Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct Mechanisms

Cited by (257)

Items 101–200 of 257

  1. Disruption of Mechanisms That Prevent Rereplication Triggers a DNA Damage Response
    Vincent Archambault, Amy E. Ikui, Benjamin Jacob Drapkin, Frederick R. Cross · 2005 · Molecular and Cellular Biology
  2. The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase in long patch base excision repair
    Gembka, A., Toueille, M., Smirnova, E., Poltz, R., Ferrari, E., Villani, G., Hubscher, U. · 2007 · Nucleic Acids Research
  3. ATR signaling at a glance
    Bunsyo Shiotani, Lee Zou · 2009 · Journal of Cell Science
  4. The Checkpoint Protein Rad24 of Saccharomyces cerevisiae Is Involved in Processing Double-Strand Break Ends and in Recombination Partner Choice
    Yael Aylon, Martin Kupiec · 2003 · Molecular and Cellular Biology
  5. The S-phase checkpoint and its regulation in Saccharomyces cerevisiae
    Maria Pia Longhese, Michela Clerici, Giovanna Lucchini · 2003 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  6. hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation.
    Deborah A. Greer, Blair D.A. Besley, Katherine B Kennedy, Scott K. Davey · 2003 · PubMed
  7. Hiding at the ends of yeast chromosomes: Telomeres, nucleases and checkpoint pathways
    Lydall, David · 2003 · Journal of Cell Science
  8. Disruption of the Rad9/Rad1/Hus1 (9–1–1) complex leads to checkpoint signaling and replication defects
    Shilai Bao, Tao Lu, Xin A. Wang, Huyong Zheng, Li‐E Wang, Qingyi Wei, Walter N. Hittelman, Lei Li · 2004 · Oncogene
  9. Expanded CAG Repeats Activate the DNA Damage Checkpoint Pathway
    Mayurika Lahiri, T. L. Gustafson, Elizabeth R Majors, Catherine H. Freudenreich · 2004 · Molecular Cell
  10. Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences
    Jiang, Guochun, Sancar, Aziz · 2006 · Molecular and Cellular Biology
  11. Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage
    Ishan Deshpande, Andrew Seeber, Kenji Shimada, Jeremy J. Keusch, H. Gut, Susan M. Gasser · 2017 · Molecular Cell
  12. Mec1 and Rad53 Inhibit Formation of Single-Stranded DNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants
    Xindan Jia, Ted A. Weinert, David A. Lydall · 2004 · Genetics
  13. Mechanisms of Checkpoint Kinase Rad53 Inactivation after a Double-Strand Break in Saccharomyces cerevisiae
    Ghislaine Guillemain, Émilie Ma, Sarah Mauger, Simona M. Miron, Robert Thaï, Raphaël Guérois, Françoise Ochsenbein, Marie‐Claude Marsolier‐Kergoat · 2007 · Molecular and Cellular Biology
  14. Genomic instability and endoreduplication triggered by RAD17 deletion
    Xin Wang, Lee Zou, Huyong Zheng, Qingyi Wei, Stephen Joseph Elledge, Lei Li · 2003 · Genes & Development
  15. A domain of Rad9 specifically required for activation of Chk1 in budding yeast
    Blankley, Richard T., Lydall, David · 2004 · Journal of Cell Science
  16. The S phase checkpoint: When the crowd meets at the fork
    Vanesa Gottifredi, Carol L. Prives · 2005 · Seminars in Cell and Developmental Biology
  17. Dif1 Controls Subcellular Localization of Ribonucleotide Reductase by Mediating Nuclear Import of the R2 Subunit
    Xiaorong Wu, Mingxia Huang · 2008 · Molecular and Cellular Biology
  18. The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast
    Karine Dubrana, Haico van Attikum, Florence Hediger, Susan M. Gasser · 2007 · Journal of Cell Science
  19. DNA damage-induced gene expression inSaccharomyces cerevisiae
    Yu Vincent Fu, Landon Pastushok, Wei Xiao · 2008 · FEMS Microbiology Reviews
  20. Lagging Strand Replication Proteins in Genome Stability and DNA Repair
    Marie L. Rossi, Vandana Purohit, Patrick D. Brandt, Robert A. Bambara · 2005 · Chemical Reviews
  21. A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint
    Eun-Jin Erica Hong, G. Shirleen Roeder · 2002 · Genes & Development
  22. Loss of Sin3/Rpd3 Histone Deacetylase Restores the DNA Damage Response in Checkpoint-Deficient Strains of Saccharomyces cerevisiae
    Kenneth L. Scott, Sharon E. Plon · 2003 · Molecular and Cellular Biology
  23. Checkpoint responses to replication stalling: inducing tolerance and preventing mutagenesis
    Mihoko Kai, Teresa S.‐F. Wang · 2003 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  24. Loss of Rereplication Control inSaccharomyces cerevisiaeResults in Extensive DNA Damage
    Brian M. Green, Joachim J. Li · 2004 · Molecular Biology of the Cell
  25. The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment
    Daisuke Nakada · 2003 · Nucleic Acids Research
  26. Yeast Rad52 and Rad51 Recombination Proteins Define a Second Pathway of DNA Damage Assessment in Response to a Single Double-Strand Break
    Sang Eun Lee, Achille Pellicioli, Moreshwar B. Vaze, Neal Sugawara, Anna Malkova, Marco Foiani, James E. Haber · 2003 · Molecular and Cellular Biology
  27. DNA Damage Regulates Chk2 Association with Chromatin
    Jia Li, David F. Stern · 2005 · Journal of Biological Chemistry
  28. CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation
    Genevieve M. Vidanes, Frédéric D. Sweeney, Sarah Galicia, Stephanie K. Cheung, John P. Doyle, Daniel Durocher, David Paul Toczyski · 2010 · PLoS Biology
  29. A Role of the C-terminal Region of Human Rad9 (hRad9) in Nuclear Transport of the hRad9 Checkpoint Complex
    Itaru Hirai, Hong‐Gang Wang · 2002 · Journal of Biological Chemistry
  30. Cell Cycle Checkpoint Control Mechanisms That Can Be Disrupted in Cancer
    Bipin C. Dash, Wafik S. El‐Deiry · 2004 · Humana Press eBooks
  31. The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
    Hien-Ping Ngo, David A. Lydall · 2015 · Nucleic Acids Research
  32. Association of Rad9 with Double-Strand Breaks through a Mec1-Dependent Mechanism
    Takahiro Naiki, Tatsushi Wakayama, Daisuke Nakada, Kunihiro Matsumoto, Katsunori Sugimoto · 2004 · Molecular and Cellular Biology
  33. Molecular Anatomy of the DNA Damage and Replication Checkpoints
    Jun Qin, Lei Li · 2003 · Radiation Research
  34. Role of the C Terminus of Mec1 Checkpoint Kinase in Its Localization to Sites of DNA Damage
    Daisuke Nakada, Yukinori Hirano, Yuya Tanaka, Katsunori Sugimoto · 2005 · Molecular Biology of the Cell
  35. Ccr4-Not Complex mRNA Deadenylase Activity Contributes to DNA Damage Responses in Saccharomyces cerevisiae
    Ana Traven, Andrew Hammet, Nora Tenis, Clyde L. Denis, Jörg Heierhorst · 2004 · Genetics
  36. Activation of the Checkpoint Kinase Rad53 by the Phosphatidyl Inositol Kinase-like Kinase Mec1
    Nianhan Jia-Lin Ma, Soo-Jung Lee, Jimmy Duong, David F. Stern · 2005 · Journal of Biological Chemistry
  37. Replication, Recombination, and Repair
    Hannah L. Klein, Kenneth N. Kreuzer · 2002 · Molecular Cell
  38. Elevated Levels of the Polo Kinase Cdc5 Override the Mec1/ATR Checkpoint in Budding Yeast by Acting at Different Steps of the Signaling Pathway
    Roberto Antonio Donnianni, Matteo Ferrari, Federico Lazzaro, Michela Clerici, Benjamin Tamilselvan Nachimuthu, Paolo Plevani, Marco Muzi-Falconi, Achille Pellicioli · 2010 · PLoS Genetics
  39. Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae
    Julia C. Mallory, Vladimir I. Bashkirov, Kelly M. Trujillo, Jachen A. Solinger, Margaret Dominska, Patrick Sung, Wolf‐Dietrich Heyer, Thomas D. Petes · 2003 · DNA repair
  40. The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage
    Farokh Dotiwala, Julian Haase, Ayelet Arbel‐Eden, Kerry Bloom, James E. Haber · 2007 · Proceedings of the National Academy of Sciences
  41. S-Phase Checkpoint Pathways Stimulate the Mobility of the Retrovirus-Like Transposon Ty1
    M. Joan Curcio, Alison E. Kenny, Sharon P. Moore, David J Garfinkel, M Weintraub, Eric Gamache, Derek T. Scholes · 2007 · Molecular and Cellular Biology
  42. The DNA damage checkpoint: A tale from budding yeast
    Paolo Pizzul, Erika Casari, Marco Gnugnoli, Carlo Rinaldi, Flavio Corallo, Maria Pia Longhese · 2022 · Frontiers in Genetics
  43. Critical role for chicken Rad17 and Rad9 in the cellular response to DNA damage and stalled DNA replication
    Masahiko Kobayashi, Atsushi Hirano, Tomoyasu Kumano, Shuanglin Xiang, Keiko L. Mihara, Yasunari Haseda, Osamu Matsui, Hiroko Shimizu, Kenichi Yamamoto · 2004 · Genes to Cells
  44. DNA Damage Checkpoints Are Involved in Postreplication Repair
    Leslie Barbour, Lindsay G. Ball, Ke Zhang, Wei Xiao · 2006 · Genetics
  45. The Ddc2/ATRIP checkpoint protein monitors meiotic recombination intermediates
    Esther Refolio, Santiago Canut Cavero, Edyta Marcon, Raimundo Freire, Pedro A. San-Segundo · 2011 · Journal of Cell Science
  46. A Tel1/MRX-Dependent Checkpoint Inhibits the Metaphase-to-Anaphase Transition after UV Irradiation in the Absence of Mec1
    Michela Clerici, Veronica Baldo, Davide Mantiero, Francisca Lottersberger, Giovanna Lucchini, Maria Pia Longhese · 2004 · Molecular and Cellular Biology
  47. Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast
    Livia Pérez-Hidalgo, Sergio Moreno, Pedro A. San-Segundo · 2002 · Journal of Cell Science
  48. Induction/reversal of drug resistance in gastric cancer by non-coding RNAs (Review)
    Chao Chen, Xiaohuan Tang, Yuanda Liu, Jiaming Zhu, Jingjing Liu · 2019 · International Journal of Oncology
  49. G1 and S-Phase Checkpoints, Chromosome Instability, and Cancer
    Hiroshi Nojima · 2004 · Humana Press eBooks
  50. ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage
    Annette L. Medhurst, Daniël O. Warmerdam, İldem Akerman, Edward H. Verwayen, Roland Kanaar, Veronique A. J. Smits, Nick D. Lakin · 2008 · Journal of Cell Science
  51. Response to DNA damage: why do we need to focus on protein phosphatases?
    Midori Shimada, Makoto Nakanishi · 2013 · Frontiers in Oncology
  52. Recruitment of ATR‐ATRIP, Rad17, and 9‐1‐1 Complexes to DNA Damage
    Xiaohong Helena Yang, Lee Zou · 2006 · Methods in enzymology on CD-ROM/Methods in enzymology
  53. Regulation of Mitotic Exit by Cell Cycle Checkpoints: Lessons From Saccharomyces cerevisiae
    Laura Pascual Matellán, Fernando Monje-Casas · 2020 · Genes
  54. Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination
    Susanne Manuela Germann, Vibe H. Oestergaard, Caroline Haas, Pauline Salis, Akira Motegi, Michael Lisby · 2010 · DNA repair
  55. Single-Molecule Study of Lateral Mobility of Epidermal Growth Factor Receptor 2/HER2 on Activation
    Zeyu Xiao, Xinyong Ma, Yaxin Jiang, Zilong Zhao, Bo Lai, Jieying Liao, Jiachang Yue, Xiaohong Fang · 2008 · The Journal of Physical Chemistry B
  56. Functions of Multiple Clamp and Clamp-Loader Complexes in Eukaryotic DNA Replication
    Eiji Ohashi, Toshiki Tsurimoto · 2017 · Advances in experimental medicine and biology
  57. Checkpoints: How to Flag Up Double-Strand Breaks
    Thomas Caspari, Antony M. Carr · 2002 · Current Biology
  58. Chromatin Modifications in DNA Repair
    Ashby J. Morrison, Xuetong Shen · 2006 · Results and problems in cell differentiation
  59. Telomeres and DNA damage checkpoints
    Valeria Viscardi, Michela Clerici, Hugo Cartagena‐Lirola, Maria Pia Longhese · 2004 · Biochimie
  60. Different requirements for the association of ATR–ATRIP and 9-1-1 to the stalled replication forks
    Kanoh, Yutaka, Tamai, Katsuyuki, Shirahige, Katsuhiko · 2006 · Gene
  61. Ddc2 Mediates Mec1 Activation through a Ddc1- or Dpb11-Independent Mechanism
    Amitava Bandhu, John Kang, Kenzo Fukunaga, Greicy H. Goto, Katsunori Sugimoto · 2014 · PLoS Genetics
  62. Interplay Between the Cell Cycle and Double-Strand Break Response in Mammalian Cells
    Kate Beishline, Jane Azizkhan‐Clifford · 2014 · Methods in molecular biology
  63. Dominant TEL1-hy Mutations Compensate for Mec1 Lack of Functions in the DNA Damage Response
    Veronica Baldo, Valentina Testoni, Giovanna Lucchini, Maria Pia Longhese · 2007 · Molecular and Cellular Biology
  64. The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators
    James F. Theis, Carmela Irene, Ann Dershowitz, Renée L. Brost, Michael L. Tobin, Fabiana M. di Sanzo, Jian-Ying Wang, Charles M. Boone, Carol S. Newlon · 2010 · PLoS Genetics
  65. Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts
    Bénédicte Recolin, Siem van der Laan, Domenico Maiorano · 2011 · Nucleic Acids Research
  66. Srs2 enables checkpoint recovery by promoting disassembly of DNA damage foci from chromatin
    ManTek Yeung, Daniel Durocher · 2011 · DNA repair
  67. Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA
    Nathalie Grandin, Michel Charbonneau · 2007 · Nucleic Acids Research
  68. Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair
    Hideaki Ogiwara · 2006 · Nucleic Acids Research
  69. Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage
    Violeta Cordón-Preciado, Sandra Ufano, Avelino Bueno · 2006 · Nucleic Acids Research
  70. Damage site chromatin: open or closed?
    Alexander R. Ball, Kyoko Yokomori · 2011 · Current Opinion in Cell Biology
  71. Regulation of the DNA replication fork: a way to fight genomic instability
    Magali Toueille, Ulrich H�bscher · 2004 · Chromosoma
  72. Efficient DNA double-strand break formation at single or multiple defined sites in the Saccharomyces cerevisiae genome
    Robert Gnügge, Lorraine S. Symington · 2020 · Nucleic Acids Research
  73. A Ddc2-Rad53 Fusion Protein Can Bypass the Requirements forRAD9andMRC1in Rad53 Activation
    Soo-Jung Lee, Jimmy Duong, David F. Stern · 2004 · Molecular Biology of the Cell
  74. Yap1 and Skn7 genetically interact with Rad51 in response to oxidative stress and DNA double-strand break in Saccharomyces cerevisiae
    Dae Gwan Yi, Myung Ju Kim, Ji Eun Choi, Ji‐Hyun Lee, Joohee Jung, Won‐Ki Huh, Woo‐Hyun Chung · 2016 · Free Radical Biology and Medicine
  75. XRad17 Is Required for the Activation of XChk1 But Not XCds1 during Checkpoint Signaling inXenopus
    Rhiannon E. Jones, J. Ross Chapman, Chandrakala Puligilla, Johanne M. Murray, Antony M. Car, Christopher C. Ford, Howard D. Lindsay · 2003 · Molecular Biology of the Cell
  76. Checkpoint arrest signaling in response to UV damage is independent of nucleotide excision repair in Saccharomyces cerevisiae
    Zhang, Hong, Taylor, Jena, Siede, Wolfram · 2003 · Journal of Biological Chemistry
  77. Delineating the position ofrad4+/cut5+ within the DNA-structure checkpoint pathways inSchizosaccharomyces pombe
    Sheila Harris, Caroline Kemplen, Thomas Caspari, Christopher Chan, Howard D. Lindsay, Marius Poitelea, Antony M. Carr, Clive Price · 2003 · Journal of Cell Science
  78. Human RAD18 Interacts with Ubiquitylated Chromatin Components and Facilitates RAD9 Recruitment to DNA Double Strand Breaks
    Akiko Inagaki, Esther Sleddens–Linkels, Wiggert A. van Cappellen, Richard G. Hibbert, Titia K. Sixma, Jan H.J. Hoeijmakers, J. Anton Grootegoed, Willy M. Baarends · 2011 · PLoS ONE
  79. Chromatin Remodeling Factors Isw2 and Ino80 Regulate Checkpoint Activity and Chromatin Structure in S Phase
    Laura J. Lee, Jairo Rodríguez, Toshio Tsukiyama · 2015 · Genetics
  80. NFBD1/Mdc1 Mediates ATR-Dependent DNA Damage Response
    Aimin Peng, Phang‐Lang Chen · 2005 · Cancer Research
  81. Chemical strategies for development of ATR inhibitors
    Sabin Llona‐Minguez, Andreas Höglund, Sylvain A. Jacques, Tobias Koolmeister, Thomas Helleday · 2014 · Expert Reviews in Molecular Medicine
  82. Probing the Mec1ATR Checkpoint Activation Mechanism with Small Peptides
    Paulina H. Wanrooij, Elias Tannous, Sandeep Kumar, Vasundhara M. Navadgi, Peter Burgers · 2015 · Journal of Biological Chemistry
  83. Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts
    Himadri Biswas, Greicy H. Goto, Weibin Wang, Patrick Sung, Katsunori Sugimoto · 2019 · PLoS Genetics
  84. DNA-damage checkpoints: location, location, location
    Jamie L. Wood, Junjie Chen · 2008 · Trends in Cell Biology
  85. Function of Rad17/Mec3/Ddc1 and its partial complexes in the DNA damage checkpoint
    Jerzy Majka, Peter Burgers · 2005 · DNA repair
  86. Checkpoint and Coordinated Cellular Responses to DNA Damage
    Xiaohong Helena Yang, Lee Zou · 2006 · Springer eBooks
  87. Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication
    Greicy H. Goto, Sevil Zencir, Yukinori Hirano, Hiroo Ogi, Andreas Ivessa, Katsunori Sugimoto · 2015 · PLoS Genetics
  88. In Situ Analysis of DNA Damage Response and Repair Using Laser Microirradiation
    Jong‐Soo Kim, Jason T. Heale, Weihua Zeng, Xiangduo Kong, Tatiana B. Krasieva, Alexander R. Ball, Kyoko Yokomori · 2007 · Methods in cell biology
  89. ATR regulates hexavalent chromium-induced S-phase checkpoint through phosphorylation of SMC1
    Timothy P. Wakeman, Bo Xu · 2006 · Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  90. Loss of RPA1 induces Chk2 phosphorylation through a caffeine‐sensitive pathway
    Runa Araya, Itaru Hirai, Cheryl L. Meyerkord, Hong‐Gang Wang · 2004 · FEBS Letters
  91. The Saccharomyces cerevisiae F-Box Protein Dia2 Is a Mediator of S-Phase Checkpoint Recovery from DNA Damage
    Chi Meng Fong, Ashwini Arumugam, Deanna M. Koepp · 2012 · Genetics
  92. Delineation of the role of chromatin assembly and the Rtt101Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast
    Li‐Ting Diao, Chih‐Cheng Chen, Briana K. Dennehey, Sangita Pal, Pingping Wang, Zie-Jie Shen, Angela K. Deem, Jessica K. Tyler · 2017 · PLoS ONE
  93. Damage in transition
    Peter M. Garber, Genevieve M. Vidanes, David Paul Toczyski · 2005 · Trends in Biochemical Sciences
  94. A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1
    Michele Giannattasio, Elena Sommariva, Raffaella Vercillo, Filippo Lippi-Boncambi, Giordano Liberi, Marco Foiani, Paolo Plevani, Marco Muzi-Falconi · 2002 · Proceedings of the National Academy of Sciences
  95. Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis
    Maria Pia Longhese, Ilaria Guerini, Veronica Baldo, Michela Clerici · 2007 · DNA repair
  96. The amino-terminal tails of histones H2A and H3 coordinate efficient base excision repair, DNA damage signaling and postreplication repair in Saccharomyces cerevisiae
    Rithy Meas, Michael J. Smerdon, John J. Wyrick · 2015 · Nucleic Acids Research
  97. NBS 1 directly activates ATR independently of MRE 11 and TOPBP 1
    Masahiko Kobayashi, Naoyuki Hayashi, Minoru Takata, Kenichi Yamamoto · 2013 · Genes to Cells
  98. Modified chromosome structure caused by phosphomimetic H2A modulates the DNA damage response by increasing chromatin mobility in yeast
    Fabiola García Fernández, Brenda R. Lemos, Yasmine Khalil, Renaud Batrin, James E. Haber, Emmanuelle Fabre · 2021 · Journal of Cell Science
  99. Mechanisms Controlling the Integrity of Replicating Chromosomes in Budding Yeast
    Marco Muzi-Falconi, Giordano Liberi, Chiara Lucca, Marco Foiani · 2003 · Cell Cycle
  100. Fission yeast Rad26 responds to DNA damage independently of Rad3
    Tom D. Wolkow, Tamar Enoch · 2003 · BMC Genetics