Plasma noradrenaline correlates to sympathetic muscle nerve activity in normotensive man

WALLIN, B. GUNNAR; SUNDLÖF, GÖRAN; ERIKSSON, BRITT‐MARIE; DOMINIAK, PETER; GROBECKER, HORST; LINDBLAD, LARS ERIK

doi:10.1111/j.1748-1716.1981.tb06706.x

Cited by 316Cardiovascular and exercise physiologyBlood Pressure and Hypertension StudiesHeart Rate Variability and Autonomic Control

Plasma noradrenaline correlates to sympathetic muscle nerve activity in normotensive man

WALLIN, B. GUNNAR, SUNDLÖF, GÖRAN, ERIKSSON, BRITT‐MARIE, DOMINIAK, PETER, GROBECKER, HORST, LINDBLAD, LARS ERIK·1981·Acta Physiologica Scandinavica

DOI 10.1111/j.1748-1716.1981.tb06706.x

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Abstract

Recordings of multiunit sympathetic activity were made in muscle branches of the peroneal nerve in 22 healthy subjects at rest in recumbent position. Nerve activity was quantitated in terms of burst incidence (number of pulse synchronous sympathetic bursts per 100 heart beats or per min). In a separate session, 4-45 months later, blood was drawn from an antecubital vein for noradrenaline analysis. Both sympathetic activity and plasma concentrations of noradrenaline varied widely between subjects and both parameters increased with age. There was a significant positive correlation between a subject's level of sympathetic activity and his plasma concentration of noradrenaline. It is suggested that overflow of transmitter from sympathetic terminals in muscles contributes significantly to plasma levels of noradrenaline at rest.

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In general, muscle sympathetic nerve activity correlates well with the plasma norepinephrine concentration.
“in general, muscle sympathetic nerve activity correlates well with the plasma norepinephrine concentration (30, 31).”
From Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms. (1987) · cites this paper as [30]

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Authors: WALLIN, B. G., SUNDLÖF, G., ERIKSSON, B., DOMINIAK, P., GROBECKER, H., & LINDBLAD, L. E.
Affiliations: Uppsala University Hospital (SE)
University of Regensburg (DE)
Stockholm South General Hospital (SE)
ORCID: ERIKSSON, BRITT‐MARIE
Venue: Acta Physiologica Scandinavica
Publisher: Wiley
Published: 1981-01
Volume: 111
Issue: 1
Pages: 69-73
ISSN: 0001-6772 (ISSN-L)
1365-201X
DOI: 10.1111/j.1748-1716.1981.tb06706.x
OpenAlex: W2164088115
Cited by: 316
References: 23
Citations by year: 2025: 2 · 2024: 2 · 2023: 2 · 2022: 5 · 2021: 5 · 2020: 4 · 2019: 4 · 2018: 7 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 1 · 2013: 4 · 2012: 4
FWCI: 35.42
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 10203 d)
Locations: Acta Physiologica Scandinavica (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords: plasma norepinephrine, sympathetic activity, peroneal nerve, age-related changes, normotensive subjects, sympathetic nervous system
MeSH terms: Adult, Blood Pressure, Female, Humans, Male, Middle Aged, Muscles, Norepinephrine, Peroneal Nerve, Sympathetic Nervous System

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Plasma noradrenaline correlates to sympathetic muscle nerve activity in normotensive man

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