The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race

Aravin, Alexei A., Hannon, Gregory J., Brennecke, Julius·2007·Science
DOI 10.1126/science.1146484

Cited by (999)

Items 201–300 of 999

  1. Small RNAs: Keeping Stem Cells in Line
    Bradford Stadler, Hannele Ruohola‐Baker · 2008 · Cell
  2. piRNA pathway is not required for antiviral defense in Drosophila melanogaster
    Marine J. Petit, Vanesa C. Mongelli, Lionel Frangeul, Hervé Blanc, Francis M. Jiggins, Maria‐Carla Saleh · 2016 · Proceedings of the National Academy of Sciences
  3. PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition
    Li Liu, Hongying Qi, Jianquan Wang, Haifan Lin · 2011 · Development
  4. Endo‐siRNAs depend on a new isoform of loquacious and target artificially introduced, high‐copy sequences
    Julia Verena Hartig, Stephanie Esslinger, Romy Böttcher, Kuniaki Saito, Klaus Förstemann · 2009 · The EMBO Journal
  5. Selfish genetic elements
    J. Arvid Ågren, Andrew G. Clark · 2018 · PLoS Genetics
  6. The PiRNA Response to Retroviral Invasion of the Koala Genome
    Tianxiong Yu, Birgit S. Koppetsch, Sara Pagliarani, Stephen Douglas Johnston, Noah J. Silverstein, Jeremy Luban, Keith J. Chappell, Zhiping Weng, William E. Theurkauf · 2019 · Cell
  7. Phylogenetic Origin and Diversification of RNAi Pathway Genes in Insects
    Daniel Dowling, Thomas Pauli, Alexander Donath, Karen Meusemann, Lars Podsiadłowski, Malte Petersen, Ralph S. Peters, Christoph Mayer, Shanlin Liu, Xin Yu Zhou et al. · 2016 · Genome Biology and Evolution
  8. Endogenous short RNAs generated by Dicer 2 and RNA-dependent RNA polymerase 1 regulate mRNAs in the basal fungus Mucor circinelloides
    Francisco Esteban Nicolás, Simon Moxon, Juan P. de Haro, Silvia Calo, Igor V. Grigoriev, Santiago Torres‐Martínez, Vincent Moulton, Rosa M. Ruiz‐Vázquez, Tamás Dalmay · 2010 · Nucleic Acids Research
  9. Epigenetic Disruption of the PIWI Pathway in Human Spermatogenic Disorders
    Holger Heyn, Humberto J. Ferreira, L. Bassas, Sandra Bonache, Sergi Sayols, Juan Sandoval, Manel Esteller, Sara Larriba · 2012 · PLoS ONE
  10. Target-Triggered Three-Way Junction Structure and Polymerase/Nicking Enzyme Synergetic Isothermal Quadratic DNA Machine for Highly Specific, One-Step, and Rapid MicroRNA Detection at Attomolar Level
    Qing Zhang, Feng Chen, Feng Xu, Yongxi Zhao, Chunhai Fan · 2014 · Analytical Chemistry
  11. Spermatogenesis
    Diana S. Chu, Diane C. Shakes · 2012 · Advances in experimental medicine and biology
  12. miRNA cassettes in viral vectors: Problems and solutions
    Ying Poi Liu, Ben Berkhout · 2011 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  13. Regulation of spermatogenesis by small non-coding RNAs: Role of the germ granule
    Sara de Mateo, Paolo Sassone‐Corsi · 2014 · Seminars in Cell and Developmental Biology
  14. Non-specific activation of antiviral immunity and induction of RNA interference may engage the same pathway in the Pacific white leg shrimp Litopenaeus vannamei
    Yannick Labreuche, Artur Veloso, Enrique de la Vega, Paul S. Gross, Robert W Chapman, Craig L. Browdy, Gregory W. Warr · 2010 · Developmental & Comparative Immunology
  15. To be or not to be a piRNA: genomic origin and processing of piRNAs
    Adrien Le Thomas, Katalin Fejes Tóth, Alexei A. Aravin · 2014 · Genome biology
  16. Co-evolution between transposable elements and their hosts: a major factor in genome size evolution?
    J. Arvid Ågren, Stephen Wright · 2011 · Chromosome Research
  17. Applied Bioinformatics
    David A. Hendrix · 2019
  18. Non-coding RNAs in homeostasis, disease and stress responses: an evolutionary perspective
    Paulo Amaral, Marcel E. Dinger, John S. Mattick · 2013 · Briefings in Functional Genomics
  19. Ancestral Roles of Small RNAs: An Ago-Centric Perspective
    Leemor Joshua‐Tor, Gregory J. Hannon · 2010 · Cold Spring Harbor Perspectives in Biology
  20. Macroalgal Proteins: A Review
    Ronan O’ O' Brien, María Hayes, Gary N. Sheldrake, Brijesh Kumar Tiwari, Pamela J. Walsh · 2022 · Foods
  21. Reduced pachytene piRNAs and translation underlie spermiogenic arrest in Maelstrom mutant mice
    Julio M Castaneda, Pavol Genzor, Godfried W. van der Heijden, Ali Sarkeshik, John R. Yates, Nicholas T. Ingolia, Alex L. Bortvin · 2014 · The EMBO Journal
  22. Deep Sequencing of Organ- and Stage-Specific microRNAs in the Evolutionarily Basal Insect Blattella germanica (L.) (Dictyoptera, Blattellidae)
    Alexandre S. Cristino, Érica Donato Tanaka, Mercedes Rubio, Maria‐Dolors Piulachs, Xavier Bellés · 2011 · PLoS ONE
  23. AGO1 Homeostasis Involves Differential Production of 21-nt and 22-nt miR168 Species by MIR168a and MIR168b
    Hervé Vaucheret · 2009 · PLoS ONE
  24. Small noncoding RNAs: Biogenesis, function, and emerging significance in toxicology
    Supratim Choudhuri · 2010 · Journal of Biochemical and Molecular Toxicology
  25. Evolution of genome structure in the Drosophila simulans species complex
    Mahul Chakraborty, Ching-Ho Chang, Danielle E. Khost, Jeffrey Vedanayagam, Jeffrey R. Adrion, Yi Liao, Kristi L. Montooth, Colin D. Meiklejohn, Amanda M. Larracuente, J. J. Emerson · 2021 · Genome Research
  26. Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy
    Perry B. Hackett, David A. Largaespada, Kirsten C. Switzer, Laurence J.N. Cooper · 2013 · Translational research
  27. Regulatory long non-coding RNA and its functions
    Yong Huang, Ning Liu, Jian‐Ping Wang, Yu Qin Wang, Xue Li Yu, Zhan Bin Wang, Xiang Chao Cheng, Quan Zou · 2012 · Journal of Physiology and Biochemistry
  28. A serum piRNA signature as promising non-invasive diagnostic and prognostic biomarkers for colorectal cancer
    Ailin Qu, Wenfei Wang, Yongmei Yang, Xin Zhang, Yuhuan Dong, Guixi Zheng, Qiuyan Wu, Mingjin Zou, Lutao Du, Yunshan Wang et al. · 2019 · Cancer Management and Research
  29. Hyb: A bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data
    Anthony J. Travis, Jonathan Moody, Aleksandra Helwak, David W. Tollervey, Grzegorz Kudla · 2013 · Methods
  30. CRISPR/Cas and Cmr modules, mobility and evolution of adaptive immune systems
    Shiraz Ali Shah, Roger A. Garrett · 2010 · Research in Microbiology
  31. The piRNA pathway in Drosophila ovarian germ and somatic cells
    Kaoru Sato, Mikiko C. Siomi · 2020 · Proceedings of the Japan Academy Series B
  32. The role of noncoding RNAs in Parkinson’s disease: biomarkers and associations with pathogenic pathways
    Ming‐Che Kuo, Sam Chi-Hao Liu, Ya-Fang Hsu, Ruey‐Meei Wu · 2021 · Journal of Biomedical Science
  33. PIWI genes and piRNAs are ubiquitously expressed in mollusks and show patterns of lineage-specific adaptation
    Julia Jehn, Daniel Gebert, Frank Pipilescu, Sarah Stern, Julian Simon Thilo Kiefer, Charlotte Hewel, David Rosenkranz · 2018 · Communications Biology
  34. Functional specialization of Piwi proteins in Paramecium tetraurelia from post-transcriptional gene silencing to genome remodelling
    Khaled Bouhouche, Jean-François Goût, Aurélie Kapusta, Mireille Bétermier, Éric Meyer · 2011 · Nucleic Acids Research
  35. Population dynamics of PIWI-interacting RNAs (piRNAs) and their targets in Drosophila
    Jian Lü, Andrew G. Clark · 2009 · Genome Research
  36. Epigenetics: The Language of the Cell?
    Biao Huang, Cizhong Jiang, Rongxin Zhang · 2014 · Epigenomics
  37. Large Scale Full-Length cDNA Sequencing Reveals a Unique Genomic Landscape in a Lepidopteran Model Insect, Bombyx mori
    Yoshitaka Suetsugu, Ryo Futahashi, Hiroyuki Kanamori, Keiko Kadono‐Okuda, Shun-ichi Sasanuma, Junko Narukawa, Masahiro Ajimura, Akiya Jouraku, Nobukazu Namiki, Michihiko Shimomura et al. · 2013 · G3 Genes Genomes Genetics
  38. Antiviral Immunity and Virus-Mediated Antagonism in Disease Vector Mosquitoes
    Glady Hazitha Samuel, Zach N. Adelman, Kevin M. Myles · 2018 · Trends in Microbiology
  39. Alu and B1 Repeats Have Been Selectively Retained in the Upstream and Intronic Regions of Genes of Specific Functional Classes
    Aristotelis Tsirigos, Isidore Rigoutsos · 2009 · PLoS Computational Biology
  40. Epigenetics in radiation biology: a new research frontier
    Matt Merrifield, Olga Kovalchuk · 2013 · Frontiers in Genetics
  41. RNA-Interference Pathways Display High Rates of Adaptive Protein Evolution in Multiple Invertebrates
    William Hunt Palmer, Jarrod D. Hadfield, Darren J. Obbard · 2018 · Genetics
  42. The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers
    Zhang, Qun, Zhu, Yazhi, Cao, Xinyu, Tan, Wenhui, Yu, Jianglong, Lu, Yaqiong, Kang, Ran, Wang, Xiaolan, Li, Ermao · 2023 · Molecular Cancer
  43. Systematic and single cell analysis of Xenopus Piwi‐interacting RNAs and Xiwi
    Nelson C. Lau, Toshiro K. Ohsumi, Mark L. Borowsky, Robert E. Kingston, Michael D. Blower · 2009 · The EMBO Journal
  44. Exploring MicroRNA-Like Small RNAs in the Filamentous Fungus Fusarium oxysporum
    Rui Chen, Nan Jiang, Qiyan Jiang, Xianjun Sun, Yong Wang, Hui Zhang, Zheng Hu · 2014 · PLoS ONE
  45. Biological invasion: The influence of the hidden side of the (epi)genome
    Pierre Marin, Julien Genitoni, Dominique Barloy, Stéphane Maury, Patricia Gibert, Cameron K. Ghalambor, Cristina P Vieira · 2019 · Functional Ecology
  46. Role of Transposon-Derived Small RNAs in the Interplay between Genomes and Parasitic DNA in Rice
    Misuzu Nosaka‐Takahashi, Jun-Ichi Itoh, Yasuo Nagato, A. Ono, Aiko Ishiwata, Yutaka Sato · 2012 · PLoS Genetics
  47. Piwil2 Suppresses P53 by Inducing Phosphorylation of Signal Transducer and Activator of Transcription 3 in Tumor Cells
    Yilu Lu, Kun Zhang, Chao Li, Youlin Yao, Dachang Tao, Yunqiang Liu, Sizong Zhang, Yongxin Ma · 2012 · PLoS ONE
  48. Mechanisms of aphid adaptation to host plant resistance
    Ashley D. Yates, Andrew P. Michel · 2018 · Current Opinion in Insect Science
  49. Promoters Recognized by Forkhead Proteins Exist for Individual 21U-RNAs
    Germano Cecere, Grace X. Y. Zheng, Andrés Mansisidor, Katherine E. Klymko, Alla Grishok · 2012 · Molecular Cell
  50. PNLDC1, mouse pre‐piRNA Trimmer, is required for meiotic and post‐meiotic male germ cell development
    Toru Nishimura, Ippei Nagamori, Tsunetoshi Nakatani, Natsuko Izumi, Yukihide Tomari, Satomi Kuramochi‐Miyagawa, Toru Nakano · 2018 · EMBO Reports
  51. Gene Therapy for Neurodegenerative Diseases: Slowing Down the Ticking Clock
    Raygene Martier, Pavlina S. Konstantinova · 2020 · Frontiers in Neuroscience
  52. Developmental genome rearrangements in ciliates: a natural genomic subtraction mediated by non-coding transcripts
    Sandra Duharcourt, Gersende Lepère, Éric Meyer · 2009 · Trends in Genetics
  53. Ion trap collision-induced dissociation of multiply deprotonated RNA: c/y-ions versus (a-B)/w-ions
    Teng‐Yi Huang, Anastasia Kharlamova, Jian Liu, Scott A. McLuckey · 2008 · Journal of the American Society for Mass Spectrometry
  54. A Transcriptomic Analysis of Echinococcus granulosus Larval Stages: Implications for Parasite Biology and Host Adaptation
    John Parkinson, James D. Wasmuth, Gustavo Salinas, Cristiano Valim Bizarro, Chris Sanford, Matthew Berriman, Henrique Bunselmeyer Ferreira, Arnaldo Zaha, Mark Blaxter, Rick M. Maizels et al. · 2012 · PLoS neglected tropical diseases
  55. Inheritance of a Nuclear PIWI from Pluripotent Stem Cells by Somatic Descendants Ensures Differentiation by Silencing Transposons in Planarian
    Norito Shibata, Makoto Kashima, Taisuke Ishiko, Osamu Nishimura, Labib Rouhana, Kazuyo Misaki, Shigenobu Yonemura, Kuniaki Saito, Haruhiko Siomi, Mikiko C. Siomi et al. · 2016 · Developmental Cell
  56. Chapter 6 Drosophila Viruses and the Study of Antiviral Host‐Defense
    Tunde I. Huszar, Jean‐Luc Imler · 2008 · Advances in virus research
  57. Learning to live together: mutualism between self-splicing introns and their hosts
    David R. Edgell, Venkata R. Chalamcharla, Marlene Belfort · 2011 · BMC Biology
  58. Diversification of the Core RNA Interference Machinery in Chlamydomonas reinhardtii and the Role of DCL1 in Transposon Silencing
    J. Armando Casas-Mollano, Jennifer Rohr, Eun-Jeong Kim, Eniko Balassa, Karin van Dijk, Heriberto D. Cerutti · 2008 · Genetics
  59. Small RNAs Originated from Pseudogenes: cis- or trans-Acting?
    Xingyi Guo, Zhaolei Zhang, Mark Gerstein, Deyou Zheng · 2009 · PLoS Computational Biology
  60. Small RNA-based silencing strategies for transposons in the process of invading Drosophila species
    Nikolay V. Rozhkov, Alexei A. Aravin, Elena S. Zelentsova, Natalia G. Schostak, Ravi Sachidanandam, William Richard McCombie, Gregory J. Hannon, Michael B. Evgen’ev · 2010 · RNA
  61. Improving miRNA Delivery by Optimizing miRNA Expression Cassettes in Diverse Virus Vectors
    Elena Herrera-Carrillo, Ying Poi Liu, Ben Berkhout · 2017 · Human Gene Therapy Methods
  62. Multifaceted mammalian transcriptome
    Piero Carninci, Jun Yasuda, Yoshihide Hayashizaki · 2008 · Current Opinion in Cell Biology
  63. Non-coding RNA: a novel opportunity for the personalized treatment of multiple myeloma
    Nicola Amodio, Maria Teresa Di Martino, Antonino Neri, Pierosandro Tagliaferri, Pierfrancesco Tassone · 2013 · Expert Opinion on Biological Therapy
  64. Mobilizing diversity: transposable element insertions in genetic variation and disease
    Kathryn A. O’Donnell, Kathleen H. Burns · 2010 · Mobile DNA
  65. Ancient Endo-siRNA Pathways Reveal New Tricks
    Julie M. Claycomb · 2014 · Current Biology
  66. Transposable elements in natural populations of Drosophila melanogaster
    Yuh Chwen G. Lee, Charles H. Langley · 2010 · Philosophical Transactions of the Royal Society B Biological Sciences
  67. Small RNA expression and strain specificity in the rat
    Sam E.V. Linsen, Elzo de Wit, Ewart de Bruijn, Edwin P. J. G. Cuppen · 2010 · BMC Genomics
  68. Biological Mechanisms Determining the Success of RNA Interference in Insects
    Niels Wynant, Dulce Maria Metelo Fernandes dos Santos, Jozef Vanden Broeck · 2014 · International review of cytology
  69. Yb Integrates piRNA Intermediates and Processing Factors into Perinuclear Bodies to Enhance piRISC Assembly
    Yukiko Murota, Hirotsugu Ishizu, Shinichi Nakagawa, Yuka W. Iwasaki, Shinsuke Shibata, Miharu K. Kamatani, Kuniaki Saito, Hideyuki Okano, Haruhiko Siomi, Mikiko C. Siomi · 2014 · Cell Reports
  70. Dynamics of Transposable Element Invasions with piRNA Clusters
    Robert Kofler · 2019 · Molecular Biology and Evolution
  71. An atlas of gastric PIWI-interacting RNA transcriptomes and their utility for identifying signatures of gastric cancer recurrence
    Victor D. Martínez, Katey S.S. Enfield, David A. Rowbotham, Wan L. Lam · 2015 · Gastric Cancer
  72. Non-coding RNAs Function as Immune Regulators in Teleost Fish
    Man Wang, Shuai Jiang, Wei Wu, Fei Yu, Wenguang Chang, Peifeng Li, Kun Wang · 2018 · Frontiers in Immunology
  73. Hiwi Mediated Tumorigenesis Is Associated with DNA Hypermethylation
    Sara Siddiqi, Melissa Terry, Igor Matushansky · 2012 · PLoS ONE
  74. The plasticity of the mammalian transcriptome
    Johan Lindberg, Joakim Lundeberg · 2009 · Genomics
  75. Elements and machinery of non‐coding RNAs: toward their taxonomy
    Tetsuro Hirose, Yuichiro Mishima, Yukihide Tomari · 2014 · EMBO Reports
  76. Transposable elements in phytopathogenic Verticillium spp.: insights into genome evolution and inter- and intra-specific diversification
    Stefan G. Amyotte, Xiaoping Tan, Kayla K. Pennerman, María del Mar Jiménez-Gasco, Steven J. Klosterman, Li‐Jun Ma, Katherine F. Dobinson, Paola Veronese · 2012 · BMC Genomics
  77. Krimper Enforces an Antisense Bias on piRNA Pools by Binding AGO3 in the Drosophila Germline
    Kaoru Sato, Yuka W. Iwasaki, Aoi Shibuya, Piero Carninci, Yuuta Tsuchizawa, Hirotsugu Ishizu, Mikiko C. Siomi, Haruhiko Siomi · 2015 · Molecular Cell
  78. The long and short of inverted repeat genes in animals: MicroRNAs, mirtrons and hairpin RNAs
    Katsutomo Okamura, Wei‐Jen Chung, Eric C. Lai · 2008 · Cell Cycle
  79. LINE‐1 retrotransposons in healthy and diseased human brain
    Nicole A. Suarez, Ángela Macia, Alysson Renato Muotri · 2017 · Developmental Neurobiology
  80. Somatic Primary piRNA Biogenesis Driven by cis-Acting RNA Elements and trans-Acting Yb
    Hirotsugu Ishizu, Yuka W. Iwasaki, Shigeki Hirakata, Haruka Ozaki, Wataru Iwasaki, Haruhiko Siomi, Mikiko C. Siomi · 2015 · Cell Reports
  81. Sorting Out Small RNAs
    V. Narry Kim · 2008 · Cell
  82. Short non-coding RNA biology and neurodegenerative disorders: novel disease targets and therapeutics
    Marc S. Weinberg, Matthew J. A. Wood · 2009 · Human Molecular Genetics
  83. The Methyltransferase Activity of Clr4Suv39h Triggers RNAi Independently of Histone H3K9 Methylation
    Gerace, Erica L., Halic, Mario, Moazed, Danesh · 2010 · Molecular Cell
  84. Genetic Drift, Not Life History or RNAi, Determine Long-Term Evolution of Transposable Elements
    Amir Szitenberg, Soyeon Cha, Charles Opperman, David McK. Bird, Mark Blaxter, David H. Lunt · 2016 · Genome Biology and Evolution
  85. Noncoding RNAs: New regulatory code in chondrocyte apoptosis and autophagy
    Siyu Jiang, Yi Liu, Bilian Xu, Yan Zhang, Min Yang · 2020 · Wiley Interdisciplinary Reviews - RNA
  86. Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs
    Zuzana Loubalová, J. Fulka, Filip Horvat, Josef Pasulka, Radek Malı́k, Michiko Hirose, Atsuo Ogura, Petr Svoboda · 2021 · Nature Cell Biology
  87. New Insights into the Regulation of RNP Granule Assembly in Oocytes
    Jennifer A Schisa · 2012 · International review of cytology
  88. Meiosis genes in Daphnia pulexand the role of parthenogenesis in genome evolution
    Andrew Michael Schurko, John M. Logsdon Jr., Brian D. Eads · 2009 · BMC Evolutionary Biology
  89. Epigenetic reprogramming during vegetative phase change in maize
    Hong Li, Michael Freeling, Damon R. Lisch · 2010 · Proceedings of the National Academy of Sciences
  90. Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders
    Paola A. Spadaro, Timothy William Bredy · 2012 · Frontiers in Genetics
  91. Regulation of histone methylation by noncoding RNAs
    Richard Inho Joh, Christina M. Palmieri, Ian T. Hill, Mo Motamedi · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  92. Identification of piRNAs in Hela cells by massive parallel sequencing
    Yilu Lu, Chao Li, Kun Zhang, Huaqin Sun, Dachang Tao, Yunqiang Liu, Sizong Zhang, Yongxin Ma · 2010 · BMB Reports
  93. P53 and the defenses against genome instability caused by transposons and repetitive elements
    Arnold J. Levine, David Tsai Ting, Benjamin D. Greenbaum · 2016 · BioEssays
  94. Argonaute Proteins and Mechanisms of RNA Interference in Eukaryotes and Prokaryotes
    A. V. Olina, Andrey V. Kulbachinskiy, Alexei A. Aravin, Daria Esyunina · 2018 · Biochemistry (Moscow)
  95. Non-conflict theories for the evolution of genomic imprinting
    Hamish G. Spencer, Andrew G. Clark · 2014 · Heredity
  96. MicroRNAs and DNA methylation as epigenetic regulators of mitosis, meiosis and spermiogenesis
    Chencheng Yao, Yun Liu, Min Sun, Minghui Niu, Qingqing Yuan, Yanan Hai, Ying Guo, Zheng Chen, Jingmei Hou, Yang Liu et al. · 2015 · Reproduction
  97. New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing
    Alexander Maxwell Burroughs, Yoshinari Ando, L. Aravind · 2013 · Wiley Interdisciplinary Reviews - RNA
  98. Emerging roles for PIWI proteins in cancer
    Yi Tan, Lianyong Liu, Ming’an Liao, Chaobao Zhang, Shuanggang Hu, Zou Mei, Mingjun Gu, Xiangqi Li · 2015 · Acta Biochimica et Biophysica Sinica
  99. Genetic exchange in eukaryotes through horizontal transfer: connected by the mobilome
    Gabriel Luz Wallau, Cristina P Vieira, Élgion L. S. Loreto · 2018 · Mobile DNA
  100. Role of host tRNAs and aminoacyl-tRNA synthetases in retroviral replication
    Jin, Danni, Musier-Forsyth, Karin · 2019 · Journal of Biological Chemistry