Clinical validity and intrarater and test–retest reliability of the Structured Clinical Interview for DSM‐5 – Clinician Version (SCID‐5‐CV)
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AIM: The Structured Clinical Interview for the DSM is one of the most used diagnostic instruments in clinical research worldwide. The current Clinician Version of the instrument (SCID-5-CV) has not yet been assessed in respect to its psychometric qualities. We aimed to assess the clinical validity and different reliability indicators (interrater test-retest, joint interview, face-to-face vs telephone application) of the SCID-5-CV in a large sample of 180 non-prototypical and psychiatric patients based on interviews conducted by raters with different levels of clinical experience. METHODS: The SCID-5-CV was administered face-to-face and by telephone by 12 psychiatrists/psychologists who took turns as raters and observers. Clinical diagnoses were established according to DSM-5 criteria and the longitudinal, expert, all data (LEAD) procedure. We calculated the percentage of agreement, diagnostic sensitivity and specificity, and the level of agreement (kappa) for diagnostic categories and specific diagnoses. RESULTS: The percentage of positive agreement between the interview and clinical diagnoses ranged between 73% and 97% and the diagnostic sensitivity/specificity were >0.70. In the joint interview, the levels of positive agreement were high (>75%) and kappa levels were >0.70 for most diagnoses. The values were less expressive, but still adequate, for interrater test-retest interviews. CONCLUSION: The SCID-5-CV presented excellent reliability and high specificity as assessed with different methods. The clinical validity of the instrument was also confirmed, which supports its use in daily clinical practice. We highlight the adequacy of the instrument to be used via telephone and the need for careful use by professionals with little experience in psychiatric clinical practice.
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The SCID-5 has good inter-rater reliability, with high positive agreement on the presence of a diagnosis.
“The SCID-5 has good inter-rater reliability, with high positive agreement on the presence of a diagnosis (Osório et al., 2019)”
From I've Seen Enough: Measuring the Toll of Content Moderation on Mental Health (2025) · cites this paper as Osório et al., 2019
The Reliability section reports high positive agreement in joint interviews for all diagnoses except schizophreniform disorder. It describes interrater test–retest reliability as adequate, but says positive agreement was lower for several mood and anxiety diagnoses. The claim omits these qualifications. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThe SCID-5-CV can reliably be used for screening purposes in both in-patient and out-patient settings.
“Therefore, it was concluded that the interview can reliably be used for screening purposes in both in-patient and out-patient settings.”
From A Single-Session Process-Based Cognitive-Behavioral Intervention Combined with Multimodal Rehabilitation Treatment for Chronic Pain Associated with Emotional Disorders (2024) · cites this paper as [72]
The Participants section includes both psychiatric inpatients and outpatients, and the Discussion reports excellent reliability and clinical validity for diagnostic assessment. It does not specifically establish reliability for screening purposes in each setting; the Discussion also cautions that clinicians with little psychiatric experience may not make correct diagnoses. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThe SCID-5-S has good validity and reliability.
“The results of these studies show that the validity and reliability of the SCID-S was good.”
From The effectiveness and cost-effectiveness of attachment-based family therapy for young adults with high suicidal ideation: protocol of a randomized controlled trial (2024) · cites this paper as [35]
The Discussion concludes that the SCID-5-CV has excellent reliability and demonstrated clinical validity. The claim names the SCID-5-S (and the citing sentence says SCID-S), but the paper evaluates the Clinician Version; it does not establish those properties for an instrument with either cited name. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThe SCID-5 has demonstrated excellent reliability, high specificity, and high clinical validity.
“The SCID-5 has demonstrated excellent reliability, high specificity, and high clinical validity (Osório et al., 2019).”
From Feeling more confident to encounter negative emotions: The mediating role of distress tolerance on the relationship between self-efficacy and outcomes of exposure and response prevention for OCD (2024) · cites this paper as Osório et al., 2019
Telephone-conducted SCID-5 interviews show only slightly inferior reliability compared to face-to-face interviews, supporting their use for research purposes.
“While the SCID-5 is intended to be delivered face-to-face, interviews conducted via telephone have been found to show only slightly inferior reliability, supporting their use for research purposes (61).”
From Personalised depression forecasting using mobile sensor data and ecological momentary assessment (2022) · cites this paper as [61]
The SCID-5-CV presents excellent reliability, with Cohen's κ ranging from 0.70 to 0.75.
“The SCID-5-CV presents excellent reliability, with Cohen’s κ ranging from 0.70 to 0.75 (50).”
From Prevalence and 10-year stability of personality disorders from adolescence to young adulthood in a high-risk sample (2022) · cites this paper as [50]
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- Authors
- Osório, F. L., Loureiro, S. R., Hallak, J. E. C., Machado‐de‐Sousa, J. P., Ushirohira, J. M., Baes, C. V. W., Apolinario, T. D., Donadon, M. F., Bolsoni, L. M., Guimarães, T., Fracon, V. S., Silva‐Rodrigues, A. P. C., Pizeta, F. A., Souza, R. M., Sanches, R. F., dos Santos, R. G., Martin‐Santos, R., & Crippa, J. A. S.
- Affiliations
- Medical School of Ribeirão Preto São Paulo University Ribeirão Preto Brazil
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR)
- Clinics Hospital of Ribeirão Preto (BR)
- National Institute For Science and Technology (INCT‐TM, CNPq) Brasília Brazil
- ORCID
- Venue
- Psychiatry and Clinical Neurosciences
- Publisher
- Wiley
- Published
- 2019-10-14
- Volume
- 73
- Issue
- 12
- Pages
- 754-760
- ISSN
- 1323-1316 (ISSN-L)
- 1440-1819
- OpenAlex
- W2971897729
- Cited by
- 348
- References
- 27
- Citations by year
- 2026: 52 · 2025: 54 · 2024: 71 · 2023: 57 · 2022: 53 · 2021: 50 · 2020: 11
- FWCI
- 19.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychiatry and Clinical Neurosciences (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (465458/2014‐9, Process 301321/2016‐7)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2014/50891‐1, Process no. 17/18000‐8)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Reliability and Agreement in Measurement
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- clinical validity, inter-rater reliability, test-retest reliability, telephone administration, sensitivity and specificity, psychiatric diagnosis, DSM-5 diagnostic criteria, rater experience
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Mental Disorders, Female, Humans, Interview, Psychological, Male, Middle Aged, Psychiatric Status Rating Scales, Psychometrics, Sensitivity and Specificity, Reproducibility of Results, Observer Variation, Diagnostic and Statistical Manual of Mental Disorders, Young Adult
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