The DOI matches its Crossref record; 202 of the 202 references it cites were found in a registry or an index.
Neuroinflammation: the devil is in the details
Open accessAbstract
There is significant interest in understanding inflammatory responses within the brain and spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are generally referred to as ‘neuroinflammatory’. Aspects of neuroinflammation vary within the context of disease, injury, infection, or stress. The context, course, and duration of these inflammatory responses are all critical aspects in the understanding of these processes and their corresponding physiological, biochemical, and behavioral consequences. Microglia, innate immune cells of the CNS , play key roles in mediating these neuroinflammatory responses. Because the connotation of neuroinflammation is inherently negative and maladaptive, the majority of research focus is on the pathological aspects of neuroinflammation. There are, however, several degrees of neuroinflammatory responses, some of which are positive. In many circumstances including CNS injury, there is a balance of inflammatory and intrinsic repair processes that influences functional recovery. In addition, there are several other examples where communication between the brain and immune system involves neuroinflammatory processes that are beneficial and adaptive. The purpose of this review is to distinguish different variations of neuroinflammation in a context‐specific manner and detail both positive and negative aspects of neuroinflammatory processes. image In this review, we will use brain and spinal cord injury, stress, aging, and other inflammatory events to illustrate the potential harm and benefits inherent to neuroinflammation. Context, course, and duration of the inflammation are highly important to the interpretation of these events, and we aim to provide insight into this by detailing several commonly studied insults. This article is part of the 60th anniversary supplemental issue .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The “immune sentinel” of the retina, the resting microglia, determines the nature of the innate immune response in these spaces and is the key checkpoint between limiting or aggravating neuroinflammation [66].”
From Risk mitigation of immunogenicity: a key to personalized retinal gene therapy (2021) · cites this paper as [66]
In the citing paper
“Inflammatory immune responses for ocular gene therapies become harder to predict in the clinical setting, as both physiological and barrier functions of immune privilege may already be compromised by aging or the ocular disorder physiopathological conditions such as inflammation or oxidative stress induction [21,66,67].”
From Risk mitigation of immunogenicity: a key to personalized retinal gene therapy (2021) · cites this paper as [66]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
From inflammation to sickness and depression: when the immune system subjugates the brain
Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175
ATP mediates rapid microglial response to local brain injury in vivo
Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913
The blood-brain barrier/neurovascular unit in health and disease
Hawkins, B. T., & Davis, T. P. (2005) · Pharmacological Reviews · doi:10.1124/pr.57.2.4 · Cited by 2,661
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., & Stefani, M. (2002) · Nature · doi:10.1038/416507a · Cited by 2,434
Kigerl, K. A., Gensel, J. C., Ankeny, D. P., Alexander, J. K., Donnelly, D. J., & Popovich, P. G. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3257-09.2009 · Cited by 2,130
Moderate and severe traumatic brain injury in adults
Maas, A. I., Stocchetti, N., & Bullock, R. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70164-9 · Cited by 2,123
Elmore, M. R. P., Najafi, A. R., Koike, M. A., Dagher, N. N., Spangenberg, E. E., Rice, R. A., Kitazawa, M., Matusow, B., Nguyen, H., West, B. L., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.040 · Cited by 1,968
Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960
Flagged first, then by citations
Research works printed but not linked: 2
- 10.1016/S1071-5576(00)00038-1 · DOI
- 10.1016/j.bbi.2010.02.001 · DOI · Paper page
Cited by
Sorted by citations
Items 601–700 of 1,000
Broome, S. T., & Castorina, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031845 · Cited by 18
Edwards, K. A., Leete, J. J., Smith, E. G., Quick, A., Modica, C. M., Wassermann, E. M., Polejaeva, E., Dell, K. C., LoPresti, M. L., Walker, P., et al. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.723923 · Cited by 19
Nam, B., Lee, W. H., Sarkar, S., Kim, J., Bhise, A., Park, H., Kim, J. Y., Huynh, P. T., Rajkumar, S., Lee, K., et al. (2022) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-022-05854-1 · Cited by 19
Gao, X., Cao, Z., Tan, H., Li, P., Su, W., Wan, T., & Guo, W. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.903472 · Cited by 18
do Amaral, C. L., Martins, Í. D. C. A., Verás, A. C. C., Simabuco, F. M., Ross, M. G., Desai, M., Ignácio-Souza, L. M., Milanski, M., Torsoni, A. S., & Torsoni, M. A. (2022) · Cells · doi:10.3390/cells11142195 · Cited by 18
Reymond, S., Vujić, T., & Sanchez, J. (2022) · Biomedicines · doi:10.3390/biomedicines10092147 · Cited by 20
The P2X7 receptor in mood disorders: Emerging target in immunopsychiatry, from bench to bedside
von Mücke-Heim, I.-A., & Deussing, J. M. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109366 · Cited by 19
Transcriptional and epigenetic regulation of microglia in substance use disorders
Vilca, S. J., Margetts, A. V., Pollock, T. A., & Tuesta, L. M. (2023) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2023.103838 · Cited by 20
Ayilara, G. O., & Owoyele, B. V. (2023) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2023.05.010 · Cited by 18
Rueda-Gensini, L., Serna, J. A., Rubio, D., Orozco, J. C., Bolaños, N. I., Cruz, J. C., & Muñoz-Camargo, C. (2023) · Biofabrication · doi:10.1088/1758-5090/ace21b · Cited by 20
Inflammation in Posttraumatic Stress Disorder: Dysregulation or Recalibration?
Patas, K., Baker, D. G., Chrousos, G. P., & Agorastos, A. (2023) · Current Neuropharmacology · doi:10.2174/1570159x21666230807152051 · Cited by 21
Soni, S., Lukhey, M. S., Thawkar, B. S., Chintamaneni, M., Kaur, G., Joshi, H., Ramniwas, S., & Tuli, H. S. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-02994-z · Cited by 19
Ruan, Q., Geng, Y., Zhao, M., Zhang, H., Cheng, X., Zhao, T., Yue, X., Jiang, X., Jiang, X., Hou, X., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116342 · Cited by 20
A Scoping Review of the Mechanisms Underlying Developmental Anesthetic Neurotoxicity
Borzage, M., & Peterson, B. S. (2024) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000006897 · Cited by 18
Neuroimmunological effects of omega-3 fatty acids on migraine: a review
Chen, T., Yang, C., Tsai, I., Yang, H.-W., Hsu, Y., Chang, C., & Yang, C. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1366372 · Cited by 18
Amyloid‐β in Alzheimer's disease: Structure, toxicity, distribution, treatment, and prospects
Yu, Y., Yu, S., Battaglia, G., & Tian, X. (2024) · Ibrain · doi:10.1002/ibra.12155 · Cited by 19
Neuromodulatory effects of leukotriene receptor antagonists: A comprehensive review
Sood, R., Anoopkumar‐Dukie, S., Rudrawar, S., & Hall, S. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176755 · Cited by 20
Mechanism of effect and therapeutic potential of NLRP3 inflammasome in spinal cord injury
Gu, H.-Y., & Liu, N. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.115059 · Cited by 18
Guerreiro, D., Almeida, A., & Ramalho, R. (2024) · Nutrients · doi:10.3390/nu16233994 · Cited by 18
Bollaerts, I., houcke, J. V., Beckers, A., Lemmens, K., Vanhunsel, S., Groef, L. D., & Moons, L. (2019) · Mediators of Inflammation · doi:10.1155/2019/6135795 · Cited by 18
Isaiah, S., Loots, D. T., Solomons, R., van der Kuip, M., van Furth, A. M., & Mason, S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00296 · Cited by 20
Priya, R., & Brutkiewicz, R. R. (2020) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2020.577428 · Cited by 18
Why Do Levels Of Anti-inflammatory Cytokines Increase During Memory Acquisition?
Levin, S. G., Pershina, E. V., Bugaev-Makarovskiy, N. A., Chernomorets, I. Y., Konakov, M. V., & Arkhipov, V. I. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.08.007 · Cited by 21
Zhang, S., Liu, M., Liu, D.-N., Shang, Y.-F., Wang, Y., & Du, G. (2022) · Molecules · doi:10.3390/molecules27092990 · Cited by 18
Hashimoto, O., Kuniishi, H., Nakatake, Y., Yamada, M., Wada, K., & Sekiguchi, M. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.09.013 · Cited by 17
ApoE: The Non-Protagonist Actor in Neurological Diseases
Grimaldi, L., Bovi, E., Formisano, R., & Sancesario, G. M. (2024) · Genes · doi:10.3390/genes15111397 · Cited by 18
Melatonin and the nervous system: nanomedicine perspectives
Luo, F., Deng, Y., Angelov, B., & Angelova, A. (2025) · Biomaterials Science · doi:10.1039/d4bm01609b · Cited by 17
Hladkykh, F. V., Liadova, T., Matvieienko, M. S., Komorovsky, R., Smiyan, S., & Student, V. (2026) · Journal of Pain Research · doi:10.2147/jpr.s571311 · Cited by 22
Reyes-Mendoza, J., & Morales, T. (2020) · Brain Research · doi:10.1016/j.brainres.2020.147014 · Cited by 17
Tiwari, R. K., Moin, A., Rizvi, S. M. D., Shahid, S. M. A., & Bajpai, P. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-021-00696-6 · Cited by 19
Lee, S., Ju, I. G., Choi, Y., Park, S., & Oh, M. G. (2021) · Toxins · doi:10.3390/toxins13120898 · Cited by 17
Tabaa, M. M. E., Abo-Alazm, H. M., Shaalan, M., & Khedr, N. F. (2022) · Inflammopharmacology · doi:10.1007/s10787-022-00961-9 · Cited by 17
Human gut microbiota and Parkinson's disease
Pant, A., Bisht, K. S., Aggarwal, S., & Maiti, T. K. (2022) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2022.08.004 · Cited by 17
Modelling Alzheimer's disease using human brain organoids: current progress and challenges
Yanakiev, M., Soper, O., Berg, D. A., & Kang, E. (2022) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2022.40 · Cited by 17
Zhang, J., Zhu, F., Feng, E.-X., Wu, F. L., Fang, X., Tu, H., Wei, J., Wan, A.-L., & Chen, T. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105553 · Cited by 18
Teller, N., Chad, J. A., Wong, A. M., Gunraj, H., Ji, X., Goubran, M., Gilboa, A., Roudaia, E., Sekuler, A. B., Churchill, N. W., et al. (2023) · Human Brain Mapping · doi:10.1002/hbm.26322 · Cited by 16
Neuro‐HIV —New insights into pathogenesis and emerging therapeutic targets
Sviridov, D., & Bukrinsky, M. (2023) · The FASEB Journal · doi:10.1096/fj.202301239rr · Cited by 17
Helbing, D. L., Dommaschk, E.-M., Danyeli, L. V., Liepinsh, E., Refisch, A., Şen, Z. D., Zvejniece, L., Rocktäschel, T., Stabenow, L. K., Schiöth, H. B., et al. (2024) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-023-01734-3 · Cited by 17
Ratan, Y., Rajput, A., Pareek, A., Pareek, A., Jain, V. K., Sonia, S., Farooqui, Z., Kaur, R., & Singh, G. (2024) · Biomolecules · doi:10.3390/biom14010073 · Cited by 18
Wang, C., Cui, C., Xie, X., Chen, B., Feng, L., & Jiang, P. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06565-1 · Cited by 17
She, Y., Shao, C., Liu, Y., Huang, Y. S., Yang, J., & Wan, H. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1415445 · Cited by 18
Exploring the effect of gut microbiome on Alzheimer's disease
Pourahmad, R., Saleki, K., Zare, M., Aram, C., Farsani, A. S., Banazadeh, M., & Tafakhori, A. (2024) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2024.101776 · Cited by 20
Carmo, S. D., Kautzmann, M.-A. I., Bhattacharjee, S., Jun, B., Steinberg, C., Emmerson, J. T., Malcolm, J. C., Bonomo, Q., Bazan, N. G., & Cuello, A. C. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03184-7 · Cited by 18
Panda, S. P., Kesharwani, A., Singh, M., Kumar, S., Mayank, Mallick, S. P., & Guru, A. (2024) · Fitoterapia · doi:10.1016/j.fitote.2024.106173 · Cited by 17
Ming, Y., Zhao, P., Zhang, H., Zhang, Z., Huang, Z., Zhang, L., Sun, Y., & Li, X. (2024) · Inflammation · doi:10.1007/s10753-024-02155-7 · Cited by 18
Hennessy, M. B., Schiml, P. A., Berberich, K., Beasley, N. L., & Deak, T. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00314 · Cited by 17
Markousis‐Mavrogenis, G., Mitsikostas, D. D., Koutsogeorgopoulou, L. A., Dimitroulas, T., Katsifis, G. E., Argyriou, P., Apostolou, D., Velitsista, S., Vartela, V., Manolopoulou, D., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020447 · Cited by 17
Ojeda-Hernández, D. D., Gómez‐Pinedo, U., Hernández-Sapiéns, M. A., Canales-Aguirre, A. A., Espinosa‐Andrews, H., Matías‐Guiu, J., González‐García, Y., & Mateos‐Díaz, J. C. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111806 · Cited by 17
Na, S., Duan, X., Wang, R., Fan, Y., Xue, K., Tian, S., Yang, Z., Li, K., & Yue, J. (2021) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01758-7 · Cited by 17
Jin, M., Chen, D., Jin, Y.-H., Han, Y., Sun, H., & Kwon, T. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10402 · Cited by 17
Lecca, D., Hsueh, S., Luo, W., Tweedie, D., Kim, D. S., Baig, A. M., Vargesson, N., Kim, Y. K., Hwang, I., Kim, S., et al. (2023) · Journal of Biomedical Science · doi:10.1186/s12929-023-00907-5 · Cited by 17
The Power of Lifestyle Psychiatry: A New Approach to Mental Health
Merlo, G., & Sugden, S. G. (2025) · American Journal of Lifestyle Medicine · doi:10.1177/15598276251329915 · Cited by 16
Porcari, C., Cattaneo, S., Crippa, L., Simonato, M., & Bettegazzi, B. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1618330 · Cited by 16
Yu, X., Xiao, H. L. L. Y., Bao, S., Dong, Y., Dong, Z., Zhao, J., Wang, G., Meng, X., & Wang, F. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03629-7 · Cited by 16
TREM2 in neurodegeneration and diseases
Abdulkhaliq, A. A., Alasiri, G., Kim, B., Khan, J., Ajoolabady, A., Yousof, S. M., Ren, J., Tuomilehto, J., Borai, A., Alrfaei, B. M., et al. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03505-7 · Cited by 16
Focus on the Role of Klotho Protein in Neuro-Immune Interactions in HT-22 Cells Upon LPS Stimulation
Rusinek, K., Sołek, P., Tabęcka-Łonczyńska, A., Koziorowski, M., & Mytych, J. (2020) · Cells · doi:10.3390/cells9051231 · Cited by 16
Zhao, L., Cheng, N., Sun, B. N., Wang, S., Li, A., Wang, Z., Wang, Y., & Qi, F. (2020) · BioScience Trends · doi:10.5582/bst.2020.03262 · Cited by 17
Dynamic glial response and crosstalk in demyelination-remyelination and neurodegeneration processes
Shields, C. B., Cai, J., Chu, T., Shields, L. B. E., Zeng, W., Zhang, Y., Wang, Y., & Barnes, G. N. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.300975 · Cited by 21
Ünal, G. Ö., Aşçı, H., Erzurumlu, Y., İlhan, İ., Hasseyid, N., & Özmen, Ö. (2022) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2021.2025246 · Cited by 18
Wong, R. S.-Y. (2022) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-022-00525-2 · Cited by 18
Amodeo, G., Franchi, S., Galimberti, G., Comi, L., D’Agnelli, S., Baciarello, M., Bignami, E. G., & Sacerdote, P. (2022) · Biomedicines · doi:10.3390/biomedicines10112847 · Cited by 16
Sarubbo, F., Ramis, M. R., Tejada, S., Jiménez‐García, M., Esteban, S., Miralles, A., & Moranta, D. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105533 · Cited by 16
Cullen, P., & Sun, D. (2023) · Frontiers in Ophthalmology · doi:10.3389/fopht.2023.1217137 · Cited by 20
Ho, A., Ngala, B., Yamada, C., Garcia, C., Duarte, C. L., Akkaoui, J., Ciolac, D., Nusbaum, A., Kochen, W. R., Efremova, D., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115435 · Cited by 15
Chronic stress as an emerging risk factor for the development and progression of glioma
Yi, L., Lin, X., She, X., Gao, W. Q., & Wu, M. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000002976 · Cited by 16
Rodent Models of Alzheimer’s Disease: Past Misconceptions and Future Prospects
Collins, H. M., & Greenfield, S. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116222 · Cited by 21
The problem of residual pain in the assessment of rheumatoid arthritis activity
Motyl, G., Krupka, W. M., & Maślińska, M. (2024) · Reumatologia/Rheumatology · doi:10.5114/reum/189779 · Cited by 17
Rowe, C. J., Nwaolu, U., Martin, L., Huang, B. J., Mang, J., Salinas, D., Schlaff, C. D., Ghenbot, S. G., Lansford, J. L., Potter, B. K., et al. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03205-5 · Cited by 17
Arriaga-Gomez, E. A., Kline, J. M., Emanuel, E., Neamonitaki, N., Tenzin, Y., Zacheis, H., Pasha, D., Lim, J., Bush, S., Boo, B., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20215361 · Cited by 16
Sticozzi, C., Belmonte, G., Frosini, M., & Pessina, F. (2020) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01708-3 · Cited by 16
Quarta, A., Berneman, Z. N., & Ponsaerts, P. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.3ru0820-536r · Cited by 17
Waller, R., Narramore, R., Simpson, J. E., Heath, P. R., Verma, N., Tinsley, M., Barnes, J. R., Haris, H. T., Henderson, F. E., Matthews, F. E., et al. (2020) · Brain Pathology · doi:10.1111/bpa.12928 · Cited by 17
Preclinical Evaluation of TSPO and MAO-B PET Radiotracers in an LPS Model of Neuroinflammation
Narayanaswami, V., Tong, J., Schifani, C., Bloomfield, P. M., Dahl, K., & Vasdev, N. (2021) · PET Clinics · doi:10.1016/j.cpet.2020.12.003 · Cited by 16
Cathepsin B-A Neuronal Death Mediator in Alzheimer’s Disease Leading to Neurodegeneration
Singh, S. K., Sharma, A., Swetha, R., Bajad, N. G., Ganeshpurkar, A., Singh, R., & Kumar, A. (2022) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557522666220214095859 · Cited by 16
Neuroprotective Effects of Ecklonia cava in a Chronic Neuroinflammatory Disease Model
Jo, S.-L., Yang, H. J., Jeong, K. J., Lee, H. W., & Hong, E. (2023) · Nutrients · doi:10.3390/nu15082007 · Cited by 19
Wei, J., Liu, C., Qin, D., Ren, F., Duan, J., Chen, T., & Wu, A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102544 · Cited by 15
Natural drug delivery systems for the treatment of neurodegenerative diseases
Kaspute, G., Ramanavičius, A., & Prentice, U. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10286-9 · Cited by 16
Semendric, I., Barker, T. H., Haller, O. J., Pollock, D., Collins‐Praino, L. E., & Whittaker, A. L. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106283 · Cited by 15
Portelli, J., Wiers, C. E., Li, X., Deschaine, S. L., McDiarmid, G. R., Bermpohl, F., & Leggio, L. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107553 · Cited by 15
Frank, C. J., & McNay, E. C. (2021) · Journal of Neuroendocrinology · doi:10.1111/jne.13074 · Cited by 16
Shukla, M., Wongchitrat, P., & Govitrapong, P. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03530-2 · Cited by 12
Positron Emission Tomography of Neuroimmune Responses in Humans: Insights and Intricacies
Raval, N. R., Wetherill, R. R., Wiers, C. E., Dubroff, J. G., & Hillmer, A. T. (2022) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2022.08.008 · Cited by 15
Nheu, D., Ellen, O., Ye, S., Öztürk, E., Pagnin, M., Kertadjaja, S., Theotokis, P., Grigoriadis, N., McLean, C., & Petratos, S. (2022) · Cells · doi:10.3390/cells11233768 · Cited by 16
Syk inhibitors protect against microglia-mediated neuronal loss in culture
Birkle, T. J. Y., & Brown, G. C. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1120952 · Cited by 15
Xiao, L., Li, L., Huang, J., Luan, Y., Pan, J., Gai, Y., & Xu, Z. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109975 · Cited by 15
Mut-Arbona, P., & Sperlágh, B. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109541 · Cited by 16
Li, H., Ye, T., Liu, X., Guo, R., Yang, X., Li, Y., Qi, D., Wei, Y., Zhu, Y., Wen, L., et al. (2023) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2023.05.008 · Cited by 15
Cottam, N. C., Bamfo, T., Harrington, M. A., Charvet, C. J., Hekmatyar, K., Tulin, N., & Sun, J. (2023) · Brain Pathology · doi:10.1111/bpa.13162 · Cited by 15
Gao, J., Wang, N., Zong, F., Dong, J., Lin, Y., Zhang, H., & Zhang, F. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110389 · Cited by 15
Paradigm Shift: Multiple Potential Pathways to Neurodegenerative Dementia
Perna, A., Montine, K. S., White, L. R., Montine, T. J., & Cholerton, B. (2023) · Neurotherapeutics · doi:10.1007/s13311-023-01441-w · Cited by 16
Karnik, S. J., Margetts, T. J., Wang, H. S., Movilă, A., Oblak, A. L., Fehrenbacher, J. C., Kacena, M. A., & Plotkin, L. I. (2024) · Current Osteoporosis Reports · doi:10.1007/s11914-023-00847-x · Cited by 15
Rasool, A. E., Furlong, T. M., & Prasad, A. A. (2024) · Addiction Biology · doi:10.1111/adb.13374 · Cited by 14
Strengthening Neuroplasticity in Substance Use Recovery Through Lifestyle Intervention
Sugden, S. G., Merlo, G., & Manger, S. (2024) · American Journal of Lifestyle Medicine · doi:10.1177/15598276241242016 · Cited by 17
Deciphering the Enigma of Neuron-Glial Interactions in Neurological Disorders
Ahmad, S. R., Zeyaullah, M., AlShahrani, A. M., Dawria, A., Ali, H., Mohieldin, A., Altijani, A. A. G., Razi, U., Mehdi, M., Akram, S., et al. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2904142 · Cited by 15
Neuroprotective actions of norepinephrine in neurological diseases
Ghasemi, M., & Mehranfard, N. (2024) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-024-02999-w · Cited by 16
Naskar, R., Ghosh, A., Bhattacharya, R., & Chakraborty, S. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105859 · Cited by 16
Ortega, M. A., Fraile‐Μartinez, O., Montero, C. G., Díaz, R., López-González, L., Monserrat, J., Barrena-Blázquez, S., Álvarez-Mon, M. Á., Lahera, G., & Álvarez‐Mon, M. (2024) · Military Medical Research · doi:10.1186/s40779-024-00577-w · Cited by 21
Multi‐Targeting Phytochemicals for Alzheimer's Disease
Bhattacharya, R. S., Singh, R., Panghal, A., Thakur, A., Singh, L., Verma, R. K., Singh, C., Goyal, M., & Kumar, J. (2025) · Phytotherapy Research · doi:10.1002/ptr.8435 · Cited by 18
Halaris, A. E. (2018) · Future Neurology · doi:10.2217/fnl-2017-0039 · Cited by 14
Wolf, B., Brackhan, M., Bascuñana, P., Leiter, I., Langer, B. L. N., Roß, T. L., Bankstahl, J. P., & Bankstahl, M. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00834-5 · Cited by 15
Metadata
- Authors
- DiSabato, D. J., Quan, N., & Godbout, J. P.
- Affiliations
- The Ohio State University (US)
- Corresponding author
- Godbout, Jonathan P.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 2016-05-04
- Volume
- 139
- Issue
- S2
- Pages
- 136-153
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- PMC
- PMC5025335
- OpenAlex
- W2302151110
- Cited by
- 1,640
- References
- 202
- Citations by year
- 2026: 159 · 2025: 241 · 2024: 297 · 2023: 265 · 2022: 235 · 2021: 194 · 2020: 129 · 2019: 65 · 2018: 25 · 2017: 22 · 2016: 6
- FWCI
- 3.45
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Neurochemistry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01‐AG‐033028)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Keywords
- neuroinflammation, microglia, spinal cord injury, brain injury, stress, aging, functional recovery, central nervous system injury
- MeSH terms
- Aging, Animals, Brain, Humans, Inflammation, Spinal Cord, Microglia, Neurodegenerative Diseases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
