Dynamics of DNA Double-Strand Breaks Revealed by Clustering of Damaged Chromosome Domains

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Rogakou, E. P., Boon, C., Redon, C., & Bonner, W. M. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.5.905 · Cited by 2,422

The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder

Stewart, G. S., Maser, R. S., Stankovic, T., Bressan, D. A., Kaplan, M. I., Jaspers, N. G. J., Raams, A., Byrd, P. J., Petrini, J. H. J., & Taylor, A. M. R. (1999) · Cell · doi:10.1016/s0092-8674(00)81547-0 · Cited by 1,060

Quantitative Detection of125IdU-Induced DNA Double-Strand Breaks with γ-H2AX Antibody

Sedelnikova, O. A., Rogakou, E. P., Panyutin, I. G., & Bonner, W. M. (2002) · Radiation Research · doi:10.1667/0033-7587(2002)158[0486:qdoiid]2.0.co;2 · Cited by 611

Chromatin Motion Is Constrained by Association with Nuclear Compartments in Human Cells

Chubb, J. R., Boyle, S., Perry, P., & Bickmore, W. A. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00695-4 · Cited by 580

Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends

de Jager, M., van Noort, J., van Gent, D. C., Dekker, C., Kanaar, R., & Wyman, C. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00381-1 · Cited by 512

In situ visualization of DNA double-strand break repair in human fibroblasts

Nelms, B. E., Maser, R. S., MacKay, J. F., Lagally, M. G., & Petrini, J. H. J. (1998) · Science · doi:10.1126/science.280.5363.590 · Cited by 500

Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

Lisby, M., Mortensen, U. H., & Rothstein, R. J. (2003) · Nature Cell Biology · doi:10.1038/ncb997 · Cited by 442

DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex

Mirzoeva, O. K., & Petrini, J. H. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.1.281-288.2001 · Cited by 387

NBS1 Localizes to γ-H2AX Foci through Interaction with the FHA/BRCT Domain

Kobayashi, J., Tauchi, H., Sakamoto, S., Nakamura, A., Morishima, K.-I., Matsuura, S., Kobayashi, T., Tamai, K., Tanimoto, K., & Komatsu, K. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01259-9 · Cited by 306

S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes.

Tashiro, S., Kotomura, N., Shinohara, A., Tanaka, K., Ueda, K., & Kamada, N. (1996) · PubMed · Cited by 165

Quantitative Analysis Reveals Asynchronous and more than DSB-Associated Histone H2AX Phosphorylation after Exposure to Ionizing Radiation

Han, J., Hendzel, M. J., & Allalunis‐Turner, J. (2006) · Radiation Research · doi:10.1667/rr3516.1 · Cited by 37

On the Contribution of Spatial Genome Organization to Cancerous Chromosome Translocations

Soutoglou, E., & Misteli, T. (2008) · JNCI Monographs · doi:10.1093/jncimonographs/lgn017 · Cited by 40

Histone H2AX Phosphorylation in Normal Human Cells Irradiated with Focused Ultrasoft X Rays: Evidence for Chromatin Movement during Repair

Hamada, N., Schettino, G., Kashino, G., Vaid, M., Suzuki, K., Kodama, S., Vojnovic, B., Folkard, M., Watanabe, M., Michael, B. D., et al. (2006) · Radiation Research · doi:10.1667/rr3577.1 · Cited by 37

Boundary Element-Associated Factor 32B Connects Chromatin Domains to the Nuclear Matrix

Pathak, R. U., Rangaraj, N., Kallappagoudar, S., Mishra, K., & Mishra, R. K. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00305-07 · Cited by 37

Enhancing homology-directed repair efficiency with HDR-boosting modular ssDNA donor

Jin, Y.-Y., Zhang, P., Liu, L., Zhao, X. H., Hu, X., Liu, S.-Z., Li, Z., Liu, Q., Wang, J.-Q., Hao, D., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50788-x · Cited by 36

Microbeams in radiation biology: review and critical comparison

Prise, K. M., & Schettino, G. (2010) · Radiation Protection Dosimetry · doi:10.1093/rpd/ncq388 · Cited by 36

IDH1‐mutant cancer cells are sensitive to cisplatin and an IDH1‐mutant inhibitor counteracts this sensitivity

Khurshed, M., Aarnoudse, N., Hulsbos, R., Hira, V. V. V., van Laarhoven, H. W. M., Wilmink, J. W., Molenaar, R. J., & Noorden, C. J. F. V. (2018) · The FASEB Journal · doi:10.1096/fj.201800547r · Cited by 37

Combinatorial DNA Damage Pairing Model Based on X-Ray-Induced Foci Predicts the Dose and LET Dependence of Cell Death in Human Breast Cells

Vadhavkar, N., Pham, C. J., Georgescu, W., Deschamps, T., Heuskin, A., Tang, J., & Costes, S. V. (2014) · Radiation Research · doi:10.1667/rr13792.1 · Cited by 37

Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse Analysis

Georgescu, W., Osseiran, A. I., Rojec, M., Liu, Y., Bombrun, M., Tang, J., & Costes, S. V. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129438 · Cited by 36

Biological Characterization of Low-Energy Ions with High-Energy Deposition on Human Cells

Saha, J., Wilson, P., Thieberger, P., Lowenstein, D. I., Wang, M., & Cucinotta, F. A. (2014) · Radiation Research · doi:10.1667/rr13747.1 · Cited by 35

Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites

Haas, K. T., Lee, M.-Y., Esposito, A., & Venkitaraman, A. R. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx1303 · Cited by 36

A systematic description of MLL fusion gene formation

Wright, R. L., & Vaughan, A. T. (2014) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2014.03.004 · Cited by 36

Laser Microbeams and Optical Tweezers in Ageing Research

Grigaravičius, P., Greulich, K. O., & Monajembashi, S. (2008) · ChemPhysChem · doi:10.1002/cphc.200800725 · Cited by 34

The MCT-1 oncogene product impairs cell cycle checkpoint control and transforms human mammary epithelial cells

Hsu, H.-L., Shi, B., & Gartenhaus, R. B. (2005) · Oncogene · doi:10.1038/sj.onc.1208680 · Cited by 34

Chromosome territory positioning of conserved homologous chromosomes in different primate species

Mora, L., Sánchez, I., Garcia-Caldés, M., & Ponsà, M. (2006) · Chromosoma · doi:10.1007/s00412-006-0064-6 · Cited by 34

The Dynamic Behavior of Chromatin in Response to DNA Double-Strand Breaks

Fernández, F. G., & Fabre, E. (2022) · Genes · doi:10.3390/genes13020215 · Cited by 38

Mutant frequencies and spectra depend on growth state and passage number in cells cultured from transgenic lacZ-plasmid reporter mice

Busuttil, R. A., Rubio, M. Á., Dollé, M. E. T., Campisi, J., & Vijg, J. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.07.006 · Cited by 33

The Tumor Suppressor PML Specifically Accumulates at RPA/Rad51-Containing DNA Damage Repair Foci but Is Nonessential for DNA Damage-Induced Fibroblast Senescence

Münch, S., Weidtkamp-Peters, S., Klement, K., Grigaravicius, P., Monajembashi, S., Salomoni, P., Pandolfi, P. P., Weißhart, K., & Hemmerich, P. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.01345-13 · Cited by 32

Tools to study DNA repair: what's in the box?

Feuerhahn, S., & Egly, J. (2008) · Trends in Genetics · doi:10.1016/j.tig.2008.07.003 · Cited by 34

Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays and protons in action

Ježková, L., Falk, M., Falková, I., Davídková, M., Bačı́ková, A., Štefančíková, L., Vachelová, J., Michaelidesova, A. J., Lukášová, E., Boreyko, A. V., et al. (2013) · Applied Radiation and Isotopes · doi:10.1016/j.apradiso.2013.01.022 · Cited by 33

Comparing Photon and Charged Particle Therapy Using DNA Damage Biomarkers

Ray, S., Cekanaviciute, E., Paulino‐Lima, I. G., Sørensen, B. S., & Costes, S. V. (2018) · International Journal of Particle Therapy · doi:10.14338/ijpt-18-00018.1 · Cited by 33

Mechanism for Recognition of Polyubiquitin Chains: Balancing Affinity through Interplay between Multivalent Binding and Dynamics

Markin, C. J., Xiao, W., & Spyracopoulos, L. (2010) · Journal of the American Chemical Society · doi:10.1021/ja103869x · Cited by 31

Histone and Chromatin Dynamics Facilitating DNA repair

Mohan, C., Das, C., & Tyler, J. K. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103183 · Cited by 35

Dose, LET and Strain Dependence of Radiation-Induced 53BP1 Foci in 15 Mouse Strains Ex Vivo Introducing Novel DNA Damage Metrics

Penninckx, S., Cekanaviciute, E., Degorre, C., Guiet, E., Viger, L., Lucasb, S., & Costes, S. V. (2019) · Radiation Research · doi:10.1667/rr15338.1 · Cited by 31

Subcellular Spatial Correlation of Particle Traversal and Biological Response in Clinical Ion Beams

Niklas, M., Abdollahi, A., Akselrod, M. S., Debus, J., Jäkel, O., & Greilich, S. (2013) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2013.08.043 · Cited by 30

Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2

Chan, E., Teng, G., Corbett, E., Choudhury, K. R., Bassing, C. H., Schatz, D. G., & Krangel, M. S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1310846110 · Cited by 32

Exogenous carbon monoxide protects the bystander Chinese hamster ovary cells in mixed coculture system after alpha-particle irradiation

Han, W., Wu, L., Chen, S., & Yu, K. N. (2009) · Carcinogenesis · doi:10.1093/carcin/bgp301 · Cited by 30

Decay of γ-H2AX foci correlates with potentially lethal damage repair in prostate cancer cells

van Oorschot, B., Hovingh, S., Rodermond, H. M., GÜÇLÜ, A., Losekoot, N., Geldof, A. A., Barendsen, G. W., Stalpers, L. J. A., & Franken, N. A. P. (2013) · Oncology Reports · doi:10.3892/or.2013.2364 · Cited by 30

High Frequency Targeted Mutagenesis Using Engineered Endonucleases and DNA-End Processing Enzymes

Delacôte, F., Perez, C., Guyot, V., Duhamel, M., Rochon, C., Ollivier, N., Macmaster, R., Silva, G. H., Pâques, F., Daboussi, F., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053217 · Cited by 30

Influence of Nuclear Geometry on the Formation of Genetic Rearrangements in Human Cells

Durante, M., Pignalosa, D., Jansen, J. A., Walboomers, X. F., & Ritter, S. (2010) · Radiation Research · doi:10.1667/rr2063.1 · Cited by 30

Mobility and Repair of Damaged DNA: Random or Directed?

Oshidari, R., Mekhail, K., & Seeber, A. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.11.003 · Cited by 31

Radiation microbeams as spatial and temporal probes of subcellular and tissue response

Schettino, G., Rashid, S. T. A., & Prise, K. M. (2010) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2010.01.005 · Cited by 29

JAK2 and genomic instability in the myeloproliferative neoplasms: A case of the chicken or the egg?

Scott, L. M., & Rebel, V. I. (2012) · American Journal of Hematology · doi:10.1002/ajh.23243 · Cited by 31

Increased chromosomal mobility after DNA damage is controlled by interactions between the recombination machinery and the checkpointPreprint

Smith, M. J., Bryant, E. E., & Rothstein, R. J. (2018) · Genes & Development · doi:10.1101/gad.317966.118 · Cited by 29

DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II

Gómez-Herreros, F. (2019) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2019.00141 · Cited by 32

Interaction effects of DNA, RNA-polymerase, and cellular fluid on the local dynamic behaviors of DNA

Hu, W., & Deng, Z. (2020) · Applied Mathematics and Mechanics · doi:10.1007/s10483-020-2595-6 · Cited by 28

Heterochromatinization associated with cell differentiation as a model to study DNA double strand break induction and repair in the context of higher-order chromatin structure

Falk, M., Lukášová, E., Štefančíková, L., Baranová, E., Falková, I., Ježková, L., Davídková, M., Bačı́ková, A., Vachelová, J., Michaelidesova, A. J., et al. (2013) · Applied Radiation and Isotopes · doi:10.1016/j.apradiso.2013.01.029 · Cited by 28

AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells

Plo, I., & López, B. S. (2009) · Oncogene · doi:10.1038/onc.2009.85 · Cited by 28

Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells

Gandhi, M., Stringer, J. R., Nikiforova, M. N., Medvedovic, M., & Nikiforov, Y. E. (2008) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20639 · Cited by 28

Targeting DNA Repair Proteins: A Promising Avenue for Cancer Gene Therapy

Belzile, J.-P., Choudhury, S. A., Cournoyer, D., & Chow, T. Y.-K. (2006) · Current Gene Therapy · doi:10.2174/156652306775515538 · Cited by 28

Chromatin-associated MRN complex protects highly transcribing genes from genomic instability

Salifou, K., Burnard, C., Basavarajaiah, P., Helsmoortel, M., Mac, V., Depierre, D., Grasso, G. I., Franckhauser, C., Beyne, E., Contreras, X., et al. (2021) · Science Advances · doi:10.1126/sciadv.abb2947 · Cited by 27

Integration of DNA damage responses with dynamic spatial genome organization

Stanić, M., & Mekhail, K. (2021) · Trends in Genetics · doi:10.1016/j.tig.2021.08.016 · Cited by 28

Spatial-Temporal Genome Regulation in Stress-Response and Cell-Fate Change

Erenpreisa, J. A., Giuliani, A., Yoshikawa, K., Falk, M., Hildenbrand, G. L., Salmiņa, K., Freivalds, T., Vainshelbaum, N. M., Weidner, J., Sievers, A., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032658 · Cited by 28

Creating localized DNA double-strand breaks with microirradiation

Suzuki, K., Yamauchi, M., Oka, Y., Suzuki, M., & Yamashita, S. (2011) · Nature Protocols · doi:10.1038/nprot.2010.183 · Cited by 27

Advances in the biophysical and molecular bases of radiation cytogenetics

Sasaki, M. S. (2009) · International Journal of Radiation Biology · doi:10.1080/09553000802641185 · Cited by 27

Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites

Mortusewicz, O., Leonhardt, H., & Cardoso, M. C. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21751 · Cited by 27

The early and initiation processes of radiation-induced bystander effects involved in the induction of DNA double strand breaks in non-irradiated cultures

Han, W., Wu, L., Hu, B., Zhang, L., Chen, S., Bao, L., Zhao, Y., Xu, A., & Zhang, Y. (2007) · British Journal of Radiology · doi:10.1259/bjr/44550200 · Cited by 28

CCAAT/Enhancer-Binding Proteins and the Pathogenesis of Retrovirus Infection

Liu, Y., Nonnemacher, M. R., & Wigdahl, B. L. (2009) · Future Microbiology · doi:10.2217/fmb.09.4 · Cited by 27

Roles For Nuclear Organization In The Maintenance Of Genome Stability

Nagai, S., Heun, P., & Gasser, S. M. (2010) · Epigenomics · doi:10.2217/epi.09.49 · Cited by 27

Analysis of DNA Recombination and Repair Proteins in Living Cells by Photobleaching Microscopy

Essers, J., Houtsmuller, A. B., & Kanaar, R. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)08029-3 · Cited by 26

Restoration of G1 chemo/radioresistance and double-strand-break repair proficiency by wild-type but not endonuclease-deficient Artemis

Mohapatra, S., Kawahara, M., Khan, I. S., Yannone, S. M., & Povirk, L. F. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr257 · Cited by 25

Cooperativity between Rad51 and C/EBP family transcription factors modulates basal and Tat‐induced activation of the HIV‐1 LTR in astrocytes

Chipitsyna, G. I., Sawaya, B. E., Khalili, K., & Amini, S. (2006) · Journal of Cellular Physiology · doi:10.1002/jcp.20612 · Cited by 25

An Efficient Method to Generate Chromosomal Rearrangements by Targeted DNA Double-Strand Breaks inDrosophila melanogasterPreprint

Egli, D. M., Hafen, E., & Schaffner, W. (2004) · Genome Research · doi:10.1101/gr.2279804 · Cited by 25

Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization

Mata-Garrido, J., Casafont, Í., Tapia, O., Berciano, M. T., & Lafarga, M. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-016-0312-9 · Cited by 25

γ H2AX in the S Phase after UV Irradiation Corresponds to DNA Replication and Does Not Report on the Extent of DNA Damage

Dhuppar, S., Roy, S., & Mazumder, A. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00328-20 · Cited by 24

Factors That Affect the Formation of Chromosomal Translocations in Cells

Canoy, R. J., Shmakova, A., Karpukhina, A. A., Shepelev, M. V., Germini, D., & Vassetzky, Y. S. (2022) · Cancers · doi:10.3390/cancers14205110 · Cited by 27

Alpha Particles and X Rays Interact in Inducing DNA Damage in U2OS Cells

Sollazzo, A., Brzozowska, B., Cheng, L., Lundholm, L., Haghdoost, S., Scherthan, H., & Wójcik, A. (2017) · Radiation Research · doi:10.1667/rr14803.1 · Cited by 24

Mechanisms leading to nonrandom, nonhomologous chromosomal translocations in leukemia

Gollin, S. M. (2006) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2006.10.002 · Cited by 24

Poetry in motion: Increased chromosomal mobility after DNA damage

Smith, M. J., & Rothstein, R. J. (2017) · DNA repair · doi:10.1016/j.dnarep.2017.06.012 · Cited by 26

Chromatin loops, illegitimate recombination, and genome evolution

Kantidze, O. L., & Razin, S. V. (2009) · BioEssays · doi:10.1002/bies.200800165 · Cited by 23

Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly

Solomon, L. A., Russell, B. A., Watson, L. A., Beier, F., & Bérubé, N. G. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt351 · Cited by 23

Molecular Pathways: Transcription Factories and Chromosomal Translocations

Osborne, C. S. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-3667 · Cited by 23

Actin’ between phase separated domains for heterochromatin repair

Rawal, C. C., Caridi, C. P., & Chiolo, I. (2019) · DNA repair · doi:10.1016/j.dnarep.2019.102646 · Cited by 25

Molecular flexibility of DNA as a key determinant of RAD51 recruitment

Paoletti, F., El-Sagheer, A. H., Allard, J. F., Brown, T. P., Dushek, O., & Esashi, F. (2020) · The EMBO Journal · doi:10.15252/embj.2019103002 · Cited by 24

Mechanisms and impacts of chromosomal translocations in cancers

Wang, J. H. (2012) · Frontiers of Medicine · doi:10.1007/s11684-012-0215-5 · Cited by 23

Generation of cell-based systems to visualize chromosome damage and translocations in living cells

Roukos, V., Burgess, R. C., & Misteli, T. (2014) · Nature Protocols · doi:10.1038/nprot.2014.167 · Cited by 24

Visualization of Heavy Ion Tracks by Labeling 3'-OH Termini of Induced DNA Strand Breaks

Konishi, T., Takeyasu, A., Natsume, T., Furusawa, Y., & Hieda, K. (2011) · Journal of Radiation Research · doi:10.1269/jrr.10097 · Cited by 22

Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination

van Oorschot, B., Uitterhoeve, L. J., Oomen, I., ten Cate, R., Medema, J. P., Vrieling, H., Stalpers, L. J. A., Moerland, P. D., & Franken, N. A. P. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-1966 · Cited by 23

DNA-repair protein distribution along the tracks of energetic ions

Hauptner, A., Krücken, R., Greubel, C., Hable, V., Dollinger, G., Drexler, G. A., Deutsch, M. J., Löwe, R., Friedl, A. A., Dietzel, S., et al. (2006) · Radiation Protection Dosimetry · doi:10.1093/rpd/ncl420 · Cited by 22

α-Particle-induced DNA damage tracks in peripheral blood mononuclear cells of [223Ra]RaCl2-treated prostate cancer patients

Schumann, S., Eberlein, U., Lapa, C., Müller, J., Serfling, S. E., Laßmann, M., & Scherthan, H. (2021) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-020-05170-6 · Cited by 21

Genome-wide profiling of DNA repair proteins in single cells

de Luca, K. L., Rullens, P. M. J., Karpińska, M. A., de Vries, S., Gacek‐Matthews, A., Pongor, L. S., Legube, G., Jachowicz, J. W., Oudelaar, A. M., & Kind, J. (2024) · Nature Communications · doi:10.1038/s41467-024-54159-4 · Cited by 21

AID Biology: A pathological and clinical perspective

Choudhary, M., Tamrakar, A., Singh, A. K., Jain, M., Jaiswal, A. K., & Kodgire, P. (2017) · International Reviews of Immunology · doi:10.1080/08830185.2017.1369980 · Cited by 21

Meiotic Chromosome Contacts as a Plausible Prelude for Robertsonian Translocations

Matveevsky, S. N., Kolomiets, O. L., Богданов, А. С., Алпеева, Е. В., & Bakloushinskaya, I. (2020) · Genes · doi:10.3390/genes11040386 · Cited by 21

53BP1 Repair Kinetics for Prediction of In Vivo Radiation Susceptibility in 15 Mouse Strains

Pariset, E., Penninckx, S., Degorre, C., Guiet, E., Macha, A. L., Cekanaviciute, E., Snijders, A. M., Mao, J., Paris, F., & Costes, S. V. (2020) · Radiation Research · doi:10.1667/rade-20-00122.1 · Cited by 21

High LET-induced H2AX phosphorylation around the Bragg curve

Desai, N., Durante, M., Lin, Z.-W., Cucinotta, F. A., & Wu, H. (2005) · Advances in Space Research · doi:10.1016/j.asr.2005.01.010 · Cited by 21

Mechanisms of insertions at a DNA double-strand break

Min, J., Zhao, J., Zagelbaum, J., Lee, J., Takahashi, S., Cummings, P., Schooley, A., Dekker, J., Gottesman, M. E., Rabadán, R., et al. (2023) · Molecular Cell · doi:10.1016/j.molcel.2023.06.016 · Cited by 21

Repeated exposure of human fibroblasts to ionizing radiation reveals an adaptive response that is not mediated by interleukin-6 or TGF-β

Dieriks, B. V., Vos, W. H. D., Baatout, S., & Oostveldt, P. V. (2011) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.07.002 · Cited by 20

Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture

Harding, S. M., & Greenberg, R. A. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00103 · Cited by 19

Correlation of the absorbed dose to the blood and DNA damage in leukocytes after internal ex-vivo irradiation of blood samples with Ra-224

Schumann, S., Eberlein, U., Müller, J., Scherthan, H., & Laßmann, M. (2018) · EJNMMI Research · doi:10.1186/s13550-018-0422-4 · Cited by 19

A high-throughput alpha particle irradiation system for monitoring DNA damage repair, genome instability and screening in human cell and yeast model systems

Stanley, F. K. T., Berger, N. D., Pearson, D. D., Danforth, J. M., Morrison, H., Johnston, J. E., Warnock, T. S., Brenner, D. R., Chan, J. A.-W., Pierce, G., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa782 · Cited by 22

In Situ Analysis of DNA Damage Response and Repair Using Laser Microirradiation

Kim, J., Heale, J. T., Zeng, W., Kong, X., Krasieva, T. B., Ball, A. R., & Yokomori, K. (2007) · Methods in cell biology · doi:10.1016/s0091-679x(06)82013-3 · Cited by 20

Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited

Gué, M., Sun, J., & Boudier, T. (2006) · BMC Cancer · doi:10.1186/1471-2407-6-20 · Cited by 19

Increased complexity of radiation-induced chromosome aberrations consistent with a mechanism of sequential formation

Anderson, R. M., Papworth, D. G., Stevens, D. L., Sumption, N. D., & GOODHEAD, D. T. (2005) · Cytogenetic and Genome Research · doi:10.1159/000087511 · Cited by 19

Epstein−Barr virus reactivation induces MYC‐IGH spatial proximity and t(8;14) in B cells

Sall, F. B., Shmakova, A., Karpukhina, A. A., Tsfasman, T., Lomov, N. A., Canoy, R. J., Boutboul, D., Oksenhendler, É., Touré, A. O., Lipinski, M., et al. (2023) · Journal of Medical Virology · doi:10.1002/jmv.28633 · Cited by 18

Mechanism of protection of bystander cells by exogenous carbon monoxide: Impaired response to damage signal of radiation-induced bystander effect

Han, W., Yu, K. N., Wu, L., Wu, Y., & Wang, H. Z. (2011) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.02.011 · Cited by 18

Interpreting Chromosomal Rearrangements in the Context of 3-Dimentional Genome Organization: A Practical Guide for Medical Genetics

Fishman, V., Salnikov, P., & Баттулин, Н. Р. (2018) · Biochemistry (Moscow) · doi:10.1134/s0006297918040107 · Cited by 18

Differences in nuclear positioning of 1q12 pericentric heterochromatin in normal and tumor B lymphocytes with 1q rearrangements

Barki‐Celli, L., Lefebvre, C., Baccon, P. L., Nadeau, G., Bonnefoix, T., Usson, Y., Vourc’h, C., Khochbin, S., Leroux, D., & Callanan, M. B. (2005) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20179 · Cited by 18

Downregulation of KIF2C and TEKT2 is associated with male infertility and testicular carcinoma

Cao, H., Wan, Z., Wang, F., Liu, Z., Li, X., & Hou, J. (2021) · Aging · doi:10.18632/aging.203583 · Cited by 17

Sensitizing thermochemotherapy with a PARP1-inhibitor

Oei, A. L., Vriend, L. E. M., van Leeuwen, C. M., Rodermond, H. M., ten Cate, R., Westermann, A. M., Stalpers, L. J. A., Crezee, J., Kanaar, R., Kok, H. P., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.11422 · Cited by 17

Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements

Evdokimova, V. N., Gandhi, M., Nikitski, A. V., Bakkenist, C. J., & Nikiforov, Y. E. (2018) · Oncotarget · doi:10.18632/oncotarget.24434 · Cited by 21

3D Genome Organization Influences the Chromosome Translocation Pattern

McCord, R. P., & Balajee, A. S. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0593-1_8 · Cited by 18

Geomagnetic Shielding Enhances Radiation Resistance by Promoting DNA Repair Process in Human Bronchial Epithelial Cells

Xue, X., Ali, Y. F., Liu, C., Hong, Z., Luo, W., Nie, J., Li, B., Jiao, Y., & Liu, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239304 · Cited by 17

DNA double-strand breaks: linking gene expression to chromosome morphology and mobility

Zhang, Y., & Heermann, D. W. (2013) · Chromosoma · doi:10.1007/s00412-013-0432-y · Cited by 18

Decay of γ-H2AX foci correlates with potentially lethal damage repair and P53 status in human colorectal carcinoma cells

van Oorschot, B., Oei, A. L., Nuijens, A. C., Rodermond, H. M., Hoeben, R., Stap, J., Stalpers, L. J. A., & Franken, N. A. P. (2013) · Cellular & Molecular Biology Letters · doi:10.2478/s11658-013-0113-0 · Cited by 17

Local changes of higher-order chromatin structure during DSB-repair

Falk, M., Lukášová, E., Gabrielová, B., Ondřej, V., & Kozubek, S. (2008) · Journal of Physics Conference Series · doi:10.1088/1742-6596/101/1/012018 · Cited by 17

Chromosomal Organization: Mingling with the Neighbors

Aten, J. A., & Kanaar, R. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040155 · Cited by 17

Recombination Mechanisms

Heyer, W., & Kanaar, R. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.09.025 · Cited by 17

Comparative Study of the Effect of Radiation Delivered by Lutetium-177 or Actinium-225 on Anti-GD2 Chimeric Antigen Receptor T Cell Viability and Functions

Sodji, Q., Forsberg, M., Cappabianca, D., Kerr, C., Sarko, L. E., Shea, A., Adam, D., Eickhoff, J., Ong, I. M., Hernandez, R. T., et al. (2023) · Cancers · doi:10.3390/cancers16010191 · Cited by 12

Chromatin dynamics at DNA breaks: what, how and why?

Lebeaupin, T., 1 CNRS, U. 6., Sellou, H., Timinszky, G., & Huet, S. (2015) · AIMS Biophysics · doi:10.3934/biophy.2015.4.458 · Cited by 17

Distribution of copy number variations and rearrangement endpoints in human cancers with a review of literature

Mirzaei, G., & Petreaca, R. C. (2021) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2021.111773 · Cited by 16

Chromatin mobility is increased at sites of DNA double-strand breaks

Krawczyk, P. M., Borovski, T., Stap, J., Cijsouw, T., ten Cate, R., Medema, J. P., Kanaar, R., Franken, N. A. P., & Aten, J. A. (2012) · Journal of Cell Science · doi:10.1242/jcs.089847 · Cited by 164

Positional stability of single double-strand breaks in mammalian cells

Soutoglou, E., Dorn, J. F., Sengupta, K., Jasin, M., Nussenzweig, A., Ried, T., Danuser, G., & Misteli, T. (2007) · Nature Cell Biology · doi:10.1038/ncb1591 · Cited by 509

Dynamics of double strand breaks and chromosomal translocations

Iarovaia, O. V., Rubtsov, M. A., Ioudinkova, E. S., Tsfasman, T., Razin, S. V., & Vassetzky, Y. S. (2014) · Molecular Cancer · doi:10.1186/1476-4598-13-249 · Cited by 52

Dynamics of Double-Strand Breaks: Implications for the Formation of Chromosome Translocations

Gothe, H. J., Minneker, V., & Roukos, V. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0593-1_3 · Cited by 14

A meeting at risk: Unrepaired DSBs go for broke

Guénolé, A., & Legube, G. (2017) · Nucleus · doi:10.1080/19491034.2017.1380138 · Cited by 14