Cited by 239Probiotics and Fermented FoodsExercise and Physiological ResponsesPediatric health and respiratory diseases

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Daily Probiotic’s (Lactobacillus casei Shirota) Reduction of Infection Incidence in Athletes

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Gleeson, Michael, Bishop, Nicolette C., Oliveira, Marta, Tauler, Pedro·2011·International Journal of Sport Nutrition and Exercise Metabolism

DOI 10.1123/ijsnem.21.1.55

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Abstract

The purpose of this study was to examine the effects of a probiotic supplement during 4 mo of winter training in men and women engaged in endurance-based physical activities on incidence of upper respiratory-tract infections (URTIs) and immune markers. Eighty-four highly active individuals were randomized to probiotic ( n = 42) or placebo ( n = 42) groups and, under double-blind procedures, received probiotic (PRO: Lactobacillus casei Shirota [LcS]) or placebo (PLA) daily for 16 wk. Resting blood and saliva samples were collected at baseline and after 8 and 16 wk. Weekly training and illness logs were kept. Fifty-eight subjects completed the study ( n = 32 PRO, n = 26 PLA). The proportion of subjects on PLA who experienced 1 or more weeks with URTI symptoms was 36% higher than those on PRO (PLA 0.90, PRO 0.66; p = .021). The number of URTI episodes was significantly higher ( p < .01) in the PLA group (2.1 ± 1.2) than in the PRO group (1.2 ± 1.0). Severity and duration of symptoms were not significantly different between treatments. Saliva IgA concentration was higher on PRO than PLA, significant treatment effect F (1, 54) = 5.1, p = .03; this difference was not evident at baseline but was significant after 8 and 16 wk of supplementation. Regular ingestion of LcS appears to be beneficial in reducing the frequency of URTI in an athletic cohort, which may be related to better maintenance of saliva IgA levels during a winter period of training and competition.

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Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Statistical Power Analysis for the Behavioral Sciences (2nd ed.).
Lachenbruch, P. A., & Cohen, J. (1989) · Journal of the American Statistical Association · doi:10.2307/2290095 · Cited by 37,421
International physical activity questionnaire: 12-country reliability and validity
CRAIG, C. L., MARSHALL, A. L., SJ??STR??M, M., BAUMAN, A. E., BOOTH, M. L., AINSWORTH, B. E., PRATT, M., EKELUND, U., YNGVE, A., SALLIS, J. F., et al. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000078924.61453.fb · Cited by 21,619
Immune function in sport and exercise
Gleeson, M. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00008.2007 · Cited by 1,016
Self-citation
Effect of long term consumption of probiotic milk on infections in children attending day care centres: double blind, randomised trial
Hatakka, K., Savilahti, E., Pönkä, A., Meurman, J. H., Poussa, T., Näse, L., Saxelin, M., & Korpela, R. (2001) · BMJ · doi:10.1136/bmj.322.7298.1327 · Cited by 645
Infectious episodes in runners before and after the Los Angeles Marathon.
Nieman, D. C., Johanssen, L. M., Lee, J. W., & Arabatzis, K. (1990) · PubMed · Cited by 530
Probiotics and immunity
Borchers, A. T., Selmi, C. F., Meyers, F. J., Keen, C. L., & Gershwin, M. E. (2009) · Journal of Gastroenterology · doi:10.1007/s00535-008-2296-0 · Cited by 507
Exercise and Immune Function
Nieman, D. C., & Pedersen, B. K. (1999) · Sports Medicine · doi:10.2165/00007256-199927020-00001 · Cited by 466
Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria
Miettinen, M., Vuopio‐Varkila, J., & Varkila, K. (1996) · Infection and Immunity · doi:10.1128/iai.64.12.5403-5405.1996 · Cited by 402

Show all 45 references

Research works printed but not linked: 2

Peters, E.M., & Bateman, E.D. (1983). Ultramarathon running and URTI: An epidemiological survey. South African Medical Journal, 64(15), 582-584.
West, N.P., Pyne, D.B., Hopkins, W.G., Fricker, P.A., Jairath, A., Eskesen, D.C., & Cripps, A.W. (2009). Probiotic supplementation, illness and immunity in athletes. In Proceedings of the 9th International Society of Exercise and Immunology Symposium (p. 63). Tubingen, Germany: International Society for Exercise and Immunology.

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Mokarrami, A., Capacci, A., Trio, B., Merra, G., & Canosci, D. D. M. (2024) · Central European Journal of Sport Sciences and Medicine · doi:10.18276/cej.2024.1-03 · Cited by 4
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AKÇA, İ. H. (2018) · Ankara Üniversitesi Beden Eğitimi ve Spor Yüksekokulu SPORMETRE Beden Eğitimi ve Spor Bilimleri Dergisi · doi:10.1501/sporm_0000000365 · Cited by 4
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Roth, E., Schober-Halper, B., & Wessner, B. (2017) · Springer eBooks · doi:10.1007/978-3-7091-1591-6_10 · Cited by 2
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McManus, C., Murray, K., & Parry, D. A. (2017) · PubMed Central · Cited by 2
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Lacticaseibacillus paracasei strain Shirota suppresses upper respiratory tract infections and activates mononuclear phagocytic cells in healthy Japanese office workers: a randomized, double-blind, controlled trial
Naito, T., Morikawa, M., Ayaka, M. A. K. I., KATO-NAGAOKA, N., HAGIHIRA, Y., IWATA, A., WATANABE, O., Shida, K., Matsumoto, S., & Hori, T. (2025) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.2025-004 · Cited by 2
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Charitos, I. A., Marinelli, G., Inchingolo, A. D., Scacco, A., Calò, F., Ciocia, C., Inchingolo, F., Scacco, S., Palermo, A., Severino, M., et al. (2026) · Advances in Oral and Maxillofacial Surgery · doi:10.1016/j.adoms.2026.100670 · Cited by 1
Probiotics
Reid, G. (2013) · Springer eBooks · doi:10.1007/978-3-642-30144-5_89 · Cited by 1
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Aguilar, M., Giménez-Blasi, N., Latorre, J. A., Martı́nez-Bebiá, M., Bach-Faig, A., & Mariscal‐Arcas, M. (2021) · Archivos Latinoamericanos de Nutrición · doi:10.37527/2021.71.1.007 · Cited by 1
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Kim, J.-G., Cha, Y., Yang, S.-B., Kim, J.-Y., & Kim, K.-Y. (2022) · African Journal of Food Science · doi:10.5897/ajfs2022.2231 · Cited by 1
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Mazur-Kurach, P., Soboń, T., Klimek, A., Frączek, B., & Klimek-Jelonek, A. (2020) · Journal of Kinesiology and Exercise Sciences · doi:10.5604/01.3001.0014.7769 · Cited by 1
Probiotics in sports nutrition
Miles, M. P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85170-1.00024-5 · Cited by 1
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Wong, S. (2019) · City Research Online (City University London) · Cited by 1

Authors: Gleeson, M., Bishop, N. C., Oliveira, M., & Tauler, P.
Affiliations: Loughborough University (GB)
ORCID: Gleeson, Michael
Bishop, Nicolette C.
Oliveira, Marta
Tauler, Pedro
Venue: International Journal of Sport Nutrition and Exercise Metabolism
Publisher: Human Kinetics
Published: 2011-02
Volume: 21
Issue: 1
Pages: 55-64
ISSN: 1526-484X (ISSN-L)
1543-2742
DOI: 10.1123/ijsnem.21.1.55
OpenAlex: W2114489487
Cited by: 239
References: 45
Citations by year: 2026: 9 · 2025: 11 · 2024: 13 · 2023: 12 · 2022: 25 · 2021: 19 · 2020: 19 · 2019: 21 · 2018: 20 · 2017: 12 · 2016: 15 · 2015: 15 · 2014: 8 · 2013: 20 · 2012: 14
FWCI: 21.04
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: International Journal of Sport Nutrition and Exercise Metabolism (publishedVersion)
PubMed (publishedVersion)
Loughborough University Institutional Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
Loughborough University Research Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
Funders: Yakult Honsha
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric health and respiratory diseases
Keywords: probiotics, Lactobacillus casei Shirota, upper respiratory tract infection, athletes, endurance training, winter training, saliva IgA, immunological markers, infection incidence, immune function
MeSH terms: Adolescent, Adult, Double-Blind Method, Female, Humans, Immunoglobulins, Lacticaseibacillus casei, Male, Middle Aged, Respiratory Tract Infections, Saliva, Lymphocyte Subsets, Cytokines, Immunity, Mucosal, Probiotics, Gastrointestinal Tract, Young Adult, Athletes

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Daily Probiotic’s (Lactobacillus casei Shirota) Reduction of Infection Incidence in Athletes

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