One patient out of four with newly diagnosed erectile dysfunction is a young man—worrisome picture from the everyday clinical practice
Abstract
INTRODUCTION: Erectile dysfunction (ED) is a common complaint in men over 40 years of age, and prevalence rates increase throughout the aging period. Prevalence and risk factors of ED among young men have been scantly analyzed. AIM: Assessing sociodemographic and clinical characteristics of young men (defined as ≤ 40 years) seeking first medical help for new onset ED as their primary sexual disorder. METHODS: Complete sociodemographic and clinical data from 439 consecutive patients were analyzed. Health-significant comorbidities were scored with the Charlson Comorbidity Index (CCI). Patients completed the International Index of Erectile Function (IIEF). MAIN OUTCOME MEASURE: Descriptive statistics tested sociodemographic and clinical differences between ED patients ≤ 40 years and >40 years. RESULTS: New onset ED as the primary disorder was found in 114 (26%) men ≤ 40 years (mean [standard deviation [SD]] age: 32.4 [6.0]; range: 17-40 years). Patients ≤ 40 years had a lower rate of comorbid conditions (CCI = 0 in 90.4% vs. 58.3%; χ(2) , 39.12; P < 0.001), a lower mean body mass index value (P = 0.005), and a higher mean circulating total testosterone level (P = 0.005) as compared with those >40 years. Younger ED patients more frequently showed habit of cigarette smoking and use of illicit drug, as compared with older men (all P ≤ 0.02). Premature ejaculation was more comorbid in younger men, whereas Peyronie's disease was prevalent in the older group (all P = 0.03). At IIEF, severe ED rates were found in 48.8% younger men and 40% older men, respectively (P > 0.05). Similarly, rates of mild, mild-to-moderate, and moderate ED were not significantly different between the two groups. CONCLUSIONS: This exploratory analysis showed that one in four patients seeking first medical help for new onset ED was younger than 40 years. Almost half of the young men suffered from severe ED, with comparable rates in older patients. Overall, younger men differed from older individuals in terms of both clinical and sociodemographic parameters.
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In that Italian study, younger patients more frequently showed habits of cigarette smoking and use of illicit drugs.
“They more frequently showed habits of cigarette smoking and use of illicit drugs.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
In an Italian study, 26% of 439 patients first presenting with a diagnosis of erectile dysfunction were no older than 40 years.
“In an Italian study, 64 26% of 439 patients fi rst presenting with a diagnosis of ED were no older than 40 years.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
In that Italian study, the mean age of these younger patients was 32.4 years.
“The mean age of these men was 32.4 years.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
In that Italian study, younger patients had a lower rate of comorbid conditions.
“These younger patients had a lower rate of comorbid conditions, a lower mean body mass index, and higher mean total testosterone, but a higher rate of PE.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
In that Italian study, younger patients had a lower mean body mass index.
“These younger patients had a lower rate of comorbid conditions, a lower mean body mass index, and higher mean total testosterone, but a higher rate of PE.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
In that Italian study, younger patients had higher mean total testosterone.
“These younger patients had a lower rate of comorbid conditions, a lower mean body mass index, and higher mean total testosterone, but a higher rate of PE.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
In that Italian study, younger patients had a higher rate of premature ejaculation.
“These younger patients had a lower rate of comorbid conditions, a lower mean body mass index, and higher mean total testosterone, but a higher rate of PE.”
From Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015 (2016) · cites this paper as [64]
Cites
Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987) · Journal of Chronic Diseases · doi:10.1016/0021-9681(87)90171-8 · Cited by 49,742 · see citing works
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961 · see citing works
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,452 · see citing works
Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997) · Urology · doi:10.1016/s0090-4295(97)00238-0 · Cited by 5,849 · see citing works
Sexual Dysfunction in the United States: Prevalence and Predictors
Laumann, E. O., Paik, A., & Rosen, R. C. (1999) · JAMA · doi:10.1001/jama.281.6.537 · Cited by 5,119 · see citing works
Impotence and Its Medical and Psychosocial Correlates: Results of the Massachusetts Male Aging Study
Feldman, H. A., Goldstein, I., Hatzichristou, D. G., Krane, R. J., & McKinlay, J. B. (1994) · Journal of Urology · doi:10.1016/s0022-5347(17)34871-1 · Cited by 5,074 · see citing works
(1993) · JAMA · doi:10.1001/jama.1993.03510010089036 · Cited by 1,629 · see citing works
Epidemiology of erectile dysfunction: results of the ‘Cologne Male Survey’
Braun, M., Wassmer, G., Klotz, T. H., Reifenrath, B., Mathers, M., & Engelmann, U. (2000) · International journal of impotence research · doi:10.1038/sj.ijir.3900622 · Cited by 981 · see citing works
(1999) · doi:10.1016/s0090-4295(99)00099-0 · Cited by 897 · see citing works
Montorsi, F., Briganti, A., Salonia, A., Rigatti, P., Margonato, A., Macchi, A., Galli, S., Ravagnani, P. M., & Montorsi, P. (2003) · European Urology · doi:10.1016/s0302-2838(03)00305-1 · Cited by 598 · see citing works
Martín‐Morales, A., Sánchez-Cruz, J. J., de Tejada, I. S., Rodriguez-Vela, L., Jiménez-Cruz, J. F., & BURGOS-RODRIGUEZ, R. (2001) · The Journal of Urology · doi:10.1016/s0022-5347(05)65986-1 · Cited by 551 · see citing works
Corona, G., Lee, D. M., Forti, G., O'Connor, D. B., Maggi, M., O’Neill, T. W., Pendleton, N., Bártfai, G., Boonen, S., Casanueva, F. F., et al. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01601.x · Cited by 545 · see citing works
Nicolosi, A., Moreira, E. D., Shirai, M., Ismail Bin Mohd Tambi, M., & Glasser, D. B. (2003) · Urology · doi:10.1016/s0090-4295(02)02102-7 · Cited by 499 · see citing works
Anatomy, Physiology, and Pathophysiology of Erectile Dysfunction
Gratzke, C., Angulo, J., Chitaley, K., Dai, Y.-T., Kim, N. N., Paick, J.-S., Simonsen, U., Ückert, S., Wespes, E., Andersson, K. E., et al. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01624.x · Cited by 470 · see citing works
Erectile Dysfunction and Risk of Cardiovascular Disease
Dong, J.-Y., Zhang, Y., & Qin, L.-Q. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.06.024 · Cited by 450 · see citing works
Prevalence and Risk Factors for Erectile Dysfunction in 2869 Men Using a Validated Questionnaire
PONHOLZER, A., TEMML, C., MOCK, K., MARSZALEK, M., OBERMAYR, R., & MADERSBACHER, S. (2005) · European Urology · doi:10.1016/j.eururo.2004.08.017 · Cited by 361 · see citing works
Prevalence of erectile dysfunction: a systematic review of population-based studies
Prins, J. T. H., Blanker, M. H., Bohnen, A. M., Thomas, S., & Bosch, J. L. H. R. (2002) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900905 · Cited by 278 · see citing works
Gacci, M., Eardley, I., Giuliano, F., Hatzichristou, D., Kaplan, S., Maggi, M., McVary, K., Mirone, V., Porst, H., & Roehrborn, C. (2011) · European Urology · doi:10.1016/j.eururo.2011.06.037 · Cited by 274 · see citing works
Sexual problems in healthy and depressed persons
Angst, J. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199807006-00001 · Cited by 273 · see citing works
Frequency and Determinants of Erectile Dysfunction in Italy
Parazzini, F., Fabris, F. M., Bortolotti, A., ograve, A. C., Chatenoud, L., Colli, E., Landoni, M., Lavezzari, M., Turchi, P., Sessa, A., et al. (2000) · European Urology · doi:10.1159/000020098 · Cited by 235 · see citing works
Kupelian, V. A., Shabsigh, R., de Araújo, A. B., O’Donnell, A. B., & McKinlay, J. B. (2006) · The Journal of Urology · doi:10.1016/s0022-5347(06)00503-9 · Cited by 183 · see citing works
(1994) · doi:10.1093/oxfordjournals.aje.a117189 · Cited by 154 · see citing works
Chew, K.-K., Finn, J., Stuckey, B. G. A., Gibson, N., Sanfilippo, F. M., Bremner, A., Thompson, P. L., HOBBS, M. S. T., & Jamrozik, K. D. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01576.x · Cited by 148 · see citing works
Schouten, B., Bohnen, A. M., Bosch, J. L. H. R., Bernsen, R. M. D., Deckers, J. W., Dohle, G. R., & Thomas, S. (2007) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901604 · Cited by 146 · see citing works
Salonia, A., Castagna, G., Saccà, A., Ferrari, M., Umberto Capitanio, A., Castiglione, F., Rocchini, L., Briganti, A., Rigatti, P., & Montorsi, F. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02869.x · Cited by 136 · see citing works
Epidemiology of Erectile Dysfunction: the Role of Medical Comorbidities and Lifestyle Factors
Rosen, R. C., Wing, R. R., Schneider, S., & Gendrano, N. (2005) · Urologic Clinics of North America · doi:10.1016/j.ucl.2005.08.004 · Cited by 121 · see citing works
Sexual dysfunctions among young men: Prevalence and associated factors
Mialon, A., Berchtold, A., Michaud, P.-A., Gmel, G., & Suris, J.-C. (2012) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2012.01.008 · Cited by 120 · see citing works
Guo, W., Liao, C., Zou, Y.-G., Li, F. Y., Li, T., Zhou, Q.-Z., Cao, Y., & Mao, X. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.01792.x · Cited by 116 · see citing works
Modifying Risk Factors to Prevent and Treat Erectile Dysfunction
Glina, S., Sharlip, I. D., & Hellstrom, W. J. G. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02816.x · Cited by 101 · see citing works
Roth, A., Kalter‐Lftbovhx, O., Kerbis, Y., Tekenbaum‐Koren, E., Chen, J., Sobol, T., & Raz, I. (2003) · Clinical Cardiology · doi:10.1002/clc.4960260106 · Cited by 95 · see citing works
Aversa, A., Rossi, F., Francomano, D., Bruzziches, R., Bertone, C., Santiemma, V., & Spera, G. (2008) · International Journal of Impotence Research · doi:10.1038/ijir.2008.43 · Cited by 85 · see citing works
Erectile dysfunction and correlated factors in Brazilian men aged 18–40 years
Martins, F. G., & Abdo, C. H. N. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01542.x · Cited by 74 · see citing works
Impact of Cannabis Use on Male Sexual Health
Shamloul, R. M., & Bella, A. J. (2011) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.02198.x · Cited by 64 · see citing works
Prevalence and predictors of sexual problems in men aged 75-95 years: a population-based study.
Hyde, Z., Flicker, L., Hankey, G., Almeida, O., McCaul, K., Chubb, S. A. P., & Yeap, B. (2012) · Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2011.02565.x · Cited by 64 · see citing works
Harte, C. B., & Meston, C. M. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00637.x · Cited by 59 · see citing works
Gades, N. M., Jacobson, D. J., McGree, M. E., St. Sauver, J. L., Lieber, M. M., Nehra, A., Girman, C. J., & Jacobsen, S. J. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01374.x · Cited by 47 · see citing works
Brotons, F. B., Campos, J. C., Gonzalez-Correales, R., Martín‐Morales, A., Moncada, I., & Pomerol, J. M. (2004) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901240 · Cited by 37 · see citing works
Deveci, S., O’Brien, K., Ahmed, A., Parker, M., Guhring, P., & Mulhall, J. P. (2008) · British Journal of Urology · doi:10.1111/j.1464-410x.2008.07610.x · Cited by 36 · see citing works
Management of Erectile Dysfunction in General Practice
Berardis, G. D., Pellegrini, F., Franciosi, M., Pamparana, F., Morelli, P., Tognoni, G., & Nicolucci, A. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2008.01093.x · Cited by 31 · see citing works
Akré, C., Michaud, P., & Surı́s, J.-C. (2010) · Swiss Medical Weekly · doi:10.4414/smw.2010.12968 · Cited by 31 · see citing works
Pescatori, E., Giammusso, B., Piubello, G., Gentile, V., & Farina, F. P. (2007) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00460.x · Cited by 19 · see citing works
Correlates of PDE5i Use Among Subjects with Erectile Dysfunction in Two Population-Based Surveys
Travison, T. G., Hall, S. A., Fisher, W. A., de Araújo, A. B., Rosen, R. C., McKinlay, J. B., & Sand, M. S. (2011) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2011.02423.x · Cited by 16 · see citing works
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Yafi, F. A., Jenkins, L., Albersen, M., Corona, G., Isidori, A. M., Goldfarb, S., Maggi, M., Nelson, C. J., Parish, S., Salonia, A., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.3 · Cited by 853 · see citing works
McCabe, M. P., Sharlip, I. D., Lewis, R., Atalla, E., Balon, R., Fisher, A. D., Laumann, E., Lee, S. W., & Segraves, R. T. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2015.12.034 · Cited by 577 · see citing works
The Emperor Has No Clothes: A Review of the ‘Pornography Addiction’ Model
Ley, D., Prause, N., & Finn, P. (2014) · Current Sexual Health Reports · doi:10.1007/s11930-014-0016-8 · Cited by 272 · see citing works
Is internet pornography causing sexual dysfunctions? A review with clinical reports
Park, B., Wilson, G., Berger, J., Christman, M., Reina, B., Bishop, F., Klam, W., & Doan, A. (2016) · Behavioral Sciences · doi:10.3390/bs6030017 · Cited by 187 · see citing works
Current diagnosis and management of erectile dysfunction
McMahon, C. G. (2019) · The Medical Journal of Australia · doi:10.5694/mja2.50167 · Cited by 169 · see citing works
Erectile dysfunction in fit and healthy young men: psychological or pathological?
Rastrelli, G., & Maggi, M. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2016.09.06 · Cited by 123 · see citing works
Landripet, I., & Štulhofer, A. (2015) · The Journal of Sexual Medicine · doi:10.1111/jsm.12853 · Cited by 110 · see citing works
Aging related erectile dysfunction—potential mechanism to halt or delay its onset
Ferrini, M. G., González-Cadavid, N. F., & Rajfer, J. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2016.11.18 · Cited by 90 · see citing works
The obstetrical dilemma hypothesis: there's life in the old dog yet
Haeusler, M., Grunstra, N. D. S., Martin, R. D., Krenn, V. A., Fornai, C., & Webb, N. M. (2021) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12744 · Cited by 88 · see citing works
The Psychology of Human Sexuality
Lehmiller, J. J. (2013) · Cited by 89 · see citing works
O'Sullivan, L. F., Brotto, L. A., Byers, E. S., Majerovich, J. A., & Wuest, J. A. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12419 · Cited by 87 · see citing works
Calzo, J. P., Austin, S. B., Charlton, B. M., Missmer, S. A., Kathrins, M. N., Gaskins, A. J., & Chavarro, J. E. (2020) · The Journal of Urology · doi:10.1097/ju.0000000000001367 · Cited by 87 · see citing works
Bronner, G., & Ben-Zion, I. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12501 · Cited by 48 · see citing works
Male Sexual Function and Smoking
Biebel, M. G., Burnett, A. L. “., & Sadeghi‐Nejad, H. (2016) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2016.05.001 · Cited by 48 · see citing works
Jiang, T., Osadchiy, V., Mills, J. N., & Eleswarapu, S. V. (2020) · Urology · doi:10.1016/j.urology.2020.04.100 · Cited by 46 · see citing works
Pozzi, E., Fallara, G., Capogrosso, P., Boeri, L., Belladelli, F., Corsini, C., da Costa, A. G., Candela, L., Cignoli, D., Cazzaniga, W., et al. (2022) · Andrology · doi:10.1111/andr.13212 · Cited by 43 · see citing works
Sexual Dysfunction in Patients With Chronic Gastrointestinal and Liver Diseases: A neglected Issue
Romano, L., Granata, L., Fusco, F., Napolitano, L., Cerbone, R., Priadko, K., Sciorio, C., Mirone, V., & Romano, M. (2021) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2021.02.002 · Cited by 41 · see citing works
The Temporal Association of Depression and Anxiety in Young Men with Erectile Dysfunction
Manalo, T. A., Biermann, H., Patil, D. H., & Mehta, A. (2021) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2021.11.011 · Cited by 39 · see citing works
Shahinyan, R. H., Amighi, A., Carey, A. N., Yoffe, D. A., Hodge, D. C., Pollard, M. E., Nork, J., Mills, J. N., & Eleswarapu, S. V. (2020) · Urology · doi:10.1016/j.urology.2020.03.067 · Cited by 38 · see citing works
The first‐generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue
Zucchi, A., Costantini, E., Scroppo, F. I., Silvani, M., Kopa, Z., Illiano, E., Petrillo, M. G., Cari, L., & Nocentini, G. (2019) · Andrology · doi:10.1111/andr.12683 · Cited by 36 · see citing works
Ortaç, M., Özmez, A., Çilesiz, N. C., Demirelli, E., & Kadıoğlu, A. (2021) · Andrology · doi:10.1111/andr.13007 · Cited by 36 · see citing works
Problematic pornography use: narrative review and a preliminary model
Binnie, J., & Reavey, P. (2019) · Sexual & Relationship Therapy · doi:10.1080/14681994.2019.1694142 · Cited by 34 · see citing works
Significance of blood lipid parameters as effective markers for arteriogenic erectile dysfunction
Li, M., Ma, Z., Zhang, X., Guo, L., & Yuan, M. (2020) · Andrology · doi:10.1111/andr.12776 · Cited by 32 · see citing works
New approaches to the design and discovery of therapies to prevent erectile dysfunction
Toque, H. A., & Caldwell, R. W. (2014) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2014.949234 · Cited by 32 · see citing works
Tinahones, F. J., Fernández-García, J., Molina‐Vega, M., Asenjo‐Plaza, M., Banderas-Donaire, M. J., Hernández-Ollero, M., Rodríguez-Moreno, S., Álvarez‐Millán, J. J., Cabezas-Sánchez, P., Cardona, F., et al. (2019) · Asian Journal of Andrology · doi:10.4103/aja.aja_106_19 · Cited by 30 · see citing works
The relationship between the gut microbiota, benign prostatic hyperplasia, and erectile dysfunction
Russo, G. I., Bongiorno, D., Bonomo, C., Musso, N., Stefani, S., Sokolakis, I., Hatzichristodoulou, G., Falcone, M., Cai, T., Smarrazzo, F., et al. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-022-00569-1 · Cited by 31 · see citing works
Potential causes of male and female infertility in Qatar
Zauner, G., & Girardi, G. (2020) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2020.103173 · Cited by 28 · see citing works
The pseudoscience behind public health crisis legislation
Ley, D. J. (2018) · Porn Studies · doi:10.1080/23268743.2018.1435400 · Cited by 28 · see citing works
Erectile Dysfunction in Men on the Rise: Is There a Link with Endocrine Disrupting Chemicals?
Cripps, S. M., Mattiske, D. M., & Pask, A. J. (2021) · Sexual Development · doi:10.1159/000516600 · Cited by 27 · see citing works
Bilal, A., & Abbasi, N. U. H. (2020) · Sexual Medicine · doi:10.1016/j.esxm.2020.05.005 · Cited by 26 · see citing works
Pathological Roles of Reactive Oxygen Species in Male Reproduction
Chakraborty, S., & Roychoudhury, S. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-89340-8_3 · Cited by 25 · see citing works
Mykoniatis, I., Grammatikopoulou, M. G., Bouras, E., Karampasi, E., Tsionga, A., Kogias, A., Vakalopoulos, I., Haidich, A., & Chourdakis, M. (2018) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2017.12.008 · Cited by 25 · see citing works
Pozzi, E., Capogrosso, P., Chierigo, F., Pederzoli, F., Ventimiglia, E., Boeri, L., Frego, N., Moretti, D., Dehò, F., Montorsi, F., et al. (2018) · European Urology Focus · doi:10.1016/j.euf.2018.10.003 · Cited by 25 · see citing works
Stigmatization as a Barrier to Urologic Care: A Review
Foster, P., Luebke, M., Razzak, A. N., Anderson, D. J., Hasoon, J. J., Viswanath, O., Kaye, A. D., & Urits, I. (2023) · Health Psychology Research · doi:10.52965/001c.84273 · Cited by 23 · see citing works
Trends in reported male sexual dysfunction over the past decade: an evolving landscape
Pozzi, E., Capogrosso, P., Boeri, L., Cazzaniga, W., Matloob, R., Ventimiglia, E., Oreggia, D., Schifano, N., Candela, L., Abbate, C., et al. (2020) · International Journal of Impotence Research · doi:10.1038/s41443-020-0324-7 · Cited by 25 · see citing works
Short Sleep Duration and Erectile Dysfunction: A Review of the Literature
Zhang, F., Xiong, Y., Qin, F., & Yuan, J. (2022) · Nature and Science of Sleep · doi:10.2147/nss.s375571 · Cited by 23 · see citing works
Calogero, A. E., Burgio, G., Condorelli, R. A., Cannarella, R., & Vignera, S. L. (2018) · The Aging Male · doi:10.1080/13685538.2018.1430758 · Cited by 22 · see citing works
Does underestimated penile size impact erectile function in healthy men?
Sanches, . C. F., Laranja, W. W., Alonso, J. C. C., Rejowski, R. F., Simões, F. A., & Reis, L. O. (2018) · International Journal of Impotence Research · doi:10.1038/s41443-018-0039-1 · Cited by 22 · see citing works
Should we tailor the clinical management of erectile dysfunction according to different ages?
Capogrosso, P., Ventimiglia, E., Boeri, L., Pozzi, E., Chierigo, F., Schifano, N., Abbate, C., Matloob, R., Montorsi, F., & Salonia, A. (2019) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.03.405 · Cited by 21 · see citing works
Erectile Dysfunction in Adolescents and Young Adults
Pantazis, A., Franco, I., & GITLIN, J. S. (2024) · Current Urology Reports · doi:10.1007/s11934-024-01213-9 · Cited by 21 · see citing works
von Büren, M., Rodler, S., Wiesenhütter, I., Schröder, F. A. Y. N., Büchner, A., Stief, C. G., Gratzke, C., Wülfing, C., & von Büren, J. (2021) · European Urology Focus · doi:10.1016/j.euf.2021.04.019 · Cited by 20 · see citing works
Erectile dysfunction in young patients is a proxy of overall men's health status
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A treatment algorithm for healthy young men with erectile dysfunction
Wiggins, A., Tsambarlis, P. N., Abdelsayed, G., & Levine, L. A. (2019) · BJU International · doi:10.1111/bju.14458 · Cited by 18 · see citing works
Salonia, A., Clementi, M. C., Ventimiglia, E., Colicchia, M., Capogrosso, P., Castiglione, F., Castagna, G., Boeri, L., Suardi, N. R., Cantiello, F., et al. (2014) · Andrology · doi:10.1111/j.2047-2927.2014.00236.x · Cited by 18 · see citing works
Results from an online survey investigating ED patients' insights and treatment expectations
Burri, A. V., & Porst, H. (2015) · International Journal of Impotence Research · doi:10.1038/ijir.2015.14 · Cited by 17 · see citing works
Bilal, A., & Abbasi, N. U. H. (2021) · Sexual Medicine · doi:10.1016/j.esxm.2021.100464 · Cited by 17 · see citing works
Assessment of sexual dysfunction in patients with inflammatory bowel disease
Szydlarska, D., Jakubowska, A., & Rydzewska, G. M. (2019) · Gastroenterology Review · doi:10.5114/pg.2019.85893 · Cited by 17 · see citing works
Chen, H., Li, Z., Li, X., Yang, Y., Dai, Y., Xie, Z., Xiao, J., Liu, X., Yang, L., Shi, C., et al. (2022) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2022.06.009 · Cited by 16 · see citing works
Asexuality Development among Middle Aged and Older Men
Huang, Y., Chen, B., Ping, P., Wang, H., Hu, K., Yang, H., Zhang, T., Feng, T., Jin, Y., Han, Y.-F., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092794 · Cited by 16 · see citing works
Tang, Z., Song, J., Yu, Z., Cui, K., Ruan, Y., Wang, T., Yang, J., Wang, S., & Liu, J. (2019) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.07.003 · Cited by 16 · see citing works
Burgio, G., Giammusso, B., Calogero, A. E., Mollaioli, D., Condorelli, R. A., Jannini, E. A., & Vignera, S. L. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8101679 · Cited by 16 · see citing works
Sexual Dysfunctions in the Internet Era
Mollaioli, D., Sansone, A., Romanelli, F., & Jannini, E. A. (2018) · Trends in andrology and sexual medicine · doi:10.1007/978-3-319-68306-5_15 · Cited by 15 · see citing works
Ma, W., Qin, M., Cui, T., Zhang, X., Ke, Z.-H., Pan, Z.-K., Gao, Y., & Liu, B. (2021) · Translational Andrology and Urology · doi:10.21037/tau-20-1056 · Cited by 15 · see citing works
Jiang, W., Xiong, L., Yang, B., Li, W., Zhang, J., Zhou, Q., Wu, Q., Li, T., Zhang, C., Zhang, M., et al. (2016) · Scientific Reports · doi:10.1038/srep26647 · Cited by 14 · see citing works
Estrogenic endocrine disruptor exposure directly impacts erectile function
Cripps, S. M., Marshall, S. A., Mattiske, D. M., Ingham, R. Y., & Pask, A. J. (2024) · Communications Biology · doi:10.1038/s42003-024-06048-1 · Cited by 13 · see citing works
Chen, Z., Liu, J., Cui, K., Luan, Y., Tang, Z., Li, C., Wang, T., & Wang, S. (2019) · Asian Journal of Andrology · doi:10.4103/aja.aja_111_18 · Cited by 13 · see citing works
van Renterghem, K., & Dehò, F. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-022-00547-7 · Cited by 12 · see citing works
Capogrosso, P., Ventimiglia, E., Boeri, L., Serino, A., Russo, A., Croce, G. L., Umberto Capitanio, A., Dehò, F., Montorsi, F., & Salonia, A. (2017) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2017.1288567 · Cited by 12 · see citing works
Data on the utilization of treatment modalities for ED in Taiwan in the era of PDE5 inhibitors
Tsai, W.-K., & Jiann, B.-P. (2014) · International Journal of Impotence Research · doi:10.1038/ijir.2013.53 · Cited by 12 · see citing works
A syndrome of erectile dysfunction in young men?
Reed-Maldonado, A., & Lue, T. (2016) · Translational Andrology and Urology · doi:10.21037/tau.2016.03.02 · Cited by 10 · see citing works
Analysis of patient education materials on TikTok for erectile dysfunction treatment
Shah, Y., Beiriger, J., Mehta, S. D., & Cohen, S. D. (2023) · International Journal of Impotence Research · doi:10.1038/s41443-023-00726-0 · Cited by 11 · see citing works
Schneider, D., Loeb, C. A., Brevik, A., El‐Khatib, F. M., Jenkins, L. C., & Yafi, F. A. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-022-00567-3 · Cited by 11 · see citing works
Huang, Y., Chen, B., Yao, F., Chen, S., Ouyang, B., Deng, C., & Huang, Y. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12460 · Cited by 11 · see citing works
Avanafil - a further step to tailoring patient needs and expectations
Boeri, L., Capogrosso, P., Ventimiglia, E., Serino, A., Croce, G. L., Russo, A., Damiano, R., Montorsi, F., & Salonia, A. (2016) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2016.1195261 · Cited by 11 · see citing works
Risk factors for hypogonadism in young men with erectile dysfunction
Huang, I.-S., Mazur, D. J., Kahn, B. E., Keeter, M. K., Desai, A. S., Lewis, K., Tatem, A. J., Hehemann, M. C., Brannigan, R. E., & Bennett, N. (2019) · Journal of the Chinese Medical Association · doi:10.1097/jcma.0000000000000099 · Cited by 10 · see citing works
Panken, E. J., Fantus, R. J., Chang, C., Kashanian, J. A., Helfand, B. T., Brannigan, R. E., Bennett, N., & Halpern, J. A. (2020) · Urology · doi:10.1016/j.urology.2020.09.016 · Cited by 9 · see citing works
Chen, S. X., Yao, F.-J., Xz, S., Wu, R.-P., Huang, Y.-P., Zheng, F.-F., Yang, Q.-Y., Han, D.-Y., Xie, M.-Q., Ding, M., et al. (2016) · International Journal of Impotence Research · doi:10.1038/ijir.2016.30 · Cited by 9 · see citing works
Bravo‐Balado, A., Trujillo, C. G., Caicedo, J. I., García, S., Azuero, J., Rondón, M., & Plata, M. (2021) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2021.02.009 · Cited by 8 · see citing works
Kızılay, F., Kalemci, S., Şimşir, A., & Altay, B. (2019) · Andrologia · doi:10.1111/and.13495 · Cited by 8 · see citing works
Buchholz, V. N., Mühle, C., Factors, C. S. O. S. U. R., Kornhuber, J., & Lenz, B. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.517411 · Cited by 8 · see citing works
Significance of detailed hematological parameters as markers of arteriogenic erectile dysfunction
Liu, G., Zhang, Y., Zhang, W., Wu, X., Huang, H., Jiang, H., & Zhang, X. (2022) · Andrology · doi:10.1111/andr.13283 · Cited by 8 · see citing works
Silva, A. C., Silva, C., & Morgado, A. (2023) · Sexual Medicine · doi:10.1093/sexmed/qfad009 · Cited by 8 · see citing works
Favilla, V., Russo, G. I., Reale, G., Leone, S., Castelli, T., Vignera, S. L., Condorelli, R. A., Calogero, A. E., Cimino, S., & Morgia, G. (2015) · International Journal of Impotence Research · doi:10.1038/ijir.2015.15 · Cited by 8 · see citing works
Análisis del grado de disfunción eréctil en adultos jóvenes de Tijuana, México
Jáuregui-Vélez, D. I., Bermúdez-Villalpando, V. I., Vidal-Solorzano, L. C., Castillo-Montes, M. A., Ochoa, M. C., & Leyva, D. H. R. (2022) · Atención Familiar · doi:10.22201/fm.14058871p.2023.1.83864 · Cited by 7 · see citing works
Davis, A., & Reisman, Y. (2020) · International Journal of Impotence Research · doi:10.1038/s41443-019-0227-7 · Cited by 7 · see citing works
Characteristics of men who use direct-to-consumer men’s health telemedicine services
Hudnall, M. T., Ambulkar, S. S., Lai, J. D., Pham, M. N., Fantus, R. J., Keeter, M. K., Wren, J. M., Bennett, N., Brannigan, R. E., & Halpern, J. A. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-022-00635-8 · Cited by 7 · see citing works
Time-effect of penile color duplex Doppler ultrasound for diagnosing vascular erectile dysfunction
Wang, J., Wang, J., Liu, Q., Jia, H., Zhang, C., Liu, C., Sun, L., Shu, D., Xia, J., Guo, J., et al. (2020) · Medical Ultrasonography · doi:10.11152/mu-2059 · Cited by 6 · see citing works
Zhuravleva, Z. D., Johansson, A., & Jern, P. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.10.017 · Cited by 6 · see citing works
Heart Rate Variability and Erectile Function in Younger Men: A Pilot Study
Costa, R. M., Mangia, P., Pestana, J. O. M., & Costa, D. (2021) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-020-09499-4 · Cited by 6 · see citing works
Phenomenological and existential contributions to the study of erectile dysfunction
Suijker, C. A., van Mazijk, C., Keijzer, F., & Meijer, B. (2021) · Medicine Health Care and Philosophy · doi:10.1007/s11019-021-10029-0 · Cited by 6 · see citing works
Tripathi, A., Kumar, D., Kar, S. K., Dalal, P., & Nischal, A. (2021) · Journal of Psychosexual Health · doi:10.1177/26318318211031104 · Cited by 6 · see citing works
Pozzi, E., Corsini, C., Bertini, A., Belladelli, F., Raffo, M., Negri, F., Cattafi, F., Cilio, S., Boeri, L., Capogrosso, P., et al. (2024) · The Journal of Sexual Medicine · doi:10.1093/jsxmed/qdae064 · Cited by 6 · see citing works
Cycling and men’s health: A worldwide survey in association the Global Cycling Network
Koupparis, A. J., Mehmi, A., Ravà, M. S., Kearley, S., Aning, J. J., Rowe, E., & Richardson, S. (2020) · Journal of Clinical Urology · doi:10.1177/2051415820915389 · Cited by 6 · see citing works
Medical Treatment of Erectile Dysfunction: Too Many Medical Prescriptions?
Capogrosso, P., Ventimiglia, E., Oreggia, D., Salonia, A., & Montorsi, F. (2017) · Urologia Journal · doi:10.5301/uj.5000250 · Cited by 6 · see citing works
Wang, D., Wang, S., Li, Y., Liu, C., Li, Y., Zhang, Y., & Su, Y. (2023) · Patient Preference and Adherence · doi:10.2147/ppa.s399776 · Cited by 5 · see citing works
Semen Analysis in “Urology-Naïve” Patients: A Chance of Uroandrological Screening in Young Males
Puliatti, S., Toso, S., Ticonosco, M., Rabito, S., Sighinolfi, M. C., Ferrari, R., Rochira, V., Santi, D., Trenti, T., Navarra, M., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12113803 · Cited by 5 · see citing works
Diagnosis and management of erectile dysfunction
Bromby, A., Modgil, V., & Pearce, I. (2021) · Trends in Urology & Men s Health · doi:10.1002/tre.817 · Cited by 5 · see citing works
Ke, M.-H., Bao, B., Ke, Z., Ma, W., Guo, J., Zhang, L., Wen, H., Ma, L.-R., Fan, G., & Liu, B. (2023) · Endocrine · doi:10.1007/s12020-023-03653-8 · Cited by 4 · see citing works
Progress in erectile dysfunction therapy through drug delivery system
Shitole, M., Dugam, S., Tade, R., Desai, N., & Nangare, S. (2020) · The Thai Journal of Pharmaceutical Sciences · doi:10.56808/3027-7922.2442 · Cited by 4 · see citing works
Jones, A. C., Johnson, N. C., Wenglein, S., & Elshershaby, S. T. (2019) · Journal of Marital and Family Therapy · doi:10.1111/jmft.12344 · Cited by 4 · see citing works
Conservative Non-surgical Options for Erectile Dysfunction
Alonso-Isa, M., García‐Gómez, B., Ginel, I. G., Encina, C. G.-R., González, M. D. P. C., Medina‐Polo, J., Rojo, E. G., & Otero, J. (2022) · Current Urology Reports · doi:10.1007/s11934-022-01137-2 · Cited by 4 · see citing works
The impact of asexual trait and porn addiction in a young men healthy cohort
Russo, G. I., Campisi, D., Mauro, M. D., Falcone, M., Cocci, A., Cito, G., Verze, P., Capogrosso, P., Fode, M. M., Cacciamani, G. E., et al. (2021) · Andrologia · doi:10.1111/and.14142 · Cited by 4 · see citing works
Montgomery, J., Madsen, C., Leroux, T. C., & Koehlmoos, T. P. (2018) · International Journal of Impotence Research · doi:10.1038/s41443-018-0037-3 · Cited by 4 · see citing works
Men’s Feminist Identification and Reported Use of Prescription Erectile Dysfunction Medication
Silva, T. J., & Fetner, T. (2022) · The Journal of Sex Research · doi:10.1080/00224499.2022.2029810 · Cited by 3 · see citing works
Introduction, Epidemiology and Etiology of Sexual Dysfunctions in Men and Women
Carvalho, J., & García‐Gómez, B. (2022) · Management of urology · doi:10.1007/978-3-031-12049-7_1 · Cited by 3 · see citing works
Sadiq, N., & Warsi, J. (2025) · Cureus · doi:10.7759/cureus.76928 · Cited by 2 · see citing works
Boeri, L., Graps, G., Zino, E., Zago, A., Puma, A. L., Ciamarra, F., Cimmino, A., Parolin, V., Piccoli, M., Gadda, F., et al. (2025) · International Journal of Impotence Research · doi:10.1038/s41443-025-01019-4 · Cited by 2 · see citing works
Vaginismus treatment: a systematic review and meta-analysis of contemporary therapeutic approaches
Zülfikaroğlu, E. (2025) · The Journal of Sexual Medicine · doi:10.1093/jsxmed/qdaf295 · Cited by 2 · see citing works
Imaging of the Three-Piece Inflatable Penile Prosthesis
Aswani, Y. (2026) · Radiographics · doi:10.1148/rg.250175 · Cited by 2 · see citing works
Lower Urinary Tract Symptoms (LUTS) and Sexual Function and Dysfunction
Konstantinidis, C., Eleftheropoulos, I., & Karafotias, A. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.86827 · Cited by 2 · see citing works
- Authors
- Capogrosso, P., Colicchia, M., Ventimiglia, E., Castagna, G., Clementi, M. C., Suardi, N., Castiglione, F., Briganti, A., Cantiello, F., Damiano, R., Montorsi, F., & Salonia, A.
- Affiliations
- Vita-Salute San Raffaele University (IT)
- Magna Graecia University (IT)
- Corresponding author
- Salonia, Andrea
- ORCID
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-07-01
- Volume
- 10
- Issue
- 7
- Pages
- 1833-1841
- ISSN
- 1743-6095 (ISSN-L)
- 1743-6109
- OpenAlex
- W1925214338
- Cited by
- 167
- References
- 43
- Citations by year
- 2026: 15 · 2025: 12 · 2024: 10 · 2023: 12 · 2022: 19 · 2021: 20 · 2020: 14 · 2019: 15 · 2018: 15 · 2017: 8 · 2016: 11 · 2015: 5 · 2014: 9 · 2013: 2
- FWCI
- 6.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- The Journal of Sexual Medicine (publishedVersion)
- PubMed (publishedVersion)
- IrInSubria (University of Insubria) (submittedVersion)
- Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
- Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Keywords
- erectile dysfunction, young men, age differences, comorbidities, Charlson Comorbidity Index, body mass index, testosterone, cigarette smoking, illicit drug use, premature ejaculation, Peyronie's disease, International Index of Erectile Function, ED severity
- MeSH terms
- Adolescent, Adult, Humans, Erectile Dysfunction, Italy, Male, Penile Induration, Risk Factors, Testosterone, Comorbidity, Prevalence, Young Adult, Premature Ejaculation
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