinez, J. M. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0503 · Cited by 54 · see citing works
Combining Stimulants With Monoamine Oxidase Inhibitors
Feinberg, S. S. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n1113 · Cited by 53 · see citing works
Feiger, A. D., Heiser, J. F., Shrivastava, R. K., Weiss, K. J., Smith, W. T., Sitsen, J. M. A., & Gibertini, M. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0304 · Cited by 53 · see citing works
Montejo, A. L., Garcia, M., Espada, M., et al. (2000) · PubMed · Cited by 52 · see citing works
Survey of Treatment Practices for Sexual Dysfunction(s) Associated with Anti-Depressants
Balon, R., & Segraves, R. T. (2008) · Journal of Sex & Marital Therapy · doi:10.1080/00926230802096390 · Cited by 50 · see citing works
Lithium and Male Sexual Function in Affective Patients
Aizenberg, D., Sigler, M., Zemishlany, Z., & Weizman, A. (1996) · Clinical Neuropharmacology · doi:10.1097/00002826-199619060-00005 · Cited by 49 · see citing works
Efficacy and Tolerability of Reboxetine Compared with Citalopram
Langworth, S., Bodlund, O., & Ågren, H. (2006) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000204138.20417.c3 · Cited by 45 · see citing works
Changes in Sexual Function During Acute and Six-Month Fluoxetine Therapy: A Prospective Assessment
Michelson, M. (2001) · Journal of Sex & Marital Therapy · doi:10.1080/009262301750257146 · Cited by 42 · see citing works
Haberfellner, E. M. (2007) · Pharmacopsychiatry · doi:10.1055/s-2007-985881 · Cited by 40 · see citing works
Yang, J.-C. (2004) · Korean Journal of Radiology · doi:10.3348/kjr.2004.5.2.87 · Cited by 40 · see citing works
Sáiz-Ruiz, J., Montes, J. M. G., Ibáñez, Á., Díaz, M., Vicente, F., Pelegrín, C., Viñas, R., Árias, F., Carrasco, J. L., & Ferrando, L. (2005) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.706 · Cited by 39 · see citing works
Resolution of sexual dysfunction during acute treatment of major depression with milnacipran
Baldwin, D. S., Moreno, R. A., & Briley, M. (2008) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.955 · Cited by 34 · see citing works
The under-recognized role of dopamine in the treatment of major depressive disorder
Montgomery, S. (2008) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e3282f2b3cb · Cited by 31 · see citing works
Sexual side effects of alprazolam
Lydiard, R. B., Howell, E. F., Laraia, M. T., & Ballenger, J. C. (1987) · American Journal of Psychiatry · doi:10.1176/ajp.144.2.254b · Cited by 29 · see citing works
Sexual dysfunction and physicians' perception in medicated patients with major depression in Taiwan
Chen, K. C., Yang, Y. K., Lee, I. H., Yeh, T. L., Lu, R., & Chen, P. S. (2007) · Depression and Anxiety · doi:10.1002/da.20312 · Cited by 27 · see citing works
Spotlight on Bupropion in Major Depressive Disorder???
Dhillon, S., Yang, L. P. H., & Curran, M. P. (2008) · CNS Drugs · doi:10.2165/00023210-200822070-00006 · Cited by 25 · see citing works
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DE HERT, M., CORRELL, C. U., BOBES, J., CETKOVICH‐BAKMAS, M., COHEN, D., ASAI, I., DETRAUX, J., GAUTAM, S., MÖLLER, H., NDETEI, D. M., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00014.x · Cited by 2,488 · see citing works
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Gonçalves, W. S., Gherman, B. R., Abdo, C. H. N., Coutinho, E. S. F., Nardi, A. E., & Appolinario, J. C. (2023) · International Journal of Impotence Research · doi:10.1038/s41443-022-00539-7 · Cited by 60 · see citing works
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- Authors
- Kennedy, S. H., & Rizvi, S.
- Affiliations
- University Health Network (CA)
- Corresponding author
- Kennedy, Sidney H.
- Rizvi, Sakina
- ORCID
- Kennedy, Sidney H.
- Venue
- Journal of Clinical Psychopharmacology
- Published
- 2009-04
- Volume
- 29
- Issue
- 2
- Pages
- 157-164
- ISSN
- 0271-0749 (ISSN-L)
- OpenAlex
- W2158447906
- Cited by
- 338
- References
- 114
- Citations by year
- 2026: 10 · 2025: 14 · 2024: 17 · 2023: 21 · 2022: 18 · 2021: 24 · 2020: 12 · 2019: 13 · 2018: 22 · 2017: 23 · 2016: 24 · 2015: 17 · 2014: 19 · 2013: 31 · 2012: 21
- FWCI
- 3.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Keywords
- sexual dysfunction, depression, antidepressants, selective serotonin reuptake inhibitors, erectile dysfunction, female sexual dysfunction, orgasm, sexual desire, adverse drug reactions, treatment discontinuation, treatment non-adherence, norepinephrine, dopamine, melatonin
- MeSH terms
- Antidepressive Agents, Major Depressive Disorder, Female, Humans, Erectile Dysfunction, Libido, Male, Orgasm, Selective Serotonin Reuptake Inhibitors, Sexual Dysfunctions, Psychological, Medication Adherence
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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