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Cited by 2,667

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

Open access
Discher, Dennis E., Mooney, David J., Zandstra, Peter W.·2009·Science

Abstract

Stem cell fate is influenced by a number of factors and interactions that require robust control for safe and effective regeneration of functional tissue. Coordinated interactions with soluble factors, other cells, and extracellular matrices define a local biochemical and mechanical niche with complex and dynamic regulation that stem cells sense. Decellularized tissue matrices and synthetic polymer niches are being used in the clinic, and they are also beginning to clarify fundamental aspects of how stem cells contribute to homeostasis and repair, for example, at sites of fibrosis. Multifaceted technologies are increasingly required to produce and interrogate cells ex vivo, to build predictive models, and, ultimately, to enhance stem cell integration in vivo for therapeutic benefit.

Overview

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Integrity signals

Registry

Crossref · 10.1126/science.1171643

Cites

11 of 11 references verified0 citation errors · 0 not checkable

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Citations

Cites

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Metadata

Authors
Discher, D. E., Mooney, D. J., & Zandstra, P. W.
Venue
Science
Published
2009-06-26
Volume
324
Issue
5935
Pages
1673-1677
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2165673443
Cited by
2,667
References
11
FWCI
164.84
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Growth Factors, Matrices, and Forces Combine and Control Stem Cells. https://app.cochat.ai/papers/10.1126/science.1171643
The paper
Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009). Growth Factors, Matrices, and Forces Combine and Control Stem Cells. Science. https://doi.org/10.1126/science.1171643

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.