Dynamics of DNA Double-Strand Breaks Revealed by Clustering of Damaged Chromosome Domains

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

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Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends

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DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex

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NBS1 Localizes to γ-H2AX Foci through Interaction with the FHA/BRCT Domain

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S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes.

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Nefarious NTRK oncogenic fusions in pediatric sarcomas: Too many to Trk

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Microirradiation techniques in radiobiological research

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Induction and disappearance of γH2AX foci and formation of micronuclei after exposure of human lymphocytes to60Co γ-rays and p(66)+ Be(40) neutrons

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DNA damage-induced inflammation and nuclear architecture

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Single α-particle irradiation permits real-time visualization of RNF8 accumulation at DNA damaged sites

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Genetic instability is prevented by Mrc1‐dependent spatio‐temporal separation of replicative and repair activities of homologous recombination

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Repositioning of ETO gene in cells treated with VP‐16, an inhibitor of DNA‐Topoisomerase II

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Clustering of double strand break-containing chromosome domains is not inhibited by inactivation of major repair proteins

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Elevated sodium chloride concentrations enhance the bystander effects induced by low dose alpha-particle irradiation

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Dynamics of the DNA damage response: insights from live-cell imaging

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DNA damage and repair kinetics after microbeam radiation therapy emulation in living cells using monoenergetic synchrotron X-ray microbeams

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Analysis of the Mobility of DNA Double-Strand Break-Containing Chromosome Domains in Living Mammalian Cells

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3D Genome Organization: Causes and Consequences for DNA Damage and Repair

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SUMO-Based Regulation of Nuclear Positioning to Spatially Regulate Homologous Recombination Activities at Replication Stress Sites

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Visualizing the Genome: Experimental Approaches for Live-Cell Chromatin Imaging

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Influence of nuclear structure on the formation of radiation-induced lethal lesions

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Spatial Association of Homologous Pericentric Regions in Human Lymphocyte Nuclei during Repair

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RAD51 Inhibition Shows Antitumor Activity in Hepatocellular Carcinoma

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Defining the Damaged DNA Mobility Paradox as Revealed by the Study of Telomeres, DSBs, Microtubules and Motors

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Chronic exposure to sublethal doses of radiation mimetic Zeocin™ selects for clones deficient in homologous recombination

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Differential Dynamics of ATR‐Mediated Checkpoint Regulators

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Dynamics of Double-Strand Breaks: Implications for the Formation of Chromosome Translocations

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The Broken MLL Gene Is Frequently Located Outside the Inherent Chromosome Territory in Human Lymphoid Cells Treated with DNA Topoisomerase II Poison Etoposide

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Role of chromosome 1 pericentric heterochromatin (1q) in pathogenesis of myelodysplastic syndromes: Report of 2 new cases

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Spatial Positioning of All 24 Chromosomes in the Lymphocytes of Six Subjects: Evidence of Reproducible Positioning and Spatial Repositioning following DNA Damage with Hydrogen Peroxide and Ultraviolet B

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Radiothérapie et biomarqueurs de la réparation de l’ADN

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Preferential accessibility to specific genomic loci for the repair of double-strand breaks in human cells

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Roles for the 3D genome in the cell cycle, DNA replication, and double strand break repair

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Single nucleosome imaging reveals principles of transient multiscale chromatin reorganization triggered by histone ADP-ribosylation at DNA lesions

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Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast

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Testicular orphan nuclear receptor 4 is associated with the radio-sensitivity of prostate cancer

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Frequency of close positioning of chromosomal loci detected by FRET correlates with their participation in carcinogenic rearrangements in human cells

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A tool for enhancement and scoring of DNA repair foci

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A newly established GDL1 cell line from gpt delta mice well reflects the in vivo mutation spectra induced by mitomycin C

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Chromosome organization and gene control: It is difficult to see the picture when you are inside the frame

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Bleomycin-induced γH2AX foci map preferentially to replicating domains in CHO9 interphase nuclei

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Interaction of heavy ions with nuclear chromatin: Spatiotemporal investigations of biological responses in a cellular environment

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3D view of chromosomes, DNA damage, and translocations

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Homologous Recombination is Involved in the Repair Response of Mammalian Cells to Low Doses of Tritium

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A meeting at risk: Unrepaired DSBs go for broke

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Large Field Alpha Irradiation Setup for Radiobiological Experiments

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ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocationsPreprint

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Specificity of cancer-related chromosomal translocations is linked to proximity after the DNA double-strand break and subsequent selection

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Suppression of innate immune signaling molecule, MAVS, reduces radiation-induced bystander effect

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BRCA1 and BRCA2 in Breast Cancer Predisposition and Recombination Control

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Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity

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A role for epigenetics in the formation of chromosome translocations in acute leukemia

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A Tale of Two States: Pluripotency Regulation of Telomeres

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Single-molecule fluorescence imaging techniques reveal molecular mechanisms underlying deoxyribonucleic acid damage repair

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Radiation-induced DNA double-strand breaks in cortisol exposed fibroblasts as quantified with the novel foci-integrated damage complexity score (FIDCS)

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Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach

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Ion Irradiation as a Tool to Reveal the Spatiotemporal Dynamics of DNA Damage Response Processes

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Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation

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Dynamics of radiation induced γH2AX foci in chromatin subcompartments of mouse pachytene spermatocytes and round spermatids

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Direct Quantitative Monitoring of Homology-Directed DNA Repair of Damaged Telomeres

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Catch the live show: Visualizing damaged DNA in vivo

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Chromatin control in double strand break repair

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Differential Recruitment of DNA Repair Proteins KU70/80 and RAD51 upon Microbeam Irradiation with α-Particles

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Beyond inversions and deletions: the evolutionary and functional insights from translocations, fissions, and fusions in animal genomes

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Engineered Meganucleases for Genome Engineering Purposes

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Réparation de l’ADN

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In vivo imaging of DNA double-strand break induced telomere mobility during alternative lengthening of telomeres

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Limited Repair of Critical DNA Damage in Cells Exposed to Low Dose Radiation

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Influence of track directions on the biological consequences in cells irradiated with high LET heavy ions

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Aggregative organization enhances the DNA end‐joining process that is mediated by DNA‐dependent protein kinase

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Mechanistic Sequence of Histone Deacetylase Inhibitors and Radiation Treatment: An Overview

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hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan

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Emerging role of radiopharmaceutical therapy in oncology: advances, challenges, and future directions

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Targeted nuclear irradiation with a proton microbeam induces oxidative DNA base damage and triggers the recruitment of DNA glycosylases OGG1 and NTH1

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p53 binding protein 1 foci as a biomarker of DNA double strand breaks induced by ionizing radiation

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Repair of DNA Double-Strand Breaks

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Radiobiologic Principles

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A simple microscopy setup for visualizing cellular responses to DNA damage at particle accelerator facilities

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