Cited by 473Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic DiseasesObesity, Physical Activity, Diet

Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US*

Open access
FORD, Earl S., LI, Chaoyang, ZHAO, Guixiang·2010·Journal of Diabetes

Abstract

Background: Recently, a Joint Scientific Statement bridged differences between previous definitions of metabolic syndrome. Our objective was to estimate the prevalence of metabolic syndrome in a representative sample of US adults and to examine its correlates. Methods: We analyzed data for up to 3461 participants aged ≥20 years of the 2003–2006 National Health and Nutrition Examination Survey. Results: Using waist circumference thresholds of ≥102 cm for men and ≥88 cm for women, the age‐adjusted prevalence of metabolic syndrome was 34.3% among all adults, 36.1% among men, and 32.4% among women. Using racial‐ or ethnic‐specific International Diabetes Federation criteria for waist circumference, the age‐adjusted prevalence of metabolic syndrome was 38.5% for all participants, 41.9% for men, and 35.0% for women. Prevalence increased with age, peaking among those aged 60–69 years. Prevalence was lower among African American men than White or Mexican American men, and lower among White women than among African American or Mexican American women. In a multivariate regression model, significant independent associations were noted for age (positive), gender (men higher than women), race or ethnicity (African Americans and participants of another race lower than Whites), educational status (inverse), hypercholesterolemia (positive), concentrations of C‐reactive protein (positive), leisure time physical activity (inverse), microalbuminuria (positive), and hyperinsulinemia (positive). Additional adjustment for body mass index weakened many of the associations, with educational status and microalbuminuria no longer significant contributors to the model. Conclusion: Metabolic syndrome continues to be highly prevalent among adults in the US.

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Authors
FORD, E. S., LI, C., & ZHAO, G.
Affiliations
Centers for Disease Control and Prevention (US)
Corresponding author
FORD, Earl S.
Venue
Journal of Diabetes
Publisher
Wiley
Published
2010-08-16
Volume
2
Issue
3
Pages
180-193
ISSN
  • 1753-0393 (ISSN-L)
  • 1753-0407
OpenAlex
W2136043682
Cited by
471
References
22
Citations by year
2026: 5 · 2025: 17 · 2024: 12 · 2023: 16 · 2022: 26 · 2021: 20 · 2020: 21 · 2019: 22 · 2018: 31 · 2017: 38 · 2016: 45 · 2015: 46 · 2014: 63 · 2013: 52 · 2012: 44
FWCI
26.06
Type
journal article
Language
en
Open access
Locations
  • Journal of Diabetes (publishedVersion, public-domain)
  • PubMed (publishedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, public-domain)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
metabolic syndrome, prevalence, sex differences, racial and ethnic differences, hypercholesterolemia, C-reactive protein, physical activity, microalbuminuria, hyperinsulinemia, educational attainment, body mass index
MeSH terms
Adult, Age Factors, Aged, Albuminuria, Blood Pressure, Cholesterol, Female, Humans, Hypoglycemic Agents, Insulin, Leisure Activities, Male, Middle Aged, Nutrition Surveys, Sex Characteristics, Triglycerides, United States, Exercise, Prevalence, Metabolic Syndrome, Racial Groups, Waist Circumference

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