The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Review: The role of vitamin D in nervous system health and disease
Abstract
Vitamin D and its metabolites have pleomorphic roles in both nervous system health and disease. Animal models have been paramount in contributing to our knowledge and understanding of the consequences of vitamin D deficiency on brain development and its implications for adult psychiatric and neurological diseases. The conflation of in vitro, ex vivo, and animal model data provide compelling evidence that vitamin D has a crucial role in proliferation, differentiation, neurotrophism, neuroprotection, neurotransmission, and neuroplasticity. Vitamin D exerts its biological function not only by influencing cellular processes directly, but also by influencing gene expression through vitamin D response elements. This review highlights the epidemiological, neuropathological, experimental and molecular genetic evidence implicating vitamin D as a candidate in influencing susceptibility to a number of psychiatric and neurological diseases. The strength of evidence varies for schizophrenia, autism, P arkinson's disease, amyotrophic lateral sclerosis, A lzheimer's disease, and is especially strong for multiple sclerosis.
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Cites
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Cited by
Autism Spectrum Disorder and low vitamin D at birth: A sibling control study
Fernell, E., Bejerot, S., Westerlund, J., Miniscalco, C., Simila, H., Eyles, D., Gillberg, C., & Humble, M. B. (2015) · Molecular Autism · doi:10.1186/2040-2392-6-3 · Cited by 160
Clinical improvement following vitamin D3 supplementation in Autism Spectrum Disorder
Feng, J., Shan, L., Du, L., Wang, B., Li, H., Wang, W., Wang, T., Dong, H., Yue, X., Xu, Z., et al. (2017) · Nutritional Neuroscience · doi:10.1080/1028415x.2015.1123847 · Cited by 141
Muscular effects of vitamin D in young athletes and non-athletes and in the elderly
Koundourakis, N. E., Avgoustinaki, P. D., Malliaraki, N., & Margioris, A. N. (2016) · Hormones · doi:10.14310/horm.2002.1705 · Cited by 109
Vitamin D status and Parkinson's disease: a systematic review and meta-analysis
Lv, Z., Qi, H., Wang, L., Fan, X., Han, F., Wang, H., & Bi, S. (2014) · Neurological Sciences · doi:10.1007/s10072-014-1821-6 · Cited by 69
Vitamin D and Neurotrophin Levels and Their Impact on the Symptoms of Schizophrenia
Peitl, V., Silić, A., Orlović, I., Vidrih, B., Crnković, D., & Karlović, D. (2020) · Neuropsychobiology · doi:10.1159/000504577 · Cited by 22
Luthra, N. S., Clow, A., & Corcos, D. M. (2022) · Brain Sciences · doi:10.3390/brainsci12121695 · Cited by 20
Li, Y., & Freedman, R. (2020) · Pediatric Investigation · doi:10.1002/ped4.12199 · Cited by 13
Metadata
- Authors
- DeLuca, G. C., Kimball, S. M., Kolasinski, J., Ramagopalan, S. V., & Ebers, G. C.
- Venue
- Neuropathology and Applied Neurobiology
- Publisher
- Wiley
- Published
- 2013-07-09
- Volume
- 39
- Issue
- 5
- Pages
- 458-484
- ISSN
- 0305-1846 (ISSN-L)
- 1365-2990
- OpenAlex
- W2150135472
- Cited by
- 326
- References
- 25
- FWCI
- 17.79
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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