Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L.-L., et al. (2003) · Nature · doi:10.1038/nature01960 · Cited by 3,796

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Imai, S.-I., Armstrong, C. M., Kaeberlein, M., & Guarente, L. (2000) · Nature · doi:10.1038/35001622 · Cited by 3,510

A central role for JNK in obesity and insulin resistance

Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., & Hotamisligil, G. S. (2002) · Nature · doi:10.1038/nature01137 · Cited by 3,359

Lazy Updating of hubs can enable more realistic models by speeding up stochastic simulations

Ehlert, K., & Loewe, L. (2014) · The Journal of Chemical Physics · doi:10.1063/1.4901114 · Cited by 6

Pharmacologic Means of Extending Lifespan

Lamming, D. W. (2012) · Journal of Clinical & Experimental Pathology · doi:10.4172/2161-0681.s4-002 · Cited by 6

Lipid Peroxidation: Aging Kidney

Harun, H. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.95801 · Cited by 6

Plausible Links Between Metabolic Networks, Stem Cells, and Longevity

Kucia, M., & Ratajczak, M. Z. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-31206-0_15 · Cited by 6

Nicotinamide riboside Induced Energy Stress and Metabolic Reprogramming in BEAS-2B Cells

Cordeiro, E. W. F., Marzola, E. L., Maekawa, R. S., dos Santos, M. R., Assunção, L. G., Massafera, M. P., de Oliveira, J., Batista, T. G. C., de Sales, M. C. O. P., Maria–Engler, S. S., et al. (2024) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.3c00312 · Cited by 5

Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes

Cen, Y., Curry, A. M., & White, D. S. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210531144629 · Cited by 6

Mitochondrial activity is the key to the protective effect of β-Lapachone, a NAD+ booster, in healthy cells against cisplatin cytotoxicity

Lin, S.-Y., Syu, J.-P., Lo, Y., Chau, Y., Don, M., Shy, H.-T., Lai, S.-M., & Kung, H. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154094 · Cited by 4

Resveratrol: A Sirtuin Activator and The Fountain of Youth

Meiliana, A., Dewi, N. M., & Wijaya, A. (2015) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v7i1.16 · Cited by 4

Can we use the epigenetic bioactivity of caloric restriction and phytochemicals to promote healthy ageing?

Christodoulou, M. S., Thomas, A., Poulain, S., Vidaković, M., Lahtela-Kakkonen, M. K., Matulis, D., Bertrand, P., Bártová, E., Blanquart, C., Mikros, E., et al. (2014) · MedChemComm · doi:10.1039/c4md00268g · Cited by 6

Extract of camellia seed cake ameliorates glycolipid metabolism disorder in mice through inhibiting ACOX1 activity

Chen, B., Li, M., Chen, X., Li, Z., Zhu, Q., Liu, C., He, H., Zhang, Z., Zhou, C., Liu, G., et al. (2025) · Food Chemistry X · doi:10.1016/j.fochx.2025.102707 · Cited by 4

Lactobacillus salivarius li01 alleviates premature ovarian insufficiency via gut microbiota-mediated modulation of tryptophan metabolism

Yao, L., Xie, S., Zhang, S., Ba, F., Jing, H., Qiu, B., Xu, L., Han, S., Xiao, H., Zhao, M., et al. (2026) · npj Science of Food · doi:10.1038/s41538-026-00823-6 · Cited by 4

Need for NAD+: Focus on Striated Muscle Laminopathies

Cardoso, D., & Muchir, A. (2020) · Cells · doi:10.3390/cells9102248 · Cited by 5

E1231/NMN protects against experimental metabolic syndrome: the central role of SIRT1 in modulating AKT/Nrf2/NFκB signaling

Elmorsy, E. A., Elashry, H. A., Alkhamiss, A. S., Alsaykhan, H., Hamad, R. S., Abdel‐Reheim, M. A., Alsoghair, M., Alharbi, M. S., Gabr, A. M., Ellethy, A. T., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1558709 · Cited by 4

Exploring mitochondrial dynamics and localization under cellular stress: A comprehensive insight

Agarwal, S., Karuppusamy, K. A., & Gupta, A. K. (2025) · Journal of Biosciences · doi:10.1007/s12038-025-00514-6 · Cited by 4

ANTI-OBESITY EFFECT OF RESVERATROL IN RATS ON HIGH FAT DIET THROUGH REGULATION OF GENE EXPRESSION OF VISCERAL WHITE ADIPOSE TISSUE

Mohamed, H. E., Asker, M. E.-S., Amin, R. S., & Eissa, R. G. (2016) · International Journal of Pharmacy and Pharmaceutical Sciences · Cited by 4

Metabolic Stress—Signaling and Metabolic Adaptation

Balakrishnan, P., Liebe, T., Amro, E. M., Dhaka, L., Heinzel, T., & Heller, R. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814253-0.00012-7 · Cited by 5

NAD+ as a Target for Cancer Treatment

Helman, T. J., & Braidy, N. (2023) · Springer eBooks · doi:10.1007/978-3-030-80962-1_269-1 · Cited by 4

Genome wide hypomethylation and youth-associated DNA gap reduction promoting DNA damage and senescence-associated pathogenesis

Watcharanurak, P., & Mutirangura, A. (2023) · Medical Research Archives · doi:10.18103/mra.v11i12.4952 · Cited by 4

Small molecules as activators in medicinal chemistry (2000–2016)

Hameed, A., al‐Rashida, M., Alharthy, R. D., Uroos, M., Mughal, E. U., Ali, S. A., & Khan, K. M. (2017) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2017.1349103 · Cited by 6

Sirtuin Activation by Small Molecules

Massudi, H., Wu, L. E., & Sinclair, D. A. (2016) · Springer eBooks · doi:10.1007/978-94-024-0962-8_12 · Cited by 4

Restoring NAD(+) Levels with NAD(+) Intermediates, the Second Law of Thermodynamics, and Aging Delay

Poljšak, B., & Milisav, I. (2018) · Rejuvenation Research · doi:10.1089/rej.2017.2037 · Cited by 4

Insulin resistance and SIRT1 dysregulation in neurodegenerative diseases

Shah, A., & Doshi, G. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103072 · Cited by 3

Simulation of Cellular Energy Restriction in Quiescence (ERiQ)—A Theoretical Model for Aging

Alfego, D., & Kriete, A. (2017) · Biology · doi:10.3390/biology6040044 · Cited by 3

Neurodegenerative Diseases and the Aging Brain

Godin, S. K., Seo, J., & Tsai, L. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811304-2.00017-1 · Cited by 3

NAD+: a crucial regulator of sirtuin activity in aging

Braidy, N., & Villalva, M. D. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00008-2 · Cited by 4

Resveralogues protect HepG2 cells against cellular senescence induced by hepatotoxic metabolites

Heidari, N., Sandeman, S. R., Dymond, M. K., Rodgers, C., Ostler, E. L., & Faragher, R. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.111938 · Cited by 3

Sex-specific modulation of cardiac fibrosis and lipid metabolism by B-vitamins in heart failure with reduced ejection fraction in mice

David, C., Deschênes, S., Ichkhan, G., Daneault, C., Frayne, I. R., Bouchard, B., Forest, A., Shi, Y. F., Higgins, M., Sirois, M. G., et al. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00841.2024 · Cited by 3

SIRT1 in Metabolic Health and Disease

Boutant, M., & Cantó, C. (2016) · Springer eBooks · doi:10.1007/978-94-024-0962-8_4 · Cited by 3

Targeting Endothelial SIRT1 for the Prevention of Arterial Aging

Guo, Y., & Wang, Y. (2018) · InTech eBooks · doi:10.5772/intechopen.73019 · Cited by 3

Dietary restriction and Sirtuin 1 in metabolic health: connections and divergences

Cantó, C. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665115003225 · Cited by 3

SIRT1 AS A KEY CELL REGULATOR OF METABOLISM AND OXIDATIVE STRESS

Voznesenskaya, T. Y., Stupchuk, M. S., Kaleinikova, O. N., & Блашків, Т. В. (2018) · Bulletin of Problems Biology and Medicine · doi:10.29254/2077-4214-2018-1-1-142-20-25 · Cited by 3

The development and emerging trends in Parkinson’s disease from the perspective of mitochondrial dysfunction: a bibliometric analysis using CiteSpace

Lu, Y., Chen, X., & Lai, Y. (2025) · Journal of Neurology · doi:10.1007/s00415-025-13472-8 · Cited by 2

GADD45β inhibits hepatic lipogenesis through the AMPK/SREBP1 pathway via reducing the ubiquitination-mediated degradation of SIRT1

Xiao, Y., Wang, R., Zhu, C., Wang, Q., Wang, X., Song, W., Li, S., Jiang, F., 桂定坤, Xu, Y., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-24864-1 · Cited by 2

The Hidden Players in Multiple Sclerosis Nutrition: A Narrative Review on the Influence of Vitamins, Polyphenols, Salt, and Essential Metals on Disease and Gut Microbiota

Rosso, R., Virgilio, E., Bronzini, M., Rolla, S., Maglione, A., & Clerico, M. (2026) · Nutrients · doi:10.3390/nu18010148 · Cited by 2

Nutritional Modulation of Melatonin‐SIRT1 Signaling by Octanoic Acid‐Rich Enteral Nutrition Protects Against Radiation‐Induced Intestinal Injury

Zhou, C., Li, X., Xing, C., & Cao, C. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71465 · Cited by 2

Neuroprotective Effects of Semaglutide in Cyclophosphamide-Induced Neuropathy: Restoring SIRT1/AMPK, PI3K/AKT/mTOR, and Antioxidant Pathways

Elbadawy, H. M., Almikhlafi, M. A., Saeedi, T. A., Alsubhi, M. H., Aljabri, A. A., Hussien, Y. A., Madani, M. E., Fayed, H. M., & Abdel-Rahman, R. F. (2026) · Journal of Molecular Neuroscience · doi:10.1007/s12031-026-02521-0 · Cited by 2

A Combination of Plant-Derived Extracts Modulates Nutrient-Responsive Metabolic Signalling in an In Vitro Gut–Liver–Adipose Model

Uberti, F., Galla, R., Mulè, S., Parini, F., & Molinari, C. (2026) · Nutrients · doi:10.3390/nu18091393 · Cited by 2

The role of the resveratrol-sirtuin axis in the treatment of metabolic dysfunction-associated diseases

Yang, J., Chen, S., Zeng, T., ZHANG, Y., Li, Z., & Li, H. (2026) · Exploration of Endocrine and Metabolic Diseases · doi:10.37349/eemd.2026.101470 · Cited by 2

In Vivo Measurement of the Acetylation State of Sirtuin Substrates as a Proxy for Sirtuin Activity

Dominy, J. E., Puigserver, P., & Cantó, C. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-637-5_15 · Cited by 2

The challenging role of micro-RNAs in non-alcoholic fatty liver disease in children with obesity: is it time for a new era?

Bartiromo, M., Nardolillo, M., Ferrara, S., Russo, G., del Giudice, E. M., & Sessa, A. D. (2023) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2023.2242245 · Cited by 2

Evaluation of the Role of PnuC Gene in Enhancing Nicotinamide Mononucleotide Synthesis

Vo, G. T. T., Nguyen, K. K. H., & Kim, B. S. (2025) · Biotechnology and Applied Biochemistry · doi:10.1002/bab.2713 · Cited by 2

Evolution, Possibilities, and Prospects for Application of the Methods of Assessment of Pyridine Nucleotides Pool for Studying Mechanisms of Brain Plasticity in Normal and Pathological Conditions

Zubova, A. V., Groshkov, A. A., Berdnikov, A. K., Novikova, S. V., Rozanova, N. A., Nikolaeva, L. V., Salmin, V. V., Kolotyeva, N. A., Хаспеков, Л. Г., Salmina, A. B., et al. (2025) · Biochemistry (Moscow) · doi:10.1134/s0006297924604477 · Cited by 2

Integrated Metabolomics and Lipidomics Analysis Reveals the Mechanism Behind the Action of Chiglitazar on the Protection Against Sepsis-Induced Acute Lung Injury

Lu, L.-L., Cao, Y.-L., Lu, Z.-C., Wu, H., Hu, S., Ye, B.-Q., He, J., Di, L., Chen, X., & Liu, Z. (2025) · Metabolites · doi:10.3390/metabo15050290 · Cited by 2

Traditional Plant Compounds for the Treatment of Neuropsychiatric Disorders

Din, I., Anwar, M., Rayees, S., & Malik, F. A. (2020) · Springer eBooks · doi:10.1007/978-981-15-1761-7_18 · Cited by 2

Epigenetic role of sirtuins in neurodegenerative brain disorders

Khanna, A., Anamika, A., & Trigun, S. K. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00009-4 · Cited by 3

Sirtuins and aging

Morris, B. J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00017-3 · Cited by 2

Sirtuins as Metabolic Modulators of Muscle Plasticity

Menzies, K. J., Zaldivar‐Jolissaint, J. F., & Auwerx, J. H. (2016) · Springer eBooks · doi:10.1007/978-94-024-0962-8_9 · Cited by 2

Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice

Méndez‐Lara, K. A., Santos, D., Farré, N., Nan, M. N., Pallarès, V., Pérez, A., Alonso, N., Escolá‐Gil, J. C., Blanco‐Vaca, F., & Julve, J. (2019) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2019.04.001 · Cited by 2

Aging and Cardiovascular Diseases: The Role of Cellular Senescence

Bozaykut, P. (2019) · Springer eBooks · doi:10.1007/978-981-13-8273-4_10 · Cited by 3

Inflammation métabolique et insulino-résistance : Les connaissances actuelles

Dali‐Youcef, N. (2015) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(15)30075-4 · Cited by 3

Multidisciplinary Analysis of the Metabolic Shift to Lactate Consumption in CHO Cell Culture

Zagari, F. (2012) · Infoscience (Ecole Polytechnique Fédérale de Lausanne) · doi:10.5075/epfl-thesis-5420 · Cited by 2

Intestinal epithelial differentiation and barrier function is promoted in vitro by a Cynara cardunculus L. leaf extract through AMPK pathway activation

Muscarà, C., Speciale, A., Molonia, M. S., Salamone, F. L., Saija, A., & Cimino, F. (2024) · Natural Product Research · doi:10.1080/14786419.2024.2384080 · Cited by 1

Interaction of early life stress and NAD + /SIRT1 pathway genetic risk promotes depression

Török, D., Krause, S., Gecse, K., Gál, Z., Eszlári, N., Csikos, M., Bagdy, G., Gonda, X., Juhász, G., & Petschner, P. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03733-5 · Cited by 1

Targeting the SARM1-NAD⁺ axis: A review of new strategy for reversing the imbalance of energy and mitochondrial homeostasis in metabolic diseases

Xiong, A., Lv, W., Shao, X., Lv, Y., & Zhang, Y. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108128 · Cited by 1

The Keto–Inflammatory Network: From Systems Biology to Biological Code

Ametaj, B. N. (2026) · Dairy · doi:10.3390/dairy7010019 · Cited by 2

L-Carvone as a Metabolic Enzyme Modulator in Doxorubicin Toxicity Induced Rat Tissue: A Combined Computational and Cardiac Slice Study

Nagarajan, A., & Doss, V. A. (2025) · EABR. Experimental and Applied Biomedical Research · doi:10.2478/eabr-2025-0022 · Cited by 1

The crosstalk between epigenetics and metabolism in the malignant cell

Țigu, A. B., Ivancuta, A., Constantinescu, C. S., Moisoiu, V., Grăjdieru, O., Cucoreanu, C., Nistor, M., Kegyes, D., Bancos, A., Tomacinschii, V., et al. (2026) · Discover Oncology · doi:10.1007/s12672-026-05082-1 · Cited by 2

Anhydrobiosis as a Model of Aging and Longevity: The Role of Autophagy and Metabolism in Yeast Cells

Jonnagiri, N. P. K. R., & Kieliszek, M. (2026) · Microbial Ecology · doi:10.1007/s00248-026-02782-7 · Cited by 1

Mechanotherapeutic biomaterials: Overcoming physical barriers to enhance intratumoral drug delivery in solid tumours

Singh, F. (2026) · Biomedical Microdevices · doi:10.1007/s10544-026-00832-y · Cited by 2

A Function-Centric Framework for Mitochondrial Quality Control

Ozcan, F., Vujovic, F., & Farahani, R. H. (2026) · Biomolecules · doi:10.3390/biom16081116 · Cited by 1

Review on the Effect of Resveratrol on Central Nervous System Disease

Dong, W., Zhou, Y., & Yang, Z. (2016) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2016.63014 · Cited by 1

The role of sirtuins in regulation of the ovarian function (a review)

Voznesenskaya, T. Y., & Блашків, Т. В. (2018) · Russian Journal of Human Reproduction · doi:10.17116/repro20182417-12 · Cited by 1

State of Knowledge and Recent Advances in Prevention and Treatment of Mitochondrial Dysfunction in Obesity and Type 2 Diabetes

Cantó, C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-811752-1.00017-1 · Cited by 1

Stress Response Pathways

Bhattacharya, S., & Rattan, S. I. S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11426-6 · Cited by 1

Molecular and Epigenetic Insights into RASSF1A Regulated Pathways in Inflammatory Bowel Disease

Salla, M. (2018) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3794195h · Cited by 1

In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1 -mutant lung cancerPreprint

Deng, J., Peng, D. H., Fenyö, D., Yuan, H., Lopez, A., Levin, D. S., Meynardie, M., Quinteros, M., Ranieri, M., Sahu, S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.04.18.537350 · Cited by 4

Lithocholic acid phenocopies rejuvenating and life-extending effects of calorie restrictionPreprint

Qu, Q., Chen, Y., Wang, Y., Long, S., Wang, W., Yang, H.-Y., Li, M., Tian, X., Wei, X., Liu, Y., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.07.570559 · Cited by 1

NAD+ boosting by oral nicotinamide mononucleotide administration regulates key metabolic and immune pathways through SIRT1 dependent and independent mechanisms to mitigate diet-induced obesity and dyslipidemia in micePreprint

Majeed, Y., Halabi, N. M., Engelke, R., Sarwath, H., Al-Noubi, M. N., Choi, S., Al-Malki, A., Agha, M. V., Vakayil, M., Chouchane, L., et al. (2025) · eLife · doi:10.7554/elife.109214 · Cited by 1

NAD+ boosting by oral nicotinamide mononucleotide administration regulates key metabolic and immune pathways through SIRT1 dependent and independent mechanisms to mitigate diet-induced obesity and dyslipidemia in micePreprint

Majeed, Y., Halabi, N. M., Engelke, R., Sarwath, H., Al-Noubi, M. N., Choi, S., Al-Malki, A., Agha, M. V., Vakayil, M., Chouchane, L., et al. (2025) · eLife · doi:10.7554/elife.109214.1 · Cited by 1

The Role of Altered Lipid Metabolism in Septic Myocardial Dysfunction

Siracusano, L., & Girasole, V. (2013) · InTech eBooks · doi:10.5772/51001

The [NAD[superscript +] over Sirtuin] Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Mouchiroud, L., Houtkooper, R. H., Moullan, N., Katsyuba, E., Ryu, D., Cantó, C., Mottis, A., Jo, Y.-S., Viswanathan, M., Schoonjans, K., et al. (2013) · DSpace@MIT (Massachusetts Institute of Technology)

Metabolic and cellular effects of calorie restriction and whey proteins in experimental obesity

Kurki, E. (2013) · Työväentutkimus Vuosikirja

Ischaemia-Reperfusion-Induced Kidney Injury : Experimental studies on the effects of caloric restriction, AMPK activator AICAR and α2-adrenoceptor agonists in the rat

Lempiäinen, J. (2014) · Työväentutkimus Vuosikirja

Regulació de l'heterocromatina constitutiva en condicions normals i d'estrès: Paper de SirT1 i d'HP1

Raurell‐Vila, H. (2014) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

UNVEILING THE METABOLIC NETWORK UNDERLYING MITOCHONDRIAL AND NUCLEAR METABOLISM IN A MODEL DIFFERENTIATING STEM CELL

Han, S. (2013) · Lu Zone Ul (Laurentian University)

Past and current topics on ADP-ribosylation reactions

Mennella, M. R. F. (2015) · Frontiers in bioscience · doi:10.2741/4317

Regulation of SIRT1, SIRT3, PGC-1α, and LRP130 in Response to Energetic Stress in Human Skeletal Muscle

Edgett, B. A. (2017) · QSpace (Queen's University Library)

Regulation of skeletal muscle energy/nutrient-sensing pathways during

Wijngaarden, M. A., van der Zon, G. C., van Dijk, K. W., Jazet, I. M., & Pijl, H. (2014)

Anti-aging supplementation with famvital system: influence on aging and health (clinico-pharmacological dossier, evidence-based medicine results)

Громова, О. А., Sorokina, M. A., Rachteenko, A. V., & Владимирович, Р. К. (2018) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2018-13-142-154

Tissue repair and stress responses of aged skin epidermis

Wong, W. (2020) · Digital Repository Service (Northeastern University) · doi:10.17760/d20383670

Scope to develop sirtuins modulators as a therapy to attenuate cardiac complications

Bugga, P., & Banerjee, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00018-5

Skeletal muscle health in aging

Grevendonk, L. (2021) · Research Publications (Maastricht University) · doi:10.26481/dis.20211006lg

Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice

Méndez‐Lara, K. A., Santos, D., Farré, N., Nan, M. N., Pallarès, V., Pérez, A., Alonso, N., Escolá‐Gil, J. C., Blanco‐Vaca, F., & Julve, J. (2019) · Clínica e Investigación en Arteriosclerosis (English Edition) · doi:10.1016/j.artere.2019.11.005

Ribosídeo de nicotinamida (NR), uma molécula doadora de NAD+, falha em ativar o metabolismo e retardar o envelhecimento em "Caenorhabditis elegans"

da Silva, G. T. (2020) · doi:10.47749/t/unicamp.2020.1128746

FACTORS INFLUENCING PERIPHERAL SKIN TEMPERATURE CIRCADIAN RHYTHM IN YOUNG ADULT MALES

Tranel, H. R. (2014) · UKnowledge (University of Kentucky)

Communication in miRNAs Between Inflammation and Cancer

Fujii, Y. R. (2023) · Springer eBooks · doi:10.1007/978-981-99-3165-1_7

NAD+ boosting by oral nicotinamide mononucleotide administration regulates key metabolic and immune pathways through SIRT1 dependent and independent mechanisms to mitigate diet-induced obesity and dyslipidemia in micePreprint

Majeed, Y., Halabi, N. M., Engelke, R., Sarwath, H., Al-Noubi, M. N., Choi, S., Al-Malki, A., Agha, M. V., Vakayil, M., Chouchane, L., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.20.660826

Genome-scale modeling reveals regulation of human metabolism by the histone deacetylase SIRT1Preprint

Pi, J. R., Alberto, J., Paoli, J., Baspinar, O., Guéant‐Rodriguez, R., Guéant, J., & Heinken, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.03.673976

Therapeutic Effect of LEV in a Propionic Acid‐Induced Autism Model via AMPK/SIRT1 Pathway

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NAD+ as a Target for Cancer Treatment

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Inherited retinal degenerations: PARP regulates calpain activation via TRPM2 channels in rd1 mouse photoreceptorsPreprint

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Metabolic health and intermittent fasting: implications for age-related disorders

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Additional file 2 of Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer

Sriramkumar, S., Sood, R., Huntington, T. D., Ghobashi, A. H., Vuong, T. T., Metcalfe, T. X., Wang, W., Nephew, K. P., & O’Hagan, H. M. (2022) · Figshare · doi:10.6084/m9.figshare.19947273

Additional file 1 of Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer

Sriramkumar, S., Sood, R., Huntington, T. D., Ghobashi, A. H., Vuong, T. T., Metcalfe, T. X., Wang, W., Nephew, K. P., & O’Hagan, H. M. (2022) · Figshare · doi:10.6084/m9.figshare.19947270

Lifelong cGAS deficiency leads to altered lipid storage and cholesterol homeostasis

Carrillanca, D., Riquelme, I., Mansilla-Jaramillo, M., Sánchez-Pérez, C., Monterroza, A., Lepio, N., Rojas, F., Cancino, G. I., & Murgas, P. (2026) · Biological Research · doi:10.1186/s40659-026-00669-y

Metabolic reprogramming and epigenetic effects due to reducing sugars and glycation products in cancer

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Poly(ADP-ribose) polymerase regulates transient receptor potential channel M2-dependent calpain activation in rd1 mouse retinal degeneration

Yan, J., Kong, L., Zhao, Z., Yang, Q., Wang, L., Yang, Q., Harteneck, C., Jiao, K., Hu, Z., & Paquet‐Durand, F. (2026) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-01102

Computational Repurposing of Nilotinib and Radotinib as SIRT2 Inhibitors for Neurodegenerative Diseases

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CARM1 phosphorylation prevents interaction between PRMT1 and CARM1, two <<protein arginine methyltransferases>> involved in proliferation in lung cancer

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SIRT1 in Metabolic Health and Disease

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Spatial Dynamics of SIRT1 Dictate Metabolic Transitions in the Cell Nucleus

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Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

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NAD+ as a Pharmacological Tool to Boost Sirtuin Activity

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