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Cited by 127Sexual function and dysfunction studiesPelvic floor disorders treatmentsGenital Health and Disease

Vulvodynia - an evidence-based literature review and proposed treatment algorithm

De Andres, Jose, Sanchis‐Lopez, Nerea, Asensio‐Samper, Juan Marcos, Fabregat‐Cid, Gustavo, Villanueva‐Perez, Vicente L., Monsalve Dolz, Vicente, Minguez, Ana·2016·Pain Practice
DOI 10.1111/papr.12274
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Abstract

OBJECTIVE: We searched the medical literature from the last 15 years (1998 to 2013) relating to the etiology, diagnosis, and treatment of vulvodynia. The evidence was reviewed supporting the therapeutic proposals currently in use and propose the incorporation of novel, minimally invasive, interventional therapies, within the context of a multidisciplinary approach. METHODS: This was a systematic review of all relevant studies with no language restrictions. Studies were identified through Medline/PubMed (1998 to March 2013), the Cochrane Library (2001 to 2013), and conference records and book chapters. The keywords used included "chronic pelvic pain," "vulvodynia," "vestibulodynia," and search terms "etiology," "diagnosis," and "treatment" were added. The levels of evidence were assessed using grading system for "Therapy/Prevention/Etiology/Harm" developed by the Centre for Evidence-Based Medicine (CEBM). The grading system assists in clinical decision-making, and we decided to use "The Grading of Recommendations Assessment, Development, and Evaluation (GRADE)." RESULTS: A total of 391 papers were assessed. Of these, 215 were analyzed and 175 were excluded, as they pertained to areas not directly related to the disease under review. CONCLUSION: The optimal therapy for vulvar pain syndrome remains elusive, with low percentages of therapeutic success, using either local or systemic pharmacological approaches. Surgery involving invasive and often irreversible therapeutic procedures has resulted in success for certain subtypes of vulvodynia. We present a multidisciplinary approach whereby pain treatment units may provide an intermediate level of care between standard medical and surgical treatments.

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  • A multidisciplinary approach is recommended for vulvodynia, and pelvic floor physiotherapy and CBT are considered first-line treatment.

    “Regarding treatment, a multidisciplinary approach is recommended, and pelvic floor physiotherapy and cognitive behavioural therapy (CBT) are considered first line treatment (Bergeron et al., 2020; De Andres et al., 2016; Rosen and Dawson, 2019; Sadownik, 2014, van der Meijden et al., 2017).”

    From Internet-based treatment for vulvodynia (EMBLA) – Study protocol for a randomised controlled study (2021) · cites this paper as De Andres et al., 2016

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Authors
De Andres, J., Sanchis‐Lopez, N., Asensio‐Samper, J. M., Fabregat‐Cid, G., Villanueva‐Perez, V. L., Monsalve Dolz, V., & Minguez, A.
Affiliations
  • Valencia University Medical School Valencia Spain
  • Hospital General Universitario De Valencia (ES)
  • Department of Anesthesiology Critical Care and Pain Management General University Hospital Valencia Spain
Venue
Pain Practice
Publisher
Wiley
Published
2015-01-12
Volume
16
Issue
2
Pages
204-236
ISSN
  • 1530-7085 (ISSN-L)
  • 1533-2500
DOI
10.1111/papr.12274
OpenAlex
W1994079615
Cited by
127
References
218
Citations by year
2026: 4 · 2025: 7 · 2024: 5 · 2023: 7 · 2022: 43 · 2021: 12 · 2020: 11 · 2019: 11 · 2018: 8 · 2017: 12 · 2016: 4 · 2015: 3
FWCI
1.24
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Pain Practice (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
  • Health Sciences › Medicine › Surgery › Genital Health and Disease
Keywords
vulvodynia, vestibulodynia, chronic pelvic pain, etiology, diagnosis, treatment algorithm, pharmacotherapy, surgical treatment, minimally invasive therapy, multidisciplinary pain management
MeSH terms
Algorithms, Female, Humans, Evidence-Based Medicine, Vulvodynia

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