The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Muscle time under tension during resistance exercise stimulates differential muscle protein sub‐fractional synthetic responses in men
Open accessAbstract
Non‐technical summary A single bout of resistance exercise stimulates the synthesis of new muscle proteins. Chronic performance of resistance exercise (i.e. weight training) is what makes your muscles grow bigger; a process known as hypertrophy. However, it is unknown if increasing the time that muscle is under tension will lead to greater increases in muscle protein synthesis. We report that leg extension exercise at 30% of the best effort (which is a load that is comparatively light), with a slow lifting movement (6 s up and 6 s down) performed to fatigue produces greater increases in rates of muscle protein synthesis than the same movement performed rapidly (1 s up and 1 s down). These results suggest that the time the muscle is under tension during exercise may be important in optimizing muscle growth; this understanding enables us to better prescribe exercise to those wishing to build bigger muscles and/or to prevent muscle loss that occurs with ageing or disease.
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Cites
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Progression Models in Resistance Training for Healthy Adults
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Mutation of the mouse klotho gene leads to a syndrome resembling ageing
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FUNCTIONAL SIGNIFICANCE OF CELL SIZE IN SPINAL MOTONEURONS
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Mixed muscle protein synthesis and breakdown after resistance exercise in humans
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Self-citationMoore, D. R., Robinson, M. J., Fry, J. L., Tang, J. E., Glover, E. I., Wilkinson, S. B., Prior, T., Tarnopolsky, M. A., & Phillips, S. M. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26401 · Cited by 973
Self-citationKumar, V., Selby, A., Rankin, D., Patel, R., Atherton, P., Hildebrandt, W., Williams, J., Smith, K., Seynnes, O., Hiscock, N., et al. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.164483 · Cited by 740 · cited 3×
“p70S6K, 4EBP-1, and p90RSK) well known to be phosphorylated immediately after resistance exercise (Kumar et al. 2009; Camera et al. 2010; Terzis et al. 2010; Moore et al. 2011) were also phosphorylated at 24 and 30 h post-exercise.”
BackgroundDreyer, H. C., Fujita, S., Cadenas, J. G., Chinkes, D. L., Volpi, E., & Rasmussen, B. B. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.113175 · Cited by 570 · cited 2×
“…phosphorylation was enhanced at 6 h post-exercise only in the CTL condition, a finding that is consistent with the notion that this signalling protein may be more responsive to feeding (Fujita et al. 2007a; Atherton et al. 2010; Moore et al. 2011) rather than contraction (Dreyer et al. 2006).”
BackgroundBurd, N. A., West, D. W. D., Staples, A. W., Atherton, P. J., Baker, J. M., Moore, D. R., Holwerda, A. M., Parise, G., Rennie, M. J., Baker, S. K., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012033 · Cited by 531
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Cited by
Sex differences in human fatigability: mechanisms and insight to physiological responses
Hunter, S. K. (2014) · Acta Physiologica · doi:10.1111/apha.12234 · Cited by 595
Areta, J. L., Burke, L. M., Ross, M. L., Camera, D. M., West, D. W. D., Broad, E. M., Jeacocke, N. A., Moore, D. R., Stellingwerff, T., Phillips, S. M., et al. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.244897 · Cited by 495
Self-citationSchoenfeld, B. J., Peterson, M. D., Ogborn, D., Contreras, B., & Sonmez, G. T. (2015) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000000958 · Cited by 418
Franchi, M. V., Atherton, P. J., Reeves, N. D., Flück, M., Williams, J., Mitchell, W. K., Selby, A., Beltran Valls, R. M., & Narici, M. V. (2014) · Acta Physiologica · doi:10.1111/apha.12225 · Cited by 389
Damas, F., Phillips, S. M., Libardi, C. A., Vechin, F. C., Lixandrão, M. E., Jannig, P. R., Costa, L. A. R., Bacurau, A. V., Snijders, T., Parise, G., et al. (2016) · The Journal of Physiology · doi:10.1113/jp272472 · Cited by 353
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Metadata
- Authors
- Burd, N. A., Andrews, R. J., West, D. W. D., Little, J. P., Cochran, A. J. R., Hector, A. J., Cashaback, J. G. A., Gibala, M. J., Potvin, J. R., Baker, S. K., & Phillips, S. M.
- Venue
- The Journal of Physiology
- Publisher
- Wiley
- Published
- 2012-01-15
- Volume
- 590
- Issue
- 2
- Pages
- 351-362
- ISSN
- 0022-3751 (ISSN-L)
- 1469-7793
- OpenAlex
- W2136662789
- Cited by
- 345
- References
- 22
- FWCI
- 5.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Burd, N. A., Andrews, R. J., West, D. W. D., Little, J. P., Cochran, A. J. R., Hector, A. J., Cashaback, J. G. A., Gibala, M. J., Potvin, J. R., Baker, S. K., & Phillips, S. M. (2012). Muscle time under tension during resistance exercise stimulates differential muscle protein sub‐fractional synthetic responses in men. The Journal of Physiology. https://doi.org/10.1113/jphysiol.2011.221200
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
