CoChat
Sign Up
Cited by 42Hormonal and reproductive studiesSexual function and dysfunction studiesMenopause: Health Impacts and Treatments

Patient satisfaction with testosterone replacement therapies: the reasons behind the choices

Open access
Kovac, Jason R., Rajanahally, Saneal, Smith, Ryan P., Coward, Robert M., Lamb, Dolores J., Lipshultz, Larry I.·2014·The Journal of Sexual Medicine
DOI 10.1111/jsm.12369PMC PMC3946859
Open this paper in CoChat — free account

Abstract

Introduction: Testosterone replacement therapy (TRT) for male hypogonadism is rapidly gaining popularity and acceptance. Options include gels, injections, and implantable subcutaneous pellets. Aims: The aim of this study was to determine rates of patient satisfaction and reasons for patient preferences in hypogonadal men on TRT. Methods: An anonymous, prospective survey was distributed to men presenting for TRT at an academic urology clinic. The survey was organized into multiple domains including patient satisfaction and treatment motivation. Main Outcome Measures: Patient satisfaction responses obtained via anonymous survey. Results: Average patient age was 49 ± 0.7 years (n = 382). Injectable testosterone was chosen by 53%, gel-based regimens by 31%, and pellets by 17%. Overall, 70% of patients were satisfied with their TRT and 14% reported dissatisfaction. Satisfaction rates were similar between gels (68%), injections (73%), and implantable pellets (70%). Doctor recommendation was the sole significant reason for patients preferring gel-based TRT (66% vs. 37% injection users vs. 31% pellet users). Injectable TRT was favored because of lower cost (35% vs. 21% gel users vs. 19% pellet users). Pellets were favored for ease of use (64% vs. 44% injection users vs. 43% gel users) and convenience (58% vs. 26% injection users vs. 19% gel users). Pellets had increased rates of satisfaction within the first 12 months. Improvements in concentration and mood occurred at higher percentages in satisfied patients. Conclusions: Patients are satisfied with TRT. Lower costs are important to patients on injections. Convenience and ease of use are central in choosing pellet therapy. Men on TRT should be questioned about mood and concentration because these factors exhibited the greatest improvements in satisfied patients.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/jsm.12369

Cites

59 of 59 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • T therapy in males with central hypogonadism reduces fat mass and increases fat-free mass.

    “T therapy in males with central hypogonadism reduces fat mass and increases fat-free mass (132,135,140,148,149).”

    From Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline (2016) · cites this paper as [148]

    The Introduction reports improvements in body weight and waist circumference with testosterone replacement therapy, and the Results report patient-perceived improvement in muscle mass. Neither passage establishes reduced fat mass and increased fat-free mass specifically in men with central hypogonadism; the paper's mention of hypogonadotropic hypogonadism concerns secondary sexual characteristics instead. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Kovac, J. R., Rajanahally, S., Smith, R. P., Coward, R. M., Lamb, D. J., & Lipshultz, L. I.
Affiliations
Baylor College of Medicine (US)
Corresponding author
Kovac, Jason R.
ORCID
Venue
The Journal of Sexual Medicine
Publisher
Oxford University Press (OUP)
Published
2014-02-01
Volume
11
Issue
2
Pages
553-562
ISSN
  • 1743-6095 (ISSN-L)
  • 1743-6109
DOI
10.1111/jsm.12369
PMC
PMC3946859
OpenAlex
W1557237798
Cited by
42
References
59
Citations by year
2026: 3 · 2025: 1 · 2024: 1 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 2 · 2018: 1 · 2017: 5 · 2016: 7 · 2015: 5 · 2014: 3
FWCI
3.94
Type
journal article
Language
en
Open access
Licence
academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations
  • The Journal of Sexual Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (K12, HD073917-01)
  • Eunice Kennedy Shriver NICHD (P01HD36289, 1R01DK078121)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords
testosterone replacement therapy, male hypogonadism, patient satisfaction, treatment preferences, injectable testosterone, testosterone gel, treatment costs, convenience, mood improvement, concentration
MeSH terms
Drug Implants, Gels, Humans, Hypogonadism, Male, Middle Aged, Prospective Studies, Testosterone, Patient Satisfaction, Hormone Replacement Therapy

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review