Cited by 607Diet, Metabolism, and DiseaseRegulation of Appetite and ObesityBiochemical Analysis and Sensing Techniques

The DOI matches its Crossref record; 226 of the 230 references it cites were found in a registry or an index.

Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism.

Open access

Havel, Peter J.·2005·Nutrition Reviews

DOI 10.1111/j.1753-4887.2005.tb00132.x

Open this paper in CoChat — free account Open PDF

Abstract

Fructose intake and the prevalence of obesity have both increased over the past two to three decades. Compared with glucose, the hepatic metabolism of fructose favors lipogenesis, which may contribute to hyperlipidemia and obesity. Fructose does not increase insulin and leptin or suppress ghrelin, which suggests an endocrine mechanism by which it induces a positive energy balance. This review examines the available data on the effects of dietary fructose on energy homeostasis and lipid/carbohydrate metabolism. Recent publications, studies in human subjects, and areas in which additional research is needed are emphasized.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/j.1753-4887.2005.tb00132.x

Cites

226 of 226 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Ghrelin is a growth-hormone-releasing acylated peptide from stomach
Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H., & Kangawa, K. (1999) · Nature · doi:10.1038/45230 · Cited by 8,479
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and Amino Acids
Trumbo, P., Schlicker, S., Yates, A. A., & Poos, M. (2002) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(02)90346-9 · Cited by 5,993
Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.
Hedley, A. A., Ogden, C., Johnson, C. L., Carroll, M., Curtin, L. R., & Flegal, K. (2004) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.291.23.2847 · Cited by 4,670
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., Fei, H., Kim, S., Lallone, R., Ranganathan, S., et al. (1995) · Nature Medicine · doi:10.1038/nm1195-1155 · Cited by 3,725
Congenital leptin deficiency is associated with severe early-onset obesity in humans
Montague, C. T., Farooqi, I. S., Whitehead, J. P., Soos, M. A., Rau, H., Wareham, N. J., Sewter, C. P., Digby, J. E., Mohammed, S. N., Hurst, J. A., et al. (1997) · Nature · doi:10.1038/43185 · Cited by 2,936
Ghrelin enhances appetite and increases food intake in humans
Wren, A. M., Seal, L. J., Cohen, M. A., Brynes, A. E., Frost, G. S., Murphy, K. G., Dhillo, W. S., Ghatei, M. A., & Bloom, S. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.12.8111 · Cited by 2,494
Gut hormone PYY3-36 physiologically inhibits food intake
Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., et al. (2002) · Nature · doi:10.1038/nature00887 · Cited by 2,351
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
Clément, K., Vaisse, C., Lahlou, N., Cabrol, S., Pelloux, V., Cassuto, D., Gourmelen, M., Dina, C., Chambaz, J., Lacorte, J.-M., et al. (1998) · Nature · doi:10.1038/32911 · Cited by 2,346
Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery
Cummings, D. E., Weigle, D. S., Frayo, R. S., Breen, P. A., Marina, K., Dellinger, E. P., & Purnell, J. Q. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012908 · Cited by 2,271

Show all 230 references

Research works printed but not linked: 8

Havel, 2003, Pituitary and Periphery: Communication In and Out, 89
Bowman, 1999, Diets of individuals based on energy intakes from added sugars, Fam Econ Nutr Rev, 12, 31
Schwarz, 1993, De novo lipogenesis during fasting and oral fructose ingestion in lean and obese hyperinsuline-mic subjects, Diabetes, 42, A39
Havel, 2003, Short-term and long-term consumption of high fructose, but not high glucose, diets increases postprandial triglyc-erides and apo-lipoprotein-B in women, J Invest Med, 51, S163
Schwarz, 1993, Effect of oral fructose on lipolysis, fat oxidation, fractional and absolute de novo lipogenesis (DNL) using mass isotopomer distribution analysis (MIDA), FASEB J, 7, A867
Schwarz, 1994, Effect of fructose ingestion on glucose production (GP) and de novo lipogenesis (DNL) in normal and hyperinsulinemic obese humans, Diabetes, 43, A52
Moore, 2000, Fructose decreases the glucose and insulin responses to an oral glucose tolerance test (OGTT) in individuals with type 2 diabetes (DM2), Diabetes, 49, A84
Havel, 2002, Consuming high fructose meals reduces 24 hour circulating insulin and leptin concentrations and does not suppress circulating ghrelin in women, J Invest Med, 50, 26A

Sorted by citations

Items 401–500 of 605

Occurrence of Inborn Errors of Metabolism in Newborns, Diagnosis and Prophylaxis
Bharadwaj, A., Wahi, N., & Saxena, A. (2020) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530321666201223110918 · Cited by 8
Metabolic and Blood Pressure Effects of Consuming Two Kiwifruit Daily for 7 Weeks: A Randomised Controlled Trial
Monro, J. A., Lubransky, A. C., Mishra, S. S., Haszard, J. J., & Venn, B. J. (2022) · Nutrients · doi:10.3390/nu14132678 · Cited by 9
Low-calcium diet prevents fructose-induced hyperinsulinemia and ameliorates the response to glucose load in rats
Voznesenskaya, A., & Tordoff, M. G. (2015) · Nutrition & Metabolism · doi:10.1186/s12986-015-0035-0 · Cited by 8
Carbohydrate metabolic pathway genes associated with quantitative trait loci (QTL) for obesity and type 2 diabetes: Identification by data mining
Varma, V., Wise, C., & Kaput, J. (2010) · Biotechnology Journal · doi:10.1002/biot.201000067 · Cited by 8
The development of obesity and prediabetes under conditions of long-term consumption of fructose solution in rats
Konopelnyuk, V. V., Yurchenko, A., Karpovets, T. P., & Остапченко, Л. І. (2015) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2015.50101 · Cited by 8
Understanding the Impact of Added Sugar Consumption on Risk for Type 2 Diabetes
Price, C. A., & Stanhope, K. L. (2016) · Journal of the California Dental Association · doi:10.1080/19424396.2016.12221068 · Cited by 9
Effect of dietary fructose on lipid metabolism, body weight and glucose tolerance in humans
Vasankari, T. J., & Vasankari, T. (2006) · Food & Nutrition Research · doi:10.3402/fnr.v50i2.1559 · Cited by 8
Relationship between Total Sugar Intake and Obesity Indices in Female Collegians
Lee, Y., Bae, Y., Kim, E. Y., Yeon, J., Kim, M.-H., Kim, M., Lee, J., & Cho, H. (2012) · Journal of Nutrition and Health · doi:10.4163/kjn.2012.45.1.57 · Cited by 7
Cardiovascular effects of high-fructose intake in rats with nitric oxide deficiency
Zemančíková, A., & Török, J. (2014) · Interdisciplinary Toxicology · doi:10.2478/intox-2014-0022 · Cited by 7
Sugar and nutritional extremism
Belkova, J., Rozkot, M., Danek, P., Klein, P., Matonohová, J., & Podhorna, I. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.940027 · Cited by 7
Effects of long-term consumption of high fructose corn syrup containing peach nectar on body weight gain in sprague dawley rats
Sinir, G. Ö., Suna, S., İnan, S., Bağdaş, D., Tamer, C. E., Çopur, Ö. U., Sığırlı, D., Sarandöl, E., Sönmez, G., Ercan, İ., et al. (2016) · Food Science and Technology · doi:10.1590/1678-457x.25416 · Cited by 7
Lasting metabolic effect of a high-fructose diet on global cerebral ischemia
Ojo, O. P., Perez-Corredor, P. A., Vargas, J. A. G., Akinola, O. B., & Cardona‐Gómez, G. P. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1841482 · Cited by 7
Dietary carbohydrate sources influence the growth performance, plasma biochemical parameters and expression of genes involved in glucose metabolism in juvenile Pelodiscus sinensis
Ren, T., Liu, H., Zhang, X., Zhang, P., Gao, Q., Jia, X., Xu, T., Yue, T., & Yang, Z. (2021) · Aquaculture Reports · doi:10.1016/j.aqrep.2021.100718 · Cited by 7
Cardiovascular Disease Mortality
Ross, S. M. (2014) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000066 · Cited by 10
How the chemical features of molecules may have addressed the settlement of metabolic steps
CORSO, A. D., Cappiello, M., Moschini, R., Balestri, F., & Mura, U. (2017) · Metabolomics · doi:10.1007/s11306-017-1300-1 · Cited by 7
Fructose and High-Fructose Corn Syrup
Keim, N. L., Stanhope, K. L., & Havel, P. J. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-384947-2.00333-0 · Cited by 7
Self-citation
Vascular Biology Protocols
(2007) · Methods in molecular medicine · doi:10.1007/978-1-59745-571-8 · Cited by 6
Efectos del consumo elevado de fructosa y sacarosa sobre parámetros metabólicos en ratas obesas y diabéticas
María Catalina Olguin, B., Posadas, M., Revelant, G. C., Labourdette, V., Marinozzi, D., María Rosa Venezia, N., & Zingale, M. I. (2015) · Revista chilena de nutrición · doi:10.4067/s0717-75182015000200006 · Cited by 6
Effect of a high-fructose diet on glucose tolerance, plasma lipid and hemorheological parameters during oral contraceptive administration in female rats
Olatunji, L. A., Oyeyipo, I. P., & Usman, T. O. (2013) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-2012-1561 · Cited by 6
Challenges of childhood obesity in a developing economy: A review
Eke, C., Ubesie, A., & Ibe, B. C. (1970) · Nigerian Journal of Paediatrics · doi:10.4314/njp.v42i3.1 · Cited by 6
The New Zealand sugar (fructose) fountain: time to turn the tide?
Thornley, S., McRobbie, H. J., & Jackson, G. L. (2010) · PubMed · Cited by 6
Glucose transporter 8 immunoreactivity in astrocytic and microglial cells in subependymal areas of human brains
Mashima, M., Chiba, Y., Murakami, R., Uemura, N., Matsumoto, K., Kawauchi, M., Kanenishi, K., Hata, T., & Ueno, M. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.11.005 · Cited by 6
Fruit makes you fat?
Weichselbaum, E. (2008) · Nutrition Bulletin · doi:10.1111/j.1467-3010.2008.00725.x · Cited by 6
Comparative analysis of glucose and fructose tolerance in two marine fishes: effects on insulin secretion and acute hypoxia tolerance
Ma, Q., Xu, H., Limbu, S. M., Wei, Y., & Liang, M. (2023) · Frontiers in Marine Science · doi:10.3389/fmars.2023.1310415 · Cited by 6
Toxins, Malnutrition, Stress, Infections and Electromagnetic Pollution: Looking about New Perspectives in Development of Diseases
Peres, H. A., Pereira, L. R. L., & Foss, M. C. F. (2016) · Journal of Nutrition & Food Sciences · doi:10.4172/2155-9600.1000558 · Cited by 5
Nutrition and Ovulatory Function
Chavarro, J. E., Gaskins, A. J., & Afeiche, M. C. (2015) · CRC Press eBooks · doi:10.1201/b18190-2 · Cited by 5
Dysregulation of mitochondrial dynamics mediated aortic perivascular adipose tissue-associated vascular reactivity impairment under excessive fructose intake
Wu, K. L. H., Wu, C., Chen, L.-W., Chang, H., Cheng, C., Wu, C.-Y., Lee, Y., Chen, I., Hung, C., & Liu, W. (2024) · Nutrition & Metabolism · doi:10.1186/s12986-023-00776-7 · Cited by 5
Lactiplantibacillus plantarum dfa1 reduces obesity caused by a high carbohydrate diet by modulating inflammation and gut microbiota
Ondee, T., Pongpirul, K., Wongsaroj, L., Senaprom, S., Wattanaphansak, S., & Leelahavanichkul, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-10435-x · Cited by 8
Synthesis, spectroscopic and crystal structure of a new 2D coordination polymer of Ni(II) constructed by naphthalene-1,4-dicarboxylic acid; Nanomolar detection of fructose at a nano-structured Ni(II) coordination polymer multiwall carbon nanotube
Derikvand, Z., Azadbakht, A., Olmstead, M. M., Karimi, Z., & Gharamaleki, J. A. (2015) · Journal of the Iranian Chemical Society · doi:10.1007/s13738-015-0766-x · Cited by 5
Tissue Changes in the Development of Fatty Liver by Chronic Ingestion of Sucrose Associated with Obesity and Dyslipidemia in Rats
Solano-Silva, M., Santillana, I. B.-D., Soto-Rodríguez, I., Bautista-Piña, C., & Alexander-Aguilera, A. (2018) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000247 · Cited by 5
Silencing of GPR82 with Interference RNA Improved Metabolic Profiles in Rats with High Fructose Intake
Romero‐Nava, R., Aguayo-Cerón, K. A., Ruíz-Hernández, A., Huang, F., Hong, E., Aguilera‐Méndez, A., & Villafaña, S. (2019) · Journal of Vascular Research · doi:10.1159/000500781 · Cited by 5
Obesity Development and Signs of Metabolic Abnormalities in Young Göttingen Minipigs Consuming Energy Dense Diets Varying in Carbohydrate Quality
Curtasu, M. V., Hedemann, M. S., Lærke, H. N., & Knudsen, K. E. B. (2021) · Nutrients · doi:10.3390/nu13051560 · Cited by 7
Association of Sugar-Sweetened Beverages Consumption and Hypertension in Korean Adults: Korean National Health and Nutrition Examination Survey 2012–2013
Hwang, E., Yoo, J., Shin, J., Bae, M.-J., & Jo, S.-I. (2016) · Korean Journal of Family Practice · doi:10.21215/kjfp.2016.6.5.446 · Cited by 5
Molecular alterations induced by fructose and its impact on metabolic diseases
Loza-Medrano, S. S., Baiza-Gutman, L. A., Ibáñez-Hernández, M. Á., Cruz, M., & Díaz-Flores, M. (2019) · PubMed · Cited by 5
Nutrition Diagnostic Analysis for Nutrition Care Process Model in Adults of a Health Screening & Promotion Center
Lee, H. S., Chang, J. H., Lee, H. J., Park, S. J., & Kang, E. H. (2015) · 대한지역사회영양학회지 · doi:10.5720/kjcn.2015.20.1.61 · Cited by 5
Gas Chromatography with Flame-Ionization Detection-Based Analysis of Sugar Contents in Korean Agricultural Products for Patients with Galactosemia
Jeong, H.-N., Kwon, R. H., Kim, Y., Yoo, S., Yoo, S. M., & Wee, C.-D. (2023) · Foods · doi:10.3390/foods12051104 · Cited by 4
Approaches to nutritional research using organoids; fructose treatment induces epigenetic changes in liver organoids
Yamazaki, M., Yamada, H., Munetsuna, E., Ando, Y., Mizuno, G., Teshigawara, A., Ichikawa, H., Nouchi, Y., Kageyama, I., Wakasugi, T., et al. (2024) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2024.109671 · Cited by 4
The expression and activity of antioxidant enzymes in the liver of rats exposed to high‐fructose diet in the period from weaning to adulthood
Glban, A. M., Teofilović, A., Veličković, N. A., Nikolić‐Kokić, A., Blagojević, D. P., Matić, G. M., & Brkljačić, J. M. (2014) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6953 · Cited by 4
The effect of high-fructose corn syrup vs. sucrose on anthropometric and metabolic parameters: A systematic review and meta-analysis
Li, X., Luan, Y., Li, Y., Ye, S., Wang, G., Cai, X., Liang, Y., Kord‐Varkaneh, H., & Luan, Y. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1013310 · Cited by 4
Weak Association between Sweeteners or Sweetened Beverages and Diabetes
White, J. S. (2008) · Journal of Nutrition · doi:10.1093/jn/138.1.138 · Cited by 4
Immobilization of nickel-dipicolinic acid onto a glassy carbon electrode modified with bimetallic Au-Pt inorganic-organic hybrid nanocomposite: Application to micromolar detection of fructose
Gholivand, M. B., & Azadbakht, A. (2012) · Russian Journal of Electrochemistry · doi:10.1134/s1023193512040064 · Cited by 4
Fructose potentiates the protective efficiency of live Edwardsiella tarda cell vaccine
Wang, C., Peng, X., & Li, H. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1170166 · Cited by 4
Fructose Metabolism and Health Risks
Abike, R. R. (2015) · Journal of Obesity & Weight loss Therapy · doi:10.4172/2165-7904.1000245 · Cited by 4
Case Report: Management of a Patient With Chylomicronemia Syndrome During Pregnancy With Medical Nutrition Therapy
Zahedi, M., Asghari, G., Mirmiran, P., & Hosseinpanah, F. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.602938 · Cited by 4
Induction of Metabolic Syndrome by Excess Fructose Consumption
Wong, W.-Y., & Brown, L. (2013) · Springer eBooks · doi:10.1007/978-1-4614-9317-4_3 · Cited by 4
Dietary Patterns and Insulin Resistance
Torsoni, A. S., Milanski, M., & Torsoni, M. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801585-8.00002-6 · Cited by 4
Sweeteners and health: findings from recent research and their impact on obesity and related metabolic conditions
Rippe, J. M., & Tappy, L. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.7 · Cited by 4
Dietary Management of Nonalcoholic Fatty Liver Disease (NAFLD) by n-3 Polyunsaturated Fatty Acid (PUFA) Supplementation
Jeyakumar, S., & Vajreswari, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814466-4.00030-6 · Cited by 4
Fructose‐Derived Endogenous Toxins
O'Brien, P. J., Feng, C., Lee, O., Dong, Q., Mehta, R., Bruce, J., & Bruce, W. R. (2009) · doi:10.1002/9783527628100.ch7 · Cited by 4
A process systems Engineering approach to analysis of fructose consumption in the liver system and consequences for Non-Alcoholic fatty liver disease
Liao, Y., Davies, N. A., & Bogle, I. D. L. (2022) · Chemical Engineering Science · doi:10.1016/j.ces.2022.118131 · Cited by 3
Exploring the sugar-sweetened beverage tax (SSBT) pass-through rate in the Irish hospitality sector
Houghton, F. T., Stritch, J. M., Auerbach, J., Daly, M., & Houghton, D. (2024) · BMC Public Health · doi:10.1186/s12889-024-19891-y · Cited by 3
The Protective Effect of Boric Acid Against High Fructose-Induced Liver and Kidney Damage in Rats
Yüksel, D., Başeğmez, M., & Kan, F. (2025) · Biological Trace Element Research · doi:10.1007/s12011-025-04542-z · Cited by 3
Evaluation of Ireland’s Sugar-Sweetened Beverage Tax (SSBT)
Houghton, F. T., Stritch, J. M., Auerbach, J., Houghton, D., & Daly, M. (2025) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-025-03906-7 · Cited by 3
Probiotics to Treat Visceral Obesity and Related Liver Disease
Vajro, P., Poeta, M., Pierri, L., Pizza, C., D’Aniello, R., Sangermano, M., Massa, G., & Paolella, G. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-407869-7.00033-7 · Cited by 3
The total sugar and free sugar content in beverages categorized according to recipes at coffee and beverage stores
Yeon, J., Lee, S. K., Shin, K.-Y., Kwon, K., Lee, W. Y., Kang, B.-W., & Park, H. (2013) · Journal of Nutrition and Health · doi:10.4163/jnh.2013.46.4.382 · Cited by 3
The time has come to flag and reduce excess fructose intake
Brinton, E. A. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.040 · Cited by 3
Sugar: The Bitter Truth
Glynn, J. (2016) · Journal of Nutritional Health & Food Engineering · doi:10.15406/jnhfe.2016.04.00148 · Cited by 3
The main approaches to dietary changes in non-alcoholic fatty liver disease
Drapkina, O. M., Шепель, Р. Н., Starodubova, A. V., & Evsutina, Y. V. (2018) · Russian Journal of Preventive Medicine · doi:10.17116/profmed20182106178 · Cited by 3
Farklı Miktarlarda Tüketilen Fruktozun, Vücut Ağırlığı ve Bazı Biyokimyasal Parametreler Üzerine Etkisi
Köseler, E., & Kızıltan, G. (2019) · Journal of Nutrition and Dietetics · doi:10.33076/2019.bdd.1196 · Cited by 3
The consequences of poor dietary patterns on the proliferation of non-alcoholic fatty liver disease
Ahmed, A., Maham, K., Afzaal, M., Saleem, M. A., Nadeem, M., Saeed, F., Hussain, M., & Jbawi, E. M. A. (2024) · Cogent Food & Agriculture · doi:10.1080/23311932.2024.2325206 · Cited by 4
Association between different dietary carbohydrates and risk of gallstone: a case-control study in Iranian adults
Nilghaz, M., Shahparvari, M., Hekmatdoost, A., Saadati, S., Ghorbani, M., Sadeghi, A., & Yari, Z. (2024) · Nutrition & Food Science · doi:10.1108/nfs-12-2023-0299 · Cited by 3
Computational modelling in liver system and liver disease
Liao, Y., Davies, N. A., & Bogle, I. D. L. (2025) · Physical Sciences Reviews · doi:10.1515/psr-2024-0051 · Cited by 3
Metabolism and satiety
Rodrı́guez, A., Catalán, V., & Frühbeck, G. (2013) · Elsevier eBooks · doi:10.1533/9780857098719.2.75 · Cited by 3
Hepatic Lipogenesis: Nutritional Control and Pathophysiological Relevance
Woo, S., Guo, T., & Wu, C. (2015) · Springer eBooks · doi:10.1007/978-3-319-25065-6_10 · Cited by 3
Sugar Contents Analysis of Retort Foods
Jeong, D.-U., Im, J. S., Kim, C.-H., Kim, Y.-K., Park, Y., Jeong, Y., & Om, A. (2015) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2015.44.11.1666 · Cited by 3
Metabolic effects of excessive consumption of fructose
Okręglicka, K., Pardecki, M., Jagielska, A. M., & Tyszko, P. Z. (2017) · Medycyna Ogólna i Nauki o Zdrowiu · doi:10.26444/monz/76690 · Cited by 3
Fructose; a Hidden Threat for Chronic Diseases -
Korkmaz, A., & Korkmaz (2008) · TAF Preventive Medicine Bulletin · Cited by 7
Glucose- and Fructose-Induced Toxicity in the Liver and Brain
Farooqui, A. A. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7318-3_2 · Cited by 3
Do favourable effects of increasing unsaturated fat intake on cardiovascular disease risk outweigh the potential adverse effect on body weight?
Zock, P. L. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803486 · Cited by 3
Respostas metabólicas à suplementação com frutose em exercício de força de membros inferiores
Sá, C. A. D., Fernández, J. M., & Silva‐Grigoletto, M. E. D. (2010) · Revista Brasileira de Medicina do Esporte · doi:10.1590/s1517-86922010000300004 · Cited by 3
Are soft drink consumption and fatty liver in any way connected
Hofmeister, C., Haenle, M. M., Akinli, A. S., Boehm, B. O., Mason, R. A., & Kratzer, W. (2013) · Cited by 3
Nutritional and Metabolic Characteristics of High Fructose Corn Syrup and Its Effects on Health
Kim, H., Jeong, J., & Go, G. (2015) · Food Engineering Progress · doi:10.13050/foodengprog.2015.19.2.87 · Cited by 3
Childhood Overweight: Parental Perceptions and Readiness for Change
Howard, K. R. (2015) · Journal of Near Infrared Spectroscopy · doi:10.1177/096703350702300201 · Cited by 3
Climatological Nephropathy: An Overview
Jaswal, P., Sharma, P., & Basu, J. (2021) · International Journal of Health Sciences and Research · doi:10.52403/ijhsr.20210913 · Cited by 3
Fructose Metabolism and Acute Myeloid Leukemia
Kansal, R. (2021) · Exploratory Research and Hypothesis in Medicine · doi:10.14218/erhm.2021.00042 · Cited by 3
Rat Models of Cardiac Insulin Resistance
Ghosh, S., Rodrigues, B. B., & Ren, J. T. (2007) · Methods in molecular medicine · doi:10.1007/978-1-59745-571-8_7 · Cited by 3
Relationship between daily dietary fructose intake, body composition and biochemical parameters patients with type 2 diabetes
Arslan, S., & Şanlıer, N. (2016) · Journal of Human Sciences · doi:10.14687/jhs.v13i2.3737 · Cited by 3
Sugar-Sweetened Beverages Consumption and Long-Term Side Effects on Nutrition and Health Outcomes in Pediatric Age Group
Heidari‐Beni, M., Rafie, N., Akbarian, S.-A., & Kelishadi, R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816687-1.00008-4 · Cited by 2
Neurochemical Effects of Western Diet Consumption on Human Brain
Farooqui, A. A., & Farooqui, T. (2015) · Wiley eBooks · doi:10.1002/9781118840634.ch2 · Cited by 3
Effects of Natural Products on Sugar Metabolism and Digestive Enzymes
Aydın, E. (2015) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York) · Cited by 3
Medical Journal Watch: Context and Applications
Challem, J. (2009) · Alternative and Complementary Therapies · doi:10.1089/act.2009.15204 · Cited by 3
Journal of Diabetes and Obesity
Castonguay, T. W., Campbell, E. S., & Internationals, O. (2019) · Journal of Diabetes and Obesity · doi:10.15436/2376-0494.14.004 · Cited by 3
Impact of Kiwifruit Consumption on Cholesterol Metabolism in Rat Liver: A Gene Expression Analysis in Induced Hypercholesterolemia
Gorji, A. E., Ciecierska, A., Leontowicz, H., Roudbari, Z., & Sadkowski, T. (2024) · Nutrients · doi:10.3390/nu16233999 · Cited by 3
Obesity: Nature or Nurture?
Lustig, R. H. (2010) · Endocrine updates · doi:10.1007/978-1-4419-7034-3_1 · Cited by 2
Added Sugars and Health: What Do We Really Know?
Rippe, J. M., & Angelopoulos, T. J. (2016) · Springer eBooks · doi:10.1007/978-3-319-43027-0_20 · Cited by 2
Effects of High‐Fructose Corn Syrup Addition to Broiler Diets on Performance, Carcass Yield, Visceral Weights, Gut pH and Some Blood Parameters
Şen, G., Demirci, M., Evci, Ş., Şenol, A., & Karslı, M. A. (2024) · Veterinary Medicine and Science · doi:10.1002/vms3.70058 · Cited by 2
Influence of Diet on Endothelial Dysfunction
Lottenberg, A. M., Lavrador, M. S. F., Afonso, M. S., & Machado, R. M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812348-5.00024-6 · Cited by 2
Glycaemic control, insulin resistance and obesity
Herter‐Aeberli, I., & Zimmermann, M. B. (2007) · Elsevier eBooks · doi:10.1533/9781845693114.1.43 · Cited by 2
Contribution of Dietary Carbohydrates in Induction of Oxidative Stress
Farooqui, A. A. (2014) · Springer eBooks · doi:10.1007/978-3-319-04111-7_8 · Cited by 2
Fructose Consumption and Moderate Zinc Deficiency Influence Growth and Adipocyte Metabolism in Young Rats Prone to Adult-Onset Obesity
Streiff, E. L., Stanhope, K. L., Graham, J. L., Havel, P. J., & King, J. C. (2007) · Biological Trace Element Research · doi:10.1007/s12011-007-0012-1 · Cited by 2
Self-citation
Neurochemical Effects of Long Term Consumption of Simple Carbohydrates
Farooqui, A. A. (2015) · Springer eBooks · doi:10.1007/978-3-319-15254-7_3 · Cited by 2
Implicaciones metabólicas del consumo excesivo de fructosa
Solís, V. E., Gómez, G., & Gómez, G. (2009) · Acta Médica Costarricense · doi:10.51481/amc.v49i4.461 · Cited by 2
Role of Sugar Intake in Beverages on Overweight and Health
Lafontan, M. (2010) · Nutrition Today · doi:10.1097/nt.0b013e3181fe419e · Cited by 2
ACIDO URICO ¿UN NUEVO FACTOR CONTRIBUYENTE AL DESARROLLO DE OBESIDAD?
Alex Valenzuela, M. (2016) · Revista chilena de nutrición · doi:10.4067/s0717-75182016000300011 · Cited by 2
Impact of the Association of a High Fructose Diet and Chronic Mild Stress on Metabolic and Affective Disorders in Male Rat
Chahirou, Y., Lamtai, M., Mesfioui, A., Ouichou, A., Coulibaly, M., Boussekkour, R., & Hessni, A. E. (2018) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2018.84010 · Cited by 2
Rice Bran Oil Ameliorates Hepatic Insulin Resistance in Fructose Fed-Rats
Ahmed, M. A., Ali, N. A., Elbast, S. A. A., & Mohamed, M. A. (2018) · The Egyptian Journal of Hospital Medicine · Cited by 2
Impairment of HDL by Pollutants
Cho, K. (2019) · Springer eBooks · doi:10.1007/978-981-13-7387-9_4 · Cited by 2
Cholesterotropic and cuprotropic chemicals
Klevay, L. M. (2020) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.10426 · Cited by 2
Effects and Issues of Diet Fat on Cardiovascular Metabolism
Nishikawa, Y. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.93261 · Cited by 2
Authors' Response
Lustig, R. H., & Schwarz, J. (2011) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.12.003 · Cited by 2

Authors: Havel, P. J.
Affiliations: University of California, Davis (US)
Corresponding author: Havel, Peter J.
ORCID: Havel, Peter J.
Venue: Nutrition Reviews
Publisher: Oxford University Press (OUP)
Published: 2005-05
Volume: 63
Issue: 5
Pages: 133-157
ISSN: 0029-6643 (ISSN-L)
1753-4887
DOI: 10.1111/j.1753-4887.2005.tb00132.x
OpenAlex: W2162627097
Cited by: 607
References: 230
Citations by year: 2026: 5 · 2025: 11 · 2024: 13 · 2023: 13 · 2022: 14 · 2021: 21 · 2020: 20 · 2019: 28 · 2018: 32 · 2017: 23 · 2016: 46 · 2015: 54 · 2014: 42 · 2013: 48 · 2012: 37
FWCI: 15.31
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Nutrition Reviews (publishedVersion)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: American Diabetes Association
U.S. Department of Agriculture
Dairy Management
National Institutes of Health (5r01hl075675-05, 58108, HL‐075675)
National Heart, Lung, and Blood Institute (HL 075675, R01 HL-091333, R01HL107256)
National Institute of Diabetes and Digestive and Kidney Diseases (R03DK058108, DK-58108)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
Keywords: dietary fructose, energy homeostasis, lipid metabolism, carbohydrate metabolism, obesity, hepatic lipogenesis, hyperlipidemia, insulin, leptin, ghrelin, energy balance
MeSH terms: Beverages, Diabetes Mellitus, Type 2, Energy Metabolism, Fructose, Glucose, Humans, Hyperlipidemias, Insulin, Insulin Resistance, Obesity, Leptin, Peptide Hormones, Ghrelin

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks