ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Sun, L., Wu, J., Du, F., Chen, X., & Chen, Z. J. (2013) · Science · doi:10.1126/science.1232458 · Cited by 4,996 · see citing works

Immunogenic cell death in cancer and infectious disease

Galluzzi, L., Buqué, A., Kepp, O., Zitvogel, L., & Kroemer, G. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2016.107 · Cited by 3,119 · see citing works

Dendritic cells in cancer immunology and immunotherapy

Wculek, S. K., Cueto, F. J., Mujal, A. M., Melero, I., Krummel, M. F., & Sancho, D. (2019) · Nature reviews. Immunology · doi:10.1038/s41577-019-0210-z · Cited by 2,594 · see citing works

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Deng, L., Liang, H., Xu, M., Yang, X., Burnette, B., Arina, A., Li, X.-D., Mauceri, H., Beckett, M., Darga, T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.10.019 · Cited by 2,182 · see citing works

Necroptosis and its role in inflammation

Pasparakis, M., & Vandenabeele, P. (2015) · Nature · doi:10.1038/nature14191 · Cited by 2,148 · see citing works

Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice

Deng, L., Liang, H. L., Burnette, B., Beckett, M., Darga, T. E., Weichselbaum, R. R., & Fu, Y. (2014) · Journal of Clinical Investigation · doi:10.1172/jci67313 · Cited by 2,101 · see citing works

Mitochondrial DNA stress primes the antiviral innate immune response

West, A. P., Khoury-Hanold, W., Staron, M., Tal, M. C., Pineda, C. M., Lang, S. M., Bestwick, M., Duguay, B. A., Raimundo, N., MacDuff, D. A., et al. (2015) · Nature · doi:10.1038/nature14156 · Cited by 1,975 · see citing works

cGAS surveillance of micronuclei links genome instability to innate immunity

Mackenzie, K. J., Carroll, P., Martin, C.-A., Murina, O., Fluteau, A., Simpson, D. J., Olova, N., Sutcliffe, H., Rainger, J. K., Leitch, A., et al. (2017) · Nature · doi:10.1038/nature23449 · Cited by 1,752 · see citing works

The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy

Bruni, D., Angell, H. K., & Galon, J. (2020) · Nature reviews. Cancer · doi:10.1038/s41568-020-0285-7 · Cited by 1,586 · see citing works

Mitotic progression following DNA damage enables pattern recognition within micronuclei

Harding, S. M., Benci, J. L., Irianto, J., Discher, D. E., Minn, A. J., & Greenberg, R. A. (2017) · Nature · doi:10.1038/nature23470 · Cited by 1,508 · see citing works

Cytoplasmic chromatin triggers inflammation in senescence and cancer

Dou, Z., Ghosh, K., Vizioli, M. G., Zhu, J., Sen, P., Wangensteen, K. J., Simithy, J., Lan, Y., Lin, Y., Zhou, Z., et al. (2017) · Nature · doi:10.1038/nature24050 · Cited by 1,335 · see citing works

The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

Li, T., & Chen, Z. J. (2018) · Journal of Experimental Medicine · doi:10.1084/jem.20180139 · Cited by 1,293 · see citing works

The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer

Kwon, J., & Bakhoum, S. F. (2020) · Cancer Discovery · doi:10.1158/2159-8290.cd-19-0761 · Cited by 1,293 · see citing works

cGAS in action: Expanding roles in immunity and inflammation

Ablasser, A., & Chen, Z. J. (2019) · Science · doi:10.1126/science.aat8657 · Cited by 1,077 · see citing works

Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

Sistigu, A., Yamazaki, T., Vacchelli, E., Chaba, K., Enot, D. P., Adam, J., Vitale, I., Goubar, A., Baracco, E. E., Remédios, C., et al. (2014) · Nature Medicine · doi:10.1038/nm.3708 · Cited by 1,042 · see citing works

Harnessing innate immunity in cancer therapy

Demaria, O., Cornen, S., Daëron, M., Morel, Y., Medzhitov, R., & Vivier, E. (2019) · Nature · doi:10.1038/s41586-019-1593-5 · Cited by 957 · see citing works

Inflammatory microenvironment remodelling by tumour cells after radiotherapy

McLaughlin, M., Patin, E. C., Pedersen, M., Wilkins, A. C., Dillon, M. T., Melcher, A. A., & Harrington, K. J. (2020) · Nature reviews. Cancer · doi:10.1038/s41568-020-0246-1 · Cited by 901 · see citing works

PARP inhibitor efficacy depends on CD8(+) T-cell recruitment via intratumoral STING pathway activation in BRCA-deficient models of triple-negative breast cancer

Pantelidou, C., Sonzogni, O., De Oliveria Taveira, M., Mehta, A. K., Kothari, A., Wang, D., Visal, T., Li, M. K., Pinto, J., Castrillon, J. A., et al. (2019) · Cancer Discovery · doi:10.1158/2159-8290.cd-18-1218 · Cited by 743 · see citing works

Necroptosis: Mechanisms and Relevance to Disease

Galluzzi, L., Kepp, O., Chan, F. K.-M., & Kroemer, G. (2016) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-052016-100247 · Cited by 721 · see citing works

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

Gong, Y.-N., Guy, C., Olauson, H., Becker, J. U., Yang, M., Fitzgerald, P., Linkermann, A., & Green, D. R. (2017) · Cell · doi:10.1016/j.cell.2017.03.020 · Cited by 689 · see citing works

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8 + T cells

Yatim, N., Jusforgues-Saklani, H., Orozco, S. L., Schulz, O., da Silva, R. B., Sousa, C. R. E., Green, D. R., Oberst, A., & Albert, M. L. (2015) · Science · doi:10.1126/science.aad0395 · Cited by 625 · see citing works

The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression

Seifert, L., Werba, G., Tiwari, S., Ly, N. N. G., Alothman, S., Alqunaibit, D., Avanzi, A., Barilla, R., Daley, D., Greco, S. H., et al. (2016) · Nature · doi:10.1038/nature17403 · Cited by 606 · see citing works

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

Zhang, T., Yin, C., Boyd, D. F., Quarato, G., Ingram, J. P., Shubina, M., Ragan, K. B., Ishizuka, T., Crawford, J. C., Tummers, B., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.050 · Cited by 551 · see citing works

Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

Benci, J. L., Johnson, L. R., Choa, R., Xu, Y., Qiu, J., Zhou, Z., Xu, B., Ye, D., Nathanson, K. L., June, C. H., et al. (2019) · Cell · doi:10.1016/j.cell.2019.07.019 · Cited by 541 · see citing works

Radiotherapy combination opportunities leveraging immunity for the next oncology practice

Herrera, F. G., Bourhis, J., & Coukos, G. (2016) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21358 · Cited by 511 · see citing works

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders

Andreeva, L., Hiller, B., Kostrewa, D., Lässig, C., de Oliveira Mann, C. C., Jan Drexler, D., Maiser, A., Gaidt, M., Leonhardt, H., Hornung, V., et al. (2017) · Nature · doi:10.1038/nature23890 · Cited by 511 · see citing works

Recent Developments in Radiotherapy

Citrin, D. E. (2017) · New England Journal of Medicine · doi:10.1056/nejmra1608986 · Cited by 496 · see citing works

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

Jiao, H., Wachsmuth, L., Kumari, S., Schwarzer, R., Lin, J., Eren, R. O., Fisher, A. D., Lane, R. K., Young, G. R., Kassiotis, G., et al. (2020) · Nature · doi:10.1038/s41586-020-2129-8 · Cited by 493 · see citing works

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance

Liang, H. L., Deng, L., Hou, Y., Meng, X., Huang, X., Rao, E., Zheng, W., Mauceri, H. J., Mack, M., Xu, M. M., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01566-5 · Cited by 491 · see citing works

DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

Thapa, R. J., Ingram, J. P., Ragan, K. B., Nogusa, S., Boyd, D. F., Benitez, A. A., Sridharan, H., Kosoff, R. E., Shubina, M., Landsteiner, V. J., et al. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.09.014 · Cited by 409 · see citing works

Necroptosis microenvironment directs lineage commitment in liver cancer

Seehawer, M., Heinzmann, F., D’Artista, L., Harbig, J., Roux, P.-F., Hoenicke, L., Dang, H., Klotz, S., Robinson, L., Doré, G., et al. (2018) · Nature · doi:10.1038/s41586-018-0519-y · Cited by 406 · see citing works

Immunological impact of cell death signaling driven by radiation on the tumor microenvironment

Rodriguez-Ruiz, M. E., Vitale, I., Harrington, K. J., Melero, I., & Galluzzi, L. (2020) · Nature Immunology · doi:10.1038/s41590-019-0561-4 · Cited by 385 · see citing works

Activity of caspase-8 determines plasticity between cell death pathways

Newton, K., Wickliffe, K. E., Maltzman, A., Dugger, D. L., Reja, R., Zhang, Y., Roose‐Girma, M., Modrusan, Z. D., Sagolla, M. S., Webster, J. D., et al. (2019) · Nature · doi:10.1038/s41586-019-1752-8 · Cited by 378 · see citing works

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

Snyder, A. G., Hubbard, N., Messmer, M. N., Kofman, S. B., Hagan, C. E., Orozco, S. L., Chiang, K., Daniels, B. P., Baker, D. A., & Oberst, A. (2019) · Science Immunology · doi:10.1126/sciimmunol.aaw2004 · Cited by 372 · see citing works

MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation

Yoon, S., Kovalenko, A., Bogdanov, K., & Wallach, D. (2017) · Immunity · doi:10.1016/j.immuni.2017.06.001 · Cited by 368 · see citing works

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

Samson, A. L., Zhang, Y., Geoghegan, N. D., Gavin, X. J., Davies, K. A., Mlodzianoski, M. J., Whitehead, L. W., Frank, D. O., Garnish, S. E., Fitzgibbon, C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16887-1 · Cited by 360 · see citing works

Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy

Yamazaki, T., Kirchmair, A., Sato, A., Buqué, A., Rybstein, M., Petroni, G., Bloy, N., Finotello, F., Stafford, L., Navarro Manzano, E., et al. (2020) · Nature Immunology · doi:10.1038/s41590-020-0751-0 · Cited by 359 · see citing works

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

Liu, H., Golji, J., Brodeur, L. K., Chung, F. S., Chen, J. T., deBeaumont, R. S., Bullock, C., Jones, M. D., Kerr, G., Li, L., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0302-5 · Cited by 346 · see citing works

Caspase Substrates and Cellular Remodeling

Crawford, E. D., & Wells, J. A. (2011) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-061809-121639 · Cited by 343 · see citing works

Gut stem cell necroptosis by genome instability triggers bowel inflammation

Wang, R., Li, H., Wu, J., Cai, Z., Li, B., Ni, H., Qiu, X., Chen, H., Liu, W., Yang, Z., et al. (2020) · Nature · doi:10.1038/s41586-020-2127-x · Cited by 310 · see citing works

cGAS-STING–mediated DNA sensing maintains CD8 ⁺ T cell stemness and promotes antitumor T cell therapy

Li, W., Lu, L., Lu, J., Wang, X., Yang, C., Jin, J., Wu, L., Hong, X., Li, F., Cao, D., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay9013 · Cited by 305 · see citing works

RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

Yang, Z., Wang, Y., Zhang, Y., He, X., Zhong, C., Ni, H., Chen, X., Liang, Y., Wu, J., Zhao, S., et al. (2018) · Nature Cell Biology · doi:10.1038/s41556-017-0022-y · Cited by 286 · see citing works

Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

Hou, Y., Liang, H. L., Rao, E., Zheng, W., Huang, X., Deng, L., Zhang, Y., Yu, X., Xu, M. M., Mauceri, H. J., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.07.008 · Cited by 270 · see citing works

Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

Han, C., Liu, Z., Zhang, Y., Shen, A., Dong, C., Zhang, A., Moore, C., Ren, Z., Lu, C., Cao, X., et al. (2020) · Nature Immunology · doi:10.1038/s41590-020-0641-5 · Cited by 153 · see citing works

Type I IFN protects cancer cells from CD8+ T cell–mediated cytotoxicity after radiation

Chen, J., Cao, Y., Markelc, B., Kaeppler, J., Vermeer, J. A. F., & Muschel, R. J. (2019) · Journal of Clinical Investigation · doi:10.1172/jci127458 · Cited by 126 · see citing works

Regulated cell death (RCD) in cancer: key pathways and targeted therapies

Peng, F., Liao, M., Qin, R., Zhu, S., Peng, C. Y., Fu, L., Chen, Y., & Han, B. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01110-y · Cited by 850 · see citing works

Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

Lei, Y., VanPortfliet, J. J., Chen, Y., Bryant, J. D., Li, Y., Fails, D., Torres-Odio, S., Ragan, K. B., Deng, J., Mohan, A., et al. (2023) · Cell · doi:10.1016/j.cell.2023.05.039 · Cited by 292 · see citing works

Harnessing innate immune pathways for therapeutic advancement in cancer

Hu, A.-K., Sun, L., Lin, H., Liao, Y., Yang, H., & Mao, Y. Q. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01765-9 · Cited by 265 · see citing works

Radiation-induced tumor immune microenvironments and potential targets for combination therapy

Guo, S., Yao, Y., Tang, Y., Xin, Z., Wu, D., Ni, C., Huang, J., Wei, Q., & Zhang, T. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01462-z · Cited by 252 · see citing works

A cuproptosis nanocapsule for cancer radiotherapy

Liao, Y., Wang, D., Gu, C., Wang, X., Zhu, S., Zheng, Z., Zhang, F., Yan, J., & Gu, Z. (2024) · Nature Nanotechnology · doi:10.1038/s41565-024-01784-1 · Cited by 170 · see citing works

A human lung alveolus-on-a-chip model of acute radiation-induced lung injury

Dasgupta, Q., Jiang, A. R., Wen, A. M., Mannix, R. J., Man, Y., Hall, S. R. R., Javorsky, E., & Ingber, D. E. (2023) · Nature Communications · doi:10.1038/s41467-023-42171-z · Cited by 145 · see citing works

Cuproptosis, ferroptosis and PANoptosis in tumor immune microenvironment remodeling and immunotherapy: culprits or new hope

Zhang, X., Tang, B., Luo, J., Yang, Y., Weng, Q., Fang, S., Zhao, Z., Tu, J., Chen, M., & Ji, J. (2024) · Molecular Cancer · doi:10.1186/s12943-024-02130-8 · Cited by 147 · see citing works

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Li, J., Zhao, Y., Gong, S., Wang, M., Liu, X., He, Q., Li, Y., Huang, S., Qiao, H., Tan, X.-R., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36523-y · Cited by 143 · see citing works

ADAR1 and ZBP1 in innate immunity, cell death, and disease

Karki, R., & Kanneganti, T. (2023) · Trends in Immunology · doi:10.1016/j.it.2023.01.001 · Cited by 122 · see citing works

Immunogenic PANoptosis‐Initiated Cancer Sono‐Immune Reediting Nanotherapy by Iteratively Boosting Cancer Immunity Cycle

Zhou, L., Lyu, J., Liu, F., Su, Y., Feng, L., & Zhang, X. (2023) · Advanced Materials · doi:10.1002/adma.202305361 · Cited by 114 · see citing works

ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity

Yu, H., Yang, B., Yang, J., Shi, X., Yang, X., Zhang, D., Zhao, D., Yan, W., Chen, L., Zheng, H., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810224 · Cited by 105 · see citing works

Radiotherapy modulates tumor cell fate decisions: a review

Chen, H., Han, Z., Luo, Q., Wang, Y., Li, Q., Zhou, L., & Zuo, H.-D. (2022) · Radiation Oncology · doi:10.1186/s13014-022-02171-7 · Cited by 95 · see citing works

Targeting regulated cell death: Apoptosis, necroptosis, pyroptosis, ferroptosis, and cuproptosis in anticancer immunity

Guo, Z., Liu, Y., Chen, D., Sun, Y., Li, D., Meng, Y., Zhou, Q., Zeng, F., Deng, G., & Chen, X. (2025) · Journal of Translational Internal Medicine · doi:10.1515/jtim-2025-0004 · Cited by 99 · see citing works

Regulated cell death in cancer: from pathogenesis to treatment

Gong, L., Huang, D., Shi, Y., Liang, Z., & Bu, H. (2022) · Chinese Medical Journal · doi:10.1097/cm9.0000000000002239 · Cited by 94 · see citing works

The Z-nucleic acid sensor ZBP1 in health and disease

Maelfait, J., & Rehwinkel, J. (2023) · The Journal of Experimental Medicine · doi:10.1084/jem.20221156 · Cited by 91 · see citing works

A Single‐Atom Manganese Nanozyme Mn‐N/C Promotes Anti‐Tumor Immune Response via Eliciting Type I Interferon Signaling

Qiao, W., Chen, J., Zhou, H., Hu, C., Dalangood, S., Li, H., Yang, D., Yang, Y. P., & Gui, J. (2024) · Advanced Science · doi:10.1002/advs.202305979 · Cited by 84 · see citing works

STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

Lu, L., Yang, C., Zhou, X., Wu, L., Hong, X., Li, W., Wang, X., Yang, Y., Cao, D., Zhang, A., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113108 · Cited by 74 · see citing works

Enhancing radiotherapy-induced anti-tumor immunity via nanoparticle-mediated STING agonist synergy

Zeng, Q., Liu, M., Wang, Z., Zhou, R., & Ai, K. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02366-y · Cited by 81 · see citing works

Pivotal roles of tumor‐draining lymph nodes in the abscopal effects from combined immunotherapy and radiotherapy

Liu, Z., Yu, Z., Chen, D., Verma, V., Yuan, C., Wang, M., Wang, F., Fan, Q., Wang, X., Li, Y., et al. (2022) · 癌症：英文版 · doi:10.1002/cac2.12348 · Cited by 69 · see citing works

Triggering endogenous Z-RNA sensing for anti-tumor therapy through ZBP1-dependent necroptosis

Yang, T., Wang, G., Zhang, M., Hu, X., Li, Q., Yun, F., Xing, Y., Song, X., Zhang, H., Hu, G., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113377 · Cited by 64 · see citing works

Z-DNA binding protein 1 orchestrates innate immunity and inflammatory cell death

Song, Q., Fan, Y., Zhang, H., & Wang, N. (2024) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2024.03.005 · Cited by 67 · see citing works

Identification of Necroptosis and Immune Infiltration in Heart Failure Through Bioinformatics Analysis

Zhu, Y., Zhang, Q., Wang, Y., Liu, W., Zeng, S., Yuan, Q., & Zhang, K. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s502203 · Cited by 68 · see citing works

cGAS‐STING signaling in cell death: Mechanisms of action and implications in pathologies

Xu, Y., Chen, C., Liao, Z., & Xu, P. (2023) · European Journal of Immunology · doi:10.1002/eji.202350386 · Cited by 62 · see citing works

Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming

Yu, T., Liu, Z., Tao, Q., Xu, X., Li, X., Li, Y., Chen, M., Liu, R., Chen, D., Wu, M., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216824 · Cited by 63 · see citing works

Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis

Liu, H., Liu, Y., Fan, W., & Fan, B. (2022) · Cell Communication and Signaling · doi:10.1186/s12964-022-01005-z · Cited by 59 · see citing works

When DNA-damage responses meet innate and adaptive immunity

Tong, J., Song, J., Zhang, W., Zhai, J., Guan, Q., Wang, H., Liu, G., & Zheng, C. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05214-2 · Cited by 63 · see citing works

ZBP1-Mediated Necroptosis: Mechanisms and Therapeutic Implications

Chen, X., Dai, Y., Wan, X.-X., Hu, X., Zhao, W., Ban, X.-X., Wan, H., Huang, K., Zhāng, Q., & Xiong, K. (2022) · Molecules · doi:10.3390/molecules28010052 · Cited by 59 · see citing works

The paradoxical role of radiation‐induced cGAS–STING signalling network in tumour immunity

Zhang, X., Zhang, H., Zhang, J., Yang, M., Zhu, M., Yin, Y., Fan, X., & Yu, F. (2022) · Immunology · doi:10.1111/imm.13592 · Cited by 57 · see citing works

Necroptosis-dependent Immunogenicity of Cisplatin: Implications for Enhancing the Radiation-induced Abscopal Effect

Luo, R., Onyshchenko, K., Wang, L., Gaedicke, S., Grosu, A., Firat, E., & Niedermann, G. (2022) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-1591 · Cited by 57 · see citing works

Olaparib enhances radiation-induced systemic anti-tumor effects via activating STING-chemokine signaling in hepatocellular carcinoma

Chen, G., Zheng, D.-X., Zhou, Y., Du, S., & Zeng, Z. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216507 · Cited by 57 · see citing works

PANoptosis in cancer: bridging molecular mechanisms to therapeutic innovations

Lin, J., Wang, T., Huang, R., Tan, Y., Chen, D., & Ju, H. (2025) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01329-z · Cited by 62 · see citing works

Deciphering the Biological Effects of Radiotherapy in Cancer Cells

Zhou, L., Zheng, X., Ding, C., Zou, Z., Liang, Y., Zhou, Y., & Li, X. (2022) · Biomolecules · doi:10.3390/biom12091167 · Cited by 55 · see citing works

Ferroptosis, necroptosis, and pyroptosis in cancer: Crucial cell death types in radiotherapy and post-radiotherapy immune activation

Wang, Y., Wang, Y., Pan, J., Gan, L., & Xue, J. (2023) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2023.109689 · Cited by 53 · see citing works

How Chemotherapy Affects the Tumor Immune Microenvironment: A Narrative Review

Merlano, M. C., Denaro, N., Galizia, D., Ruatta, F., Occelli, M., Minei, S., Abbona, A., Paccagnella, M., Ghidini, M., & Garrone, O. (2022) · Biomedicines · doi:10.3390/biomedicines10081822 · Cited by 48 · see citing works

MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10

Peng, C., Tu, G., Wang, J., Wang, Y., Wu, P., Yu, L. J., Li, Z., & Yu, X. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05655-w · Cited by 46 · see citing works

Radiation combined with immune checkpoint inhibitors for unresectable locally advanced non-small cell lung cancer: synergistic mechanisms, current state, challenges, and orientations

Wu, L., Zhang, Z., Bai, M., Yan, Y., Yu, J., & Xu, Y. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01139-8 · Cited by 48 · see citing works

Pyroptotic cell death: an emerging therapeutic opportunity for radiotherapy

Li, H., Yang, T., Zhang, J., Xue, K., Ma, X., Yu, B., & Jin, X. (2024) · Cell Death Discovery · doi:10.1038/s41420-024-01802-0 · Cited by 45 · see citing works

Role of autophagy in tumor response to radiation: Implications for improving radiotherapy

Roy, A., Bera, S., Saso, L., & Dwarakanath, B. S. R. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.957373 · Cited by 43 · see citing works

In Situ STING‐Activating Nanovaccination with TIGIT Blockade for Enhanced Immunotherapy of Anti‐PD‐1‐Resistant Tumors

Zhang, B., Zhang, J., Li, Y., Li, N., Wang, Y., Jang, R., Xu, X., Li, R., Chen, Z., Duan, S., et al. (2023) · Advanced Materials · doi:10.1002/adma.202300171 · Cited by 43 · see citing works

Adding liposomal doxorubicin enhances the abscopal effect induced by radiation/αPD1 therapy depending on tumor cell mitochondrial DNA and cGAS/STING

Wang, L., Luo, R., Onyshchenko, K., Rao, X., Wang, M., Menz, B., Gaedicke, S., Grosu, A., Firat, E., & Niedermann, G. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-006235 · Cited by 43 · see citing works

Necroptosis stimulates interferon-mediated protective anti-tumor immunity

Rucker, A. J., Park, C., Li, Q.-J., Moseman, E. A., & Chan, F. K.-M. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06801-8 · Cited by 38 · see citing works

The crosstalk between DNA-damage responses and innate immunity

He, M., Jiang, H., Li, S., Xue, M., Wang, H., Zheng, C., & Tong, J. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112768 · Cited by 38 · see citing works

Strategies involving STING pathway activation for cancer immunotherapy: Mechanism and agonists

Pan, X., Zhang, W., Guo, H., Wang, L., Wu, H., Ding, L., & Yang, B. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115596 · Cited by 35 · see citing works

High-LET charged particles: radiobiology and application for new approaches in radiotherapy

Helm, A., & Fournier, C. (2023) · Strahlentherapie und Onkologie · doi:10.1007/s00066-023-02158-7 · Cited by 35 · see citing works

Single-Cell Transcriptome Analysis of Radiation Pneumonitis Mice

Yang, M., Fan, Q., Hei, T. K., Chen, G., Cao, W., Meng, G., & Han, W. (2022) · Antioxidants · doi:10.3390/antiox11081457 · Cited by 34 · see citing works

Noncanonical MAVS signaling restrains dendritic cell–driven antitumor immunity by inhibiting IL-12

Wu, L., Hong, X., Yang, C. X., Yang, Y., Li, W., Lu, L., Cai, M., Cao, D., Zhuang, G., & Deng, L. (2023) · Science Immunology · doi:10.1126/sciimmunol.adf4919 · Cited by 34 · see citing works

DNA‐Capturing Manganese‐Coordinated Chitosan Microparticles Potentiate Radiotherapy via Activating the cGAS‐STING Pathway and Maintaining Tumor‐Infiltrating CD8 + T‐Cell Stemness

Zhang, S., Wang, C., Zhu, Y., Gao, J., Yan, Y., Chen, M., Yan, X., Liu, Z., & Feng, L. (2025) · Advanced Materials · doi:10.1002/adma.202418583 · Cited by 35 · see citing works

Inhibition of tumor intrinsic BANF1 activates antitumor immune responses via cGAS-STING and enhances the efficacy of PD-1 blockade

Wang, M., Huang, Y., Chen, M., Wang, W., Wu, F., Zhong, T., Chen, X., Wang, F., Li, Y., Yu, J., et al. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2023-007035 · Cited by 32 · see citing works

STING Agonist‐Loaded Nanoparticles Promotes Positive Regulation of Type I Interferon‐Dependent Radioimmunotherapy in Rectal Cancer

Wang, L., Zhou, H., Chen, Q., Lin, Z., Jiang, C., Chen, X., Chen, M., Liu, L., Shao, L., Liu, X., et al. (2023) · Advanced Science · doi:10.1002/advs.202307858 · Cited by 31 · see citing works

Cell death in cancer

Conrad, M., Strasser, A., Jost, P. J., Yuan, J., Shao, F., Vandenabeele, P., & Wahida, A. (2026) · Cell · doi:10.1016/j.cell.2026.03.024 · Cited by 36 · see citing works

Z‐ Nucleic Acid Sensing and Activation of ZBP1 in Cellular Physiology and Disease Pathogenesis

Mishra, S., Dey, A. A., & Kesavardhana, S. (2025) · Immunological Reviews · doi:10.1111/imr.13437 · Cited by 29 · see citing works

A Polymeric mRNA Vaccine Featuring Enhanced Site‐Specific mRNA Delivery and Inherent STING‐Stimulating Performance for Tumor Immunotherapy

Guo, X., Yang, Z., Guo, Z., Lai, H., Meng, H., Meng, M., Li, T., Li, Z., Chen, J., Feng, Y., et al. (2025) · Advanced Materials · doi:10.1002/adma.202410998 · Cited by 29 · see citing works

Cancer cell-specific cGAS/STING Signaling pathway in the era of advancing cancer cell biology

Kumar, V., Bauer, C., & Stewart, J. H. (2023) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2023.151338 · Cited by 30 · see citing works

Lovastatin/SN38 co-loaded liposomes amplified ICB therapeutic effect via remodeling the immunologically-cold colon tumor and synergized stimulation of cGAS-STING pathway

Yang, Y. A., Qi, J., Hu, J., Zhou, Y., Zheng, J., Deng, W., Inam, M., Guo, J., Xie, Y., Li, Y., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216765 · Cited by 28 · see citing works

Ionizing Radiation Drives Key Regulators of Antigen Presentation and a Global Expansion of the Immunopeptidome

Tailor, A., Estéphan, H., Parker, R., Woodhouse, I. B., Abdulghani, M., Nicastri, A., Jones, K. I., Salatino, S., Muschel, R. J., Humphrey, T. C., et al. (2022) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2022.100410 · Cited by 27 · see citing works

At the Crossroads of the cGAS-cGAMP-STING Pathway and the DNA Damage Response: Implications for Cancer Progression and Treatment

Korneenko, T. V., Pestov, N. B., Nevzorov, I. A., Daks, A. A., Николаевич, Т. К., Солопова, О. Н., & Barlev, N. A. (2023) · Pharmaceuticals · doi:10.3390/ph16121675 · Cited by 28 · see citing works

Oxygen self-supplying nanoradiosensitizer activates cGAS-STING pathway to enhance radioimmunotherapy of triple negative breast cancer

Wang, X., Yang, Y., Wang, P., Li, Q., Gao, W., Sun, Y., Tian, G., Zhang, G., & Xiao, J. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.049 · Cited by 26 · see citing works

DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling

Wheeler, O. P. G., & Unterholzner, L. (2023) · Essays in Biochemistry · doi:10.1042/ebc20220241 · Cited by 26 · see citing works

FePd Nanozyme- and SKN-Encapsulated Functional Lipid Nanoparticles for Cancer Nanotherapy via ROS-Boosting Necroptosis

Xie, W., Li, Y., Guo, Z., Lu, J., Li, G., Zhang, Z., Zhang, F., Wei, Y., Wang, X., & Zhao, L. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c18497 · Cited by 25 · see citing works

Dendritic cells instruct T cell anti-tumor immunity and immunotherapy response

Xiao, Z., Wang, J., Yang, J., Guo, F., Zhang, L., & Zhang, L. (2025) · The Innovation Medicine · doi:10.59717/j.xinn-med.2025.100128 · Cited by 26 · see citing works

Mitochondrial DNA on Tumor-Associated Macrophages Polarization and Immunity

Guo, Y., Tsai, H., Zhang, L., & Zhu, H. (2022) · Cancers · doi:10.3390/cancers14061452 · Cited by 26 · see citing works

PANoptosis-related prognostic signature predicts overall survival of cutaneous melanoma and provides insights into immune infiltration landscape

Wang, W., Zhou, Q., Lan, L., & Xu, X. (2023) · Scientific Reports · doi:10.1038/s41598-023-35462-4 · Cited by 25 · see citing works

The multiple faces of cGAS-STING in antitumor immunity: prospects and challenges

Zhou, Z., Huang, S., Fan, F., Xu, Y., Moore, C., Li, S., & Han, C. (2024) · Medical Review · doi:10.1515/mr-2023-0061 · Cited by 25 · see citing works

Experimental Type 2 diabetes and lipotoxicity-associated neuroinflammation involve mitochondrial DNA-mediated cGAS/STING axis: implication of Type-1 interferon response in cognitive impairment

Kumari, P., Sood, A., Fernandes, V., Khan, I., Khatri, D. K., & Singh, S. B. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-03933-y · Cited by 24 · see citing works

NR4A1 depletion inhibits colorectal cancer progression by promoting necroptosis via the RIG-I-like receptor pathway

Zhu, J., Li, J., Yang, K., Chen, Y., Wang, J., Shen, K., Shen, K., Wang, K., Shi, T., & Chen, W. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216693 · Cited by 23 · see citing works

Flotillin-1 enhances radioresistance through reducing radiation-induced DNA damage and promoting immune escape via STING signaling pathway in non-small cell lung cancer

Wang, Y., Meng, L., Meng, S., Huang, L., Luo, S., Wu, X., & Gong, X. (2023) · Cancer Biology & Therapy · doi:10.1080/15384047.2023.2203332 · Cited by 23 · see citing works

In situ vaccination caused by diverse irradiation-driven cell death programs

Wang, Y., Li, Y., Yang, Y., Swift, M. L., Zhang, Z., Wu, S., Sun, Y., & Yang, K. (2024) · Theranostics · doi:10.7150/thno.86004 · Cited by 22 · see citing works

Programmed cell death in triple-negative breast cancer

Liu, Y., He, J., Chen, J., Chen, T., Li, W., Yang, Z., & Zeng, F. (2025) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-025-00789-5 · Cited by 22 · see citing works

Targeting STING signaling for the optimal cancer immunotherapy

Xu, Y., & Xiong, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1482738 · Cited by 22 · see citing works

Cyclic GMP-AMP synthase recognizes the physical features of DNA

Dong, L., Hou, Y.-R., Xu, N., Gao, X., Sun, Z., Yang, Q., & Wang, L. (2024) · Acta Pharmacologica Sinica · doi:10.1038/s41401-024-01369-7 · Cited by 21 · see citing works

Validation of CD98hc as a Therapeutic Target for a Combination of Radiation and Immunotherapies in Head and Neck Squamous Cell Carcinoma

Köseer, A. S., Loureiro, L. R., Jureczek, J., Mitwasi, N., Soto, K. E. G., Aepler, J., Bartsch, T., Feldmann, A., Kunz‐Schughart, L. A., Linge, A., et al. (2022) · Cancers · doi:10.3390/cancers14071677 · Cited by 20 · see citing works

Biomaterial-enabled therapeutic modulation of cGAS-STING signaling for enhancing antitumor immunity

Liu, Y., Yang, F., Wang, X., Yang, B., Li, M., & Luo, Z. Y. (2023) · Molecular Therapy · doi:10.1016/j.ymthe.2023.03.026 · Cited by 23 · see citing works

The role of cGAS-STING in remodeling the tumor immune microenvironment induced by radiotherapy

Jiang, Q., Chen, Z., Jiang, J., Chen, Q., Lan, H., Zhu, J. Y., & Mao, W. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.104658 · Cited by 20 · see citing works

Loss of RPA1 Impairs Peripheral T Cell Homeostasis and Exacerbates Inflammatory Damage through Triggering T Cell Necroptosis

Song, J., Zhang, X., Yin, Y., Guo, M., Zhao, X., Wang, L., Ren, C., Yin, Y., Zhang, X., Deng, X., et al. (2023) · Advanced Science · doi:10.1002/advs.202206344 · Cited by 20 · see citing works

FOSL2 promotes intertumoral infiltration of T cells and increases pathological complete response rates in locally advanced rectal cancer patients

Xu, K., Yin, X., Zhou, B., Zheng, X., Wang, H., Chen, J., Cai, X., Gao, H., Xu, X., Wang, L., et al. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216145 · Cited by 19 · see citing works

LILRB2 inhibition enhances radiation sensitivity in non-small cell lung cancer by attenuating radiation-induced senescence

Chen, X., Yuan, M., Zhong, T., Wang, M., Wu, F., Lu, J., Sun, D., Xiao, C., Sun, Y., Hu, Y., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216930 · Cited by 19 · see citing works

A self‐assembled, genetically engineered, irradiated tumor cell debris vaccine

Sun, Y., Hu, Y., Geng, Y., Wan, C., Liu, Y., Liao, Y., Shi, X., Lovell, J. F., Yang, K., & Jin, H. (2024) · Exploration · doi:10.1002/exp.20220170 · Cited by 18 · see citing works

Loss of Nrf2 aggravates ionizing radiation-induced intestinal injury by activating the cGAS/STING pathway via Pirin

Xu, Y., Wang, L., Liao, H. H., Li, X., Zhang, Y., Chen, X., Xu, B., Liu, Y., Tu, W., & Liu, Y. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.217218 · Cited by 18 · see citing works

Radiotherapy enhances anticancer CD8 T cell responses by cGAMP transfer through LRRC8A/C volume-regulated anion channels

Cao, L., Li, W., Li, Z., Wei, X., Ding, J., Zhou, C., Chen, X., Huang, Z., Shao, Z., Shen, J., et al. (2025) · Science Immunology · doi:10.1126/sciimmunol.adn1630 · Cited by 17 · see citing works

ZBP1 and heatstroke

Li, F., Deng, J., He, Q., & Zhong, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1091766 · Cited by 17 · see citing works

The role of DNA in the pathogenesis of SLE: DNA as a molecular chameleon

Pisetsky, D. S., & Herbert, A. G. (2024) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2023-225266 · Cited by 17 · see citing works

ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

Wang, Q., Wu, Z., Yang, Y., Yang, C., Deng, H., Zhou, X., Xu, S., Wu, L., Hong, X., Yu, X., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116314 · Cited by 16 · see citing works

Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity

Qiao, W., Hu, C., Ma, J., Dong, X., Dalangood, S., Li, H., Yuan, C., Lu, B., Gao, W., Wen, Z., et al. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216370 · Cited by 16 · see citing works

Loss of the DNA repair protein, polynucleotide kinase/phosphatase, activates the type 1 interferon response independent of ionizing radiation

Kate, W. D., Fanta, M., & Weinfeld, M. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae654 · Cited by 17 · see citing works

The Role of Post-Translational Modifications in Necroptosis

Xiao, H., Han, Z., Xu, M., Gao, X., Qiu, S., Ren, N., Yi, Y., & Zhou, C. (2025) · Biomolecules · doi:10.3390/biom15040549 · Cited by 15 · see citing works

Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

Miao, N., Cao, D., Jin, J., Ma, G., Yu, H., Qu, J., Li, G., Gao, C., Dong, D., Xia, F., et al. (2024) · The Journal of Experimental Medicine · doi:10.1084/jem.20231486 · Cited by 15 · see citing works

Manganese boosts natural killer cell function via cGAS–STING mediated UTX expression

Ming, Q., Liu, J., Lv, Z., Wang, T., Fan, R., Zhang, Y., Chen, M., Sun, Y., Han, W., & Mei, Q. (2024) · MedComm · doi:10.1002/mco2.683 · Cited by 15 · see citing works

Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation

Alshebremi, M., Tomchuck, S. L., Myers, J. T., Kingsley, D. T., Eid, S., Abiff, M., Bonner, M., Saab, S. T., Choi, S. H., & Huang, A. Y.-C. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-006608 · Cited by 14 · see citing works

Zbp1 gene: a modulator of multiple aging hallmarks as potential therapeutic target for age-related diseases

Radak, M., & Fallahi, H. (2023) · Biogerontology · doi:10.1007/s10522-023-10039-w · Cited by 15 · see citing works

Zα domain proteins mediate the immune response

Zhong, Y., Zhong, X., Qiao, L., Wu, H., Liu, C., & Zhang, T. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1241694 · Cited by 14 · see citing works

Are charged particles a good match for combination with immunotherapy? Current knowledge and perspectives

Helm, A., Totis, C., Durante, M., & Fournier, C. (2023) · International review of cytology · doi:10.1016/bs.ircmb.2023.01.001 · Cited by 13 · see citing works

Pan-cancer analysis identifies protein arginine methyltransferases PRMT1 and PRMT5 and their related signatures as markers associated with prognosis, immune profile, and therapeutic response in lung adenocarcinoma

Wang, J., Wu, M., Sun, J., Chen, M., Zhang, Z., Yu, J., & Chen, D. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e22088 · Cited by 13 · see citing works

Targeting programmed cell death pathways in gastric cancer: a focus on pyroptosis, apoptosis, necroptosis and PANoptosis

Yao, M., Miao, L., Wang, X., & Han, Y. (2025) · Gene · doi:10.1016/j.gene.2025.149546 · Cited by 12 · see citing works

STING pathway as a cancer immunotherapy: Progress and challenges in activating anti-tumor immunity

Tabar, M. M. M., Fathi, M., Kazemi, F., Bazregari, G., & Ghasemian, A. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09418-4 · Cited by 12 · see citing works

Sonrotoclax (BGB-11417) synergistically amplifies the radiotherapy-elicited anti-tumor immune response

Ma, M., Zhang, Z., Tian, C., Liu, X., Wu, M., Yu, J., Yuan, J., & Chen, D. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217759 · Cited by 12 · see citing works

Taohong siwu decoction attenuates AIM2 and NLRC4 inflammasomes by ameliorates deoxyribonucleic acid damage after ischemic stroke

Wang, N., Chu, F., Zhang, L., Fei, C., Yu, C., Xue, S., Wang, Y., Fang, L., Peng, D., Duan, X., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.954867 · Cited by 12 · see citing works

Nucleic Acid Sensor-Mediated PANoptosis in Viral Infection

Zhu, L., Qi, Z., Zhang, H., & Wang, N. (2024) · Viruses · doi:10.3390/v16060966 · Cited by 12 · see citing works

Review of Excessive Cytosolic DNA and Its Role in AIM2 and cGAS-STING Mediated Psoriasis Development

Xu, T., Zhong, X., Luo, N., Ma, W., & Hao, P. (2024) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s476785 · Cited by 11 · see citing works

Identification and Validation of the lncRNA MYOSLID as a Regulating Factor of Necroptosis and Immune Cell Infiltration in Colorectal Cancer following Necroptosis-Related LncRNA Model Establishment

Wu, Z., Zhang, F., Wang, Y., Lu, Z., & Lin, C. (2022) · Cancers · doi:10.3390/cancers14184364 · Cited by 11 · see citing works

Design and bioactivity of Eudragit® encapsulated pH-Sensitive enteric/gastric soluble fluorescent agent

Lian, G., Hu, K., Zhou, M. R., Liu, Y., & Jin, G. (2023) · Journal of Polymer Research · doi:10.1007/s10965-023-03487-y · Cited by 11 · see citing works

ZBP1-mediated sensing of genomic stress in cancer therapy

Zhong, X., Balachandran, S., & Zhang, T. (2026) · Ferroptosis and Oxidative Stress · doi:10.70401/fos.2026.0035

Abstract SY39-03: Radiation-mediated DNA sensing pathway for immunity and tumor regression

Fu, Y. (2015) · Cancer Research · doi:10.1158/1538-7445.am2015-sy39-03

ZBP1 links infections to cancer immunotherapy

Galluzzi, L., Brackett, S., & Johnson, N. (2025) · Cell Research · doi:10.1038/s41422-025-01196-3 · Cited by 1 · see citing works

Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway

Wang, Y., Zhao, M., He, S., Luo, Y., Zhao, Y., Cheng, J. Q., Gong, Y., Xie, J., Wang, Y., Hu, B., et al. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1423-5 · Cited by 96 · see citing works

The Impact of Radiation-Induced DNA Damage on cGAS-STING-Mediated Immune Responses to Cancer

Storozynsky, Q. T., & Hitt, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228877 · Cited by 233 · see citing works