Cited by 152Diabetes, Cardiovascular Risks, and LipoproteinsSex and Gender in HealthcareCardiovascular Disease and Adiposity

Metabolic syndrome: Does it differ between women and men?

Rochlani, Yogita, Pothineni, Naga Venkata, Mehta, Jawahar L.·2015·Cardiovascular Drugs and Therapy

Abstract

Cardiovascular disease represents a massive healthcare burden worldwide. Gender differences in the pathophysiology, presentation and prognosis of cardiovascular disease have been described in the literature. Metabolic syndrome, characterized by a cluster of metabolic abnormalities is associated with increased risk for type 2 diabetes mellitus and atherosclerotic cardiovascular disease. With the global obesity epidemic, the prevalence of metabolic syndrome is rising rapidly in the developed as well as developing world. However, there is considerable variation in the prevalence based on geography, age, sex and, definition used for diagnosis. Data on gender related differences in metabolic syndrome is relatively scarce. Here, we aim to review the gender differences in epidemiology and pathophysiology of metabolic syndrome as well as its individual components. Knowledge of gender differences in metabolic syndrome can help design gender specific preventative and therapeutic strategies that will have a positive impact on overall population health.

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Crossref · 10.1007/s10557-015-6593-6

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93 of 93 references verified0 citation errors · 0 not checkable

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Authors
Rochlani, Y., Pothineni, N. V., & Mehta, J. L.
Affiliations
University of Arkansas for Medical Sciences (US)
Corresponding author
Rochlani, Yogita
Venue
Cardiovascular Drugs and Therapy
Published
2015-05-21
Volume
29
Issue
4
Pages
329-338
ISSN
  • 0920-3206 (ISSN-L)
  • 1573-7241
OpenAlex
W329676011
Cited by
152
References
94
Citations by year
2026: 4 · 2025: 12 · 2024: 13 · 2023: 14 · 2022: 19 · 2021: 19 · 2020: 18 · 2019: 10 · 2018: 12 · 2017: 16 · 2016: 13 · 2015: 2
FWCI
12.40
Type
journal article
Language
en
Open access
closed
Locations
  • Cardiovascular Drugs and Therapy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords
metabolic syndrome, sex differences, gender differences, cardiovascular disease, type 2 diabetes, atherosclerotic cardiovascular disease, obesity, pathophysiology
MeSH terms
Animals, Female, Hormones, Humans, Male, Polycystic Ovary Syndrome, Sex Characteristics, Metabolic Syndrome

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