Control of Peripheral Nerve Myelination by the ß-Secretase BACE1
Willem, Michael, Garratt, Alistair N., Novak, Bozidar, Citron, Martin, Kaufmann, Steve, Rittger, Andrea, DeStrooper, Bart, Saftig, Paul, Birchmeier, Carmen, Haass, Christian·2006·Science
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- Network features and pathway analyses of a signal transduction cascadeRyoji Yamashima · 2009 · Frontiers in Neuroinformatics
- Fabrication, characterization and biocompatibility of collagen/oxidized regenerated cellulose-Ca composite scaffold for carrying Schwann cellsWenli Song, Yuhua Zhao, Yadong Wu, Zhipeng Li, Hui Lv, Siyu Li, Yue Jiang, Chun Song, Fang Wang, Yudong Huang · 2018 · International Journal of Biological Macromolecules
- Peptidomimetic BACE1 Inhibitors for Treatment of Alzheimer's Disease: Design and EvolutionUlrich Iserloh, Jared N. Cumming · 2010 · Methods and principles in medicinal chemistry
- AAV mediated delivery of a novel anti-BACE1 VHH reduces Abeta in an Alzheimer’s disease mouse modelMelvin Y. Rincón, Lujia Zhou, Catherine Marneffe, Iryna Voytyuk, Yessica Wouters, Maarten Dewilde, Sandra I. Duqué, Cécile Vincke, Yona Levites, Todd Eliot Golde et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- A neuronal PIP3-dependent program of oligodendrocyte precursor recruitment and myelinationGeorg L. Wieser · 2017 · eDiss (Georg-August-Universität Göttingen)
- Upregulation of SET Expression by BACE1 and its Implications in Down SyndromeXiaozhu Zhang, Yili Wu, Xiaoling Duan, Wei Chen, Haiyan Zou, Mingming Zhang, Shuting Zhang, Fang Cai, Weihong Song · 2014 · Molecular Neurobiology
- BACE1-dependent metabolism of neuregulin 1: Bridging the gap in explaining the occurrence of schizophrenia-like symptoms in Alzheimer's disease with psychosis?Bruno Vincent, Subhamita Maitra · 2023 · Ageing Research Reviews
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- The BACE1-generated C-terminal fragment of the neural cell adhesion molecule 2 (NCAM2) promotes BACE1 targeting to Rab11-positive endosomesRyan Keable, Shangfeng Hu, Grant Pfundstein, Irina Kozlova, Feifei Su, Ximing Du, Hongyuan Yang, Jenny Margaret Gunnersen, Melitta Schachner, Iryna Leshchyns’ka et al. · 2022 · Cellular and Molecular Life Sciences
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- Genetic and molecular biology of gastric cancer among Iranian patients: an updateMohammad Reza Abbaszadegan, Majid Mojarrad, Hamid Reza Rahimi, Meysam Moghbeli · 2022 · Egyptian Journal of Medical Human Genetics
- Critical analysis of the use of β-site amyloid precursor protein-cleaving enzyme 1 inhibitors in the treatment of Alzheimer's diseaseGenevieve M. Evin, Adel Barakat · 2014 · Degenerative Neurological and Neuromuscular Disease
- Troubleshooting methods for APP processing in vitroMagdalena Sastre · 2010 · Journal of Pharmacological and Toxicological Methods
- Copper and cuproptosis: mechanisms, biology, and roles in diseaseFudi Wang, Wenye Liu, Cong Tao, Liyun Chen, Ningjun Ni, Liujing Huang, Yueyang Ouyang, Qianqian Shi, Dandan Wu, Chenghua Li et al. · 2026 · 中国科学通报:英文版
- Membrane-Targeted Quantum Dot-Based BACE1 Activity Sensors for In Vitro and In Cellulo AssaysCarlota Tosat‐Bitrián, Jesús Alejandro Bueso de Barrio, Michael H. Stewart, Kimihiro Susumu, Igor L. Medintz, Sebastián A. Dı́az, Valle Palomo · 2024 · ACS Applied Materials & Interfaces
- Pharmacological applications of a novel neoepitope antibody to a modified amyloid precursor protein-derived beta-secretase productGuoxin Wu, Sethu Sankaranarayanan, Donna L. Montgomery, Adam J. Simon, Zhiqiang An, Mary J. Savage · 2011 · Protein & Cell
- Silencing of Amyloid Precursor Protein Expression Using a New Engineered Delta RibozymeManel Ben Aissa, Marie-Claude April, Lucien Junior Bergeron, Jean‐Pierre Perreault, Georges Lévesque · 2012 · International Journal of Alzheimer s Disease
- Can brain impermeable BACE1 inhibitors serve as anti-CAA medicine?Jianming Li, Liling Huang, Fei Liu, Beisha Tang, Xiao‐Xin Yan · 2017 · BMC Neurology
- Schwann Cell Plasticity in Peripheral Nerve Regeneration after InjuryEmilia Manole, Alexandra Eugenia Bastian, Ana Maria Oproiu, Monica Teodora Neagu, Carolina Constantin, Gheorghița Isvoranu · 2020 · IntechOpen eBooks
- Expression of BACE1 in the Rat Carotid BodyChaohong Li, Baosheng Zhao, Ya-Nan Fan, Xianglei Jia, Yuzhen Liu · 2020 · Frontiers in Physiology
- Co-Immobilized Capillary Enzyme Reactor Based on Beta-Secretase1 and Acetylcholinesterase: A Model for Dual-Ligand ScreeningAdriana Ferreira Lopes Vilela, Vitor Eduardo Narciso dos Reis, Carmen Lúcia Cardoso · 2021 · Frontiers in Chemistry
- Postnatal neuronalBace1deletion impairs neuroblast and oligodendrocyte maturationMarc Benoit, Mabintou Darboe, Brati Das, Yingying Ge, John Zhou, Annie Y. Yao, Wanxia He, Riqiang Yan, Xiangyou Hu · 2022 · Human Molecular Genetics
- In silico analysis of neuregulin 1 evolution in vertebratesChih-Fong Chou, Miwako Ozaki · 2009 · Bioscience Reports
- BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate GyrusHailong Hou, Qingyuan Fan, Wanxia He, Hoonkyo Suh, Xiangyou Hu, Riqiang Yan · 2017 · Stem Cell Reports
- Regulation of proBACE1 by GlycosaminoglycansDavid Henry Small, David William Klaver, Marie Beckman · 2008 · Neurodegenerative Diseases
- Computational Insights into the Development of Novel Therapeutic Strategies for Alzheimer’s DiseaseRajeev S. Prabhakar · 2009 · Future Medicinal Chemistry
- Alzheimer’s DiseaseMartin Rhys Farlow · 2010 · Elsevier eBooks
- RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer’s disease mouse modelsYongeun Cho, Jeongmi Lee, Jun‐Sik Kim, Yeji Jeon, Sukmin Han, Heewon Cho, Yeongyeong Lee, Tai Kyoung Kim, Ju‐Mi Hong, Yujeong Lee et al. · 2025 · Animal Cells and Systems
- BACE1 : Biological Functions and Involvement in the Pathophysiology of Alzheimer's Disease and Other Neurological DisordersMarija Bartolić, Anita Bosak · 2025 · BioFactors
- Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK PathwaysYongeun Cho, Jeongmi Lee, Bo Youn Choi, Jin‐Ho Yun, Sukmin Han, Seung Hyun Baek, Jinsu Park, Yoonsuk Cho, Hark Kyun Kim, Eunae Kim et al. · 2026 · MedComm
- Identifying Potential BACE1 Inhibitors from the ChEMBL Database Using Machine Learning and Atomistic Simulation ApproachesQuang Tung Dao, Do Thi Mai Dung, Quynh Mai Thai, Phuong‐Thao Tran, Son Tung Ngo, Trung Hai Nguyen · 2026 · ACS Omega
- Neuregulin-1 facilitates myelin regeneration through microglia-mediated mechanisms in a mouse model of chronic demyelinationSeyyed Mohyeddin Ziaee, S Hiva Nemati, Hardeep Kataria, Elisabet Jakova, Seyed Mojtaba Hosseini, Pejman Ghelich, Graham A. McLeod, Ali Tamayol, Voon Wee Yong, Soheila Karimi‐Abdolrezaee · 2026 · Nature Communications
- Associations of CSF BACE1 with amyloid pathology, neurodegeneration, and cognition in Alzheimer’s diseaseFeng Gao, Mengguo Zhang, Qiong Wang, Ming Ni, Chang Liu, Kexue Deng, Qiang Xie, Shicung Wang, Jiong Shi, Yong Shen · 2024 · Acta Neuropathologica
- Proteases in the Nervous SystemHolger Cynis, Stefan F. Lichtenthaler, Leona Wagner, Hans‐Ulrich Demuth · 2013 · Springer eBooks
- Macrophage-specific deletion of BACE1 does not enhance macrophage recruitment to the injured peripheral nerveJohn A. Fissel, Mohamed H. Farah · 2020 · Journal of Neuroimmunology
- Chronic BACE-1 Inhibitor Administration in TASTPM Mice (APP KM670/671NL and PSEN1 M146V Mutation): An EEG StudySusanna Lopez, Claudio Del Percio, Gianluigi Forloni, Angelisa Frasca, Wilhelmus H. I. M. Drinkenburg, Roberta Lizio, Giuseppe Noce, Raffaele Ferri, Andrea Soricelli, Fabrizio Stocchi et al. · 2020 · International Journal of Molecular Sciences
- Prospects and Challenges for Alzheimer TherapeuticsMichael S. Wolfe · 2016 · Elsevier eBooks
- Activation of Transient Receptor Potential Vanilloid-3 Channels in Keratinocytes Induces Pruritus in HumansHye One Kim, Hye One Kim, Won‐Sik Shim, I Kwak, Bo Young Chung, Seok Young Kang, C Park, Hye One Kim · 2021 · Acta Dermato Venereologica
- Avoiding Collateral Damage in Alzheimer's Disease TreatmentCharles C. Glabe · 2006 · Science
- Molecular Aspects of Memory Dysfunction in Alzheimer’s DiseaseJeannie Chin, Erik D. Roberson, Lennart Mucke · 2008 · Elsevier eBooks
- ALZHEIMER'S DISEASEMartin Rhys Farlow · 2007 · CONTINUUM Lifelong Learning in Neurology
- Fishing for function – distinct roles of Bace1 and Bace2 in Zebrafish developmentJochen Walter · 2013 · Journal of Neurochemistry
- Polypharmacological profiling across protein target families and cellular pathways using the multiplexed cell-based assay platform safetyProfiler reveals efficacy, potency and side effects of drugsLukša Popović, Ben Brankatschk, Giulia Palladino, Moritz J. Rossner, Michael C. Wehr · 2024 · Biomedicine & Pharmacotherapy
- Early Animal Origin of BACE1 APP/Aβ Proteolytic FunctionJames A. Langeland, Lillian Baumann, Eva M. DeYoung, Raphaela Angelina Varella, Nkatha Mwenda, Alejandro Aguirre, D. Blaine Moore · 2024 · Biology
- Tight Spaces, Tighter Signals: Spatial Constraints as Drivers of Peripheral MyelinationLuca Bartesaghi, Basilio Giangreco, Vanessa Chiappini, María Fernanda Veloz Castillo, Martina Monaco, Jean-Jaques Médard, Giovanna Gambarotta, Marco Agus, Corrado Calì · 2025 · Cells
- Progress in the development of anti-amyloid drugs for treatment of Alzheimer’s diseaseYoshitsugu Shitaka, Yasuyuki Mitani, Akira Nagakura, Akira Miyake, Nobuya Matsuoka · 2010 · Folia Pharmacologica Japonica
- BACE1 in PV interneuron tunes hippocampal CA1 local circuits and resets priming of fear memory extinctionXuansheng Xiao, Xiaotong Wang, Ke Zhu, Lijuan Li, Ying He, Jinglan Zhang, Linying Li, Hanning Hu, Yanqiu Cui, Jianliang Zhang et al. · 2023 · Molecular Psychiatry
- Comparative studies of amyloid properties of muscles proteins and brain Aβ-peptides and identification of approaches to destruction of their amyloids in vitroA. G. Bobylev, Liya G. Bobyleva, Ivan M. Vikhlyantsev, Anna D. Ulanova, N. N. Salmov, Z. A. Podlubnaya · 2013 · BIOPHYSICS
- Addressing the Complex Etiology of Alzheimer‘s Disease: the Role of P25/Cdk5Alison E. Mungenast, Li‐Huei Tsai · 2011 · Future Neurology
- β-Secretase InhibitionRobert J. Vassar · 2016 · Elsevier eBooks
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- Tau and beta-amyloid in Alzheimer’s Disease: Theories, treatments strategies, and future directionsJake Colautti, Kien Nagales · 2020 · The Meducator
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