The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
Green, A. Richard, Mechan, Annis O., Elliott, J. Martin, O’Shea, Esther, Colado, M. Isabel·2003·Pharmacological Reviews
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- A Metabolomics Study of Retrospective Forensic Data from Whole Blood Samples of Humans Exposed to 3,4-Methylenedioxymethamphetamine: A New Approach for Identifying Drug Metabolites and Changes in Metabolism Related to Drug ConsumptionKirstine Lykke Nielsen, Rasmus Telving, Mette Findal Andreasen, Jørgen Bo Hasselstrøm, Mogens Johannsen · 2015 · Journal of Proteome Research
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- Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine (‘Ecstasy’) cytotoxicityHelena Carmo, Marc Brulport, Matthias Hermes, Franz Oesch, Renata Silva, Luísa Maria Ferreira, Paula S. Branco, Douwe de Boer, Fernando Remião, Félix Dias Carvalho et al. · 2006 · Pharmacogenetics and Genomics
- Cannabis Coadministration Potentiates the Effects of “Ecstasy” on Heart Rate and Temperature in HumansGlenn Dumont, Cornelis Kramers, Fred C.G.J. Sweep, Daan Johannes Touw, J. G. Coen van Hasselt, M. de Kam, J M van Gerven, Jan K. Buitelaar, Robbert Jan Verkes · 2009 · Clinical Pharmacology & Therapeutics
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- Development and validation of a disk solid phase extraction and gas chromatography–mass spectrometry method for MDMA, MDA, HMMA, HMA, MDEA, methamphetamine and amphetamine in sweatBruno Spinosa De Martinis, Allan J. Barnes, Karl B. Scheidweiler, Marilyn Ann Huestis · 2007 · Journal of Chromatography B
- Spinal 5-HT2A receptors regulate cutaneous sympathetic vasomotor outflow in rabbits and rats; relevance for cutaneous vasoconstriction elicited by MDMA (3,4-methylenedioxymethamphetamine, “Ecstasy”) and its reversal by clozapineYouichirou Ootsuka, Eugene Nalivaiko, William Walter Blessing · 2004 · Brain Research
- Differential effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) on BDNF mRNA expression in rat frontal cortex and hippocampusRebeca Martínez-Turrillas, Sonia Moyano, Joaquı́n Del Rı́o, Diana Frechilla · 2006 · Neuroscience Letters
- Enzymatic–nonenzymatic cellular antioxidant defense systems response and immunohistochemical detection of MDMA, VMAT2, HSP70, and apoptosis as biomarkers for MDMA (Ecstasy) neurotoxicityIrene Riezzo, Daniela Cerretani, Carmela Fiore, Stefania Bello, Fabio Centini, Stefano D’Errico, Anna Ida Fiaschi, Giorgio Giorgi, Margherita Neri, Cristoforo Pomara et al. · 2009 · Journal of Neuroscience Research
- Critical Role of Peripheral Vasoconstriction in Fatal Brain Hyperthermia Induced by MDMA (Ecstasy) under Conditions That Mimic Human Drug UseEugene A. Kiyatkin, A. H. Kim, Ken T. Wakabayashi, Michael H. Baumann, Yavin Shaham · 2014 · Journal of Neuroscience
- Differential effects of MDMA and scopolamine on working versus reference memory in the radial arm maze taskC. Kay, David N. Harper, Maree J. Hunt · 2009 · Neurobiology of Learning and Memory
- Sub-chronic nandrolone treatment modifies neurochemical and behavioral effects of amphetamine and 3,4-methylenedioxymethamphetamine (MDMA) in ratsSanna Kurling, Aino Kankaanpää, Timo Seppαlä · 2008 · Behavioural Brain Research
- The Influence of Genetic and Environmental Factors among MDMA Users in Cognitive PerformanceElisabet Cuyàs, Antonio Verdejo‐García, Ana Beatriz Fagundo, Olha Khymenets, Joan Carles Rodríguez, Aida Cuenca‐Royo, Susana de Sola Llopis, Klaus Langohr, Jordi Peña‐Casanova, Marta Torrens et al. · 2011 · PLoS ONE
- Role of the Dopaminergic System in the Acquisition, Expression and Reinstatement of MDMA-Induced Conditioned Place Preference in Adolescent MiceAntonio Vidal‐Infer, C. Roger-Sánchez, Manuel Daza‐Losada, M.A. Aguilar, José Miñarro, Marta Rodríguez‐Arias · 2012 · PLoS ONE
- Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brainAnna M. S. Kindlundh-Högberg, Per Svenningsson, H. B. Schiöth · 2006 · Neuropharmacology
- Deaths involving serotonergic drugsJ. L. Pilgrim, Dimitri Gerostamoulos, Olaf H. Drummer · 2010 · Forensic Science International
- NMDA receptor subunit and CaMKII changes in rat hippocampus induced by acute MDMA treatment: a mechanism for learning impairmentSonia Moyano, Diana Frechilla, J. Del R�o · 2004 · Psychopharmacology
- Ethanol, 3,4-Methylenedioxymethamphetamine (Ecstasy) and Their Combination: Long-Term Behavioral, Neurochemical and Neuropharmacological Effects in the RatJean‐Christophe Cassel, Céline Riegert, Susanne Rutz, Julie Koenig, Katharina Rothmaier, Brigitte Cosquer, Christine Lazarus, Anja Birthelmer, Hélène Jeltsch‐David, Byron C. Jones et al. · 2005 · Neuropsychopharmacology
- Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in miceNadia Benturquia, Cindie Courtin, Florence Noble, Cynthia Marie-claire A · 2008 · Brain Research
- Microglial and astroglial activation by 3,4‐methylenedioxymethamphetamine ( MDMA ) in mice depends on S(+) enantiomer and is associated with an increase in body temperature and motilityLucia Frau, Nicola Simola, Antonio Plumitallo, Micaela Morelli · 2012 · Journal of Neurochemistry
- Phosphodiesterase 5 inhibitors prevent 3,4‐methylenedioxymethamphetamine‐induced 5‐HT deficits in the ratElena Puerta, Isabel Hervías, Beatriz Goñi‐Allo, Berta Lasheras, Joaquı́n Jordán, Norberto Aguirre · 2008 · Journal of Neurochemistry
- Cardiovascular toxicity of novel psychoactive drugs: Lessons from the pastPatrick Dawson, James D. Moffatt · 2012 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- The profile of mephedrone on human monoamine transporters differs from 3,4-methylenedioxymethamphetamine primarily by lower potency at the vesicular monoamine transporterChristian Pifl, Harald Reither, Oleh Hornykiewicz · 2015 · European Journal of Pharmacology
- Effects of 3,4‐methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicityDominik K. Biezonski, Jerrold S. Meyer · 2009 · Journal of Neurochemistry
- Comparative Effects of Substituted Amphetamines (PMA, MDMA, and METH) on Monoamines in Rat CaudateB. Gough, Syed Z. Imam, Bruce E. Blough, William Slikker, Syed F. Ali · 2002 · Annals of the New York Academy of Sciences
- The relationship between core body temperature and 3,4-methylenedioxymethamphetamine metabolism in rats: implications for neurotoxicityBeatriz Goñi‐Allo, Brian Ó. Mathúna, Mireia Segura, Elena Puerta, Berta Lasheras, Rafael de la Torre, Norberto Aguirre · 2007 · Psychopharmacology
- Chronic exposure to ethanol exacerbates MDMA-induced hyperthermia and exposes liver to severe MDMA-induced toxicity in CD1 miceHelena Pontes, José Alberto Duarte, Paula Guedes de Pinho, Maria Elisa Soares, Eduarda G. R. Fernandes, Ricardo Jorge Dinis‐Oliveira, Carla Sousa, Renata Silva, Helena Carmo, Susana I.P. Casal et al. · 2008 · Toxicology
- MDMA (‘Ecstasy’) and methamphetamine combined: Order of administration influences hyperthermic and long-term adverse effects in female ratsKelly J. Clemens, Jennifer Louise Cornish, Kong M. Li, Glenn E. Hunt, Iain S. McGregor · 2005 · Neuropharmacology
- CB1Cannabinoid Receptor Modulates 3,4-Methylenedioxymethamphetamine Acute Responses and ReinforcementClara Touriño, Catherine A. Ledent, Rafael J. Maldonado, Olga Valverde · 2007 · Biological Psychiatry
- Partial lesion of the serotonergic system by a single dose of MDMA results in behavioural disinhibition and enhances acute MDMA-induced social behaviour on the social interaction testRómeó D. Andó, Anita Benkő, Linda Ferrington, Eszter Kirilly, Paul A.T. Kelly, György Bagdy · 2006 · Neuropharmacology
- Proton magnetic resonance spectroscopy in ecstasy (MDMA) usersJörg Daumann, Thomas Fischermann, Ulrich Pilatus, Armin K. Thron, Walter Moeller‐Hartmann, Euphrosyne Gouzoulis‐Mayfrank · 2004 · Neuroscience Letters
- Multiple molecular and neuropharmacological effects of MDMA (Ecstasy)Rabi Simantov · 2003 · Life Sciences
- Depressive symptomatology in young adults with a history of MDMA use: a longitudinal analysisRüssel S. Falck, Jichuan Wang, Robert Gideon Carlson · 2007 · Journal of Psychopharmacology
- Differential involvement of prelimbic and infralimbic medial prefrontal cortex in discrete cue-induced reinstatement of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) seeking in ratsKevin T. Ball, Mylissa M. Slane · 2012 · Psychopharmacology
- Treatment with MDMA from P11–20 disrupts spatial learning and path integration learning in adolescent rats but only spatial learning in older ratsMatthew R. Skelton, Michael T. Williams, Charles V. Vorhees · 2006 · Psychopharmacology
- PARADOXICAL FACILITATION: THE RESOLUTION OF FOREIGN ACCENT SYNDROME AFTER CEREBELLAR STROKED. A. Cohen, Kathleen Mary Kurowski, Megan S. Steven, Sheila E. Blumstein, A. Pascual-Leone · 2009 · Neurology
- Development and Characterization of a Novel Animal Model of Intermittent MDMA (“Ecstasy”) Exposure during AdolescenceJerrold S. Meyer, Brian J. Piper, Valerie E. Vancollie · 2008 · Annals of the New York Academy of Sciences
- High ambient temperature increases 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”)-induced Fos expression in a region-specific mannerGarth A. Hargreaves, Glenn E. Hunt, Jennifer Louise Cornish, Iain S. McGregor · 2007 · Neuroscience
- Altered brain activity and functional connectivity after MDMA-assisted therapy for post-traumatic stress disorderS. Parker Singleton, Julie B. Wang, Michael C. Mithoefer, Colleen A. Hanlon, Mark S. George, Annie Mithoefer, Oliver J. Mithoefer, Allison R. Coker, Berra Yazar‐Klosinski, Amy Emerson et al. · 2023 · Frontiers in Psychiatry
- Methamphetamine and 3,4-methylenedioxymethamphetamine interact with central nicotinic receptors and induce their up-regulationSara Garcia‐Ratés, Jordi Camarasa, Elena Escubedo, David Pubill · 2007 · Toxicology and Applied Pharmacology
- Involvement of mitochondrial/lysosomal toxic cross-talk in ecstasy induced liver toxicity under hyperthermic conditionJalal Pourahmad, Mohammad Reza Eskandari, Masoumeh Nosrati, Farzad Kobarfard, Ali Reza Khajeamiri · 2010 · European Journal of Pharmacology
- Evidence that MDMA (‘ecstasy’) increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brainElisa Torres, María Dolores Gutiérrez‐López, Érika Borcel, Inés Peraile, Andrea Mayado, Esther O’Shea, María Isabel Colado · 2010 · Journal of Neurochemistry
- Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HTAltaf S. Darvesh, Gary A. Gudelsky · 2005 · Brain Research
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- Memantine prevents MDMA-induced neurotoxicityCarlos Chipana, Jorge Camarasa, David Pubill, Elena Escubedo · 2007 · NeuroToxicology
- Endocrine and Neurochemical Effects of 3,4-Methylenedioxymethamphetamine and Its Stereoisomers in Rhesus MonkeysKevin Sean Murnane, William Edward Fantegrossi, J.R. Godfrey, Matthew L. Banks, Leonard Lee Howell · 2010 · Journal of Pharmacology and Experimental Therapeutics
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- Neuropsychotoxicity of Abused Drugs: Molecular and Neural Mechanisms of Neuropsychotoxicity Induced by Methamphetamine, 3,4-Methylenedioxymethamphetamine (Ecstasy), and 5-Methoxy-N,N-diisopropyltryptamine (Foxy)Takayuki Nakagawa, Shuji Kaneko · 2008 · Journal of Pharmacological Sciences
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- The hidden side of drug action: brain temperature changes induced by neuroactive drugsEugene A. Kiyatkin · 2012 · Psychopharmacology
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- Paroxetine Inhibits Acute Effects of 3,4-Methylenedioxymethamphetamine on the Immune System in HumansRoberta Pacifici, Simona Pichini, Piergiorgio Zuccaro, Magı́ Farré, Mireia Segura, Jordi Ortuño, Simonetta Di Carlo, Antonella Bacosi, Pere Nolasc Roset, Jordi Segura et al. · 2004 · Journal of Pharmacology and Experimental Therapeutics
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- Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent ratsAnna M. S. Kindlundh-Högberg, Anna Blomqvist, Rana Malki, Helgi B. Schiöth · 2008 · BMC Neuroscience
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