The DOI matches its Crossref record; 174 of the 175 references it cites were found in a registry or an index; none of the 168 sources its claims cite is checked for support yet.
Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosis
Open accessAbstract
Diarrhea is best defined as passage of loose stools often with more frequent bowel movements. For clinical purposes, the B ristol S tool F orm S cale works well to distinguish stool form and to identify loose stools. Laboratory testing of stool consistency has lagged behind. Acute diarrhea is likely to be due to infection and to be self‐limited. As diarrhea becomes chronic, it is less likely to be due to infection; duration of 1 month seems to work well as a cut‐off for chronic diarrhea, but detailed scientific knowledge is missing about the utility of this definition. In addition to duration of diarrhea, classifications by presenting scenario, by pathophysiology, and by stool characteristics (e.g. watery, fatty, or inflammatory) may help the canny clinician refine the differential diagnosis of chronic diarrhea. In this regard, a careful history remains the essential part of the evaluation of a patient with diarrhea. Imaging the intestine with endoscopy and radiographic techniques is useful, and biopsy of the small intestine and colon for histological assessment provides key diagnostic information. Endomicroscopy and molecular pathology are only now being explored for the diagnosis of chronic diarrhea. Interest in the microbiome of the gut is increasing; aside from a handful of well‐described infections because of pathogens, little is known about alterations in the microbiome in chronic diarrhea. Serological tests have well‐defined roles in the diagnosis of celiac disease but have less clearly defined application in autoimmune enteropathies and inflammatory bowel disease. Measurement of peptide hormones is of value in the diagnosis and management of endocrine tumors causing diarrhea, but these are so rare that these tests are of little value in screening because there will be many more false‐positives than true‐positive results. Chemical analysis of stools is of use in classifying chronic diarrhea and may limit the differential diagnosis that must be considered, but interpretation of the results is still evolving. Breath tests for assessment of carbohydrate malabsorption, small bowel bacterial overgrowth, and intestinal transit are fraught with technical limitations that decrease sensitivity and specificity. Likewise, tests of bile acid malabsorption have had limited utility beyond empirical trials of bile acid sequestrants.
Overview
CoChat Summary
TL;DR
This working party report reviews definitions, classification, and diagnostic evaluation of chronic diarrhea, concluding that a 4-week duration cutoff is arbitrary and that careful history plus targeted testing remains central. It surveys classification by pathophysiology and stool characteristics and assesses stool, serologic, breath, bile acid, pancreatic, imaging, endoscopic, and biopsy tests, highlighting gaps and limited utility of many tests.
Key findings
- Chronic diarrhea is less frequent than acute diarrhea; 3–5% of the population may have diarrhea lasting more than 1 month in any given year. Normal stool output averages approximately 100 g/day, with an upper 95% confidence limit of roughly 200 g/day, though up to 300 g may be normal on a high-fiber diet; about 20% of patients referred to one tertiary center for chronic diarrhea had normal stool weight.
- IBS and functional diarrhea are the most common causes of chronic diarrhea in Western populations. IBS onset averaged 38 ± 14 years in one large study, while microscopic colitis averaged 57 ± 13 years; IBS shows a female predominance with a sex ratio of 3:1 in primary care consulters. Microscopic colitis accounted for 10% of chronic diarrhea cases in patients over 70 years in Sweden.
- Fecal osmotic gap helps classify watery diarrhea: a gap < 50 mOsm/kg is characteristic of secretory diarrhea, and a gap > 75 mOsm/kg is characteristic of osmotic diarrhea.
- Breath test performance is variable: glucose hydrogen breath tests for small intestinal bacterial overgrowth had reported sensitivity 27–93% and specificity 30–86%, while lactulose hydrogen breath tests had sensitivity 17–89% and specificity 44–100%. Capsule endoscopy retention occurred in 1.3% of patients in one retrospective Swedish study and may be as high as 13% in known Crohn’s disease.
Methods
- Design: Working party report/consensus review from the Gastro 2013 APDW/WCOG Shanghai Working Party, proposed by the American College of Gastroenterology to the World Gastroenterology Organisation, to examine definitions, classification, and diagnosis of chronic diarrhea.
- Data and analysis: Narrative synthesis of existing literature and expert consensus; no primary data collection, systematic search strategy, or formal meta-analysis is reported. The report assesses diagnostic tests and highlights knowledge gaps and research opportunities.
Limitations
- Stated: the definition of chronic diarrhea remains debated, with loose stool form, increased frequency, stool weight, and duration criteria all at best arbitrary; most studies used to define the 4-week cutoff were done in industrialized countries, and information from less developed regions is needed.
- Stated: classification schemes need to be judged by their utility in individual patients who may not fit distinct categories; no simple diagnostic algorithm is currently possible because of the number of possible diagnoses, limited appreciation of pretest probabilities that depend on geography and patient specifics, variable test availability and performance, and costs.
- Evident from the text: as a narrative working party report, it does not provide a systematic review, formal evidence grading, or prospective validation of the proposed definitions and diagnostic approaches.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
0 Valid · 5 Not valid · 133 Not checked · 55 Own results and interpretations
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Measurement of peptide hormones is of value in the diagnosis and management of endocrine tumors causing diarrhea, but these are so rare that these tests are of little value in screening because there will be many more false-positives than true-positive results.”
§ Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosis > Abstract
plainstates a cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Patients with higher stool weights tended to have both loose stools and increased frequency.”
§ Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosis > Definition of chronic diarrhea
What the sources say
- Not matchedcites [8]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedgedstates an association- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Imaging the intestine with endoscopy and radiographic techniques is useful, and biopsy of the small intestine and colon for histological assessment provides key diagnostic information.”
§ Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosis > Abstract
plainstates a cause- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Most patients consider loose stools-more than frequency-as the key characteristic of diarrhea.4”
§ Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosis > Definition of chronic diarrhea
What the sources say
- Not matchedcites [4]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Not matched
In the paper
“Patients may report diarrhea as being present when stools are looser than normal (i.e.liquid or unformed), even when stool frequency is not increased.”
§ Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosis > Definition of chronic diarrhea
What the sources say
- Not matchedcites [4]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Not matched
79 more claims
Create a free account to see all 193 claims and every source verdict.
- Probably not a substantial claim. 47
- It may state two separate claims as one. 78
- The quote only partly states this claim. 7
Citations
Cites
Longstreth, G. F., Thompson, W. G., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.061 · Cited by 4,856
Self-citationA 5‐decade analysis of 13,715 carcinoid tumors
Modlin, I. M., Lye, K. D., & Kidd, M. (2003) · Cancer · doi:10.1002/cncr.11105 · Cited by 2,734
The Oslo definitions for coeliac disease and related terms
Ludvigsson, J. F., Leffler, D. A., Bai, J. C., Biagi, F., Fasano, A., Green, P. H. R., Hadjivassiliou, M., Kaukinen, K., Kelly, C. P., Leonard, J. N., et al. (2013) · Gut · doi:10.1136/gutjnl-2011-301346 · Cited by 1,721
ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease
Rubio‐Tapia, A., Hill, I. D., Kelly, C. P., Calderwood, A. H., & Murray, J. A. (2013) · The American Journal of Gastroenterology · doi:10.1038/ajg.2013.79 · Cited by 1,709
Whitehead, W. E., Palsson, O., & Jones, K. R. (2002) · Gastroenterology · doi:10.1053/gast.2002.32392 · Cited by 1,116
Postinfectious Irritable Bowel Syndrome
Spiller, R., & Garsed, K. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.074 · Cited by 1,024
Self-citationThe Random House dictionary of the English language
Urdang, L., & Stein, J. M. (1967) · Random House eBooks · Cited by 857
Celiac disease: Prevalence, diagnosis, pathogenesis and treatment
Gujral, N., Freeman, H. J., & Thomson, A. B. R. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i42.6036 · Cited by 737
Defecation frequency and timing, and stool form in the general population: a prospective study.
Heaton, K. W., Radvan, J., Cripps, H., Mountford, R. A., Braddon, F. E., & Hughes, A. O. (1992) · Gut · doi:10.1136/gut.33.6.818 · Cited by 733
Letter: Immunotherapy for colorectal cancer.
Hsu, L. Y., David, K., Serotkin, A. V., Godmilov, L., & Hirschhorn, K. (1976) · PubMed · Cited by 652
Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia
Verner, J. V., & Morrison, A. B. (1958) · The American Journal of Medicine · doi:10.1016/0002-9343(58)90075-5 · Cited by 630
Colonic Secretion of Water and Electrolytes Induced by Bile Acids: Perfusion Studies in Man
Mekhjian, H. S., Phillips, S. F., & Hofmann, A. F. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106644 · Cited by 584
Ong, D. K., Mitchell, S. B., Barrett, J. S., Shepherd, S. J., Irving, P. M., Biesiekierski, J. R., Smith, S., Gibson, P. R., & Muir, J. G. (2010) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2010.06370.x · Cited by 583
Review article: lactose intolerance in clinical practice – myths and realities
LOMER, M. C. E., PARKES, G. C., & SANDERSON, J. D. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03557.x · Cited by 566
Gradel, K. O., Nielsen, H. L., Schønheyder, H. C., Ejlertsen, T., Kristensen, B., & Nielsen, H. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.04.001 · Cited by 450
Niederle, M. B., Hackl, M., Kaserer, K., & Niederle, B. (2010) · Endocrine-Related Cancer · doi:10.1677/erc-10-0152 · Cited by 444
Orlistat-Associated Adverse Effects and Drug Interactions: A Critical Review
Filippatos, T. D., Derdemezis, C. S., Gazi, I. F., Nakou, E. S., Mikhailidis, D. P., & Elisaf, M. S. (2008) · Drug Safety · doi:10.2165/00002018-200831010-00005 · Cited by 434
Clinical features and natural history of Crohn's disease
Mekhjian, H. S., Switz, D. M., Melnyk, C. S., Rankin, G. B., & Brooks, R. K. (1979) · Gastroenterology · doi:10.1016/0016-5085(79)90389-5 · Cited by 406
BARRETT, J. S., GEARRY, R. B., MUIR, J. G., IRVING, P. M., ROSE, R., ROSELLA, O., HAINES, M. L., SHEPHERD, S. J., & GIBSON, P. R. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04237.x · Cited by 403
Siddiki, H. A., Fidler, J. L., Fletcher, J. G., Burton, S. S., Huprich, J. E., Hough, D. M., Johnson, C. D., Bruining, D. H., Loftus, E. V., Sandborn, W. J., et al. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.08.2027 · Cited by 389
Self-citationEffect of alcohol consumption on the gut.
Bode, C., & Christian Bode, J. (2003) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/s1521-6918(03)00034-9 · Cited by 379
AGA Technical Review on the Evaluation and Management of Chronic Diarrhea☆
Fine, K. D., & Schiller, L. R. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70513-5 · Cited by 376
Self-citationSmall-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial
Solem, C. A., Loftus, E. V., Fletcher, J. G., Baron, T. H., Gostout, C. J., Petersen, B. T., Tremaine, W. J., Egan, L. J., Faubion, W. A., Schroeder, K. W., et al. (2008) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2008.02.017 · Cited by 367
Self-citationThe Risk of Retention of the Capsule Endoscope in Patients with Known or Suspected Crohn's Disease
Cheifetz, A. S., Kornbluth, A. A., Legnani, P., Schmelkin, I., Brown, A., Lichtiger, S., & Lewis, B. S. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00761.x · Cited by 364
The diagnosis of small bowel bacterial overgrowth
Corazza, G. R., Menozzi, M. G., Strocchi, A., Rasciti, L., Vaira, D., Lecchini, R., Avanzini, P., Chezzi, C., & Gasbarrini, A. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90818-l · Cited by 351
Dumonceau, J., Delhaye, M., Tringali, A., Domínguez‐Muñoz, J. E., Poley, J., Arvanitaki, M., Costamagna, G., Costea, F., Deviere, J. M. E., Eisendrath, P., et al. (2012) · Endoscopy · doi:10.1055/s-0032-1309840 · Cited by 320
Picco, M. F. (2010) · Yearbook of Gastroenterology · doi:10.1016/s0739-5930(09)79399-7 · Cited by 314
Olesen, M., Eriksson, S., Bohr, J., Järnerot, G., & Tysk, C. (2004) · Gut · doi:10.1136/gut.2003.014431 · Cited by 311
Bessissow, T., Lemmens, B., Ferrante, M., Bisschops, R., Steen, K. V., Geboes, K. J., Assche, G. V., Vermeire, S., Rutgeerts, P. J., & Hertogh, G. D. (2012) · The American Journal of Gastroenterology · doi:10.1038/ajg.2012.301 · Cited by 293
Yu, D., Cheeseman, F., & Vanner, S. (2011) · Gut · doi:10.1136/gut.2009.205476 · Cited by 284
FAECAL INCONTINENCE: THE UNVOICED SYMPTOM
Leigh, R. J., & Turnberg, L. A. (1982) · The Lancet · doi:10.1016/s0140-6736(82)92413-8 · Cited by 279
Breath hydrogen testing in bacterial overgrowth of the small intestine
Kerlin, P., & Wong, L. (1988) · Gastroenterology · doi:10.1016/0016-5085(88)90173-4 · Cited by 274
The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota
Pardi, D. S., Loftus, E. V., Smyrk, T. C., Kammer, P. P., Tremaine, W. J., Schleck, C. D., Harmsen, W. S., Zinsmeister, A. R., Melton, L. J., & Sandborn, W. J. (2006) · Gut · doi:10.1136/gut.2006.105890 · Cited by 264
Self-citationGuidelines for the investigation of chronic diarrhoea, 2nd edition
Thomas, P. D., Forbes, A., Green, J., Howdle, P., Long, R., Playford, R. J., Sheridan, M., Stevens, R., Valori, R., Walters, J., et al. (2003) · Gut · doi:10.1136/gut.52.suppl_5.v1 · Cited by 262
Spiller, R. E., Humes, D. J., Campbell, E., Hastings, M. C., Neal, K. R., Dukes, G. E., & Whorwell, P. J. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04402.x · Cited by 246
Self-citationFord, A. C., Chey, W. D., Talley, N. J., Malhotra, A., Spiegel, B. M. R., & Moayyedi, P. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.22 · Cited by 243
How to Interpret Hydrogen Breath Tests
Ghoshal, U. C. (2011) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2011.17.3.312 · Cited by 233
Diagnosis and Treatment of Acute or Persistent Diarrhea
Pawlowski, S. W., Warren, C. A., & Guerrant, R. L. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.072 · Cited by 232
Surawicz, C. M., Haggitt, R. C., Husseman, M., & McFarland, L. V. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90124-4 · Cited by 225
Self-citationLithium: Updated Human Knowledge Using an Evidence-Based Approach
Grandjean, E. M., & Aubry, J. (2009) · CNS Drugs · doi:10.2165/00023210-200923050-00004 · Cited by 218
Accuracy of Serologic Tests and HLA-DQ Typing for Diagnosing Celiac Disease
Hadithi, M., Blomberg, B. M. E. V., Crusius, J. B. A., Bloemena, E., Kostense, P. J., Meijer, J. W. R., Mulder, C. J. J., Stehouwer, C. D. A., & Peña, A. S. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-5-200709040-00003 · Cited by 216
A genetic test which can be used to diagnose adult-type hypolactasia in children
Rasinperä, H., Savilahti, E., Enattah, N. S., Kuokkanen, M., Tötterman, N., Lindahl, H., Järvelä, I. E., & Kolho, K.-L. (2004) · Gut · doi:10.1136/gut.2004.040048 · Cited by 214
Hammer, H. F., Ana, C. A. S., Schiller, L. R., & Fordtran, J. S. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114267 · Cited by 211
Self-citationIntestinal fructose transport and malabsorption in humans
Jones, H. F., Butler, R. N., & Brooks, D. A. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00457.2010 · Cited by 210
The Lactulose Hydrogen Breath Test as a Diagnostic Test for Small-Bowel Bacterial Overgrowth
Rhodes, J. M., Middleton, P., & Jewell, D. P. (1979) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365527909179892 · Cited by 206
Chowdhury, R., & Forsmark, C. E. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01495.x · Cited by 204
Pardi, D. S., & Kelly, C. P. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.02.003 · Cited by 200
Self-citationAdherence to biopsy guidelines increases celiac disease diagnosis
Lebwohl, B., Kapel, R. C., Neugut, A. I., Green, P. H. R., & Genta, R. M. (2011) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2011.03.1236 · Cited by 199
Walker, E. A., Katon, W. J., Jemelka, R. P., & Roy-Byrne, P. P. (1992) · The American Journal of Medicine · doi:10.1016/0002-9343(92)90133-v · Cited by 195
Ravelli, A. M., Villanacci, V., Monfredini, C., Martinazzi, S., Grassi, V., & Manenti, S. (2010) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.153 · Cited by 194
Shin, A., Camilleri, M., Vijayvargiya, P., Busciglio, I., Burton, D., Ryks, M., Rhoten, D., Lueke, A., Saenger, A., Girtman, A., et al. (2013) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2013.04.020 · Cited by 192
The lactulose breath hydrogen test and small intestinal bacterial overgrowth.
Riordan, S. M., McIver, C. J., Bm, W., Duncombe, V. M., Bolin, T. D., & Thomas, M. C. (1996) · PubMed · Cited by 183
The prevalence, anatomic distribution, and diagnosis of colonic causes of chronic diarrhea
Fine, K. D., Seidel, R. H., & Do, K. (2000) · Gastrointestinal Endoscopy · doi:10.1016/s0016-5107(00)70362-2 · Cited by 177
Video Capsule Enteroscopy in the Diagnosis of Celiac Disease: A Multicenter Study
Rondonotti, E., Spada, C., Cave, D. R., Pennazio, M., Riccioni, M. E., Vitis, I. D., Schneider, D., Sprujevnik, T., Villa, F., Langelier, J., et al. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01238.x · Cited by 176
Petronienė, R., Dubcenco, E., Baker, J. P., Ottaway, C. A., Tang, S., Zanati, S. A., Streutker, C. J., Gardiner, G. W., Warren, R. E., & Jeejeebhoy, K. N. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.41069.x · Cited by 163
Capsule Retentions and Incomplete Capsule Endoscopy Examinations: An Analysis of 2300 Examinations
Höög, C., Bark, L.-Å., Arkani, J., Gorsetman, J., Broström, O., & Sjöqvist, U. (2011) · Gastroenterology Research and Practice · doi:10.1155/2012/518718 · Cited by 159
Bardhan, Bodemar, Geldof, Schütz, Heath, Mills, & Jacques (2000) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2000.00684.x · Cited by 158
CT Enterography: Principles, Trends, and Interpretation of Findings
Elsayes, K. M., Al-Hawary, M. M., Jagdish, J., Ganesh, H. S., & Platt, J. F. (2010) · Radiographics · doi:10.1148/rg.307105052 · Cited by 155
Usefulness of Colonoscopy With Biopsy in The Evaluation of Patients With Chronic Diarrhea
Shah, R. J., Fenoglio‐Preiser, C. M., Bleau, B. L., & Giannella, R. A. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03745.x · Cited by 150
Self-citationMerrick, M. V., Eastwood, M. A., & Ford, M. J. (1985) · BMJ · doi:10.1136/bmj.290.6469.665 · Cited by 150
Spiegel, B. M. R., DeRosa, V. P., Gralnek, I. M., Wang, V. C., & Dulai, G. S. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.03.012 · Cited by 146
Autoimmune Enteropathy: A Review and Update of Clinical Management
Gentile, N. M., Murray, J. A., & Pardi, D. S. (2012) · Current Gastroenterology Reports · doi:10.1007/s11894-012-0276-2 · Cited by 144
Self-citationFoley, S., Garsed, K. C., Singh, G., Duroudier, N. P., Swan, C., Hall, I. P., Zaitoun, A. M., Bennett, A. J., Marsden, C. A., Holmes, G. K. T., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.01.052 · Cited by 143
Self-citationKeszthelyi, D., Jansen, S. V., Schouten, G. A., de Kort, S., Scholtes, B., Engels, L. G. J. B., & Masclee, A. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04453.x · Cited by 142
Williams, A. J., Merrick, M. V., & Eastwood, M. A. (1991) · Gut · doi:10.1136/gut.32.9.1004 · Cited by 141
An Outbreak of a Newly Recognized Chronic Diarrhea Syndrome Associated With Raw Milk Consumption
Osterholm, M. T., MacDonald, K. L., White, K. E., Wells, J. G., Spika, J. S., Potter, M. E., Forfang, J. C., Sorenson, R. M., Milloy, P. T., & Blake, P. A. (1986) · JAMA · doi:10.1001/jama.1986.03380040058029 · Cited by 139
Dietary Fiber and Personality Factors as Determinants of Stool Output
Tucker, D. M., Sandstead, H. H., Logan, G. M., Klevay, L. M., Mahalko, J. R., Johnson, L. K., Inman, L., & Inglett, G. E. (1981) · Gastroenterology · doi:10.1016/s0016-5085(81)80112-6 · Cited by 138
Burgmann, T., Clara, I., Graff, L., Walker, J., Lix, L., Rawsthorne, P., McPhail, C., Rogala, L., Miller, N., & Bernstein, C. N. (2006) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.03.003 · Cited by 135
Cash, B. D., Rubenstein, J. H., Young, P. E., Gentry, A., Nojkov, B., Lee, D. K., Andrews, A. H., Dobhan, R. R., & Chey, W. D. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.06.084 · Cited by 134
Systematic Evaluation of the Causes of Chronic Watery Diarrhea With Functional Characteristics
Fernández‐Bañares, F., Esteve, M., Salas, A., Alsina, M., Farré, C., González, C., Buxeda, M., Forné, M., Rosinach, M., Espinós, J. C., et al. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01438.x · Cited by 134
Determinants of decreased fecal consistency in patients with diarrhea
Wenzl, H., Fine, K. D., Schiller, L. R., & Fordtran, J. S. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90134-5 · Cited by 133
Self-citationPlevy, S. E., Silverberg, M. S., Lockton, S., Stockfisch, T., Croner, L. J., Stachelski, J., Brown, M., Triggs, C., Chuang, E., Princen, F., et al. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e318280b19e · Cited by 130
Characterization of the Alternating Bowel Habit Subtype in Patients with Irritable Bowel Syndrome
Tillisch, K., Labus, J. S., Naliboff, B. D., Bolus, R. R., Shetzline, M. A., Mayer, E. A., & Chang, L. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.41211.x · Cited by 130
Taura, N., Ichikawa, T., Miyaaki, H., Kadokawa, Y., Tsutsumi, T., Tsuruta, S., Kato, Y., INOUE, O., Kinoshita, N., Ohba, K., et al. (2012) · Gastroenterology Research and Practice · doi:10.1155/2012/317580 · Cited by 129
Methods for Diagnosis of Bile Acid Malabsorption in Clinical Practice
Vijayvargiya, P., Camilleri, M., Shin, A., & Saenger, A. K. (2013) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2013.04.029 · Cited by 127
Celiac Disease and Autoimmunity: Review and Controversies
Denham, J. M., & Hill, I. D. (2013) · Current Allergy and Asthma Reports · doi:10.1007/s11882-013-0352-1 · Cited by 126
CT enterography: review of technique and practical tips
Ilangovan, R., Burling, D. N., George, A., Gupta, A. K., Marshall, M. B., & Taylor, S. A. (2012) · British Journal of Radiology · doi:10.1259/bjr/27973476 · Cited by 126
The Value of Double-Balloon Enteroscopy in Patients With Refractory Celiac Disease
Hadithi, M., Al-Toma, A. A., Oudejans, J. J., Bodegraven, A. A. V., Mulder, C. J. J., & Jacobs, M. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01122.x · Cited by 125
Symptoms and Haematologic Features in Consecutive Adult Coeliac Patients
Bodé, S., & Gudmand-Höyer, E. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609031627 · Cited by 119
Utility of red flag symptom exclusions in the diagnosis of irritable bowel syndrome
WHITEHEAD, W. E., PALSSON, O. S., FELD, A. D., LEVY, R. L., VON KORFF, M., TURNER, M. J., & DROSSMAN, D. A. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02956.x · Cited by 118
Radiological and nuclear medicine imaging of gastroenteropancreatic neuroendocrine tumours
Sundin, A. (2012) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2012.12.004 · Cited by 116
Fecal Markers: Calprotectin and Lactoferrin
Abraham, B. P., & Kane, S. V. (2012) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2012.01.007 · Cited by 115
Fecal osmotic gap and pH in experimental diarrhea of various causes
Eherer, A. J., & Fordtran, J. S. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)90845-p · Cited by 113
An update in the diagnosis of coeliac disease
Walker, M. M., & Murray, J. A. (2010) · Histopathology · doi:10.1111/j.1365-2559.2010.03680.x · Cited by 113
Pancreatic function testing: Here to stay for the 21st century
Lieb, J. G., II, & Draganov, P. V. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.3149 · Cited by 112
Carbohydrate malabsorption. Its measurement and its contribution to diarrhea.
Hammer, H. F., Fine, K. D., Ana, C. A. S., Porter, J. L., Schiller, L. R., & Fordtran, J. S. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114927 · Cited by 109
Self-citationCoste, J.-F., Vuiblet, V., Moustapha, B., Bouin, A., Lavaud, S., Toupance, O., de Rougemont, A., Bénéjat, L., Mégraud, F., Wolak‐Thierry, A., et al. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.03366-12 · Cited by 104
Krejs, G. J. (1987) · The American Journal of Medicine · doi:10.1016/0002-9343(87)90425-6 · Cited by 103
Self-citationEvaluation of Ileal Function Using 23-Selena-25-Homotaurocholate, a γ-Labeled Conjugated Bile Acid
Nyhlin, H., Merrick, M. V., Eastwood, M. A., & Brydon, W. G. (1983) · Gastroenterology · doi:10.1016/s0016-5085(83)80167-x · Cited by 100
Symptoms and signs in individuals with serology positive for celiac disease but normal mucosa
Ludvigsson, J. F., Brandt, L., & Montgomery, S. (2009) · BMC Gastroenterology · doi:10.1186/1471-230x-9-57 · Cited by 100
Diagnostic Yield of Capsule Endoscopy in Refractory Celiac Disease
Barret, M., Malamut, G., Rahmi, G., Samaha, E., Edery, J., Verkarre, V., Macintyre, E. A., Lenain, É., Châtellier, G., Cerf–Bensussan, N., et al. (2012) · The American Journal of Gastroenterology · doi:10.1038/ajg.2012.199 · Cited by 99
Bowel habit after cholecystectomy: Physiological changes and clinical implications
Fort, J. M., Azpiroz, F., Casellas, F., Andreu, J., & Malagelada, J. (1996) · Gastroenterology · doi:10.1053/gast.1996.v111.pm8780565 · Cited by 99
Palsson, O. S., Baggish, J. S., Turner, M. J., & Whitehead, W. E. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2011.358 · Cited by 99
Persistent Diarrhea in Travelers
DuPont, H. L., & Capsuto, E. G. (1996) · Clinical Infectious Diseases · doi:10.1093/clinids/22.1.124 · Cited by 98
Fat Malabsorption Screening in Chronic Pancreatitis
Vincent, D., Delhaye, M., Frederic, C., & Jacques, D. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.30661.x · Cited by 96
Diagnosis of chronic pancreatitis: Functional testing
Domínguez‐Muñoz, J. E. (2010) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2010.03.008 · Cited by 96
Tursi, A. (2010) · Digestive Diseases and Sciences · doi:10.1007/s10620-010-1230-5 · Cited by 95
Savas, L. S., White, D. L., Wieman, M. S., Daci, K., Fitzgerald, S. J., SMITH, S. L., Tan, G., Graham, D. P., Cully, J. A., & EL‐SERAG, H. B. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03847.x · Cited by 95
Zusman, R. M., Christensen, D. M., Federman, E. B., Kochar, M. S., McCarron, D. A., Porush, J. G., & Spitalewitz, S. (1987) · The American Journal of Medicine · doi:10.1016/0002-9343(87)90209-9 · Cited by 95
Martín-Iguacel, R., Llibre, J. M., Nielsen, H. I., Heras, E., Matas, L., Lugo, R., Clotet, B., & Sirera, G. (2010) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-010-0959-2 · Cited by 95
Microscopic colitis associated with lansoprazole: Report of two cases and a review of the literature
Chande, N., & Driman, D. K. (2006) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520600997296 · Cited by 93
Review article: the aetiology, investigation and management of diarrhoea in the HIV-positive patient
Feasey, N., Healey, P. R., & Gordon, M. A. (2011) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2011.04781.x · Cited by 89
da Silva, J. G. N., de Brito, T., Damião, A. O. M. C., Laudanna, A. A., & Sipahi, A. M. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000190760.72992.ed · Cited by 89
Effect of Caffeine on the Human Small Intestine
Wald, A., Back, C., & Bayless, T. M. (1976) · Gastroenterology · doi:10.1016/s0016-5085(76)80353-8 · Cited by 86
Glucose malabsorption associated with rapid intestinal transit.
Sellin, J. H., & Hart, R. (1992) · PubMed · Cited by 85
Self-citationJones, R. H., Latinovic, R., Charlton, J., & Gulliford, M. C. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.03044.x · Cited by 80
Bauer, T., Schwacha, H., Steinbrückner, B., Brinkmann, F., Ditzen, A. K., Kist, M., & Blum, H. E. (2000) · Journal of Hepatology · doi:10.1016/s0168-8278(00)80273-1 · Cited by 80
Diarrhea Caused By Carbohydrate Malabsorption
Hammer, H. F., & Hammer, J. (2012) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2012.06.003 · Cited by 78
Prevalence and natural history of potential celiac disease in adult patients
Biagi, F., Trotta, L., Alfano, C., Balduzzi, D., Staffieri, V., Bianchi, P. I., Marchese, A., Vattiato, C., Zilli, A., Luinetti, O., et al. (2013) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2013.777470 · Cited by 78
Utility of positron emission tomography/CT in the evaluation of small bowel pathology
Cronin, C. G., Scott, J. A., Kambadakone, A. R., Catalano, O. A., Sahani, D. V., Blake, M. A., & McDermott, S. (2012) · British Journal of Radiology · doi:10.1259/bjr/64534573 · Cited by 74
Thaysen, E. H., Orholm, M. K., Arnfred, T., Carl, J., & Rødbro, P. (1982) · Gut · doi:10.1136/gut.23.10.862 · Cited by 74
Abraham, B. P., & Sellin, J. H. (2007) · Current Gastroenterology Reports · doi:10.1007/s11894-007-0044-x · Cited by 74
Self-citationClinical characteristics of collagenous and lymphocytic colitis
Koskela, R., Niemelä, S., Karttunen, T. J., & Lehtola, J. (2004) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520410006468 · Cited by 74
Chronic, unexplained diarrhea: are biopsies necessary if colonoscopy is normal?
Marshall, J. B., Singh, R., & Diaz‐Arias, A. A. (1995) · PubMed · Cited by 73
Stotzer, P., & Kilander, A. F. (2000) · Digestion · doi:10.1159/000007753 · Cited by 72
The Self-Limited Nature of Chronic Idiopathic Diarrhea
Afzalpurkar, R. G., Schiller, L. R., Little, K. H., Santangelo, W. C., & Fordtran, J. S. (1992) · New England Journal of Medicine · doi:10.1056/nejm199212243272605 · Cited by 71
Self-citationFosnes, G. S., Lydersen, S., & Farup, P. G. (2011) · BMC Clinical Pharmacology · doi:10.1186/1472-6904-11-2 · Cited by 70
Hahn, J.-U., Kerner, W., Maisonneuve, P., Lowenfels, A. B., & Lankisch, P. G. (2008) · Pancreas · doi:10.1097/mpa.0b013e3181656f8 · Cited by 70
Sinha, L., Liston, R., Testa, H. J., & Moriarty, K. J. (1998) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1998.00388.x · Cited by 69
MR Imaging Techniques for Pancreas
Tirkes, T., Menias, C. O., & Sandrasegaran, K. (2012) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2012.03.003 · Cited by 64
The Strategy for Biopsies of the Terminal Ileum Should Be Evidence Based
Geboes, K. J. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01190.x · Cited by 62
Diarrhoea due to small bowel diseases
Murray, J. A., & Rubio‐Tapia, A. (2012) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2012.11.013 · Cited by 60
Postinfective Diarrhoea and Bile Acid Malabsorption
Niaz, S. K., Sandrasegaran, K., Renny, F. H., & Jones, B. J. M. (1997) · Journal of the Royal College of Physicians of London · doi:10.1016/s0035-8819(25)00270-3 · Cited by 59
Schiller, L. R., Hogan, R. B., Morawski, S. G., Ana, C. A. S., Bern, M. J., Norgaard, R. P., Bo‐Linn, G. W., & Fordtran, J. S. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)90852-3 · Cited by 59
Self-citationEpidemiology of slow and fast colonic transit using a scale of stool form in a community
Choung, R. S., Locke, G. R., ZINSMEISTER, A. R., Schleck, C. D., & Talley, N. J. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03456.x · Cited by 58
Lembcke, B., Braden, B., & Caspary, W. F. (1996) · Gut · doi:10.1136/gut.39.5.668 · Cited by 58
Schiller, L. R. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.05.028 · Cited by 58
Self-citationA Neuroendocrine Tumor Syndrome from Cholecystokinin Secretion
Rehfeld, J. F., Federspiel, B., & Bardram, L. (2013) · New England Journal of Medicine · doi:10.1056/nejmc1215137 · Cited by 57
CT Findings in Adult Celiac Disease
Scholz, F. J., Afnan, J., & Behr, S. C. (2011) · Radiographics · doi:10.1148/rg.314105215 · Cited by 55
Effect of cholecystectomy on bowel function: a prospective, controlled study
Hearing, S. D., Thomas, L. A., Heaton, K. W., & Hunt, L. P. (1999) · Gut · doi:10.1136/gut.45.6.889 · Cited by 53
Stevens, T., Dumot, J. A., Parsi, M. A., Zuccaro, G., & Vargo, J. J. (2010) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-1084-x · Cited by 52
Prognosis of Adult-Onset Idiopathic Bile Acid Malabsorption
Rössel, P. (1999) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655299750026047 · Cited by 51
Emerging technologies in upper gastrointestinal endoscopy and celiac disease
Cammarota, G., Fedeli, P., & Gasbarrini, A. (2008) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep1298 · Cited by 46
Diagnostic value of confocal endomicroscopy in celiac disease
Günther, U., Daum, S., Heller, F., Schümann, M., Loddenkemper, C., Grünbaum, M., Zeitz, M., & Bojarski, C. (2010) · Endoscopy · doi:10.1055/s-0029-1243937 · Cited by 46
Characterization of Episodes of Irritable Bowel Syndrome Using Ecological Momentary Assessment
Weinland, S. R., Morris, C. B., Hu, Y., Leserman, J., Bangdiwala, S. I., & Drossman, D. A. (2011) · The American Journal of Gastroenterology · doi:10.1038/ajg.2011.170 · Cited by 44
Gillams, A. R., & Lees, W. R. (2007) · European Radiology · doi:10.1007/s00330-007-0708-9 · Cited by 43
Definitions, pathophysiology, and evaluation of chronic diarrhoea
Schiller, L. R. (2012) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2012.11.011 · Cited by 42
Self-citationGastrointestinal symptoms in diabetes mellitus, and their relation to anxiety and depression
de Kort, S., Kruimel, J. W., Sels, J. P. J. E., Arts, I. C. W., Schaper, N. C., & Masclee, A. (2012) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2012.01.021 · Cited by 42
Diagnostic value of fasting plasma peptide concentrations in patients with chronic diarrhea
Schiller, L. R., Rivera, L. M., Santangelo, W. C., Little, K. H., & Fordtran, J. S. (1994) · Digestive Diseases and Sciences · doi:10.1007/bf02090374 · Cited by 39
Self-citationSimpson, K. L., & Jarvis, B. (2000) · Drugs · doi:10.2165/00003495-200059050-00012 · Cited by 38
Infectious causes of chronic diarrhoea
Kaiser, L., & Surawicz, C. M. (2012) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2012.11.001 · Cited by 38
Self-citationKhanna, S., Pardi, D. S., Rosenblatt, J. E., Patel, R., Kammer, P. P., & Baddour, L. M. (2012) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e3182432273 · Cited by 36
Self-citationIdiopathic bile acid malabsorption: long-term outcome.
Luman, W., Williams, A. J., Merrick, M. V., & Eastwood, M. A. (1995) · PubMed · Cited by 35
Drug-induced, factitious, & idiopathic diarrhoea
Abraham, B. P., & Sellin, J. H. (2012) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2012.11.007 · Cited by 35
Self-citationPimentel, M., Hwang, L. J., Melmed, G., Low, K., Vasiliauskas, E., Ippoliti, A., Yang, J. M., Lezcano, S., Conklin, J. L., & Sahakian, A. B. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0694-z · Cited by 33
Burri, E., Manz, M., Rothen, C., Rossi, L., Beglinger, C., & Lehmann, F. S. (2012) · Clinica Chimica Acta · doi:10.1016/j.cca.2012.11.008 · Cited by 32
Fromm, H., Tunuguntla, A. K., Malavolti, M., Sherman, C. A., & Ceryak, S. M. (1987) · Digestive Diseases and Sciences · doi:10.1007/bf01296685 · Cited by 31
Steffer, K. J., Ana, C. A. S., Cole, J. A., & Fordtran, J. S. (2012) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2012.06.001 · Cited by 30
Shelton, J. H., Ana, C. A. S., Thompson, D. R., Emmett, M., & Fordtran, J. S. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2006.077883 · Cited by 30
Adult eosinophilic gastroenteritis and hypereosinophilic syndromes
Freeman, H. J. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.6771 · Cited by 29
... (2012) · Molecular Imaging and Radionuclide Therapy · doi:10.4274/mirt.80299 · Cited by 28
Fecal bile acid excretion pattern in cholecystectomized patients
Breuer, N. F., Jaekel, S., Dommes, P., & Goebell, H. (1986) · Digestive Diseases and Sciences · doi:10.1007/bf01303216 · Cited by 28
Sciarretta, G., Furno, A., Morrone, B., & Malaguti, P. (1994) · PubMed · Cited by 27
13C Breath Tests for the Assessment of Exocrine Pancreatic Function
Braden, B. (2010) · Pancreas · doi:10.1097/mpa.0b013e3181dbf330 · Cited by 27
High Somatic Symptom Burdens and Functional Gastrointestinal Disorders
Sayuk, G. S., Elwing, J. E., Lustman, P. J., & Clouse, R. E. (2007) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.11.024 · Cited by 26
Fellous, K., Jian, R., Haniche, M., Marteau, P. R., Messing, B., Rain, J., & Modigliani, R. (1994) · PubMed · Cited by 26
Safety profile of orlistat: results of a prescription-event monitoring study
Acharya, N. V., Wilton, L., & Shakir, S. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803323 · Cited by 25
Diarrhea Caused By Circulating Agents
Fabian, E., Kump, P. K., & Krejs, G. J. (2012) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2012.06.008 · Cited by 25
Self-citationAre Hydrogen Breath Tests Valid in the Elderly?
Mahon, M. M., Gibbons, N., Mullins, E., O’Moore, R. R., Keane, C. T., Walsh, J. B., & Coakley, D. (2009) · Gerontology · doi:10.1159/000213769 · Cited by 23
Fecal elastase1 and acid steatocrit estimation in chronic pancreatitis
Girish, B. N., Rajesh, G., Vaidyanathan, K., & Balakrishnan, V. (2009) · Indian Journal of Gastroenterology · doi:10.1007/s12664-009-0079-z · Cited by 23
A Large Outbreak of Brainerd Diarrhea Associated with a Restaurant in the Red River Valley, Texas
Kimura, A. C., Mead, P. S., Walsh, B., Alfano, E., Gray, S. K., Durso, L. M., Humphrey, C. D., Monroe, S. S., Visvesvera, G. S., Puhr, N. D., et al. (2006) · Clinical Infectious Diseases · doi:10.1086/504805 · Cited by 23
The Promise and Pitfalls of Serologic Testing in Inflammatory Bowel Disease
Sellin, J. H., & Shah, R. (2012) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2012.01.001 · Cited by 22
Self-citationEvaluation of the Applicability of the SeHCAT Test in the Investigation of Patients with Diarrhoea
Orholm, M. K., Pedersen, J. O., Arnfred, T., Rødbro, P., & Thaysen, E. H. (1988) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365528809093859 · Cited by 20
Carbohydrate Challenge Tests: Do You Need to Measure Methane?
Knudsen, C., & Palma, J. A. D. (2012) · Southern Medical Journal · doi:10.1097/smj.0b013e318252d428 · Cited by 18
van Tilburg, A. J., de Rooij, F. W., van den Berg, J. W. O., Kooij, P. P. M., & BLANKENSTEIN, M. V. (1991) · PubMed · Cited by 17
Risk of diarrhoea, Clostridium difficile and cefotaxime in the elderly
Starr, J. M., & Impallomeni, M. (1997) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(97)87728-1 · Cited by 17
Colorectal Normal Histology and Histopathologic Findings in Patients with Chronic Diarrhea
Langner, C. (2012) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2012.06.005 · Cited by 15
Lee, L., & Conwell, D. L. (2012) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2012.03.002 · Cited by 15
Gupta, A., Derbes, C. J., & Sellin, J. H. (2005) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000182866.89895.3f · Cited by 13
Self-citationEndoscopic ultrasonography to evaluate pancreatitis
Albashir, S. M., & Stevens, T. (2012) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.79a.11092 · Cited by 11
Schiller, L. R., & Sellin, J. H. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6189-2.00015-9 · Cited by 7
Self-citationGastrointestinal Endocrine Tumors
Krejs, G. J. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609094762 · Cited by 4
Self-citationMinutoli, F., Herberg, A., Sindoni, A., Cardile, D., Cucinotta, M., & Baldari, S. (2013) · Annals of Nuclear Medicine · doi:10.1007/s12149-013-0732-6 · Cited by 4
CT enteroclysis in the developing world: How we do it, and the pathology we see
van der Merwe, B. S., Ackermann, C., & Els, H. (2013) · European Journal of Radiology · doi:10.1016/j.ejrad.2013.03.018 · Cited by 3
Research works printed but not linked: 1
- Schiller LR, 2011, Conn's Current Therapy 2011, 553
Cited by
Arasaradnam, R. P., Brown, S., Forbes, A., Fox, M. R., Hungin, P., Kelman, L., Major, G., O’Connor, M., Sanders, D. S., Sinha, R., et al. (2018) · Gut · doi:10.1136/gutjnl-2017-315909 · Cited by 332
Chronic Diarrhea: Diagnosis and Management
Schiller, L. R., Pardi, D. S., & Sellin, J. H. (2016) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2016.07.028 · Cited by 270
Self-citationPathophysiology, Evaluation, and Management of Chronic Watery Diarrhea
Camilleri, M., Sellin, J. H., & Barrett, K. E. (2016) · Gastroenterology · doi:10.1053/j.gastro.2016.10.014 · Cited by 171
Self-citationSingh, P., Mitsuhashi, S., Ballou, S., Rangan, V., Sommers, T. F., Cheng, V., Iturrino-Moreda, J., Friedlander, D., Nee, J. W., & Lembo, A. J. (2018) · The American Journal of Gastroenterology · doi:10.1038/ajg.2018.24 · Cited by 103
Diarrhoea in the critically ill
Blaser, A. R., Deane, A. M., & Fruhwald, S. M. (2015) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000188 · Cited by 87
Metadata
- Authors
- Schiller, L. R., Pardi, D. S., Spiller, R., Semrad, C. E., Surawicz, C. M., Giannella, R. A., Krejs, G. J., Farthing, M. J. G., & Sellin, J. H.
- Affiliations
- Baylor University Medical Center (US)
- Mayo Clinic (US)
- Nottingham Digestive Diseases Centre Queens Medical Centre Nottingham UK
- University of Chicago (US)
- University of Washington (US)
- University of Cincinnati (US)
- Medical University of Graz (AT)
- University of Sussex (GB)
- Baylor College of Medicine (US)
- Corresponding author
- Schiller, Lawrence R
- Venue
- Journal of Gastroenterology and Hepatology
- Publisher
- Wiley
- Published
- 2013-12-19
- Volume
- 29
- Issue
- 1
- Pages
- 6-25
- ISSN
- 0815-9319 (ISSN-L)
- 1440-1746
- OpenAlex
- W1521766620
- Cited by
- 95
- References
- 175
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 6 · 2023: 11 · 2022: 5 · 2021: 11 · 2020: 10 · 2019: 12 · 2018: 7 · 2017: 7 · 2016: 11 · 2015: 4
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Gastroenterology and Hepatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Microscopic Colitis
- Health Sciences › Medicine › Gastroenterology › Digestive system and related health
- Keywords
- chronic diarrhea, differential diagnosis, Bristol Stool Form Scale, stool consistency, small bowel biopsy, endomicroscopy, gut microbiota, autoimmune enteropathy, inflammatory bowel disease, endocrine tumors, carbohydrate malabsorption, small intestinal bacterial overgrowth, intestinal transit, bile acid malabsorption, bile acid sequestrants, breath test
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Bile Acids and Salts, Breath Tests, China, Chronic Disease, Diarrhea, Feces, Female, Humans, Intestine, Small, Magnetic Resonance Imaging, Male, Middle Aged, Pancreatic Function Tests, Serologic Tests, Tomography, X-Ray Computed, Endoscopy, Gastrointestinal, Peptide Hormones, Steatorrhea, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
A language model drew the claims from the paper on 2026-11-14, under version 3 of the claim definition (model deepseek-v4.1-flash, prompt extract-v3).
A second model labelled each claim on 2026-11-14 (model jev-1.13-20260917, definition revision gold-guideline-v0.2).
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
