Efficacy of Psychosocial Interventions in Men and Women with Sexual Dysfunctions—A Systematic Review of Controlled Clinical Trials
Abstract
INTRODUCTION: As yet, a summary of research evidence concerning the efficacy of psychological treatment in male sexual dysfunction is lacking. AIM: Our systematic review gives an overview of the efficacy of psychosocial interventions in all male sexual dysfunctions. MAIN OUTCOME MEASURES: Main outcome measures included, for example, psychometrically validated scales, interviews, and clinical assessment by an independent rater. The efficacy of psychosocial interventions was measured, for example, by the frequency of and satisfaction with sexual activity and sexual functioning. METHODS: The systematic literature search included electronic database search, handsearch, contact with experts, and an ancestry approach. Studies were included if the man was given a formal diagnosis of a sexual dysfunction (International Statistical Classification of Diseases and Related Health Problems [ICD10/-9]; Diagnostic and Statistical Manual of Mental Disorders [DSM-IV/-III-R]) and when the intervention was psychosocial or psychotherapeutic. The control group included either another treatment or a waiting-list control group. The report of relevant outcomes was necessary for inclusion as well as the design of the study (randomized controlled trials [RCTs] and controlled clinical trials [CCTs]). The assessment of methodological quality comprised aspects of randomization, blinding, incomplete outcome data, selective reporting, and allegiance. RESULTS: We identified 19 RCTs and one CCT that investigated the efficacy in male sexual dysfunction and two further studies that examined male and female sexual dysfunction together. Twelve out of 20 trials in men used either a concept derived from Masters and Johnson or a cognitive-behavioral treatment program. Overall, psychosocial interventions improved sexual functioning. While one study found that psychotherapy is superior to sildenafil, another study found the opposite. In men with premature ejaculation, behavioral techniques proved to be effective. A shortcoming was the rather low methodological quality of included studies. CONCLUSIONS: Most of the compared interventions proved to be similarly effective. Possibly, there are underlying constructs throughout all therapies that have an effect on the outcome.
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Psychological treatment can prevent recurrence of the sexual problem after treatment because men learn to manage dysfunctional response patterns associated with ED.
“Furthermore, psychological treatment can prevent the recurrence of the sexual problem after treatment because men learn to manage their dysfunctional response patterns associated with ED.108”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [108]
A multidisciplinary treatment combining medical and psychological treatment is more effective than mono-treatment.
“Statement #9: A multidisciplinary treatment, in which medical treatment is combined with psychological treatment, has proven to be more effective than mono-treatment (Level 2, Grade B).”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [108]
Psychological treatment programs commonly include psychoeducation, anxiety reduction and desensitization, cognitive therapy and sexual fantasy training, increasing sexual stimulation, and couple interventions.
“Psychological treatment programs commonly include the following components: psychoeducation; anxiety reduction and desensitization; cognitive therapy and sexual fantasy training; increasing sexual stimulation; and couple interventions.4,108,122”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [108]
Psychological treatment involves reducing anxiety, challenging cognitive beliefs, increasing sexual stimulation, disrupting sexual avoidance, and interpersonal interventions such as communication skills training.
“Statement #15: Psychological treatment involves reducing anxiety, challenging cognitive beliefs, increasing sexual stimulation, disrupting sexual avoidance, and interpersonal interventions such as communication skills training (Level 2, Grade B).”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [108]
Available studies on the effectiveness of psychological treatments are limited and hampered by small sample sizes, inadequate follow-up, and a lack of controlled designs.
“In addition, available studies on the effectiveness of psychological treatments are limited and hampered by small samples sizes, inadequate follow-up, and a lack of controlled designs.106, 107, 108”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [108]
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“In a systematic review, 13 randomized controlled trials that investigated psychosocial interventions in men with ED were identified; overall, interventions were successful.(312) In contrast, another meta-analysis found only non-significant, moderate effect sizes of psychological therapy for ED.”
BackgroundMethodAlthof, S. E., McMahon, C. G., Waldinger, M. D., Şerefoğlu, E. C., Shindel, A. W., Adaikan, P. G., Becher, E. F., Dean, J. P., Giuliano, F., Hellstrom, W. J. G., et al. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12504 · Cited by 286 · see citing works
Group mindfulness-based therapy significantly improves sexual desire in women
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Female Sexual Dysfunction—Medical and Psychological Treatments, Committee 14
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Self-citationCarr, A. (2014) · Journal of Family Therapy · doi:10.1111/1467-6427.12033 · Cited by 107 · see citing works
“Systematic reveiws and a major meta-analysis conclude that couples treated with psychosocial interventions show greater improvemnts than untreated controls (Berner and Günzler, 2012; Frühauf et al., 2013; Günzler and Berner, 2012).”
BackgroundCarr, A. (2018) · Journal of Family Therapy · doi:10.1111/1467-6427.12225 · Cited by 115 · see citing works
The Heteronormativity Theory of Low Sexual Desire in Women Partnered with Men
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“As with mindfulness-based therapy, however, a closer look at the CBT findings also connects low desire in women partnered with men to larger, structural problems related to gender.”
BackgroundInfluentialDewitte, M., Bettocchi, C., Carvalho, J., Corona, G., Flink, I., Limoncin, E., Pascoal, P., Reisman, Y., & Van Lankveld, J. (2021) · Sexual Medicine · doi:10.1016/j.esxm.2021.100434 · Cited by 97 · see citing works
“Furthermore, psychological treatment can prevent the recurrence of the sexual problem after treatment because men learn to manage their dysfunctional response patterns associated with ED.(108) Hence, whereas medical treatments are directed towards treating the symptoms, that is, restoring erection, psychological treat…”
BackgroundPyke, R. E., & Clayton, A. H. (2015) · The Journal of Sexual Medicine · doi:10.1111/jsm.13056 · Cited by 84 · see citing works
Schmidt, H. M., Munder, T., Gerger, H., Frühauf, S., & Barth, J. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12520 · Cited by 84 · see citing works
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2016 United Kingdom national guideline on the sexual health care of men who have sex with men
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“Presently, empirical research documenting the development and evaluation of psychosocial treatments is limited, and what research does exist is criticized for its low quality.(14,15) For example, there is, as of yet, no consensus on the number of psychological treatment sessions, partner involvement, theoretical orien…”
BackgroundZarski, A., Berking, M., Fackiner, C., Rosenau, C., & Ebert, D. D. (2017) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.12.232 · Cited by 51 · see citing works
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Kane, L., Dawson, S. J., Shaughnessy, K., Reissing, E. D., Ouimet, A. J., & Ashbaugh, A. R. (2019) · Journal of Experimental Psychopathology · doi:10.1177/2043808719847371 · Cited by 48 · see citing works
“A comprehensive review of all cognitive behavioral interventions for sexual dysfunction is beyond the scope of this article (for systematic reviews, see Berner & Günzler, 2012; Günzler & Berner, 2012; for a meta-analysis, see Frühauf, Gerger, Schmidt, Munder, & Barth, 2013).”
Basson, R. J., O’Loughlin, J. I., Weinberg, J., Young, A. H., Bodnar, T. S., & Brotto, L. A. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.03.001 · Cited by 39 · see citing works
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“When reviewing the literature on CBT and sexual dysfunction, Jaspers et al. (2016) found a clear gender disparity in that of 19 Randomized Control Trials (RCTs) for therapeutic intervention for sexual dysfunction, only one included men (Berner & Gunzler, 2012).”
BackgroundFlibanserin for the treatment of hypoactive sexual desire disorder in premenopausal women
Dhanuka, I., & Simon, J. A. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.1090426 · Cited by 34 · see citing works
Health Professions Students’ Perceptions of Sexuality in Patients with Physical Disability
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Nobre, P. J. (2013) · Wiley eBooks · doi:10.1002/9781118528563.wbcbt28 · Cited by 31 · see citing works
The sexual dysfunctions and paraphilias
Graham, C. A., & Bancroft, J. (2020) · doi:10.1093/med/9780198713005.003.0115 · Cited by 29 · see citing works
Zarski, A., Berking, M., & Ebert, D. D. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00260 · Cited by 30 · see citing works
Future Targets for Female Sexual Dysfunction
Farmer, M. A., Yoon, H., & Goldstein, I. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.05.016 · Cited by 28 · see citing works
Tüken, M., Kiremit, M. C., & Şerefoğlu, E. C. (2016) · Urology · doi:10.1016/j.urology.2016.04.036 · Cited by 22 · see citing works
Challenges in Designing Psychological Treatment Studies for Sexual Dysfunction
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Management and rehabilitation of neurologic patients with sexual dysfunction.
Basson, R., & Bronner, G. (2015) · Handbook of Clinical Neurology · doi:10.1016/b978-0-444-63247-0.00024-9 · Cited by 12 · see citing works
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Therapeutic management of erectile dysfunction: The AFU/SFMS guidelines
Huyghe, É., Kassab, D., Graziana, J. P., Faix, A., Grellet, L., Schoentgen, N., de Hauteclocque, A. B., Dupuis, H. G. A., Chebbi, A., Chelghaf, I., et al. (2024) · The French Journal of Urology · doi:10.1016/j.fjurol.2024.102842 · Cited by 14 · see citing works
Bibliotherapy for Sexual Dysfunctions: A Systematic Review and Meta-Analysis
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Einfluss von Paarinteraktion auf die Gesundheit
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Efficacy of metacognitive therapy for hypoactive sexual desire disorder among Iranian couples
Ramezani, M. A., Ahmadi, K., Besharat, M., Noohi, S., & Ghaemmaghami, A. (2017) · Psychotherapy Research · doi:10.1080/10503307.2017.1301690 · Cited by 13 · see citing works
“…three systematic reviews and meta-analyses determined the efficacy of MJST, but they found the effect size of the approach was low and importantly, a relapse was evident after 6 months (Berner & Gunzler, 2012; Gunzler & Berner, 2012; Pereira, AriasCarrion, Machado, Nardi, & Silva, 2013).”
BackgroundLoss of Libido in a Woman With Schizophrenia
Seeman, M. V. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12111475 · Cited by 13 · see citing works
Couple therapy and systemic interventions for adult‐focused problems: The evidence base
Carr, A. (2025) · Journal of Family Therapy · doi:10.1111/1467-6427.12481 · Cited by 16 · see citing works
Perception of Men's Beauty and Attractiveness by Women with Low Sexual Desire
Ferdenzi, C., Delplanque, S., Vorontsova-Wenger, O., Pool, E. R., Bianchi‐Demicheli, F., & Sander, D. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12795 · Cited by 12 · see citing works
Sexualität bei Übergewicht und Adipositas
Abrahamian, H., & Kautzky‐Willer, A. (2016) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-016-0430-9 · Cited by 12 · see citing works
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Evaluation of a rural nurse-led clinic for female sexual dysfunction
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Cognitive Behavioral Therapy in Sexual Dysfunction
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Zarski, A., Berking, M., Hannig, W., & Ebert, D. D. (2018) · Verhaltenstherapie · doi:10.1159/000485041 · Cited by 6 · see citing works
A Brief Online Mindfulness Intervention for Women’s Sexual Desire: The BROWSE Study
Xue, A., Makarenko, B., & Brotto, L. A. (2024) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2024.2343286 · Cited by 5 · see citing works
“Given that partner presence has been identified as a significant predictor in better outcomes during sex therapy (Berner & Gunzler, 2012), the lack of partner exercises may have limited participant improvement.”
BackgroundConnaughton, C., & McCabe, M. P. (2017) · Wiley eBooks · doi:10.1002/9781118510384.ch30 · Cited by 5 · see citing works
The premature ejaculation ‘disorder’: Questioning the criterion of one minute of penetration
Kempeneers, P., & Desseilles, M. (2014) · Sexologies · doi:10.1016/j.sexol.2014.06.004 · Cited by 4 · see citing works
Psychotherapy for Sexual Dysfunctions
Reddy, A. S. (2018) · Springer eBooks · doi:10.1007/978-981-13-1226-7_9 · Cited by 4 · see citing works
Uğurlu, G. K., & Ugurlu, M. M. (2020) · Ankara Medical Journal · doi:10.5505/amj.2020.86547 · Cited by 4 · see citing works
Flibanserin for postmenopausal women—Are they really that different?
Simon, J. A., & Dhanuka, I. (2015) · Maturitas · doi:10.1016/j.maturitas.2015.09.008 · Cited by 4 · see citing works
L'éjaculation précoce : une revue de questions Premature ejaculation: A review of topics
Kempeneers, P., Andrianne, R., Lequeux, A., & Blairy, S. (2014) · Cited by 3 · see citing works
Standards in Studies of Psychotherapy and Pharmacotherapy Interventions for HSDD
Clayton, A. H., & Pyke, R. E. (2016) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2016.1217296 · Cited by 3 · see citing works
“But in the cited meta-analysis (Frühauf, Gerger, Schmidt, Munder, & Barth, 2013) and the systematic review (Gunzler & Berner, 2012), no control data except the wait-list subjects were available with which to calculate effect size, using a lower level of evidence and removing the response from any…”
MethodKadın cinsel işlev bozukluğu yönetiminde güncel yaklaşımlar ve kanıt temelli uygulamalar
BEKMEZCİ, E., & Meram, H. E. (2020) · Androloji Bülteni · doi:10.24898/tandro.2020.44977 · Cited by 3 · see citing works
Diagnóstico, tratamiento y seguimiento de la eyaculación precoz: recomendaciones de experto
Prieto, R., Cruz, N., Cabello, F., García, F., Fernández, A., Larrazábal, M., Martín, A., Sánchez, F. S., Martín, C. S., & Viladoms, J. M. (2017) · Revista Internacional de Andrología · doi:10.1016/j.androl.2017.01.004 · Cited by 3 · see citing works
Depression, Antidepressants, and Sexual Functioning
Dording, C. M., & Boyden, S. (2018) · Springer eBooks · doi:10.1007/978-3-319-97241-1_9 · Cited by 3 · see citing works
Abrams, M. (2019) · Springer eBooks · doi:10.1007/978-3-030-02723-0_7 · Cited by 3 · see citing works
Sexual dysfunctions and metacognitive beliefs: a PRISMA-compliant systematic review
Olivari, C., Cugno, M. D., & Caselli, G. (2023) · Sexual & Relationship Therapy · doi:10.1080/14681994.2023.2253742 · Cited by 2 · see citing works
“These findings are in line with studies (e.g. Berner & Günzler, 2012) that showed the effectiveness of MJST in increasing sexual desire during treatment, but which was lost in the post-treatment period.”
Sajadian, A. S., Lahiji, M. R., Hashemi, E., Montazeri, A., Anbiaee, R., Omranipour, R., Nafissi, N., Heydari, L., Rasouli, M., Shishavan, N. G., et al. (2024) · Journal of Breast Disease · doi:10.61186/ijbd.17.2.26 · Cited by 2 · see citing works
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Evaluation and Treatment of Sexual Disorders Due to Medical Conditions
Steiner, A. J., & IsHak, W. W. (2017) · Springer eBooks · doi:10.1007/978-3-319-52539-6_22 · Cited by 2 · see citing works
Le « trouble » de l’éjaculation précoce : le critère d’une minute maximum de pénétration en question
Kempeneers, P., & Desseilles, M. (2014) · Sexologies · doi:10.1016/j.sexol.2014.06.005 · Cited by 2 · see citing works
Scientometric analysis of psychological interventions based upon the use of Hypnosis
Muñoz, M. A. (2017) · Revista Iberoamericana de Psicología · doi:10.33881/2027-1786.rip.9108 · Cited by 2 · see citing works
Psychosoziale Interventionen für sexuelle Funktionsstörungen bei Männern
Schmidt, H. M., Höhn, C., Widmeier, E., & Berner, M. M. (2017) · Zeitschrift für Sexualforschung · doi:10.1055/s-0043-109077 · Cited by 2 · see citing works
Seksuele disfuncties bij mannen
van Lankveld, J. J. D. M., de Boer, B.-J., & MEULEMAN, E. J. H. (2018) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-1111-8_17 · Cited by 2 · see citing works
Gatson, N. T., Milbourne, A. M., Ornelas, S., Nevel, K. S., & Boccia, M. L. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15663-2.00039-0 · Cited by 1 · see citing works
Syme, M. L., Graf, A. S., Cohn, T. J., & Cornelison, L. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818697-8.00017-0 · Cited by 1 · see citing works
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Sex Therapy: Brief Historic and Current Perspectives
de Lucena, B. B. (2017) · MOJ Women s Health · doi:10.15406/mojwh.2017.05.00134 · Cited by 1 · see citing works
“For women, the efficacy of cognitive-behavioral therapy has been reported in the treatment of all sexual dysfunctions [18].”
BackgroundInfluentialGeschiedenis van de seksuologie: paradigma’s, thema’s en debatten
Driel, M. V., Gijs, L. A. C. L., Laan, E. T. M., & van Lankveld, J. J. D. M. (2018) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-1111-8_2 · Cited by 1 · see citing works
Tratamiento de un caso de disfunción eréctil mediante terapia de pareja y terapia sexual
Aguayo, L. V., & Bernet, J. (2015) · Escritos de Psicología / Psychological Writings · doi:10.5231/psy.writ.2015.1806 · Cited by 2 · see citing works
Sex Therapy, Clinical Psychology of
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Connaughton, C., & McCabe, M. P. (2015) · Springer eBooks · doi:10.1007/978-981-287-080-3_5-1 · Cited by 1 · see citing works
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Sex, drugs, and women's desire
Nowogrodzki, A. (2015) · DSpace@MIT (Massachusetts Institute of Technology)
Female Sexual Function in Childhood, Adolescent, and Young Adult Cancer Survivors
Woodard, T. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-32973-4_5
Erectieproblemen (erectiele disfunctie)
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- Authors
- Berner, M., & Günzler, C.
- Affiliations
- University Medical Center Freiburg (DE)
- Corresponding author
- Berner, Michael
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-12-01
- Volume
- 9
- Issue
- 12
- Pages
- 3089-3107
- ISSN
- 1743-6095 (ISSN-L)
- 1743-6109
- OpenAlex
- W1902446911
- Cited by
- 100
- References
- 116
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 6 · 2022: 1 · 2021: 5 · 2020: 6 · 2019: 6 · 2018: 12 · 2017: 13 · 2016: 8 · 2015: 13 · 2014: 13 · 2013: 3 · 2012: 1
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- The Journal of Sexual Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- German Ministry for Education and Research (FKZ: 01 KG 0817)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Keywords
- male sexual dysfunction, psychosocial interventions, psychotherapy, female sexual dysfunction, premature ejaculation, cognitive behavioral therapy, Masters and Johnson, sildenafil, sexual function, treatment efficacy, methodological quality
- MeSH terms
- Sildenafil Citrate, Alprostadil, Counseling, Humans, Hypnosis, Injections, Male, Piperazines, Psychotherapy, Purines, Sexual Dysfunction, Physiological, Sulfones, Vasodilator Agents, Yohimbine, Randomized Controlled Trials as Topic, Couples Therapy, Phosphodiesterase 5 Inhibitors
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