Lifestyle intervention can reduce the risk of gestational diabetes: a meta‐analysis of randomized controlled trials
Abstract
Summary: This study aimed to examine the effect of lifestyle intervention on the risk of gestational diabetes mellitus (GDM). We searched PubMed, Springer and other databases to retrieve articles published in English and Chinese up to 30 September 2015. The inclusion criteria were randomized controlled trials evaluating the effects of lifestyle intervention on risk of GDM. Exclusion criteria were studies with prepregnancy diabetes mellitus or interventions with nutrient supplements. Random‐effect and fixed‐effect model analyses were used to obtain pooled relative risks and 95% confidence intervals (CIs) of diet and physical activity on the risk of GDM. Subgroup analyses were performed to check the consistency of effect sizes across groups where appropriate. We identified 29 randomized controlled trials with 11,487 pregnant women, addressing the effect of lifestyle intervention on the risk of GDM. In the pooled analysis, either diet or physical activity resulted in an 18% (95%CI 5–30%) reduction in the risk of GDM (P = 0.0091). Subgroup analysis showed that such intervention was effective among women with intervention before the 15th gestational week (relative risk: 0.80, 95%CI 0.66–0.97), but not among women receiving the intervention afterwards. We conclude that lifestyle modification during pregnancy, especially before the 15th gestational week, can reduce the risk of GDM. © 2016 World Obesity
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Interventions provided during early weeks of gestation showed promising results.
“Interestingly, interventions provided during early weeks of gestation showed promising results [22].”
From Effectiveness of pre-pregnancy lifestyle in preventing gestational diabetes mellitus—a systematic review and meta-analysis of 257,876 pregnancies (2023) · cites this paper as [22]
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“Interestingly, interventions provided during early weeks of gestation showed promising results [22].”
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- Authors
- Song, C., Li, J., Leng, J., Ma, R. C., & Yang, X.
- Affiliations
- Tianjin Economic-Technological Development Area (CN)
- Tianjin Medical University (CN)
- Tianjin Women's and Children's Health Center (CN)
- Chinese University of Hong Kong (HK)
- Corresponding author
- Yang, X.
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2016-07-15
- Volume
- 17
- Issue
- 10
- Pages
- 960-969
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W2483234986
- Cited by
- 227
- References
- 13
- Citations by year
- 2026: 14 · 2025: 23 · 2024: 26 · 2023: 31 · 2022: 23 · 2021: 32 · 2020: 33 · 2019: 11 · 2018: 18 · 2017: 12 · 2016: 2
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obesity Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Universidad de Granada
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- gestational diabetes mellitus, lifestyle intervention, dietary intervention, physical activity, pregnancy, diabetes prevention, intervention timing, pregnant women
- MeSH terms
- Diet, Female, Health Education, Humans, Obesity, Patient Compliance, Pregnancy, Prenatal Care, Primary Prevention, Exercise, Randomized Controlled Trials as Topic, Diabetes, Gestational, Risk Reduction Behavior
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