Review: Astrocytes in Alzheimer's disease and other age‐associated dementias: a supporting player with a central role

The Hallmarks of Aging

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982

Astrocyte-endothelial interactions at the blood-brain barrier

Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

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A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129

Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders

Zlokovic, B. V. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3114 · Cited by 2,969

Tripartite synapses: glia, the unacknowledged partner

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Genomic analysis of reactive astrogliosis

Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., & Barres, B. A. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6221-11.2012 · Cited by 2,404

Brain energy metabolism: focus on Astrocyte-neuron metabolic cooperation

Bélanger, M., Allaman, I., & Magistretti, P. J. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.016 · Cited by 2,313

Microglial TREM2 Mitigates Inflammatory Responses and Neuronal Apoptosis in Angiotensin II-Induced Hypertension in Middle-Aged Mice

Xu, X., Du, L., Jiang, J., Yang, M., Wang, Z., Wang, Y., Tang, T., Fu, X., & Hao, J. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.716917 · Cited by 25

The role of astrocytes in prion-like mechanisms of neurodegeneration

Smethurst, P., Franklin, H., Clarke, B. E., Sidle, K. C. L., & Patani, R. (2021) · Brain · doi:10.1093/brain/awab366 · Cited by 25

Uncovering Plaque-Glia Niches in Human Alzheimer’s Disease Brains Using Spatial Transcriptomics

Avey, D. R., Ng, B., Vialle, R. A., Kearns, N. A., de Paiva Lopes, K., Iatrou, A., De Tissera, S., Vyas, H., Saunders, D. M., Flood, D. J., et al. (2024) · doi:10.1101/2024.09.05.611566 · Cited by 24

Glia-derived exosomes: Promising therapeutic targets

Li, H., Luo, Y., Zhu, L., Hua, W., Zhang, Y., Zhang, H., Zhang, L., Li, Z., Xing, P., Zhang, Y., et al. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116951 · Cited by 23

NVP-BEZ235 (Dactolisib) Has Protective Effects in a Transgenic Mouse Model of Alzheimer’s Disease

Bellozi, P. M. Q., Gomes, G. F., de Oliveira, L. R., Olmo, I. G., Vieira, É. L. M., Ribeiro, F. M., Fiebich, B. L., & de Oliveira, A. C. P. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01345 · Cited by 22

Astrocyte Activation, but not Microglia, Is Associated with the Experimental Mouse Model of Schizophrenia Induced by Chronic Ketamine

Wei, Y., Xiao, L., Fan, W., Zou, J., Yang, H., Liu, B., Ye, Y., Wen, D., & Liao, L. (2022) · Journal of Molecular Neuroscience · doi:10.1007/s12031-022-02046-2 · Cited by 23

Real‐world applicability of glial fibrillary acidic protein and neurofilament light chain in Alzheimer's disease

Parvizi, T., König, T., Wurm, R., Silvaieh, S., Altmann, P., Klotz, S., Rommer, P. S., Furtner, J., Regelsberger, G., Lehrner, J., et al. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.887498 · Cited by 25

Restoring microglial and astroglial homeostasis using DNA immunization in a down Syndrome mouse model.

Illouz, T., Madar, R., Biragyn, A., & Okun, E. (2019) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.10.004 · Cited by 22

Necroptotic astrocytes induced neuronal apoptosis partially through EVs-derived pro-BDNF

Chen, Z., Tang, H., Kang, J., Chen, Z., Li, Y., Fan, Q.-Y., Zhang, L., Song, Y.-H., Zhang, G., & Fan, H. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.09.014 · Cited by 22

Alzheimer’s disease is an inherent, natural part of human brain aging: an integrated perspective

Ferrer, I. (2022) · Free Neuropathology · doi:10.17879/freeneuropathology-2022-3806 · Cited by 25

Serum and cerebrospinal fluid neurofilament light chain and glial fibrillary acid protein levels in early and advanced stages of cerebral amyloid Angiopathy

Rasing, I., Voigt, S., Koemans, E. A., de Kort, A. M., van Harten, T. W., van Etten, E. S., van Zwet, E. W., Stoops, E., François, C., Kuiperij, H. B., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01457-0 · Cited by 21

Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer’s disease in APP/PS1 mouse

Wang, S., Zhu, T., Ni, W., Zhou, C., Zhou, H., Lin, L., Hu, Y., Sun, X., Han, J., Zhou, Y., et al. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01186-w · Cited by 20

Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons

Hatakeyama, N., Unekawa, M., Murata, J., 冨田, 裕., Suzuki, N., Nakahara, J., Takuwa, H., Kanno, I., Matsui, K., Tanaka, K. F., et al. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211010355 · Cited by 22

Overcoming undesirable hERG affinity by incorporating fluorine atoms: A case of MAO-B inhibitors derived from 1 H-pyrrolo-[3,2-c]quinolines

Grychowska, K., Olejarz‐Maciej, A., Blicharz-Futera, K., Pietruś, W., Karcz, T. P., Kurczab, R., Koczurkiewicz, P., Doroż-Płonka, A., Latacz, G., Keeri, A. R., et al. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114329 · Cited by 19

A novel strategy for delivering N iemann‐ P ick type C2 proteins across the blood–brain barrier using the brain endothelial‐specific AAV‐BR1 virus

Rasmussen, C. L. M., Hede, E., Routhe, L. G., Körbelin, J., Helgudóttir, S. S., Thomsen, L. B., Schwaninger, M., Burkhart, A., & Moos, T. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15621 · Cited by 20

Local volume fraction distributions of axons, astrocytes, and myelin in deep subcortical white matter

Coelho, S., Pozo, J. M., Costantini, M., Highley, J. R., Mozumder, M., Simpson, J. E., Ince, P. G., & Frangi, A. F. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.06.040 · Cited by 23

Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion

Boggia, R., Turrini, F., Roggeri, A., Olivero, G., Cisani, F., Bonfiglio, T., Summa, M., Grilli, M., Caviglioli, G., Alfei, S., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103631 · Cited by 19

Ishige okamurae Attenuates Neuroinflammation and Cognitive Deficits in Mice Intracerebroventricularly Injected with LPS via Regulating TLR-4/MyD88-Dependent Pathways

Kwon, O.-Y., & Lee, S. H. (2022) · Antioxidants · doi:10.3390/antiox12010078 · Cited by 19

Are cytoskeleton changes observed in astrocytes functionally linked to aging?

Villablanca, C., Vidal, R. L., & González-Billault, C. E. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.03.007 · Cited by 19

The role of astrocytes in generating circadian rhythmicity in health and disease

Costa, R., & Montagnese, S. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15312 · Cited by 18

The p53 Family in Brain Disease

Agostini, M., Melino, G., & Bernassola, F. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7302 · Cited by 19

Analog of kynurenic acid decreases tau pathology by modulating astrogliosis in rat model for tauopathy

Majerová, P., Olešová, D., Golisova, G., Buralova, M., Michalicová, A., Vegh, J., Piešťanský, J., Bhide, M. R., Hanes, J., & Kováč, A. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113257 · Cited by 17

The role of ADAM10 in astrocytes: Implications for Alzheimer’s disease

Elsworthy, R. J., Hill, E. J., Dunleavy, C., & Aldred, S. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1056507 · Cited by 17

Alzheimer’s Disease from the Amyloidogenic Theory to the Puzzling Crossroads between Vascular, Metabolic and Energetic Maladaptive Plasticity

Cerasuolo, M., Papa, M., Colangelo, A. M., & Rizzo, M. R. (2023) · Biomedicines · doi:10.3390/biomedicines11030861 · Cited by 18

Single-Cell RNA-Sequencing in Astrocyte Development, Heterogeneity, and Disease

Gao, M.-Y., Wang, J., He, J. M., Gao, R., Zhang, Y., & Li, X. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01397-7 · Cited by 21

Resident brain neural precursor cells develop age-dependent loss of therapeutic functions in Alzheimer's mice

Fainstein, N., Dan-Goor, N., & Ben‐Hur, T. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.07.020 · Cited by 17

From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimers Disease

Alarcón‐Espósito, J., Mallea, M., & Rodríguez-Lavado, J. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200914155951 · Cited by 19

Inhibition of PI3K/Akt/mTOR signaling by NDRG2 contributes to neuronal apoptosis and autophagy in ischemic stroke.

Wang, Y., Wang, B., Liu, Y.-Y., Guo, Y.-H., Lu, H., & Liu, X.-Q. (2023) · Journal of Stroke & Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2023.106984 · Cited by 14

The effect of glutamate-induced excitotoxicity on DNA methylation in astrocytes in a new in vitro neuron-astrocyte-endothelium co-culture system

Zhao, H., Sun, P., Fan, T., Yang, X., Zheng, T., & Sun, C. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.12.058 · Cited by 16

Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes

Sogorb‐Esteve, A., Weiner, S., Simrén, J., Swift, I. J., Bocchetta, M., Todd, E. G., Cash, D. M., Bouzigues, A., Russell, L. L., Foster, P. H., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adm9654 · Cited by 19

Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptides

Montoliu‐Gaya, L., Mulder, S. D., Veerhuis, R., & Villegas, S. (2017) · PLoS ONE · doi:10.1371/journal.pone.0188191 · Cited by 16

Astrogliosis, neuritic microstructure, and sex effects: GFAP is an indicator of neuritic orientation in women

Thaker, A. A., McConnell, B. V., Rogers, D., Carlson, N. E., Coughlan, C. M., Jensen, A. M., Lopez‐Paniagua, D., Holden, S. K., Pressman, P., Pelak, V. S., et al. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.06.026 · Cited by 16

Effect of resveratrol and combination of resveratrol and donepezil on the expression of microglial cells and astrocytes in Wistar albino rats of colchicine-induced Alzheimer’s disease

Rao, Y. L., Ganaraja, B., Suresh, P. K., Joy, T., Ullal, S. D., Manjrekar, P., Murlimanju, B. V., & Sharma, B. G. (2023) · 3 Biotech · doi:10.1007/s13205-023-03743-4 · Cited by 14

Digging into the intrinsic capacity concept: Can it be applied to Alzheimer’s disease?

López‐Ortiz, S., Caruso, G., Emanuele, E., Menéndez, H., Peñín‐Grandes, S., Guerrera, C. S., Caraci, F., Nisticò, R., Lucía, A., Santos‐Lozano, A., et al. (2024) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2024.102574 · Cited by 14

Characterization of reduced astrocyte creatine kinase levels in Alzheimer's disease

Zheng, T., Kotol, D., Sjöberg, R., Mitsios, N., Uhlén, M., Zhong, W., Edfors, F., & Mulder, J. (2024) · Glia · doi:10.1002/glia.24569 · Cited by 14

Alteraciones en la corteza motora primaria en la enfermedad de Alzheimer: estudio en el modelo 3xTg-AD

Orta‐Salazar, E., Feria‐Velasco, A., & Díaz-Cintra, S. Y. (2017) · Neurología · doi:10.1016/j.nrl.2017.02.016 · Cited by 18

Designing neuroreparative strategies using aged regenerating animal models

Vanhunsel, S., Beckers, A. M., & Moons, L. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101086 · Cited by 14

Dynamic Changes in Central and Peripheral Neuro-Injury vs. Neuroprotective Serum Markers in COVID-19 Are Modulated by Different Types of Anti-Viral Treatments but Do Not Affect the Incidence of Late and Early Strokes

Laudański, K., Hajj, J., Restrepo, M., Siddiq, K., Okeke, T., & Rader, D. J. (2021) · Biomedicines · doi:10.3390/biomedicines9121791 · Cited by 15

Dysfunction of the neurovascular unit in brain aging

Liu, S., Xu, Y., Chen, F., & Cai, Z. (2023) · Journal of Biomedical Research · doi:10.7555/jbr.36.20220105 · Cited by 14

Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains

Barrera, J., Song, L., Safi, A., Yun, Y., Garrett, M. E., Gamache, J., Premasinghe, I., Sprague, D., Chipman, D., Li, J., et al. (2021) · Molecular Neurodegeneration · doi:10.1186/s13024-021-00481-0 · Cited by 14

Potential of astrocytes in targeting therapy for Alzheimer’s disease

Bi, W., Lei, T., Cai, S., Zhang, X., Yang, Y., Xiao, Z., Wang, L., & Du, H. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109368 · Cited by 13

High intake of chicken and pork proteins aggravates high-fat-diet-induced inflammation and disorder of hippocampal glutamatergic system

Zhang, M., Song, S., Zhao, D., Shi, J., Xu, X., Zhou, G., & Li, C. (2020) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2020.108487 · Cited by 14

Cell-specific copper dyshomeostasis mechanism in Alzheimer’s disease

Okafor, M., Faller, P., & Vitale, N. (2025) · Translational Neurodegeneration · doi:10.1186/s40035-025-00504-6 · Cited by 16

Probing the characteristics and biofunctional effects of disease-affected cells and drug response via machine learning applications

Mudali, D., Jeevanandam, J., & Danquah, M. K. (2020) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2020.1789062 · Cited by 12

The Modulatory Effect of Cyclocarya paliurus Flavonoids on Intestinal Microbiota and Hypothalamus Clock Genes in a Circadian Rhythm Disorder Mouse Model

Sun, Y., Ho, C., Liu, Y., Zhan, S., Wu, Z., Zheng, X., & Zhang, X. (2022) · Nutrients · doi:10.3390/nu14112308 · Cited by 12

Cerebral Organoids Derived from a Parkinson’s Patient Exhibit Unique Pathogenesis from Chikungunya Virus Infection When Compared to a Non-Parkinson’s Patient

Schultz, E. M., Jones, T. J., Xu, S., Dean, D. D., Zechmann, B., & Barr, K. L. (2021) · Pathogens · doi:10.3390/pathogens10070913 · Cited by 12

Intravenous chaperone treatment of late-stage Alzheimer´s disease (AD) mouse model affects amyloid plaque load, reactive gliosis and AD-related genes

Zhang, R., Ohshima, M., Brodin, D., Wang, Y., Morancé, A., Schultzberg, M., Chen, G., & Johansson, J. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03161-x · Cited by 11

Astrocytic proteins involved in regulation of the extracellular environment are increased in the Alzheimer's disease middle temporal gyrus

Liu, H., Tan, A. Y. S., Mehrabi, N. F., Turner, C. P., Curtis, M. A., Faull, R. L. M., Dragunow, M., Singh‐Bains, M. K., & Smith, A. M. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106749 · Cited by 11

NFL and GFAP in (pre)symptomatic RVCL-S carriers: a monogenic cerebral small vessel disease

Wilms, A. E., de Boer, I., Pelzer, N., Veld, S. G. J. G. I. ‘., Middelkoop, H. A. M., Teunissen, C. E., & Terwindt, G. M. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12292-6 · Cited by 10

Astrocytes and their Phenomenal Possibilities in the Treatment of Various Neurodegenerative Disorders: An Overview

Maslova, A. Y., Bazaeva, K. L., Abdullayeva, Z. A., Khazamova, S. O., Zeusheva, K. A., Grechkina, T. A., Semkina, E. N., Abramov, M. A., Mishvelov, A. E., & Povetkin, S. N. (2021) · Journal of Pharmaceutical Research International · doi:10.9734/jpri/2021/v33i33a31772 · Cited by 10

Progressive human-like tauopathy with downstream neurodegeneration and neurovascular compromise in a transgenic rat model

Emmerson, J. T., Carmo, S. D., Liu, Y., Shalhoub, A., Ai, L., Bonomo, Q., Malcolm, J. C., Breuillaud, L., & Cuello, A. C. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106227 · Cited by 11

Primary motor cortex alterations in Alzheimer disease: a study in the 3xTg-AD model

Orta‐Salazar, E., Feria‐Velasco, A., & Díaz-Cintra, S. Y. (2019) · Neurología (English Edition) · doi:10.1016/j.nrleng.2019.02.001 · Cited by 10

Polypathologic Associations with Gray Matter Atrophy in Neurodegenerative Disease

Phillips, J. S., Robinson, J. L., Cousins, K. A. Q., Wolk, D. A., Lee, E. B., McMillan, C. T., Trojanowski, J. Q., Grossman, M., & Irwin, D. J. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0808-23.2023 · Cited by 9

Early resource scarcity causes cortical astrocyte enlargement and sex-specific changes in the orbitofrontal cortex transcriptome in adult rats

Deckers, C., Karbalaei, R., Miles, N. A., Harder, E. V., Witt, E., Harris, E. P., Reissner, K. J., Wimmer, M. E., & Bangasser, D. A. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100607 · Cited by 10

Astrocyte atrophy induced by L-PGDS/PGD2/Src signaling dysfunction in the central amygdala mediates postpartum depression

Sheng, Z., Liu, Q., Song, Y., Ye, B., Li, Y., Song, Y., Liu, J., Zhang, B., Guo, F., Xu, Z., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.083 · Cited by 10

Vagus nerve stimulation (VNS) preventing postoperative cognitive dysfunction (POCD): two potential mechanisms in cognitive function

Xie, Z.-F., Wang, S., Gao, Y., Zhang, Y.-D., Han, Y., Huang, J., Gao, M.-N., & Wang, C.-G. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05091-0 · Cited by 9

A novel cyclic peptide (Naturido) modulates glia–neuron interactions in vitro and reverses ageing-related deficits in senescence-accelerated mice

Ishiguro, S., Shinada, T., Wu, Z., Karimazawa, M., UCHIDATE, M., Nishimura, E., Yasuno, Y., Ebata, M., Sillapakong, P., Ishiguro, H., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245235 · Cited by 9

Targeting glial fibrillary acidic protein in glaucoma: a monoclonal antibody approach to modulate glial reactivity and neuroinflammation for neuroprotection

Guan, C., Zhang, L., Fomo, K. N., Yang, J., Pfeiffer, N., & Grus, F. H. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03482-8 · Cited by 12

Plasma biomarkers predict amyloid pathology in cognitively normal monozygotic twins after 10 years

den Braber, A., Verberk, I. M. W., Tomassen, J., den Dulk, B., Stoops, E., Dage, J. L., Collij, L. E., Barkhof, F., Willemsen, G. A. H. M., Nivard, M. G., et al. (2022) · Brain Communications · doi:10.1093/braincomms/fcad024 · Cited by 8

NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain

Fadul, M. M., Garwood, C. J., Waller, R., Garrett, N., Heath, P. R., Matthews, F. E., Brayne, C., Wharton, S. B., & Simpson, J. E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21010340 · Cited by 9

In vivo and ex vivo gene therapy for neurodegenerative diseases: a promise for disease modification

Ebrahimi, P., Davoudi, E., Sadeghian, R., Zadeh, A. Z., Razmi, E., Heidari, R., Morowvat, M. H., & Sadeghian, I. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03141-4 · Cited by 7

Microglia polarization in heat-induced early neural injury

Wang, L., Zhao, J., Zhu, B., Shen, J.-H., Ye, Z., Peng, Q., & Zhang, Y. (2021) · Archives of Medical Science · doi:10.5114/aoms/116550 · Cited by 7

Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study

Beckers, E., Egroo, M. V., Ashton, N. J., Blennow, K., Vandewalle, G., Zetterberg, H., Poser, B. A., & Jacobs, H. I. L. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae261 · Cited by 9

Impaired glymphatic function is associated with synaptic loss in cognitive impairment

He, K., Wang, J., Wu, J., Chen, X., Chen, H., Li, J., Guo, Q., Huang, Y. H., Guan, Y., Zhao, J., et al. (2026) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-025-07716-y · Cited by 6

Entorhinal cortex astrocytic atrophy in human frontotemporal dementia

Rodriguez, J. J., Zallo, F., Gardenal, E., Cabot, J., & Busquets, X. (2024) · Brain Structure and Function · doi:10.1007/s00429-024-02763-x · Cited by 7

Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD mice

Kour, D., Khajuria, P., Sharma, K., Sharma, A., Sharma, A., Ali, S. M., Wazir, P., Ramajayan, P., Sawant, S. D., Nandi, U., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1525364 · Cited by 8

Serum lipidomics study of Ding-Zhi-Xiao-Wan effect on Alzheimer's disease using online liquid extraction surface analysis coupled to direct infusion mass spectrometry

Zhao, N., Sun, Y., Zong, L., Liu, S., Song, F., Liu, S., & Liu, S. (2018) · International Journal of Mass Spectrometry · doi:10.1016/j.ijms.2018.08.010 · Cited by 6

The role of Tau, amyloid-β and neuroinflammation in the association between cognition and white matter hyperintensities in a southeast Asian cohort

Sandhu, G. K., Vipin, A., Leonardo, J., Zailan, F. Z., Tanoto, P., Lee, F. P. H. E., Sim, X. Y., Ghildiyal, S., Leow, Y. J., Liew, S. Y., et al. (2025) · The Journal of Prevention of Alzheimer s Disease · doi:10.1016/j.tjpad.2025.100300 · Cited by 5

Causality-driven candidate identification for reliable DNA methylation biomarker discovery

Tang, X., Guo, R., Mo, Z., Fu, W., & Qian, X. (2025) · Nature Communications · doi:10.1038/s41467-025-56054-y · Cited by 5

Immunosenescence and Alzheimer’s Disease

Fülöp, T., Larbi, A., Khalil, A., Plotka, A., Laurent, B., Ramassamy, C., Bosco, N., Hirokawa, K., Frost, E. H., & Witkowski, J. M. (2021) · Healthy ageing and longevity · doi:10.1007/978-3-030-87532-9_9 · Cited by 4

Hybrid Vision Transformer–CNN Framework for Alzheimer’s Disease Cell Type Classification: A Comparative Study with Vision–Language Models

Hasan, E., Fuad, M. T. H., Sharif, O., & Wagler, A. E. (2026) · Journal of Imaging · doi:10.3390/jimaging12030098 · Cited by 4

Glial Fibrillary Acidic Protein Levels in Post-Stroke Depression: A Prospective Ischemic Stroke Cohort

Shan, W., Zhao, J., Qiu, C., Xu, G., & Feng, J. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s435006 · Cited by 4

Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC ‐derived astrocytes

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