Methamphetamine use in the United States: Epidemiological update and implications for prevention, treatment, and harm reduction

Jones, Christopher M.; Houry, Debra; Han, Beth; Baldwin, Grant; Vivolo‐Kantor, Alana; Compton, Wilson M.

doi:10.1111/nyas.14688

Cited by 202Opioid Use Disorder TreatmentSubstance Abuse Treatment and OutcomesHIV, Drug Use, Sexual Risk

Methamphetamine use in the United States: Epidemiological update and implications for prevention, treatment, and harm reduction

Open access

Jones, Christopher M., Houry, Debra, Han, Beth, Baldwin, Grant, Vivolo‐Kantor, Alana, Compton, Wilson M.·2022·Annals of the New York Academy of Sciences

DOI 10.1111/nyas.14688PMC PMC9097961

Open this paper in CoChat — free account

Abstract

Recent attention has focused on the growing role of psychostimulants, such as methamphetamine in overdose deaths. Methamphetamine is an addictive and potent stimulant, and its use is associated with a range of physical and mental health harms, overdose, and mortality. Adding to the complexity of this resurgent methamphetamine threat is the reality that the increases in methamphetamine availability and harms are occurring in the midst of and intertwined with the ongoing opioid overdose crisis. Opioid involvement in psychostimulant‐involved overdose deaths increased from 34.5% of overdose deaths in 2010 to 53.5% in 2019—an increase of more than 50%. This latest evolution of the nation's overdose epidemic poses novel challenges for prevention, treatment, and harm reduction. This narrative review synthesizes what is known about changing patterns of methamphetamine use with and without opioids in the United States, other characteristics associated with methamphetamine use, the contributions of the changing illicit drug supply to use patterns and overdose risk, motivations for couse of methamphetamine and opioids, and awareness of exposure to opioids via the illicit methamphetamine supply. Finally, the review summarizes illustrative community and health system strategies and research opportunities to advance prevention, treatment, and harm reduction policies, programs, and practices.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/nyas.14688

Cites

100 of 100 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Methamphetamine use is another growing global public health concern.
“Likewise, methamphetamine use is another growing global public health concern.(Jones et al., 2022; Paulus & Stewart, 2020)”
From A systematic review and meta-analysis of psychosocial interventions for persons with comorbid anxiety and substance use disorders (2024) · cites this paper as Jones et al., 2022

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Monitoring the Future national survey results on drug use, 1975-2017: Volume I, secondary school students
Miech, R., Johnston, L. A., O'Malley, P., Bachman, J., Schulenberg, J., & Patrick, M. E. (2005) · doi:10.3998/2027.42/146530 · Cited by 1,771 · see citing works
Drug Overdose Deaths in the United States, 1999–2020
Hedegaard, H., Miniño, A., Spencer, M. R., & Warner, M. (2021) · doi:10.15620/cdc:112340 · Cited by 1,283 · see citing works
Trends and Geographic Patterns in Drug and Synthetic Opioid Overdose Deaths — United States, 2013–2019
Mattson, C. L., Tanz, L. J., Quinn, K., Kariisa, M., Patel, P., & Davis, N. L. (2021) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm7006a4 · Cited by 1,068 · see citing works
Peer-Delivered Recovery Support Services for Addictions in the United States: A Systematic Review
Bassuk, E. L., Hanson, J., Greene, R. N., Richard, M. K., & Laudet, A. B. (2016) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2016.01.003 · Cited by 559 · see citing works
Social determinants and the health of drug users: socioeconomic status, homelessness, and incarceration.
(2002) · PubMed Central · Cited by 522 · see citing works
Assessing the effectiveness of drug courts on recidivism: A meta-analytic review of traditional and non-traditional drug courts
Mitchell, O., Wilson, D. B., Eggers, A., et al. (2011) · Journal of Criminal Justice · doi:10.1016/j.jcrimjus.2011.11.009 · Cited by 450 · see citing works
The need for speed: an update on methamphetamine addiction
Barr, A. M., Panenka, W. J., MacEwan, G. W., Thornton, A. E., Lang, D. J., Honer, W. G., & Lecomte, T. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0635 · Cited by 442 · see citing works
Methamphetamine Use, Methamphetamine Use Disorder, and Associated Overdose Deaths Among US Adults
Han, B., Compton, W. M., Jones, C. M., Einstein, E. B., & Volkow, N. D. (2021) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2021.2588 · Cited by 380 · see citing works
Self-citation
Dropout Rates of In-Person Psychosocial Substance Use Disorder Treatments: A Systematic Review and Meta-Analysis
Lappan, S. N., Brown, A. W., & Hendricks, P. S. (2020) · Addiction · doi:10.1111/add.14793 · Cited by 370 · see citing works
Twin epidemics: The surging rise of methamphetamine use in chronic opioid users
Ellis, M. S., Kasper, Z. A., & Cicero, T. J. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.08.029 · Cited by 356 · see citing works
Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis
Ashok, A. H., Mizuno, Y., Volkow, N. D., & Howes, O. D. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.0135 · Cited by 330 · see citing works
Neurobiology, Clinical Presentation, and Treatment of Methamphetamine Use Disorder: A Review
Paulus, M. P., & Stewart, J. L. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.0246 · Cited by 310 · see citing works
Benefits of peer support groups in the treatment of addiction
Tracy, K., & Wallace, S. (2016) · Substance Abuse and Rehabilitation · doi:10.2147/sar.s81535 · Cited by 308 · see citing works
Polysubstance Use: A Broader Understanding of Substance Use During the Opioid Crisis
Cicero, T. J., Ellis, M. S., & Kasper, Z. A. (2019) · American Journal of Public Health · doi:10.2105/ajph.2019.305412 · Cited by 286 · see citing works
Comparative efficacy and acceptability of psychosocial interventions for individuals with cocaine and amphetamine addiction: A systematic review and network meta-analysis
Crescenzo, F. D., Ciabattini, M., D’Alò, G. L., Giorgi, R. D., Giovane, C. D., Cassar, C., Janiri, L., Clark, N. C., Ostacher, M. J., & Cipriani, A. (2018) · PLoS Medicine · doi:10.1371/journal.pmed.1002715 · Cited by 283 · see citing works
What is chemsex and why does it matter?
McCall, H., Adams, N., Mason, D., et al. (2015) · BMJ · doi:10.1136/bmj.h5790 · Cited by 265 · see citing works
Prescription Opioid Misuse and Use of Alcohol and Other Substances Among High School Students — Youth Risk Behavior Survey, United States, 2019
Jones, C. M., Clayton, H. B., Deputy, N. P., Roehler, D. R., Ko, J. Y., Esser, M. B., Brookmeyer, K. A., & Hertz, M. F. (2020) · MMWR Supplements · doi:10.15585/mmwr.su6901a5 · Cited by 253 · see citing works
Self-citation
A systematic review of rural-specific barriers to medication treatment for opioid use disorder in the United States
Lister, J. J., Weaver, A., Ellis, J. D., Himle, J. A., & Ledgerwood, D. M. (2019) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2019.1694536 · Cited by 253 · see citing works
Patterns and Characteristics of Methamphetamine Use Among Adults — United States, 2015–2018
Jones, C. M., Compton, W. M., & Mustaquim, D. (2020) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6912a1 · Cited by 246 · see citing works
Self-citation
Vital Signs: Characteristics of Drug Overdose Deaths Involving Opioids and Stimulants — 24 States and the District of Columbia, January–June 2019
O’Donnell, J. K., Gladden, R. M., Mattson, C. L., Hunter, C. T., & Davis, N. L. (2020) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6935a1 · Cited by 246 · see citing works
Sexualised drug use in the United Kingdom (UK): A review of the literature
Edmundson, C., Heinsbroek, E., Glass, R., Hope, V. D., Mohammed, H. P., White, M., & Desai, M. (2018) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2018.02.002 · Cited by 242 · see citing works
Epidemiology of HIV Among Injecting and Non-injecting Drug Users: Current Trends and Implications for Interventions
Strathdee, S. A., & Stockman, J. K. (2010) · Current HIV/AIDS Reports · doi:10.1007/s11904-010-0043-7 · Cited by 241 · see citing works
Treatment of stimulant use disorder: A systematic review of reviews
Ronsley, C., Nolan, S., Knight, R., Hayashi, K., Klimas, J., Walley, A., Wood, E., & Fairbairn, N. (2020) · PLOS ONE · doi:10.1371/journal.pone.0234809 · Cited by 222 · see citing works
Methamphetamine: Effects on the brain, gut and immune system
Prakash, M. D., Tangalakis, K., Antonipillai, J., Stojanovska, L., Nurgali, K., & Apostolopoulos, V. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.009 · Cited by 220 · see citing works
Substance-Use Outcomes at 18 Months Past Baseline
Spoth, R. L., Redmond, C. R., Shin, C., Greenberg, M. T., Clair, S., & Feinberg, M. E. (2007) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2007.01.014 · Cited by 203 · see citing works
Heroin and Methamphetamine Injection: An Emerging Drug Use Pattern
Al-Tayyib, A., Koester, S., Langegger, S., & Raville, L. (2017) · Substance Use & Misuse · doi:10.1080/10826084.2016.1271432 · Cited by 203 · see citing works
Contingency management for the treatment of methamphetamine use disorder: A systematic review
Brown, H. D., & DeFulio, A. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108307 · Cited by 171 · see citing works
Sex, drugs and smart phone applications: findings from semistructured interviews with men who have sex with men diagnosed with <i>Shigella flexneri</i> 3a in England and Wales: Table 1
Gilbart, V. L., Simms, I., Jenkins, C., Furegato, M., Gobin, M., Oliver, I., Hart, G., Gill, O. N., & Hughes, G. (2015) · Sexually Transmitted Infections · doi:10.1136/sextrans-2015-052014 · Cited by 170 · see citing works
Crystalline methamphetamine use and methamphetamine‐related harms in Australia
Degenhardt, L., Sara, G., McKetin, R., Roxburgh, A., Dobbins, T., Farrell, M., Burns, L., & Hall, W. D. (2017) · Drug and Alcohol Review · doi:10.1111/dar.12426 · Cited by 159 · see citing works
Seattle’s Law Enforcement Assisted Diversion (LEAD): Program effects on recidivism outcomes
Collins, S. E., Lonczak, H. S., & Clifasefi, S. L. (2017) · Evaluation and Program Planning · doi:10.1016/j.evalprogplan.2017.05.008 · Cited by 151 · see citing works
The rise in non‐fatal and fatal overdoses involving stimulants with and without opioids in the United States
Hoots, B., Vivolo-Kantor, A. M., & Seth, P. (2020) · Addiction · doi:10.1111/add.14878 · Cited by 150 · see citing works
Self-citation
Innovation During COVID-19: Improving Addiction Treatment Access
Samuels, E. A., Clark, S. A., Wunsch, C., Keeler, L. A. J., Reddy, N. G., Vanjani, R., & Wightman, R. (2020) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000685 · Cited by 143 · see citing works
Increases in methamphetamine use among heroin treatment admissions in the United States, 2008–17
Jones, C. M., Underwood, N., & Compton, W. M. (2020) · Addiction · doi:10.1111/add.14812 · Cited by 142 · see citing works
Self-citation
Methamphetamine Overdose Deaths in the US by Sex and Race and Ethnicity
Han, B., Cotto, J., Etz, K., Einstein, E. B., Compton, W. M., & Volkow, N. D. (2021) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.4321 · Cited by 140 · see citing works
Self-citation
Why the FUSS (Fentanyl Urine Screen Study)? A cross-sectional survey to characterize an emerging threat to people who use drugs in British Columbia, Canada
Amlani, A., McKee, G., Khamis, N., Raghukumar, G., Tsang, E., & Buxton, J. A. (2015) · Harm Reduction Journal · doi:10.1186/s12954-015-0088-4 · Cited by 134 · see citing works
A nationally representative analysis of “twin epidemics”: Rising rates of methamphetamine use among persons who use opioids
Strickland, J. C., Havens, J. R., & Stoops, W. W. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107592 · Cited by 133 · see citing works
Fentanyl and fentanyl analogs in the illicit stimulant supply: results from U.S. drug seizure data, 2011-2016.
Park, J. N., Rashidi, E., Foti, K., Zoorob, M., Sherman, S., & Alexander, G. C. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108416 · Cited by 128 · see citing works
Rates, characteristics and circumstances of methamphetamine‐related death in Australia: a national 7‐year study
Darke, S. G., Kaye, S. S., & Duflou, J. A. (2017) · Addiction · doi:10.1111/add.13897 · Cited by 125 · see citing works
Substance use patterns and health profiles among US adults who use opioids, methamphetamine, or both, 2015-2018
Shearer, R. D., Howell, B. A., Bart, G. B., & Winkelman, T. N. A. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108162 · Cited by 124 · see citing works
Transcranial magnetic stimulation, deep brain stimulation, and other forms of neuromodulation for substance use disorders: Review of modalities and implications for treatment
Mahoney, J. J., Hanlon, C. A., Marshalek, P. J., Rezai, A. R., & Krinke, L. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117149 · Cited by 121 · see citing works
Resurgent Methamphetamine Use at Treatment Admission in the United States, 2008–2017
Jones, C. M., Olsen, E. O., O’Donnell, J. K., & Mustaquim, D. (2020) · American Journal of Public Health · doi:10.2105/ajph.2019.305527 · Cited by 115 · see citing works
Self-citation
Long-term Effects of Universal Preventive Interventions on Methamphetamine Use Among Adolescents
Spoth, R. L., Clair, S., Shin, C., & Redmond, C. R. (2006) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.160.9.876 · Cited by 112 · see citing works
Nationwide dissemination of contingency management: The veterans administration initiative
Petry, N. M., DePhilippis, D., Rash, C. J., Drapkin, M. L., & McKay, J. R. (2014) · American Journal on Addictions · doi:10.1111/j.1521-0391.2014.12092.x · Cited by 110 · see citing works
Criminal justice continuum for opioid users at risk of overdose
Brinkley‐Rubinstein, L., Zaller, N. D., Martino, S., Cloud, D. H., McCauley, E., Heise, A., & Seal, D. W. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.02.024 · Cited by 109 · see citing works
Long-term efficacy of contingency management treatment based on objective indicators of abstinence from illicit substance use up to 1 year following treatment: A meta-analysis.
Ginley, M. K., Pfund, R. A., Rash, C. J., & Zajac, K. (2021) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000552 · Cited by 108 · see citing works
Drug Overdose Deaths in the United States, 1999-2019.
Hedegaard, H. B., Miniño, A., & Warner, M. (2020) · PubMed · Cited by 101 · see citing works
A scoping review of post opioid-overdose interventions
Bagley, S. M., Schoenberger, S. F., Waye, K. M., & Walley, A. Y. (2019) · Preventive Medicine · doi:10.1016/j.ypmed.2019.105813 · Cited by 101 · see citing works
Prevalence and nature of cardiovascular disease in methamphetamine-related death: A national study
Darke, S. G., Duflou, J. A., & Kaye, S. S. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.07.001 · Cited by 100 · see citing works
Association between methamphetamine use and retention among patients with opioid use disorders treated with buprenorphine
Tsui, J. I., Mayfield, J., Speaker, E. C., Yakup, S., Ries, R. K., Funai, H., Leroux, B. G., & Merrill, J. O. (2019) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2019.10.005 · Cited by 100 · see citing works
Increasing methamphetamine injection among non-MSM who inject drugs in King County, Washington
Glick, S. N., Burt, R. D., Kummer, K., Tinsley, J., Banta‐Green, C. J., & Golden, M. R. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.10.011 · Cited by 99 · see citing works
Targeting Youth to Prevent Later Substance Use Disorder: An Underutilized Response to the US Opioid Crisis
Compton, W. M., Jones, C. M., Baldwin, G. T., Harding, F. M., Blanco, C., & Wargo, E. M. (2019) · American Journal of Public Health · doi:10.2105/ajph.2019.305020 · Cited by 98 · see citing works
Self-citation
Telehealth for Substance-Using Populations in the Age of Coronavirus Disease 2019
Lin, L. A., Fernandez, A. C., & Bonar, E. E. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.1698 · Cited by 97 · see citing works
Reasons for Stimulant Use Among Latino Gay Men in San Francisco: A Comparison Between Methamphetamine and Cocaine Users
Díaz, R. M. (2005) · Journal of Urban Health · doi:10.1093/jurban/jti026 · Cited by 95 · see citing works
Contingency management treatments: controversies and challenges
Petry, N. M. (2010) · Addiction · doi:10.1111/j.1360-0443.2009.02879.x · Cited by 94 · see citing works
Syringe services programs: An examination of legal, policy, and funding barriers in the midst of the evolving opioid crisis in the U.S.
Jones, C. M. (2019) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2019.04.006 · Cited by 94 · see citing works
Self-citation
Theories of Addiction: Methamphetamine Users' Explanations for Continuing Drug Use and Relapse
Newton, T. F., Garza, R. D. L., Kalechstein, A. D., Tziortzis, D., & Jacobsen, C. A. (2009) · American Journal on Addictions · doi:10.1080/10550490902925920 · Cited by 93 · see citing works
Post opioid overdose outreach by public health and public safety agencies: Exploration of emerging programs in Massachusetts
Formica, S. W., Apsler, R., Wilkins, L. E., Ruiz, S., Reilly, B., & Walley, A. Y. (2018) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2018.01.001 · Cited by 93 · see citing works
The national implementation of Contingency Management (CM) in the Department of Veterans Affairs: Attendance at CM sessions and substance use outcomes
DePhilippis, D., Petry, N. M., Bonn‐Miller, M. O., Rosenbach, S. B., & McKay, J. R. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.12.020 · Cited by 91 · see citing works
Unintentional drug overdose: Is more frequent use of non-prescribed buprenorphine associated with lower risk of overdose?
Carlson, R. G., Daniulaityte, R., Silverstein, S. M., Nahhas, R. W., & Martins, S. S. (2020) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2020.102722 · Cited by 90 · see citing works
Pharmacological treatments for methamphetamine addiction: current status and future directions
Ballester, J., Valentine, G. W., & Sofuoglu, M. (2016) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2017.1268916 · Cited by 89 · see citing works
PROSPER delivery of universal preventive interventions with young adolescents: long-term effects on emerging adult substance misuse and associated risk behaviors
Spoth, R. L., Redmond, C. R., Shin, C., Greenberg, M. T., Feinberg, M. E., & Trudeau, L. (2017) · Psychological Medicine · doi:10.1017/s0033291717000691 · Cited by 82 · see citing works
Increasing Heroin‐Methamphetamine (Goofball) Use and Related Morbidity Among Seattle Area People Who Inject Drugs
Glick, S. N., Klein, K. S., Tinsley, J., & Golden, M. R. (2020) · American Journal on Addictions · doi:10.1111/ajad.13115 · Cited by 81 · see citing works
Substance Use among Men Who Have Sex with Men
Compton, W. M., & Jones, C. M. (2021) · New England Journal of Medicine · doi:10.1056/nejmra2033007 · Cited by 80 · see citing works
Self-citation
Co-use of methamphetamine and opioids among people in treatment in Oregon: A qualitative examination of interrelated structural, community, and individual-level factors
Lopez, A. M., Dhatt, Z. K., Howe, M., Al-Nassir, M., Billing, A. S., Artigiani, E., & Wish, E. D. (2021) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2020.103098 · Cited by 79 · see citing works
A Systematic Review of the Symptom Profile and Course of Methamphetamine-Associated Psychosis
Voce, A., Calabria, B., Burns, R. A., Castle, D. J., & McKetin, R. (2019) · Substance Use & Misuse · doi:10.1080/10826084.2018.1521430 · Cited by 75 · see citing works
Methamphetamine Use and Its Correlates among Individuals with Opioid Use Disorder in a Midwestern U.S. City
Daniulaityte, R., Silverstein, S. M., Crawford, T. N., Martins, S. S., Zule, W. A., Zaragoza, A. J., & Carlson, R. G. (2020) · Substance Use & Misuse · doi:10.1080/10826084.2020.1765805 · Cited by 71 · see citing works
An evolving problem: Methamphetamine production and trafficking in the United States
Shukla, R. K., Crump, J. L., & Chrisco, E. S. (2012) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2012.07.004 · Cited by 68 · see citing works
Trends in characteristics of individuals who use methamphetamine in the United States, 2015-2018
Palamar, J. J., Han, B. H., & Keyes, K. M. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108089 · Cited by 67 · see citing works
Self-citation
Co-involvement of Opioids in Drug Overdose Deaths Involving Cocaine and Psychostimulants
Hedegaard, H. B. (2021) · doi:10.15620/cdc:103966 · Cited by 65 · see citing works
Known fentanyl use among clients of harm reduction sites in British Columbia, Canada
Karamouzian, M., Papamihali, K., Graham, B. M., Crabtree, A., Mill, C., Kuo, M. E., Young, S., & Buxton, J. A. (2020) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2020.102665 · Cited by 62 · see citing works
A police-led addiction treatment referral program in Gloucester, MA: Implementation and participants' experiences
Schiff, D. M., Drainoni, M., Weinstein, Z., Chan, L., Bair‐Merritt, M. H., & Rosenbloom, D. (2017) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2017.09.003 · Cited by 61 · see citing works
COVID-19-related treatment service disruptions among people with single- and polysubstance use concerns
Mellis, A. M., Potenza, M. N., & Hulsey, J. N. (2020) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2020.108180 · Cited by 61 · see citing works
“Like Yin and Yang”: Perceptions of Methamphetamine Benefits and Consequences Among People Who Use Opioids in Rural Communities
Baker, R., Leichtling, G. J., Hildebran, C., Pinela, C., Waddell, E. N., Sidlow, C., Leahy, J. M., & Korthuis, P. T. (2020) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000669 · Cited by 58 · see citing works
The continued rise of methamphetamine use among people who use heroin in the United States
Strickland, J. C., Stoops, W. W., Dunn, K. E., Smith, K. E., & Havens, J. R. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108750 · Cited by 56 · see citing works
DARK Classics in Chemical Neuroscience: Methamphetamine
Abbruscato, T. J., & Trippier, P. C. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00123 · Cited by 55 · see citing works
Adolescent Opioid Misuse Attributable to Adverse Childhood Experiences
Swedo, E. A., Sumner, S. A., de Fijter, S., Werhan, L., Norris, K., Beauregard, J. L., Montgomery, M. P., Rose, E. B., Hillis, S. D., & Massetti, G. M. (2020) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2020.05.001 · Cited by 55 · see citing works
Trends in Methamphetamine Use Among Men Who Have Sex with Men in New York City, 2004–2017
Rivera, A. V., Harriman, G., Carrillo, S. A., & Braunstein, S. (2020) · AIDS and Behavior · doi:10.1007/s10461-020-03097-5 · Cited by 55 · see citing works
A New Survey of Methamphetamine Users in Treatment: Who They are, Why They Like “Meth,” and Why They Need Additional Services
Maxwell, J. C. (2013) · Substance Use & Misuse · doi:10.3109/10826084.2013.841244 · Cited by 51 · see citing works
Outreach to people who survive opioid overdose: Linkage and retention in treatment
Langabeer, J. R., Champagne‐Langabeer, T., Luber, S., et al. (2019) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2019.12.008 · Cited by 51 · see citing works
Service Involvement Across Multiple Sectors Among People Who Use Opioids, Methamphetamine, or Both, United States—2015–2018
Howell, B. A., Bart, G. B., Wang, E. A., & Winkelman, T. N. A. (2020) · Medical Care · doi:10.1097/mlr.0000000000001460 · Cited by 48 · see citing works
Development of a Statewide, Publicly Accessible Drug Overdose Surveillance and Information System
Marshall, B. D. L., Yedinak, J. L., Goyer, J., et al. (2017) · American Journal of Public Health · doi:10.2105/ajph.2017.304007 · Cited by 43 · see citing works
Recent trends and associated factors of amphetamine-type stimulant overdoses in emergency departments
Vivolo-Kantor, A. M., Hoots, B., Seth, P., & Jones, C. M. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108323 · Cited by 43 · see citing works
Self-citation
Shifts in drug seizures in the United States during the COVID-19 pandemic
Palamar, J. J., Le, A., Carr, T. H., et al. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108580 · Cited by 42 · see citing works
Pattern and related factors of cognitive impairment among chronic methamphetamine users
Wang, T., Fan, T., Bao, Y., Li, X.-D., Liang, C., Wang, R., Ma, J., Han, Y., Meng, S., Wu, P., et al. (2017) · American Journal on Addictions · doi:10.1111/ajad.12505 · Cited by 39 · see citing works
National Drug Threat Assessment 2006
(2006) · PsycEXTRA Dataset · doi:10.1037/e568962006-001 · Cited by 39 · see citing works
Developing interagency collaboration to address the opioid epidemic: A scoping review of joint criminal justice and healthcare initiatives
Yatsco, A. J., Champagne‐Langabeer, T., Holder, T. F., Stotts, A. L., & Langabeer, J. R. (2020) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2020.102849 · Cited by 39 · see citing works
Mental Health and Substance Use Disorder Comorbidity among Methamphetamine-Using Men Who have Sex with Men
Fletcher, J. B., Swendeman, D. T., & Reback, C. J. (2018) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2018.1447173 · Cited by 38 · see citing works
“It’s Crazy What Meth Can Help You Do”: Lay Beliefs, Practices, and Experiences of Using Methamphetamine to Self-Treat Symptoms of Opioid Withdrawal
Silverstein, S. M., Daniulaityte, R., Getz, K., & Zule, W. A. (2021) · Substance Use & Misuse · doi:10.1080/10826084.2021.1949612 · Cited by 38 · see citing works
To Battle The Opioid Overdose Epidemic, Deploy The ‘Cascade Of Care’ Model
Williams, A. R., Nunes, E. V., & Olfson, M. (2017) · doi:10.7916/d8rx9qf3 · Cited by 37 · see citing works
Methamphetamine injecting is associated with phylogenetic clustering of hepatitis C virus infection among street-involved youth in Vancouver, Canada
Cunningham, E. B., Jacka, B. P., DeBeck, K., Applegate, T. L., Harrigan, P. R., Krajden, M., Marshall, B. D. L., Montaner, J. S. G., Lima, V. D., Olmstead, A. D., et al. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.04.005 · Cited by 35 · see citing works
Increased Drug Use and STI Risk with Injection Drug Use Among HIV-Seronegative Heterosexual Methamphetamine Users
Cheng, W. S., Garfein, R. S., Semple, S. J., Strathdee, S. A., Zians, J. K., & Patterson, T. L. (2010) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2010.10399781 · Cited by 32 · see citing works
Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use
Stevens, M. W., Stevens, M. W., Stevens, M. W., Stevens, M. W., Tawney, R., Tawney, R., Tawney, R., Tawney, R. L., West, C. M., West, C. M., et al. (2013) · mAbs · doi:10.4161/mabs.27620 · Cited by 32 · see citing works
Methamphetamine exposures reported to United States poison control centers, 2000–2019
Chen, T., Spiller, H. A., Badeti, J., Funk, A. R., Zhu, M., & Smith, G. A. (2021) · Clinical Toxicology · doi:10.1080/15563650.2020.1861287 · Cited by 29 · see citing works
Immunotherapy for treating methamphetamine, heroin and cocaine use disorders
Xiaoshan, T., Junjie, Y., Wenqing, W., Zeng, Y., Jiaping, L., Shanshan, L., Nandakumar, K. S., & Kui, C. (2019) · Drug Discovery Today · doi:10.1016/j.drudis.2019.07.009 · Cited by 28 · see citing works
Lessons from Scott County — Progress or Paralysis on Harm Reduction?
Kishore, S., Hayden, M. C., & Rich, J. D. (2019) · New England Journal of Medicine · doi:10.1056/nejmp1901276 · Cited by 26 · see citing works
Vaccine development against methamphetamine drug addiction
Hossain, M. K., Hassanzadeganroudsari, M., Nurgali, K., & Apostolopoulos, V. (2020) · Expert Review of Vaccines · doi:10.1080/14760584.2020.1857738 · Cited by 23 · see citing works
Interest in reducing methamphetamine and opioid use among syringe services program participants in Washington State
McMahan, V., Kingston, S., Newman, A., Stekler, J. D., Glick, S. N., & Banta‐Green, C. J. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108243 · Cited by 18 · see citing works
Local Overdose Fatality Review Team Recommendations for Overdose Death Prevention
Haas, E. E., Truong, C., Bartolomei-Hill, L., Baier, M., Bazron, B., & Rebbert‐Franklin, K. (2018) · Health Promotion Practice · doi:10.1177/1524839918797617 · Cited by 17 · see citing works
A Public Health Guide to Ending the Opioid Epidemic
(2019) · Oxford University Press eBooks · doi:10.1093/oso/9780190056810.001.0001 · Cited by 10 · see citing works
Human Garbage and Physical Garbage: A Sociological Case Example of Institutional Violence
Ben‐Yehuda, N., & Einstein, S. (1984) · International Journal of the Addictions · doi:10.3109/10826088409055814 · Cited by 7 · see citing works

Flagged first, then by citations

Research works printed but not linked: 7

[17]Han B, Cotto J, Etz K, 2021. Methamphetamine overdose deaths in the U.S. by sex and race and ethnicity. JAMA Psychiatry 7895: 564– 567. PMC8100861 33471025
[23]Canadian Centre on Substance Use and Addiction. 2019. Canadian Community Epidemiology Network on Drug Use Bulletin: changes in stimulant use and related harms: focus on methamphetamine and cocaine. Accessed April 16, 2021. https://www.ccsa.ca/sites/default/files/2019-05/CCSA-CCENDU-Stimulant-Use-Related-Harms-Bulletin-2019-en.pdf.
[31]Center for Behavioral Health Statistics and Quality. 2020. Results from the 2019 National Survey on Drug Use and Health: Detailed Tables. Rockville, MD: Substance Abuse and Mental Health Services Administration. 39437027
[75]Bureau of Justice Assistance. Overdose fatality review data system guidance version 1.0. 2020. Accessed May 7, 2021. https://www.cossapresources.org/Content/Documents/Articles/OFR_Data_System_Guidance_Oct_2020.pdf.
[108]McMahan WM, Kingston S, Newman A, Stekler JD, 2020. Interest in reducing methamphetamine and opioid use among syringe services program participants in Washington State. Drug Alcohol Depend. 216: 108243. 32911134 PMC9632690
[125]Jones CM, Compton WM & Mustaquim D. 2020. Patterns and characteristics of methamphetamine use among adults – United States, 2015–2018. Morb. Mortal. Wkly. Rep 69: 317– 323. PMC7725509 32214077
[126]Jones CM, Olsen EO, O’Donnell J, 2020. Resurgent methamphetamine use at treatment admission in the United States, 2008–2017. Am. J. Public Health 110: 509– 516. 32078347 PMC7067087

Sorted by citations

A qualitative study on perceptions and experiences of overdose among people who smoke drugs in Vancouver, British Columbia
Ivsins, A., Bonn, M., McNeil, R., Boyd, J., & Kerr, T. (2024) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2024.111275 · Cited by 22 · see citing works
Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder
Brett, J., Knock, E., Korthuis, P. T., Liknaitzky, P., Murnane, K. S., Nicholas, C. R., Patterson, J. C., & Stauffer, C. S. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1123424 · Cited by 16 · see citing works
A systematic review and meta-analysis of psychosocial interventions for persons with comorbid anxiety and substance use disorders
Nardi, W. R., Kelly, P., Roy, A., Becker, S., Brewer, J., & Sun, S. (2024) · Journal of Substance Use and Addiction Treatment · doi:10.1016/j.josat.2024.209442 · Cited by 11 · see citing works

Analysis of Methamphetamine and its Metabolites in Urine from a Habitual User of the Stimulant.
MORITA, M., & ANDO, H. (1983) · Eisei kagaku · doi:10.1248/jhs1956.29.5_318 · Cited by 5 · see citing works
Exploring brain morphology in poly-stimulant abuse: shape, volume, and surface area abnormalities in Ecstasy-cocaine- and methamphetamine-preferring individuals
Payer, D. E., Park, M. T. M., Kish, S. J., et al. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.09.546 · Cited by 2 · see citing works
Behavioral effects of four novel synthetic cathinone analogs in rodents
Gatch, M. B., Shetty, R. A., Sumien, N., et al. (2020) · Addiction Biology · doi:10.1111/adb.12987 · Cited by 29 · see citing works
A qualitative study: harm reduction and opioid overdose strategies for Black and Latinx opioid overdose survivors
Serrano, M. D. (2022) · Journal of Social Work Practice in the Addictions · doi:10.1080/1533256x.2022.2149970 · Cited by 1 · see citing works
Understanding Polarizing Community Perspectives on Harm Reduction Strategies
Creasy, S. L., Thompson, J. R., Mair, C., & Burke, J. G. (2021) · PubMed Central · doi:10.13023/jah.0304.07 · Cited by 4 · see citing works

Authors: Jones, C. M., Houry, D., Han, B., Baldwin, G., Vivolo‐Kantor, A., & Compton, W. M.
Affiliations: Centers for Disease Control and Prevention (US)
National Institutes of Health (US)
Division of Overdose Prevention, National Center for Injury Prevention and Control Centers for Disease Control and Prevention Atlanta Georgia
Corresponding author: Jones, Christopher M.
ORCID: Jones, Christopher M.
Houry, Debra
Han, Beth
Baldwin, Grant
Compton, Wilson M.
Venue: Annals of the New York Academy of Sciences
Publisher: Wiley
Published: 2021-09-24
Volume: 1508
Issue: 1
Pages: 3-22
ISSN: 0077-8923 (ISSN-L)
1749-6632
DOI: 10.1111/nyas.14688
PMC: PMC9097961
OpenAlex: W3199254314
Cited by: 202
References: 100
Citations by year: 2026: 45 · 2025: 48 · 2024: 57 · 2023: 33 · 2022: 18
FWCI: 4.81
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Annals of the New York Academy of Sciences (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (CC999999)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Keywords: methamphetamine, psychostimulants, opioid overdose, polydrug use, illicit drug supply, drug use patterns, harm reduction, substance use prevention, addiction treatment, causes of drug use, United States
MeSH terms: Opioid Epidemic, Humans, Methamphetamine, Illicit Drugs, United States, Harm Reduction, Drug Overdose

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Methamphetamine use in the United States: Epidemiological update and implications for prevention, treatment, and harm reduction

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks