Melatonin prevents obesity through modulation of gut microbiota in mice

QIIME allows analysis of high-throughput community sequencing data

Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887

Search and clustering orders of magnitude faster than BLAST

Edgar, R. C. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq461 · Cited by 21,098

Metagenomic biomarker discovery and explanation

Segata, N., Izard, J., Waldron, L., Gevers, D., Miropolsky, L., Garrett, W. S., & Huttenhower, C. (2011) · Genome Biology · doi:10.1186/gb-2011-12-6-r60 · Cited by 16,192

FLASH: fast length adjustment of short reads to improve genome assemblies

Magoč, T., & Salzberg, S. L. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr507 · Cited by 15,366

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., AlMazroa, M. A., Amann, M., Anderson, H. R., Andrews, K. G., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61766-8 · Cited by 11,805

Human gut microbes associated with obesity

Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785

Obesity alters gut microbial ecology

Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176

The anti‐obesity and gut microbiota modulating effects of taxifolin in C57BL / 6J mice fed with a high‐fat diet

Su, H., Wang, W., Zheng, G., Yin, Z., Li, J., Chen, L., & Zhang, Q. (2021) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.11496 · Cited by 47

Intestinal Flora Mediates Antiobesity Effect of Rutin in High‐Fat‐Diet Mice

Yan, X., Zhai, Y., Zhou, W., Qiao, Y., Guan, L., Liu, H., Jiang, J., & Peng, L. (2022) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202100948 · Cited by 42

Update of Indoles: Promising molecules for ameliorating metabolic diseases

Hu, W., Yan, G., Ding, Q., Cai, J., Zhang, Z., Zhao, Z., Lei, H., & Zhu, Y. Z. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112957 · Cited by 42

Melatonin in Early Nutrition: Long-Term Effects on Cardiovascular System

Gombert, M., & Codoñer‐Franch, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136809 · Cited by 43

Elucidating the Regulatory Role of Melatonin in Brown, White, and Beige Adipocytes

Xu, Z., You, W., Liu, J., Wang, Y., & Shan, T. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz070 · Cited by 42

Diabetes and gut microbiota

Xi, Y., & Xu, P. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i10.1693 · Cited by 46

Effects of antibiotics consumption on the behavior of airborne antibiotic resistance genes in chicken farms

Song, L., Jiang, G., Wang, C., Ma, J., & Chen, H. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.129288 · Cited by 41

Melatonin relieves hepatic lipid dysmetabolism caused by aging via modifying the secondary bile acid pattern of gut microbes

Wei, D., Li, Y., Che, M., Li, C., Wu, Q., & Sun, C. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04412-0 · Cited by 41

Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet

Chen, L., Zhang, L., Wang, W., Qiu, W., Liu, L., Ning, A., Cao, J., Huang, M., & Zhong, M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0232972 · Cited by 41

Melatonin alleviates heat stress-induced spermatogenesis dysfunction in male dairy goats by regulating arachidonic acid metabolism mediated by remodeling the gut microbiota

Guo, X., Xu, J., Zhao, Y., Wang, J., Fu, T., Richard, M. L., Sokol, H., Wang, M., Li, Y., Liu, Y., et al. (2024) · Microbiome · doi:10.1186/s40168-024-01942-6 · Cited by 41

Circadian dysrhythmia-linked diabetes mellitus: Examining melatonin’s roles in prophylaxis and management

Onaolapo, A. Y., & Onaolapo, O. J. (2018) · World Journal of Diabetes · doi:10.4239/wjd.v9.i7.99 · Cited by 43

The effects of ammonia-N stress on immune parameters, antioxidant capacity, digestive function, and intestinal microflora of Chinese mitten crab, Eriocheir sinensis, and the protective effect of dietary supplement of melatonin

Yang, X., Shi, A., Song, Y., Niu, C. S., Yu, X., Shi, X., Pang, Y., Ma, X., & Cheng, Y. (2021) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2021.109127 · Cited by 39

Gut microbiota mediate melatonin signalling in association with type 2 diabetes

Huang, X., Qiu, Y., Gao, Y., Zhou, R., Hu, Q., He, Z., Lv, Y., Wang, X., Chen, W., Deng, Y., et al. (2022) · Diabetologia · doi:10.1007/s00125-022-05747-w · Cited by 40

Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota

Pan, S., Guo, Y., Hong, F., Xu, P., & Zhai, Y. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166281 · Cited by 37

Systematic review of the changes in the microbiome following spinal cord injury: animal and human evidence

Valido, E. M., Bertolo, A., Fränkl, G., Itodo, O. A., Pinheiro, T., Pannek, J., Kopp‐Heim, D., Glišić, M., & Stoyanov, J. V. (2022) · Spinal Cord · doi:10.1038/s41393-021-00737-y · Cited by 42

Melatonin attenuates microbiota dysbiosis of jejunum in short-term sleep deprived mice

Gao, T., Wang, Z., Cao, J., Dong, Y., & Chen, Y. (2020) · The Journal of Microbiology · doi:10.1007/s12275-020-0094-4 · Cited by 38

Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats

He, L., Li, J., Sun, M., Wang, X., Zhao, J., Zhang, W., Lv, G., Wang, Y., & Lin, Z. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128538 · Cited by 37

Chinese Propolis Prevents Obesity and Metabolism Syndromes Induced by a High Fat Diet and Accompanied by an Altered Gut Microbiota Structure in Mice

Zheng, Y., Wu, Y., Tao, L., Chen, X., Jones, T. J., Wang, K., & Hu, F. (2020) · Nutrients · doi:10.3390/nu12040959 · Cited by 39

Melatonin-Mediated Colonic Microbiota Metabolite Butyrate Prevents Acute Sleep Deprivation-Induced Colitis in Mice

Gao, T., Wang, Z., Dong, Y., Cao, J., & Chen, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111894 · Cited by 38

DBZ (Danshensu Bingpian Zhi), a Novel Natural Compound Derivative, Attenuates Atherosclerosis in Apolipoprotein E–Deficient Mice

Wang, J., Xu, P., Xie, X., Li, J., Wang, J., Wang, J., Hong, F., Li, J., Zhang, Y., Song, Y., et al. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.006297 · Cited by 35

Melatonin supplementation and anthropometric indicators of obesity: A systematic review and meta-analysis

Delpino, F. M., & Figueiredo, L. M. (2021) · Nutrition · doi:10.1016/j.nut.2021.111399 · Cited by 36

Health benefits of functional plant polysaccharides in metabolic syndrome: An overview

Yu, W., Zeng, D., Xiong, Y., Shan, S., Yang, X., Zhao, H., & Lu, W. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105154 · Cited by 36

Amelioration of metabolic disorders by a mushroom-derived polyphenols correlates with the reduction of Ruminococcaceae in gut of DIO mice

Sun, L. M., Bao, L., Phurbu, D., Qiao, S., Sun, S., Perma, Y., & Liu, H. (2021) · Food Science and Human Wellness · doi:10.1016/j.fshw.2021.04.006 · Cited by 36

Rebalancing glucolipid metabolism and gut microbiome dysbiosis by nitrate-dependent alleviation of high-fat diet-induced obesity

Ma, L., Hu, L., Jin, L., Wang, J., Li, X., Wang, W., Chang, S., Zhang, C., Wang, J., & Wang, S. (2020) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2020-001255 · Cited by 33

Intermittent Fasting Reshapes the Gut Microbiota and Metabolome and Reduces Weight Gain More Effectively Than Melatonin in Mice

Liu, J., Zhong, Y., Luo, X., Ma, Y., Liu, J., & Wang, H. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.784681 · Cited by 33

Polysaccharide from Flammulina velutipes residues protects mice from Pb poisoning by activating Akt/GSK3β/Nrf-2/HO-1 signaling pathway and modulating gut microbiota

Liu, Y., Li, H., Ren, P., Che, Y., Zhou, J., Wang, W., Yang, Y., & Guan, L. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123154 · Cited by 32

Microbial melatonin metabolism in the human intestine as a therapeutic target for dysbiosis and rhythm disorders

Zimmermann, P., Kurth, S., Pugin, B., & Bokulich, N. A. (2024) · npj Biofilms and Microbiomes · doi:10.1038/s41522-024-00605-6 · Cited by 38

The effects of antibiotics and melatonin on hepato-intestinal inflammation and gut microbial dysbiosis induced by a short-term high-fat diet consumption in rats

Yıldırım, A., Tamer, S. A., Sahin, D., Bağrıaçık, F., Kahraman, M. M., Onur, N. D., Çayırlı, Y. B., Çilingir‐Kaya, Ö. T., Aksu, B., Akdenız, E., et al. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519001466 · Cited by 33

Effects of the maternal gut microbiome and gut-placental axis on melatonin efficacy in alleviating cadmium-induced fetal growth restriction

Zhang, H., Liu, X., Zheng, Y., Zha, X., Elsabagh, M., Zhang, Y., Ma, Y., Loor, J. J., Wang, M., & Wang, H. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113550 · Cited by 32

Melatonin in energy control: Circadian time‐giver and homeostatic monitor

Challet, É., & Pévet, P. (2024) · Journal of Pineal Research · doi:10.1111/jpi.12961 · Cited by 34

Therapeutic potential of melatonin as a chronobiotic and cytoprotective agent in diabetes mellitus

Wajid, F., Poolacherla, R., Mim, F. K., Bangash, A., & Rutkofsky, I. H. (2020) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-020-00585-2 · Cited by 33

The protective effects of melatonin on survival, immune response, digestive enzymes activities and intestinal microbiota diversity in Chinese mitten crab (Eriocheir sinensis) exposed to glyphosate.

Song, Y.-M., Song, X.-Z., Wu, M.-Y., Pang, Y., Shi, A.-Y., Shi, X., Niu, C., Cheng, Y.-X., & Yang, X.-Z. (2020) · Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · doi:10.1016/j.cbpc.2020.108845 · Cited by 33

Antioxidant dietary fiber isolated from spent coffee ( Coffea arabica L.) grounds improves chronotype and circadian locomotor activity in young adults

Oseguera-Castro, K. Y., Madrid, J. A., Martínez Madrid, M. J., García, O. P., del Castillo, M. D., & Campos-Vega, R. (2019) · Food & Function · doi:10.1039/c9fo01021a · Cited by 31

The diet-microbiota axis: a key regulator of intestinal permeability in human health and disease

Tamang, R. L., Juritsch, A. F., Ahmad, R., Salomon, J., Dhawan, P., Ramer‐Tait, A. E., & Singh, A. B. (2022) · Tissue Barriers · doi:10.1080/21688370.2022.2077069 · Cited by 29

The protective mechanism of a novel polysaccharide from Lactobacillus-fermented Nostoc commune Vauch. on attenuating cadmium-induced kidney injury in mice

Li, H., Liu, Y., Zhou, J., Liu, S., Liu, Y., Yang, Y., Wang, W. “., Che, Y., Inam, M., & Guan, L. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.11.256 · Cited by 31

Are melatonin doses employed clinically adequate for melatonin-induced cytoprotection?

Cardinali, D. P. (2019) · Melatonin Research · doi:10.32794/mr11250025 · Cited by 29

High-Fat Diet Induced Gut Microbiota Alterations Associating With Ghrelin/Jak2/Stat3 Up-Regulation to Promote Benign Prostatic Hyperplasia Development

Gu, M., Liu, C., Yang, T., Zhan, M., Cai, Z., Chen, Y., Chen, Q., & Wang, Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.615928 · Cited by 30

Flavonoids from Rosa davurica Pall. fruits prevent high-fat diet-induced obesity and liver injury via modulation of the gut microbiota in mice

Shen, C., Hao, Y.-F., Hao, Z.-X., Liu, Q., Zhang, L., Jiang, C., & Jiang, J. (2021) · Food & Function · doi:10.1039/d1fo01373d · Cited by 29

Ranitidine and finasteride inhibit the synthesis and release of trimethylamine N-oxide and mitigates its cardiovascular and renal damage through modulating gut microbiota

Liu, J., Lai, L., Lin, J., Zheng, J., Nie, X., Zhu, X., Xue, J., & Liu, T. (2020) · International Journal of Biological Sciences · doi:10.7150/ijbs.40934 · Cited by 28

Fisetin regulates gut microbiota to decrease CCR9+/CXCR3+/CD4+ T-lymphocyte count and IL-12 secretion to alleviate premature ovarian failure in mice.

Lin, J., Nie, X., Xiong, Y., Gong, Z., Chen, J., Chen, C., Huang, Y., & Liu, T. (2020) · PubMed Central · Cited by 28

Chronic Systemic Low-Grade Inflammation and Modern Lifestyle: The Dark Role of Gut Microbiota on Related Diseases with a Focus on COVID-19 Pandemic

Mundula, T., Russo, E., Curini, L., Giudici, F., Piccioni, A., Franceschi, F., & Amedei, A. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220430131018 · Cited by 29

Ambient particulate matter (PM2.5) exposure contributes to neurodegeneration through the microbiome-gut-brain axis: Therapeutic role of melatonin

Panda, S. R., Chaudhari, V. B., Ahmed, S., Kwatra, M., Jala, A., Ponneganti, S., Pawar, S. D., Borkar, R. M., Sharma, P. K., & Naidu, V. G. M. (2023) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2023.104183 · Cited by 28

Deciphering the mechanism of jujube vinegar on hyperlipoidemia through gut microbiome based on 16S rRNA, BugBase analysis, and the stamp analysis of KEEG

Duan, G., & Li, L. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1160069 · Cited by 32

Harnessing immunomodulation to combat sarcopenia: current insights and possible approaches

Zhang, N., Zhai, L., Wong, R. M. Y., Cui, C., Law, S. W., Chow, S. K., Goodman, S. B., & Cheung, W. (2024) · Immunity & Ageing · doi:10.1186/s12979-024-00458-9 · Cited by 32

Towards a comprehensive etiopathogenetic and pathophysiological theory of multiple sclerosis

Tobore, T. O. (2019) · International Journal of Neuroscience · doi:10.1080/00207454.2019.1677648 · Cited by 31

Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury

Gao, T., Wang, Z., Cao, J., Dong, Y., & Chen, Y. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.106041 · Cited by 27

The Role of Prenatal Melatonin in the Regulation of Childhood Obesity

Иванов, Д. О., Evsyukova, I. I., Mazzoccoli, G., Anderson, G., Polyakova, V. O., Kvetnoy, I. M., Carbone, A., & Nasyrov, R. A. (2020) · Biology · doi:10.3390/biology9040072 · Cited by 27

Gut microbiota from mice with cerebral ischemia-reperfusion injury affects the brain in healthy mice

Wang, H., Ren, S., Lv, H., & Cao, L. (2021) · Aging · doi:10.18632/aging.202763 · Cited by 27

Comparison of gut microbial communities, free amino acids or fatty acids contents in the muscle of wild Aristichthys nobilis from Xinlicheng reservoir and Chagan lake

Lu, Y., Zhang, P., Li, W., Liu, J., Shang, X., Cheng, Y., & Li, Y. (2022) · BMC Microbiology · doi:10.1186/s12866-022-02440-1 · Cited by 25

Safety Evaluation and In vivo Strain-Specific Functionality of Bacillus Strains Isolated from Korean Traditional Fermented Foods

Park, H., Lee, M.-K., Jeong, D., Park, S., Ji, Y., Todorov, S. D., & Holzapfel, W. H. (2020) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-020-09672-5 · Cited by 25

Er-Chen Decoction Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Rats through Remodeling Gut Microbiota and Regulating the Serum Metabolism

Miao, J., Guo, L., Cui, H., Wang, L., Zhu, B., Lei, J., Li, P., Jia, J., & Zhang, Z. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/6221340 · Cited by 25

Cardiometabolic comorbidities and complications of obesity and chronic kidney disease (CKD)

Ali, M. M., Parveen, S., Williams, V. R., Dons, R. F., & Uwaifo, G. I. (2024) · Journal of Clinical & Translational Endocrinology · doi:10.1016/j.jcte.2024.100341 · Cited by 31

Obesity-associated alterations in cardiac connexin-43 and PKC signaling are attenuated by melatonin and omega-3 fatty acids in female rats

Beňová, T. E., Viczenczová, C., Bačová, B. S., Knezl, V., Dosenko, V., Rauchová, H., Zeman, M., Reiter, R. J., & Tribulová, N. (2018) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-018-3463-0 · Cited by 25

Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota

Wang, W., Zhong, M., Yu, T., Chen, L., Shi, L., Zong, J., & Wang, S. (2020) · Nutrition & Metabolism · doi:10.1186/s12986-020-00442-2 · Cited by 24

Bovine serum albumin aggravates macrophage M1 activation and kidney injury in heterozygous Klotho-deficient mice via the gut microbiota-immune axis

Lai, L., Li, Y., Liu, J., Luo, L., Tang, J., Xue, J., & Liu, T. (2021) · International Journal of Biological Sciences · doi:10.7150/ijbs.56424 · Cited by 24

Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application

Vaghari‐Tabari, M., Moein, S., Alipourian, A., Qujeq, D., Malakoti, F., Alemi, F., Yousefi, B., & Khazaie, S. (2022) · Biochimie · doi:10.1016/j.biochi.2022.12.007 · Cited by 24

Effects of dietary melatonin on growth performance, antioxidant capacity, and nonspecific immunity in crayfish, Cherax destructor

Yang, Y., Xu, W., Du, X., Ye, Y., Tian, J., Li, Y., Jiang, Q., & Zhao, Y. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.108846 · Cited by 26

The role of melatonin supplement in metabolic syndrome

Bahrami, M., Cheraghpour, M., Jafarirad, S., Alavinejad, P., & Cheraghian, B. (2019) · Nutrition & Food Science · doi:10.1108/nfs-01-2019-0018 · Cited by 24

Distribution and Difference of Gastrointestinal Flora in Sheep with Different Body Mass Index

Cheng, J., Wang, W., Zhang, D., Zhang, Y., Song, Q., Li, X., Zhao, Y., Xu, D., Zhao, L., Li, W., et al. (2022) · Animals · doi:10.3390/ani12070880 · Cited by 23

Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep

Sun, Y., Sun, P. G., Hu, Y., Shan, L., Geng, Q., Gong, Y., Fan, H., Zhang, T., & Zhou, Y. (2022) · BMC Biology · doi:10.1186/s12915-022-01326-y · Cited by 23

Intestinal microbiota and melatonin in the treatment of secondary injury and complications after spinal cord injury

Zhang, Y.-W., Lang, R., Guo, S., Luo, X., Li, H., Liu, C., Dong, W., Bao, C., & Yu, Y. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.981772 · Cited by 22

Melatonin and probiotics ameliorate nanoplastics-induced hematopoietic injury by modulating the gut microbiota-metabolism

Zhang, L., Jing, J., Lin, H., Liu, Z., Wang, J., Zhang, W., & Gao, A. (2022) · Nano Research · doi:10.1007/s12274-022-5032-9 · Cited by 23

Role of melatonin in murine “restraint stress”-induced dysfunction of colonic microbiota

Lin, R., Wang, Z., Cao, J., Gao, T., Dong, Y., & Chen, Y. (2021) · The Journal of Microbiology · doi:10.1007/s12275-021-0305-7 · Cited by 22

Pear pomace soluble dietary fiber ameliorates the negative effects of high-fat diet in mice by regulating the gut microbiota and associated metabolites

Ji, Y., Mao, K., Gao, J., Chitrakar, B., Sadiq, F. A., Wang, Z., Wu, J., Xu, C., & Sang, Y. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1025511 · Cited by 23

Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism

Liu, X., Cui, Y., Zhang, Y., Guo, X., Meng, Y., Wang, X., Qiu, B., Li, X., Liu, W., & Zhang, D. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113949 · Cited by 22

Flammulina velutipes residue Polysaccharide Alleviates Immunosuppression and Intestinal Injury by Modulating Gut Microbiota and Associated Metabolites

Yang, Y., Zhang, Y., Zhang, W., Lu, K., Wang, L., Liu, Y., Du, L., Yang, J., Guan, L., & Ma, H. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c12105 · Cited by 21

The orchestra of human bacteriome by hormones

Luqman, A. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106125 · Cited by 22

Tree Nut Consumption and Adipose Tissue Mass: Mechanisms of Action

Tindall, A. M., Petersen, K. S., Lamendella, R., Shearer, G. C., Murray‐Kolb, L. E., Proctor, D. N., & Kris‐Etherton, P. M. (2018) · Current Developments in Nutrition · doi:10.1093/cdn/nzy069 · Cited by 21

Dietary L-Arginine or N-Carbamylglutamate Alleviates Colonic Barrier Injury, Oxidative Stress, and Inflammation by Modulation of Intestinal Microbiota in Intrauterine Growth-Retarded Suckling Lambs

Zhang, H., Zheng, Y., Zha, X., Ma, Y., Liu, X., Elsabagh, M., Wang, H., & Wang, M. (2022) · Antioxidants · doi:10.3390/antiox11112251 · Cited by 20

Melatonin: A potential adjuvant therapy for septic myopathy

Liu, Y., Wang, D., Li, T., Xu, L., Li, Z., Bai, X., Tang, M., & Wang, Y.-C. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114209 · Cited by 20

Melatonin potentiates the effects of metformin on glucose metabolism and food intake in high‐fat‐fed rats

Dantas-Ferreira, R., Raingard, H., Dumont, S., Schuster, C., Lemaître, B. J., Pévet, P., & Challet, É. (2018) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.39 · Cited by 19

Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet

Guo, Y., Huang, C., Liu, L., Fu, X.-Y., Lu, Y., Zheng, J., Mei, Q., Huang, Z., Fan, J., Lu, L., et al. (2019) · Mediators of Inflammation · doi:10.1155/2019/8474523 · Cited by 20

Towards a Comprehensive Theory of Non-Cancer Acute and Chronic Pain Management: The Critical Role of Reactive Oxygen and Nitrogen Species in Pain, and Opioid Dependence, Addiction, Hyperalgesia, and Tolerance

Tobore, T. O. (2021) · Advances in Redox Research · doi:10.1016/j.arres.2021.100003 · Cited by 20

Melatonin Ameliorates Age‐Related Sarcopenia via the Gut–Muscle Axis Mediated by Serum Lipopolysaccharide and Metabolites

Zhou, L., Yang, Y., Mou, L., Xia, X., Liu, M., Xu, L., Liu, R., Liu, J., Zhang, H., Ao, X., et al. (2025) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13722 · Cited by 19

Essential Roles of PPARs in Lipid Metabolism during Mycobacterial Infection

Tanigawa, K., Luo, Y., Kawashima, A., Kiriya, M., Nakamura, Y., Karasawa, K., & Suzuki, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147597 · Cited by 22

The gut microbiome and obstructive sleep apnea syndrome in children

Liu, W., Du, Q., Zhang, H., & Han, D. (2022) · Sleep Medicine · doi:10.1016/j.sleep.2022.09.022 · Cited by 21

Mixed conjugated linoleic acid sex‐dependently reverses high‐fat diet‐induced insulin resistance via the gut‐adipose axis

Li, H., Zhuang, P., Zhang, Y., Shou, Q., Lu, Y., Wang, G., Qiu, J., Wang, J., He, L., Chen, J., et al. (2021) · The FASEB Journal · doi:10.1096/fj.202002161rr · Cited by 19

Acute melatonin administration improves exercise tolerance and the metabolic recovery after exhaustive effort

Faria, V. S., Pejon, T. M. M., Gobatto, C. A., de Araújo, G. G., Cornachione, A. S., & Beck, W. R. (2021) · Scientific Reports · doi:10.1038/s41598-021-97364-7 · Cited by 20

The Protective Effect of Auricularia cornea var. Li. Polysaccharide on Alcoholic Liver Disease and Its Effect on Intestinal Microbiota

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Melatonin-mediated corrective changes in gut microbiota of experimentally chronodisrupted C57BL/6J mice

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Exosome prospects in the diagnosis and treatment of non-alcoholic fatty liver disease

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The potential therapeutic approaches targeting gut health in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a narrative review

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Protective Effects of Melatonin in High-Fat Diet-Induced Hepatic Steatosis via Decreased Intestinal Lipid Absorption and Hepatic Cholesterol Synthesis

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Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

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Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high‐fat diet‐fed mice

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The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome

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Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short‐Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies

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