The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)

Green, A. Richard, Mechan, Annis O., Elliott, J. Martin, O’Shea, Esther, Colado, M. Isabel·2003·Pharmacological Reviews

DOI 10.1124/pr.55.3.3

Cited by (1,000)

Items 501–600 of 1,000

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Melanie Mueller, Frank T. Peters, George A. Ricaurte, Hans H. Maurer · 2007 · Journal of Chromatography B
MDMA (ecstasy) effects in pubescent rats: Males are more sensitive than females
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Nonaka, Ryouichi, Nagai, Fumiko, Ogata, Akio, Satoh, Kanako · 2007 · Biological and Pharmaceutical Bulletin
Effects of adenosine A2a receptor agonist and antagonist on hippocampal nuclear factor-kB expression preceded by MDMA toxicity
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Jessica J. Walsh, Daniel J. Christoffel, Xiaoting Wu, Matthew B. Pomrenze, Robert C. Malenka · 2020 · Current Opinion in Neurobiology
Role of the gut–brain axis via the subdiaphragmatic vagus nerve in stress resilience of 3,4-methylenedioxymethamphetamine in mice exposed to chronic restrain stress
Youge Qu, Akifumi Eguchi, Li Ma, Xiayun Wan, Chisato Mori, Kenji Hashimoto · 2023 · Neurobiology of Disease
Alcohol enhances the psychostimulant and conditioning effects of mephedrone in adolescent mice; postulation of unique roles of D3receptors and BDNF in place preference acquisition
Andrés Ciudad‐Roberts, Jorge Camarasa, Carlos J. Ciudad, David Pubill, Elena Escubedo · 2015 · British Journal of Pharmacology
Developmental exposure to 3,4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus
Kyung‐Ok Cho, Gyu‐Seek Rhee, Seung Jun Kwack, S.Y. Chung, Seong-Yun Kim · 2008 · Neuroscience
Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes
Helena Pontes, Carla Sousa, Renata Silva, Eduarda G. R. Fernandes, Helena Carmo, Fernando Remião, Félix Dias Carvalho, Maria de Lourdes Bastos · 2008 · Toxicology
Neuroimaging in Human MDMA (Ecstasy) Users
Ronald L. Cowan, Deanne M. Roberts, James M. Joers · 2008 · Annals of the New York Academy of Sciences
Direct Comparison of (±) 3,4-Methylenedioxymethamphetamine (“Ecstasy”) Disposition and Metabolism in Squirrel Monkeys and Humans
Melanie Mueller, Erin A Kolbrich, Frank T. Peters, Hans H. Maurer, Una D. McCann, Marilyn Ann Huestis, George A. Ricaurte · 2009 · Therapeutic Drug Monitoring
Increased CRE-binding activity and tryptophan hydroxylase mRNA expression induced by 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in the rat frontal cortex but not in the hippocampus
Ana García‐Osta, Joaquı́n Del Rı́o, Diana Frechilla · 2004 · Molecular Brain Research
Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA
Sami Ben Hamida, Antoine Tracqui, Anne Pereira de Vasconcelos, Esther Szwarc, Christine Lazarus, Christian R. Kelche, Byron C. Jones, Jean‐Christophe Cassel · 2008 · The International Journal of Neuropsychopharmacology
Behavioral, hyperthermic and pharmacokinetic profile of para-methoxymethamphetamine (PMMA) in rats
Tomáš Páleníček, Marie Balı́ková, Miroslava Rohanová, Tomáš Novák, Jiřı́ Horáček, Michaela Fujáková, Cyril Höschl · 2010 · Pharmacology Biochemistry and Behavior
A novel MDMA analogue, UWA‐101, that lacks psychoactivity and cytotoxicity, enhances l ‐DOPA benefit in parkinsonian primates
Tom H. Johnston, Zak A. Millar, Philippe Huot, Keith Wagg, Sherri L. Thiele, Danielle Salomonczyk, C. J. Yong-Kee, Michael N. Gandy, Matthew J. McIldowie, Katie D. Lewis et al. · 2012 · The FASEB Journal
Metformin Prevented Dopaminergic Neurotoxicity Induced by 3,4-Methylenedioxymethamphetamine Administration
Pier Francesca Porceddu, Ismail Ogunbayode Ishola, Liliana Contu, Micaela Morelli · 2016 · Neurotoxicity Research
Locomotor and pyretic effects of MDMA–ethanol associations in rats
Jean‐Christophe Cassel, Hélène Jeltsch‐David, Julie Koenig, Byron C. Jones · 2004 · Alcohol
A PET study of effects of chronic 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) on serotonin markers in Göttingen minipig brain
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High concentrations of MDMA (‘ecstasy’) and its metabolite MDA inhibit calcium influx and depolarization-evoked vesicular dopamine release in PC12 cells
Laura Hondebrink, Jan Meulenbelt, Marieke Meijer, Martin van den Berg, Remco H.S. Westerink · 2011 · Neuropharmacology
Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats
Erica Shen, Syed F. Ali, Jerrold S. Meyer · 2011 · Neuropharmacology
Event related potential (ERP) evidence for selective impairment of verbal recollection in abstinent recreational methylenedioxymethamphetamine (“Ecstasy”)/polydrug users
Adrian Burgess, Louise Venables, Helena Jones, Rhiannon G. Edwards, Andrew C. Parrott · 2011 · Psychopharmacology
Progression and Persistence of Neurotoxicity Induced by MDMA in Dopaminergic Regions of the Mouse Brain and Association with Noradrenergic, GABAergic, and Serotonergic Damage
Giulia Costa, Micaela Morelli, Nicola Simola · 2017 · Neurotoxicity Research
Gas chromatography–ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine
Daniel Gomes, Paula Guedes de Pinho, Helena Pontes, Luísa Maria Ferreira, Paula S. Branco, Fernando Remião, Félix Dias Carvalho, Maria de Lourdes Bastos, Helena Carmo · 2010 · Journal of Chromatography B
Investigating the Role of Serotonin in Visual Orientation Processing Using an ‘Ecstasy’ (MDMA)-Based Research Model
Clare Dickson, Raimondo Bruno, John Brown · 2009 · Neuropsychobiology
A mechanistic insight into 3,4-methylenedioxymethamphetamine (“ecstasy”)-mediated hepatotoxicity
Irene Antolino-Lobo, Jan Meulenbelt, Martin van den Berg, Majorie B.M. van Duursen · 2011 · Veterinary Quarterly
Acute and long-term effects of a single dose of MDMA on aggression in Dark Agouti rats
Eszter Kirilly, Anita Benkő, Linda Ferrington, Rómeó D. Andó, Paul A. T. Kelly, György Bagdy · 2005 · The International Journal of Neuropsychopharmacology
Studies of (±)-3,4-Methylenedioxymethamphetamine (MDMA) Metabolism and Disposition in Rats and Mice: Relationship to Neuroprotection and Neurotoxicity Profile
Melanie Mueller, Concepción Maldonado Adrián, Jie Yuan, Una D. McCann, George A. Ricaurte · 2012 · Journal of Pharmacology and Experimental Therapeutics
Neurochemical and Neurotoxic Effects of MDMA (Ecstasy) and Caffeine After Chronic Combined Administration in Mice
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Bioanalytical methods for determining ecstasy components in biological matrices: A review
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Mice with Decreased Cerebral Dopamine Function following a Neurotoxic Dose of MDMA (3,4-Methylenedioxymethamphetamine, “Ecstasy”) Exhibit Increased Ethanol Consumption and Preference
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Reduced sensitivity to MDMA-induced facilitation of social behaviour in MDMA pre-exposed rats
Thompson, Murray R., Callaghan, Paul D., Hunt, Glenn E., McGregor, Iain S. · 2008 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
MDMA ('Ecstasy'), oxytocin and vasopressin modulate social preference in rats: a role for handling and oxytocin receptors
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Vesicular Monoamine Transporter 2 and the Acute and Long-Term Response to 3,4-(±)-Methylenedioxymethamphetamine
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Cognitive Effects of MDMA in Laboratory Animals: A Systematic Review Focusing on Dose
Madeline Marie Pantoni, Stephan Anagnostaras · 2019 · Pharmacological Reviews
Repeated use of 3,4-methylenedioxymethamphetamine is associated with the resilience in mice after chronic social defeat stress: A role of gut–microbiota–brain axis
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Effect of a serotonin depleting regimen of 3,4-methylenedioxymethamphetamine (MDMA) on the subsequent stimulation of acetylcholine release in the rat prefrontal cortex
Sunila G Nair, Gary A. Gudelsky · 2006 · Brain Research Bulletin
Motor cortex and corticospinal excitability in humans with a history of illicit stimulant use
Stanley C. Flavel, Jason M. White, Gabrielle Todd · 2012 · Journal of Applied Physiology
Prior MDMA (Ecstasy) use is associated with increased basal ganglia–thalamocortical circuit activation during motor task performance in humans: An fMRI study
John Karageorgiou, Mary S. Dietrich, Evonne J. Charboneau, Neil D. Woodward, Jennifer Urbano Blackford, Ronald M. Salomon, Ronald L. Cowan · 2009 · NeuroImage
The Psychopharmacology of ±3,4 Methylenedioxymethamphetamine and its Role in the Treatment of Posttraumatic Stress Disorder
Timothy Amoroso · 2015 · Journal of Psychoactive Drugs
Comparative effects of amphetamine-like psychostimulants on rat hippocampal cell genesis at different developmental ages
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Repeated MDMA administration increases MDMA-produced locomotor activity and facilitates the acquisition of MDMA self-administration: role of dopamine D2 receptor mechanisms.
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MDMA modifies active avoidance learning and recall in mice
José Manuel Trigo, Araceli Cabrero-Castel, Fernando Berrendero, Rafael J. Maldonado, Patricia Robledo · 2008 · Psychopharmacology
Ethanol co-administration moderates 3,4-methylenedioxymethamphetamine effects on human physiology
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Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days
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Human Ecstasy Use is Associated with Increased Cortical Excitability: An fMRI Study
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Ultrastructural characterization of tryptophan hydroxylase 2-specific cortical serotonergic fibers and dorsal raphe neuronal cell bodies after MDMA treatment in rat
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Effects of ethanol and ecstasy on conditioned place preference in the rat
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Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure
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Chronic MDMA induces neurochemical changes in the hippocampus of adolescent and young adult rats: Down-regulation of apoptotic markers
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Age-dependent (+)MDMA-mediated Neurotoxicity in Mice
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Psychiatric Disorders and Their Correlates Among Young Adult MDMA Users in Ohio
Rüssel S. Falck, Robert Gideon Carlson, Jichuan Wang, Harvey Alan Siegal · 2006 · Journal of Psychoactive Drugs
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Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats
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Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits
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