Review: Astrocytes in Alzheimer's disease and other age‐associated dementias: a supporting player with a central role

The Hallmarks of Aging

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982

Astrocyte-endothelial interactions at the blood-brain barrier

Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129

Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders

Zlokovic, B. V. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3114 · Cited by 2,969

Tripartite synapses: glia, the unacknowledged partner

Araque, A., Parpura, V., Sanzgiri, R. P., & Haydon, P. G. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01349-6 · Cited by 2,529

Genomic analysis of reactive astrogliosis

Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., & Barres, B. A. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.6221-11.2012 · Cited by 2,404

Brain energy metabolism: focus on Astrocyte-neuron metabolic cooperation

Bélanger, M., Allaman, I., & Magistretti, P. J. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.016 · Cited by 2,313

Immune attack: the role of inflammation in Alzheimer disease

Heppner, F. L., Ransohoff, R. M., & Becher, B. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3880 · Cited by 2,134

Oxidative Damage Is the Earliest Event in Alzheimer Disease

Nunomura, A., Perry, G., Aliev, G., Hirai, K., Takeda, A., Balraj, E. K., Jones, P. K., Ghanbari, H., Wataya, T., Shimohama, S., et al. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.8.759 · Cited by 1,885

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

Talbot, K., Wang, H.-Y., Kazi, H., Han, L.-Y., Bakshi, K. P., Stucky, A., Fuino, R. L., Kawaguchi, K. R., Samoyedny, A. J., Wilson, R. S., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci59903 · Cited by 1,871

Tripartite synapses: astrocytes process and control synaptic information

Perea, G., Navarrete, M., & Araque, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.05.001 · Cited by 1,820

Astrocyte activation and reactive gliosis

Pekny, M., & Nilsson, M. (2005) · Glia · doi:10.1002/glia.20207 · Cited by 1,611

Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains

Bushong, E. A., Martone, M. E., Jones, Y. Z., & Ellisman, M. H. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00183.2002 · Cited by 1,578

Uniquely Hominid Features of Adult Human Astrocytes

Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4707-08.2009 · Cited by 1,488

Control of Synapse Number by Glia

Ullian, E. M., Sapperstein, S. K., Christopherson, K. S., & Barres, B. A. (2001) · Science · doi:10.1126/science.291.5504.657 · Cited by 1,380

Fine structural localization of glutamine synthetase in astrocytes of rat brain

Norenberg, M. D., & Martinez-Hernandez, A. (1979) · Brain Research · doi:10.1016/0006-8993(79)90071-4 · Cited by 1,349

Neuropathology of older persons without cognitive impairment from two community-based studies

Bennett, D. A., Schneider, J. A., Arvanitakis, Z., Kelly, J. F., Aggarwal, N. T., Shah, R. C., & Wilson, R. S. (2006) · Neurology · doi:10.1212/01.wnl.0000219668.47116.e6 · Cited by 1,336

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Yamanaka, K., Chun, S. J., Boillee, S., Fujimori-Tonou, N., Yamashita, H., Gutmann, D. H., Takahashi, R., Misawa, H., & Cleveland, D. W. (2008) · Nature Neuroscience · doi:10.1038/nn2047 · Cited by 1,140

Glial fibrillary acidic protein: From intermediate filament assembly and gliosis to neurobiomarker

Yang, Z., & Wang, K. K. W. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.04.003 · Cited by 1,050

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

Garcia, A. D. R., Doan, N., Imura, T., Bush, T. G., & Sofroniew, M. V. (2004) · Nature Neuroscience · doi:10.1038/nn1340 · Cited by 1,019

Adult mouse astrocytes degrade amyloid-β in vitro and in situ

Wyss-Coray, T., Loike, J. D., Brionne, T. C., Lu, E., Anankov, R., Yan, F., Silverstein, S. C., & Husemann, J. (2003) · Nature Medicine · doi:10.1038/nm838 · Cited by 909

Age, Neuropathology, and Dementia

Savva, G. M., Wharton, S. B., Ince, P. G., Forster, G., Matthews, F. E., & Brayne, C. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0806142 · Cited by 900

A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines

Rubio-Perez, J. M., & Morillas-Ruiz, J. M. (2012) · The Scientific World JOURNAL · doi:10.1100/2012/756357 · Cited by 864

Astroglial networks: a step further in neuroglial and gliovascular interactions

Giaume, C., Koulakoff, A., Roux, L., Holcman, D., & Rouach, N. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2757 · Cited by 789

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

Haidet-Phillips, A. M., Hester, M. E., Miranda, C. J., Meyer, K., Braun, L., Frakes, A., Song, S., Likhite, S., Murtha, M. J., Foust, K. D., et al. (2011) · Nature Biotechnology · doi:10.1038/nbt.1957 · Cited by 782

Astrocytic complexity distinguishes the human brain

Oberheim, N. A., Wang, X., Goldman, S., & Nedergaard, M. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.08.004 · Cited by 739

Astrocyte–neuron metabolic relationships: for better and for worse

Allaman, I., Bélanger, M., & Magistretti, P. J. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2010.12.001 · Cited by 639

Heterogeneity of astrocytic form and function.

Oberheim, N. A., Goldman, S. A., & Nedergaard, M. (2012) · Methods in Molecular Biology · doi:10.1007/978-1-61779-452-0_3 · Cited by 638

Astrocyte glycogen and brain energy metabolism

Brown, A. M., & Ransom, B. R. (2007) · Glia · doi:10.1002/glia.20557 · Cited by 626

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease

Jones, L., Holmans, P. A., Hamshere, M. L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013950 · Cited by 606

Amyloid beta oligomers induce impairment of neuronal insulin receptors

Zhao, W., De Felice, F. G., Fernandez, S., Chen, H., Lambert, M. P., Quon, M. J., Krafft, G. A., & Klein, W. L. (2008) · The FASEB Journal · doi:10.1096/fj.06-7703com · Cited by 587

Astrocyte Senescence as a Component of Alzheimer’s Disease

Bhat, R., Crowe, E. P., Bitto, A., Moh, M., Katsetos, C. D., Garcia, F. U., Johnson, F. B., Trojanowski, J. Q., Sell, C., & Torres, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045069 · Cited by 586

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides

Koistinaho, M., Lin, S., Wu, X., Esterman, M., Koger, D., Hanson, J., Higgs, R., Liu, F., Malkani, S., Bales, K. R., et al. (2004) · Nature Medicine · doi:10.1038/nm1058 · Cited by 571

Glial cells in (patho)physiology

Parpura, V., Heneka, M. T., Montana, V., Oliet, S. H. R., Schousboe, A., Haydon, P. G., Stout, R. F., Spray, D. C., Reichenbach, A., Pannicke, T., et al. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07664.x · Cited by 561

Aging-related tau astrogliopathy (ARTAG): Harmonized evaluation strategy

Kovacs, G. G., Ferrer, I., Grinberg, L. T., Alafuzoff, I., Attems, J., Budka, H., Cairns, N. J., Crary, J. F., Duyckaerts, C., Ghetti, B., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1509-x · Cited by 532

Local Ca2+ detection and modulation of synaptic release by astrocytes

Di Castro, M. A., Chuquet, J., Liaudet, N., Bhaukaurally, K., Santello, M., Bouvier, D., Tiret, P., & Volterra, A. (2011) · Nature Neuroscience · doi:10.1038/nn.2929 · Cited by 529

Contribution of glial cells to the development of amyloid plaques in Alzheimer’s disease

Nagele, R. G., Węgiel, J., Venkataraman, V., Imaki, H., Wang, K.-C., & Wegiel, J. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.01.007 · Cited by 522

Cholesterol metabolism in neurons and astrocytes

Pfrieger, F. W., & Ungerer, N. (2011) · Progress in Lipid Research · doi:10.1016/j.plipres.2011.06.002 · Cited by 500

Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease

Olabarria, M., Noristani, H. N., Verkhratsky, A., & Rodríguez, J. J. (2010) · Glia · doi:10.1002/glia.20967 · Cited by 499

Invited review: Neuropathology of tauopathies: principles and practice

Kovacs, G. G. (2015) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12208 · Cited by 492

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer’s Disease

Serrano-Pozo, A., Mielke, M. L., Gómez-Isla, T., Betensky, R. A., Growdon, J. H., Frosch, M. P., & Hyman, B. T. (2011) · The American Journal of Pathology · doi:10.1016/j.ajpath.2011.05.047 · Cited by 488

Astrocytes in Alzheimer's Disease

Verkhratsky, A., Olabarria, M., Noristani, H. N., Yeh, C., & Rodriguez, J. J. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.05.017 · Cited by 470

Cooperative Astrocyte and Dendritic Spine Dynamics at Hippocampal Excitatory Synapses

Haber, M., Zhou, L., & Murai, K. K. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1302-06.2006 · Cited by 437

Neuroinflammatory processes in Alzheimer’s disease

Heneka, M. T., O’Banion, M. K., Terwel, D., & Kummer, M. P. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0438-z · Cited by 433

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

Shao, W., Zhang, S., Tang, M., Zhang, X., Zhou, Z., Yin, Y., Zhou, Q., Huang, Y., Liu, Y., Wawrousek, E. F., et al. (2012) · Nature · doi:10.1038/nature11748 · Cited by 418

GFAP mRNA increases with age in rat and human brain

Nichols, N. R., Day, J. R., Laping, N. J., Johnson, S. A., & Finch, C. E. (1993) · Neurobiology of Aging · doi:10.1016/0197-4580(93)90100-p · Cited by 413

Astroglia in dementia and Alzheimer's disease

Rodriguez, J. J., Olabarria, M., Chvátal, A., & Verkhratsky, A. (2008) · Cell Death and Differentiation · doi:10.1038/cdd.2008.172 · Cited by 409

Isolation of glia from Alzheimer’s mice reveals inflammation and dysfunction

Orre, M., Kamphuis, W., Osborn, L. M., Jansen, A. H. P., Kooijman, L., Bossers, K., & Hol, E. M. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.06.004 · Cited by 394

Do glia drive synaptic and cognitive impairment in disease?

Chung, W.-S., Welsh, C. A., Barres, B. A., & Stevens, B. (2015) · Nature Neuroscience · doi:10.1038/nn.4142 · Cited by 385

Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

Munoz, L., & Ammit, A. J. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.11.010 · Cited by 381

Astrocyte phenotype in relation to Alzheimer‐type pathology in the ageing brain

Simpson, J. E., Ince, P. G., Lace, G., Forster, G., Shaw, P. J., Matthews, F., Savva, G., Brayne, C., & Wharton, S. B. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.05.015 · Cited by 381

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture

Garwood, C. J., Pooler, A. M., Atherton, J., Hanger, D. P., & Noble, W. (2011) · Cell Death & Disease · doi:10.1038/cddis.2011.50 · Cited by 379

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

Zhao, J. J., O’Connor, T., & Vassar, R. J. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-150 · Cited by 379

How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes

Blasko, I., Stampfer‐Kountchev, M., Robatscher, P., Veerhuis, R., Eikelenboom, P., & Grubeck‐Loebenstein, B. (2004) · Aging Cell · doi:10.1111/j.1474-9728.2004.00101.x · Cited by 374

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

Meyer, K., Ferraiuolo, L., Miranda, C. J., Likhite, S., McElroy, S., Renusch, S., Ditsworth, D., Lagier-Tourenne, C., Smith, R. A., Ravits, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1314085111 · Cited by 361

Hippocampal Astrocytes In Situ Exhibit Calcium Oscillations That Occur Independent of Neuronal Activity

Nett, W., Oloff, S., & McCarthy, K. D. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00268.2001 · Cited by 347

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype: Astrocyte senescence in aging brain

Salminen, A., Ojala, J., Kaarniranta, K., Haapasalo, A., Hiltunen, M., & Soininen, H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07738.x · Cited by 333

Much of late life cognitive decline is not due to common neurodegenerative pathologies

Boyle, P. A., Wilson, R. S., Yu, L., Barr, A. M., Honer, W. G., Schneider, J. A., & Bennett, D. A. (2013) · Annals of Neurology · doi:10.1002/ana.23964 · Cited by 323

GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease

Kamphuis, W., Mamber, C., Moeton, M., Kooijman, L., Sluijs, J. A., Jansen, A. H. P., Verveer, M., de Groot, L. R., Smith, V. D., Rangarajan, S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042823 · Cited by 320

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

Furman, J. L., Sama, D. M., Gant, J. C., Beckett, T. L., Murphy, M. P., Bachstetter, A. D., Van Eldik, L. J., & Norris, C. M. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.2323-12.2012 · Cited by 313

Changing perspectives regarding late-life dementia

Fotuhi, M., Hachinski, V., & Whitehouse, P. J. (2009) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.175 · Cited by 291

Genetic insights in Alzheimer's disease

Bettens, K., Sleegers, K., & Van Broeckhoven, C. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70259-4 · Cited by 290

Possible Implications of Insulin Resistance and Glucose Metabolism in Alzheimer's Disease Pathogenesis

Bosco, D., Fava, A., Plastino, M., Montalcini, T., & Pujia, A. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01318.x · Cited by 283

Evidence for a wide extra-astrocytic distribution of S100B in human brain

Steiner, J. H., Bernstein, H., Bielau, H., Berndt, A., Brisch, R., Mawrin, C., Keilhoff, G., & Bogerts, B. (2007) · BMC Neuroscience · doi:10.1186/1471-2202-8-2 · Cited by 282

Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice

Orre, M., Kamphuis, W., Osborn, L. M., Melief, J., Kooijman, L., Huitinga, I., Klooster, J., Bossers, K., & Hol, E. M. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.07.008 · Cited by 279

Epidemiological Pathology of Dementia: Attributable-Risks at Death in the Medical Research Council Cognitive Function and Ageing Study

Matthews, F. E., Brayne, C., Lowe, J., McKeith, I., Wharton, S. B., & Ince, P. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000180 · Cited by 279

Overexpression of Low-Density Lipoprotein Receptor in the Brain Markedly Inhibits Amyloid Deposition and Increases Extracellular Aβ Clearance

Kim, J., Castellano, J. M., Jiang, H., Basak, J. M., Parsadanian, M., Pham, V., Mason, S. M., Paul, S. M., & Holtzman, D. M. (2009) · Neuron · doi:10.1016/j.neuron.2009.11.013 · Cited by 274

Direct Astrocytic Contacts Regulate Local Maturation of Dendritic Spines

西田, 秀., & Okabe, S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4466-06.2007 · Cited by 268

Molecular comparison of GLT1 + and ALDH1L1 + astrocytes in vivo in astroglial reporter mice

Yang, Y., Vidensky, S., Jin, L., Jie, C., Lorenzini, I., Frankl, M., & Rothstein, J. D. (2010) · Glia · doi:10.1002/glia.21089 · Cited by 264

Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain

Butterfield, D. A., & Debra Boyd-kimball, A. (2004) · Brain Pathology · doi:10.1111/j.1750-3639.2004.tb00087.x · Cited by 263

Cooperation between independent hippocampal synapses is controlled by glutamate uptake

Arnth-Jensen, N., Jabaudon, D., & Scanziani, M. (2002) · Nature Neuroscience · doi:10.1038/nn825 · Cited by 256

Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease

Kamphuis, W., Middeldorp, J., Kooijman, L., Sluijs, J. A., Kooi, E., Moeton, M., Freriks, M., Mizee, M. R., & Hol, E. M. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.09.035 · Cited by 251

Alexander Disease

Messing, A., Brenner, M., Feany, M. B., Nedergaard, M., & Goldman, J. E. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.5384-11.2012 · Cited by 250

Glial Cells and Neurotransmission

Auld, D. S., & Robitaille, R. (2003) · Neuron · doi:10.1016/s0896-6273(03)00607-x · Cited by 239

Elevated Oxidative Stress and Decreased Antioxidant Function in the Human Hippocampus and Frontal Cortex with Increasing Age: Implications for Neurodegeneration in Alzheimer’s Disease

Venkateshappa, C., Harish, G., Mahadevan, A., Srinivas Bharath, M. M., & Shankar, S. K. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0755-8 · Cited by 232

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

Merlini, M., Meyer, E. P., Ulmann-Schuler, A., & Nitsch, R. M. (2011) · Acta Neuropathologica · doi:10.1007/s00401-011-0834-y · Cited by 225

Functions of Mature Mammalian Astrocytes: A Current View

Kimelberg, H. K. (2010) · The Neuroscientist · doi:10.1177/1073858409342593 · Cited by 218

White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses

Simpson, J. E., Fernando, M. S., Clark, L., Ince, P. G., Matthews, F., Forster, G., O'Brien, J. T., Barber, R., Kalaria, R. N., Brayne, C., et al. (2007) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2007.00828.x · Cited by 215

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice

Wang, L., Gutmann, D. H., & Roos, R. P. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq463 · Cited by 214

Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer’s disease patients

Tomimoto, H., Akiguchi, I., Suenaga, T., Nishimura, M., Wakita, H., Nakamura, S., & Kimura, J. (1996) · Stroke · doi:10.1161/01.str.27.11.2069 · Cited by 204

Glia as drivers of abnormal neuronal activity

Robel, S., & Sontheimer, H. W. (2015) · Nature Neuroscience · doi:10.1038/nn.4184 · Cited by 198

Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer’s pathology and APOE genotype

Simpson, J. E., Ince, P. G., Shaw, P. J., Heath, P. R., Raman, R., Garwood, C. J., Gelsthorpe, C., Baxter, L., Forster, G., Matthews, F. E., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.04.013 · Cited by 197

P53- and CD95-associated apoptosis in neurodegenerative diseases.

de la Monte, S. M., Sohn, Y. K., Ganju, N., & Wands, J. R. (1998) · PubMed · Cited by 195

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

Basak, J. M., Verghese, P. B., Yoon, H., Kim, J., & Holtzman, D. M. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.288746 · Cited by 192

The contribution of astrocytes to the regulation of cerebral blood flow

Howarth, C. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00103 · Cited by 187

Astrocytic involvement in learning and memory consolidation

Gibbs, M. E., Hutchinson, D. S., & Hertz, L. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.02.001 · Cited by 179

Spatial and temporal expression of S100B in cells of oligodendrocyte lineage

Hachem, S., Aguirre, A. A., Vives, V., Marks, A., Gallo, V., & Legraverend, C. (2005) · Glia · doi:10.1002/glia.20184 · Cited by 169

Glial influences on BBB functions and molecular players in immune cell trafficking

Lécuyer, M., Kébir, H., & Prat, A. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.10.004 · Cited by 166

Visualization of S100B‐positive neurons and glia in the central nervous system of EGFP transgenic mice

Vives, V., Alonso, G., Cohen-Solal, A., Joubert, D., & Legraverend, C. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10552 · Cited by 161

Insulin Promotes Glycogen Storage and Cell Proliferation in Primary Human Astrocytes

Heni, M., Hennige, A. M., Peter, A., Siegel-Axel, D. I., Ordelheide, A., Krebs, N., Machicao, F. E., Fritsche, A., Häring, H., & Staiger, H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021594 · Cited by 158

Human brain S100β and S100β mRNA expression increases with age: Pathogenic implications for Alzheimer's disease

Sheng, J. G., Mrak, R. E., Rovnaghi, C. R., Kozłowska, E., Eldik, L. J. V., & Griffin, W. S. T. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00037-1 · Cited by 156

Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

Ince, P. G., Highley, J. R., Kirby, J., Wharton, S. B., Takahashi, H., Strong, M. J., & Shaw, P. J. (2011) · Acta Neuropathologica · doi:10.1007/s00401-011-0913-0 · Cited by 154

Role of the neuropathology of Alzheimer disease in dementia in the oldest-old

Haroutunian, V., Schnaider-Beeri, M., Schmeidler, J., Wysocki, M., Purohit, D. P., Perl, D. P., Libow, L. S., Lesser, G. T., Maroukian, M., & Grossman, H. T. (2008) · Archives of Neurology · doi:10.1001/archneur.65.9.1211 · Cited by 154

Astrocytes containing amyloid beta-protein (Abeta)-positive granules are associated with Abeta40-positive diffuse plaques in the aged human brain.

(1998) · Europe PMC (PubMed Central) · Cited by 146

The role of astrocytes in amyloid β-protein toxicity and clearance

Thal, D. R. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.04.021 · Cited by 146

Decreased amyloid-β and increased neuronal hyperactivity by immunotherapy in Alzheimer's models

Busche, M. A., Grienberger, C., Keskin, A. D., Song, B., Neumann, U., Staufenbiel, M., Förstl, H., & Konnerth, A. (2015) · Nature Neuroscience · doi:10.1038/nn.4163 · Cited by 146

Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis

Lambert, J.-C., Grenier-Boley, B., Chouraki, V., Heath, S., Zelenika, D., Fievet, N., Hannequin, D., Pasquier, F., Hanon, O., Brice, A., et al. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100018 · Cited by 144

Homeostatic function of astrocytes: Ca2+ and Na+ signalling

Parpura, V., & Verkhratsky, A. (2012) · Translational Neuroscience · doi:10.2478/s13380-012-0040-y · Cited by 142

Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission

Schousboe, A., Sarup, A., Bak, L. K., Waagepetersen, H. S., & Larsson, O. M. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.11.001 · Cited by 142

Glial Neurobiology

Verkhratsky, A., & Butt, A. M. (2007) · Wiley eBooks · doi:10.1002/9780470517796 · Cited by 142

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer’s disease

Kimbrough, I. F., Robel, S., Roberson, E. D., & Sontheimer, H. W. (2015) · Brain · doi:10.1093/brain/awv327 · Cited by 140

Amyloid β-protein (Aβ)-containing astrocytes are located preferentially near N-terminal-truncated Aβ deposits in the human entorhinal cortex

Thal, D. R., Schultz, C., Dehghani, F., Yamaguchi, H., Braak, H., & Braak, E. (2000) · Acta Neuropathologica · doi:10.1007/s004010000242 · Cited by 136

The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked by Prominent RNA Oxidation in Vulnerable Neurons

Nunomura, A., Tamaoki, T., Motohashi, N., Nakamura, M., McKeel, D. W., Tabaton, M., Lee, H., Smith, M. A., Perry, G. L., & Zhu, X. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318248e614 · Cited by 134

Alzheimer’s disease variants with the genome-wide significance are significantly enriched in immune pathways and active in immune cells

Jiang, Q., Jin, S., Jiang, Y., Liao, M., Feng, R., Zhang, L., Liu, G., & Hao, J. (2017) · Molecular Neurobiology · doi:10.1007/s12035-015-9670-8 · Cited by 132

Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease

Prohovnik, I., Perl, D. P., Davis, K. L., Libow, L. S., Lesser, G. T., & Haroutunian, V. H. (2006) · Neurology · doi:10.1212/01.wnl.0000191298.68045.50 · Cited by 131

Specification of CNS glia from neural stem cells in the embryonic neuroepithelium

Kessaris, N., Pringle, N. P., & Richardson, W. D. (2007) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2006.2013 · Cited by 130

Epidemiological Neuropathology: The MRC Cognitive Function and Aging Study Experience

Wharton, S. B., Brayne, C., Savva, G. M., Matthews, F. E., Forster, G., Simpson, J. E., Lace, G., & Ince, P. G. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-091402 · Cited by 129

Focal astrocyte loss is followed by microvascular damage, with subsequent repair of the blood‐brain barrier in the apparent absence of direct astrocytic contact

Willis, C. L., Nolan, C. C., Reith, S. N., Lister, T., Prior, M. J. W., Guérin, C. J., Mavroudis, G., & Ray, D. E. (2003) · Glia · doi:10.1002/glia.10333 · Cited by 128

Increased transcription of the astrocyte gene GFAP during middle-age is attenuated by food restriction: Implications for the role of oxidative stress

Morgan, T. E., Rozovsky, I., Goldsmith, S. K., Stone, D. J., Yoshida, T., & Finch, C. E. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00120-2 · Cited by 126

Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain

Lovell, M. A., Soman, S., & Bradley, M. A. (2011) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2011.08.003 · Cited by 124

Reversible disruption of tight junction complexes in the rat blood‐brain barrier, following transitory focal astrocyte loss

Willis, C. L., Leach, L., Clarke, G., Nolan, C. C., & Ray, D. E. (2004) · Glia · doi:10.1002/glia.20049 · Cited by 123

Mild to moderate Alzheimer dementia with insufficient neuropathological changes

Serrano‐Pozo, A., Qian, J., Monsell, S. E., Blacker, D., Gómez‐Isla, T., Betensky, R. A., Growdon, J. H., Johnson, K. A., Frosch, M. P., Sperling, R. A., et al. (2014) · Annals of Neurology · doi:10.1002/ana.24125 · Cited by 120

Astrocytes and neuroinflammation in Alzheimer's disease

Phillips, E. C., Croft, C. L., Crane, K., O’Neill, M. J., Hutton, M. L., Hanger, D. P., Garwood, C. J., & Noble, W. J. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140155 · Cited by 115

Age related changes of various markers of astrocytes in senescence-accelerated mice hippocampus

Wu, Y., Zhang, A., & Yew, D. T. W. (2005) · Neurochemistry International · doi:10.1016/j.neuint.2005.01.002 · Cited by 111

Apoptosis of astrocytes with enhanced lysosomal activity and oligodendrocytes in white matter lesions in Alzheimer's disease

Kobayashi, K., Hayashi, M., Nakano, H., Fukutani, Y., Sasaki, K., Shimazaki, M., & Koshino, Y. (2002) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2002.00390.x · Cited by 110

Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks

Jing, R., Wilhelmsson, U., Goodwill, W., Li, L., Pan, Y., Pekny, M., & Skalli, O. (2007) · Journal of Cell Science · doi:10.1242/jcs.03423 · Cited by 110

Reevaluating Metabolism in Alzheimer's Disease from the Perspective of the Astrocyte-Neuron Lactate Shuttle Model

Newington, J. T., Harris, R. A., & Cumming, R. C. (2013) · Journal of Neurodegenerative Diseases · doi:10.1155/2013/234572 · Cited by 109

Morphological diversities of CD44 positive astrocytes in the cerebral cortex of normal subjects and patients with Alzheimer's disease

Akiyama, H., Tooyama, I., Kawamata, T., Ikeda, K., & McGeer, P. L. (1993) · Brain Research · doi:10.1016/0006-8993(93)91160-t · Cited by 107

Astrocytic degeneration relates to the severity of disease in frontotemporal dementia

Broe, M. (2004) · Brain · doi:10.1093/brain/awh250 · Cited by 106

Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain

Simpson, J. E., Ince, P. G., Haynes, L. J., Theaker, R., Gelsthorpe, C., Baxter, L., Forster, G., Lace, G., Shaw, P. J., Matthews, F. E., et al. (2009) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2009.01030.x · Cited by 104

A New Splice Variant of Glial Fibrillary Acidic Protein, GFAPε, Interacts with the Presenilin Proteins

Nielsen, A. L., Holm, I. E., Johansen, M., Bonven, B. J., Jørgensen, P., & Jørgensen, A. L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m112121200 · Cited by 103

Developmental Origins of Astrocyte Heterogeneity: The final frontier of CNS development

Chaboub, L. S., & Deneen, B. (2012) · Developmental Neuroscience · doi:10.1159/000343723 · Cited by 103

Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors

Garwood, C. J., Ratcliffe, L. E., Morgan, S. V., Simpson, J. E., Owens, H., Vazquez-Villaseñor, I., Heath, P. R., Romero, I. A., Ince, P. G., & Wharton, S. B. (2015) · Molecular Brain · doi:10.1186/s13041-015-0138-6 · Cited by 101

High prevalence of thorn-shaped astrocytes in the aged human medial temporal lobe

Schultz, C., Ghebremedhin, E., Tredici, K. D., Rüb, U., & Braak, H. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(03)00113-1 · Cited by 92

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology

Fernandez, A. M., Jiménez, S., Mecha, M., Dávila, D., Guaza, C., Vitórica, J., & Torres‐Alemán, I. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.128 · Cited by 86

Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion

Martinac, J. A., Craft, D. K., Su, J. H., Kim, R. C., & Cotman, C. W. (2001) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00231-1 · Cited by 84

NDRG2 as a marker protein for brain astrocytes

Flügge, G., Araya-Callís, C., Garea‐Rodríguez, E., Stadelmann, C., & Fuchs, E. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1837-5 · Cited by 82

Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation

Vijayan, V. K., Gedes, J. W., Anderson, K. J., Chang-Chui, H., Ellis, W. G., & Cotman, C. W. (1991) · Experimental Neurology · doi:10.1016/0014-4886(91)90115-s · Cited by 74

Glial involvement in diffuse Lewy body disease

Terada, S., Ishizu, H., Yokota, O., Tsuchiya, K., Nakashima, H., Ishihara, T., Fujita, D., Uéda, K., Ikeda, K., & Kuroda, S. (2003) · Acta Neuropathologica · doi:10.1007/s00401-002-0622-9 · Cited by 73

Glial levels determine severity of white matter disease in Alzheimer's disease: a neuropathological study of glial changes

Sjöbeck, M., & Englund, E. M. (2003) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2003.00456.x · Cited by 73

Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury

Genís, L., Dávila, D., Fernández, S., Pozo-Rodrigálvarez, A., Martínez‐Murillo, R., & Torres‐Alemán, I. (2014) · F1000Research · doi:10.12688/f1000research.3-28.v2 · Cited by 73

Astrogliosis and the ApoE Genotype

Overmyer, M., Helisalmi, S., Soininen, H. S., Laakso, M., Riekkinen, P., & Alafuzoff, I. I. (1999) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000017128 · Cited by 68

The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain

Fluteau, A., Ince, P. G., Minett, T., Matthews, F. E., Brayne, C., Garwood, C. J., Ratcliffe, L. E., Morgan, S., Heath, P. R., Shaw, P. J., et al. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.10.001 · Cited by 66

Astrocytes: Glutamate transport and alternate splicing of transporters

Lee, A., & Pow, D. V. (2010) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2010.09.016 · Cited by 61

Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study

on behalf of the MRC Cognitive Function and Ageing Neuropathology Study Group, Wharton, S. B., Minett, T., Drew, D., Forster, G., Matthews, F. E., Brayne, C., & Ince, P. G. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-016-0275-x · Cited by 61

Correlation between astrocyte apoptosis and Alzheimer changes in gray matter lesions in Alzheimer's disease

Kobayashi, K., Hayashi, M., Nakano, H., Shimazaki, M., Sugimori, K., & Koshino, Y. (2005) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6606 · Cited by 58

Mesial Temporal Astrocyte Tau Pathology in the MRC-CFAS Ageing Brain Cohort

Lace, G., Ince, P. G., Brayne, C., Savva, G. M., Matthews, F. E., de Silva, R., Simpson, J. E., & Wharton, S. B. (2012) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000341581 · Cited by 52

A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment

Mathur, R., Ince, P. G., Minett, T., Garwood, C. J., Shaw, P. J., Matthews, F. E., Brayne, C., Simpson, J. E., Wharton, S. B., & on behalf of the MRC Cognitive Function and Ageing Neuropathology Study Group (2015) · PLOS ONE · doi:10.1371/journal.pone.0118463 · Cited by 52

Selective Astrocytic Endothelin-1 Overexpression Contributes to Dementia Associated with Ischemic Stroke by Exaggerating Astrocyte-Derived Amyloid Secretion

Hung, V., Yeung, P. K. K., Lai, A. K. W., Ho, M. C., Lo, A., Chan, K. C., Wu, E. X., Chung, S. S., Cheung, C. W., & Chung, S. K. (2015) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2015.109 · Cited by 51

A new role for astrocytes: β-amyloid homeostasis and degradation

Nicoll, J. A. R., & Weller, R. O. (2003) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(03)00109-6 · Cited by 51

Calcium dysregulation in relation to Alzheimer‐type pathology in the ageing brain

Garwood, C., Faizullabhoy, A., Wharton, S. B., Ince, P. G., Heath, P. R., Shaw, P. J., Baxter, L., Gelsthorpe, C., Forster, G., Matthews, F. E., et al. (2013) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12033 · Cited by 47

DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to A lzheimer's neuropathology progression: a population‐based study in the M edical R esearch C ouncil C ognitive F unction and A geing S tudy ( MRC ‐ CFAS ) cohort

Garwood, C. J., Simpson, J. E., Mashhadi, S. A., Axe, C., Wilson, S., Heath, P. R., Shaw, P. J., Matthews, F. E., Brayne, C., Ince, P. G., et al. (2014) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12156 · Cited by 42

Lower Counts of Astroglia and Activated Microglia in Patients with Alzheimer's Disease with Regular Use of Non-Steroidal Anti-Inflammatory Drugs

Alafuzoff, I., Overmyer, M., Helisalmi, S., & Soininen, H. (2000) · Journal of Alzheimer's Disease · doi:10.3233/jad-2000-2105 · Cited by 42

Neurobiology of Vascular Dementia

Enciu, A., Constantinescu, S. N., Popescu, L. M., Muresanu, D. F., & Popescu, B. O. (2011) · Journal of Aging Research · doi:10.4061/2011/401604 · Cited by 34

Isolation of enriched glial populations from post-mortem human CNS material by immuno-laser capture microdissection

Waller, R., Woodroofe, M. N., Francese, S., Heath, P. R., Wharton, S. B., Ince, P. G., Sharrack, B., & Simpson, J. E. (2012) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2012.04.014 · Cited by 31

Functional impact of glycogen degradation on astrocytic signalling

Müller, M. S. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140157 · Cited by 25

N-myc downstream-regulated gene 2 in the nervous system: from expression pattern to function

Lin, K. L., Yin, A., Yao, L., & Li, Y. (2015) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmv082 · Cited by 23

Astrocytes reassessment - an evolving concept part one: embryology, biology, morphology and reactivity

Şovrea, A. S., & Boşca, A. B. (2013) · Journal of Molecular Psychiatry · doi:10.1186/2049-9256-1-18 · Cited by 22

Tau-negative astrocytic star-like inclusions and coiled bodies in dementia with Lewy bodies

Terada, S., Ishizu, H., Haraguchi, T., Takehisa, Y., Tanabe, Y., Kawai, K., & Kuroda, S. (2000) · Acta Neuropathologica · doi:10.1007/s004010000213 · Cited by 21

Imaging Exocytosis and Recycling of Synaptic-Like Microvesicles in AstrocytesPreprint

Bezzi, P., & Volterra, A. (2014) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot081711 · Cited by 12

The Epidemiological Neuropathology of Dementia and the Implications for Drug Development

Stephan, B. C. M., Wharton, S. B., Simpson, J. E., Matthews, F. E., Ince, P. G., & Brayne, C. (2012) · Neurodegenerative Disease Management · doi:10.2217/nmt.12.51 · Cited by 7

From Molecule to Clinic and Community for Neurodegeneration: Research to Bridge Translational Gaps

Brayne, C., Barker, R. A., Harold, D. H., Ince, P. G., Savva, G. M., Williams, J. H., Williams‐Gray, C. H., & Wharton, S. B. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-129006 · Cited by 5

Blood-based biomarkers for Alzheimer's disease: towards clinical implementation

Teunissen, C. E., Verberk, I. M. W., Thijssen, E. H., Vermunt, L., Hansson, O., Zetterberg, H., van der Flier, W. M., Mielke, M. M., & del Campo, M. (2022) · The Lancet Neurology · doi:10.1016/s1474-4422(21)00361-6 · Cited by 1,045

The Amyloid Cascade Hypothesis in Alzheimer’s Disease: It’s Time to Change Our Mind

Ricciarelli, R., & Fedele, E. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666170116143743 · Cited by 380

Blood‐based biomarkers for Alzheimer's disease

Leuzy, A., Mattsson, N., Palmqvist, S., Janelidze, S., Dage, J. L., & Hansson, O. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202114408 · Cited by 372

Glial Fibrillary Acidic Protein in Serum is Increased in Alzheimer’s Disease and Correlates with Cognitive Impairment

Oeckl, P., Halbgebauer, S., Anderl-Straub, S., Steinacker, P., Huss, A. M., Neugebauer, H., von Arnim, C. A. F., Diehl-Schmid, J., Grimmer, T., Kornhuber, J., et al. (2019) · Journal of Alzheimer’s Disease · doi:10.3233/jad-180325 · Cited by 345

Astrocytes: Role and Functions in Brain Pathologies

Siracusa, R., Fusco, R., & Cuzzocrea, S. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01114 · Cited by 361

Astroglia in dementia and Alzheimer's disease

Rodriguez, J. J., Olabarria, M., Chvátal, A., & Verkhratsky, A. (2008) · Cell Death and Differentiation · doi:10.1038/cdd.2008.172 · Cited by 409

Astrocytes in Alzheimer's disease

Nevmerzhytska, N., & Skibo, G. (2025) · Ageing & Longevity · doi:10.47855/jal9020-2025-4-2

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Iram, T., & Frenkel, D. (2012) · Current Signal Transduction Therapy · doi:10.2174/157436212799278232 · Cited by 7

Contribution of astrocytes to neuropathology of neurodegenerative diseases

Acıoğlu, Ç., Li, L., & Elkabes, S. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147291 · Cited by 119

The neglected co-star in the dementia drama: the putative roles of astrocytes in the pathogeneses of major neurocognitive disorders

Jo, W. K., Law, A. C. K., & Chung, S. K. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.171 · Cited by 40