Mechanical forces direct stem cell behaviour in development and regeneration

Matrix elasticity directs stem cell lineage specification

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Role of YAP/TAZ in mechanotransduction

Dupont, S., Morsut, L., Aragona, M., Enzo, E., Giulitti, S., Cordenonsi, M., Zanconato, F., Le Digabel, J., Forcato, M., Bicciato, S., et al. (2011) · Nature · doi:10.1038/nature10137 · Cited by 5,979 · see citing works

Design, fabrication and control of soft robots

Rus, D., & Tolley, M. T. (2015) · Nature · doi:10.1038/nature14543 · Cited by 5,825 · see citing works

Reconstituting organ-level lung functions on a chip

Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250 · see citing works

Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

McBeath, R., Pirone, D. M., Nelson, C. M., Bhadriraju, K., & Chen, C. S. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00075-9 · Cited by 4,182 · see citing works

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009) · Science · doi:10.1126/science.1171643 · Cited by 2,666 · see citing works

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Chaudhuri, O., Gu, L., Klumpers, D., Darnell, M., Bencherif, S. A., Weaver, J. C., Huebsch, N., Lee, H.-P., Lippens, E., Duda, G. N., et al. (2016) · Nature Materials · doi:10.1038/nmat4489 · Cited by 2,443 · see citing works

Alginate hydrogels as synthetic extracellular matrix materials

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Nauli, S. M., Alenghat, F. J., Luo, Y., Williams, E., Vassilev, P., Li, X., Elia, A. E. H., Lu, W., Brown, E. M., Quinn, S. J., et al. (2003) · Nature Genetics · doi:10.1038/ng1076 · Cited by 2,057 · see citing works

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

Watanabe, K., Ueno, M., Kamiya, D., Nishiyama, A., Matsumura, M., Wataya, T., Takahashi, J. B., Nishikawa, S., Nishikawa, S.-I., Muguruma, K., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1310 · Cited by 2,055 · see citing works

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

Swift, J., Ivanovska, I. L., Buxboim, A., Harada, T., Dingal, P. C. D. P., Pinter, J., Pajerowski, J. D., Spinler, K. R., Shin, J., Tewari, M., et al. (2013) · Science · doi:10.1126/science.1240104 · Cited by 1,998 · see citing works

Geometric cues for directing the differentiation of mesenchymal stem cells

Kilian, K. A., Bugarija, B., Lahn, B. T., & Mrksich, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903269107 · Cited by 1,841 · see citing works

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

Gilbert, P. M., Havenstrite, K. L., Magnusson, K. E. G., Sacco, A., Leonardi, N. A., Kraft, P., Nguyen, N. K., Thrun, S., Lutolf, M. P., & Blau, H. M. (2010) · Science · doi:10.1126/science.1191035 · Cited by 1,587 · see citing works

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

Huebsch, N., Arany, P. R., Mao, A. S., Shvartsman, D. E., Ali, O. A., Bencherif, S. A., Rivera‐Feliciano, J., & Mooney, D. J. (2010) · Nature Materials · doi:10.1038/nmat2732 · Cited by 1,572 · see citing works

Extracellular-matrix tethering regulates stem-cell fate

Trappmann, B., Gautrot, J. E., Connelly, J. T., Strange, D. G. T., Li, Y., Oyen, M. L., Stuart, M. A. C., Boehm, H., Li, B., Viola Vogel, B., et al. (2012) · Nature Materials · doi:10.1038/nmat3339 · Cited by 1,570 · see citing works

Three-dimensional bioprinting of thick vascularized tissues

Kolesky, D. B., Homan, K. A., Skylar-Scott, M. A., & Lewis, J. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1521342113 · Cited by 1,492 · see citing works

Designer matrices for intestinal stem cell and organoid culture

Gjorevski, N., Sachs, N., Manfrin, A., Giger, S., Bragina, M. E., Ordóñez-Morán, P., Clevers, H., & Lutolf, M. P. (2016) · Nature · doi:10.1038/nature20168 · Cited by 1,426 · see citing works

Pulsed contractions of an actin–myosin network drive apical constriction

Martin, A. C., Kaschube, M., & Wieschaus, E. F. (2008) · Nature · doi:10.1038/nature07522 · Cited by 1,248 · see citing works

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

Khetan, S., Güvendiren, M., Legant, W. R., Cohen, D. M., Chen, C. S., & Burdick, J. A. (2013) · Nature Materials · doi:10.1038/nmat3586 · Cited by 1,171 · see citing works

Mechanical memory and dosing influence stem cell fate

Yang, C., Tibbitt, M. W., Basta, L. P., & Anseth, K. S. (2014) · Nature Materials · doi:10.1038/nmat3889 · Cited by 1,169 · see citing works

Reconstruction of Tissues by Dissociated Cells

Steinberg, M. S. (1963) · Science · doi:10.1126/science.141.3579.401 · Cited by 1,122 · see citing works

Substrate Modulus Directs Neural Stem Cell Behavior

Saha, K., Keung, A. J., Irwin, E. F., Li, Y., Little, L., Schaffer, D. V., & Healy, K. E. (2008) · Biophysical Journal · doi:10.1529/biophysj.108.132217 · Cited by 1,096 · see citing works

YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

Azzolin, L., Panciera, T., Soligo, S., Enzo, E., Bicciato, S., Dupont, S., Bresolin, S., Frasson, C., Basso, G., Guzzardo, V., et al. (2014) · Cell · doi:10.1016/j.cell.2014.06.013 · Cited by 1,094 · see citing works

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

Fu, J., Wang, Y.-K., Yang, M. T., Desai, R. A., Yu, X., Liu, Z., & Chen, C. S. (2010) · Nature Methods · doi:10.1038/nmeth.1487 · Cited by 1,073 · see citing works

Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation

Bertet, C., Sulak, L., & Lecuit, T. (2004) · Nature · doi:10.1038/nature02590 · Cited by 1,025 · see citing works

Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis

Hove, J. R., Köster, R. W., Forouhar, A. S., Acevedo‐Bolton, G., Fraser, S. E., & Gharib, M. (2003) · Nature · doi:10.1038/nature01282 · Cited by 1,000 · see citing works

Interplay of matrix stiffness and protein tethering in stem cell differentiation

Wen, J. H., Vincent, L. G., Fuhrmann, A., Choi, Y. S., Hribar, K. C., Taylor‐Weiner, H., Chen, S., & Engler, A. J. (2014) · Nature Materials · doi:10.1038/nmat4051 · Cited by 939 · see citing works

Soft biological materials and their impact on cell function

Levental, I., Georges, P. C., & Janmey, P. A. (2006) · Soft Matter · doi:10.1039/b610522j · Cited by 908 · see citing works

The relationship between force and focal complex development

Galbraith, C. G., Yamada, K. M., & Sheetz, M. P. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200204153 · Cited by 908 · see citing works

Substrate stress relaxation regulates cell spreading

Chaudhuri, O., Gu, L., Darnell, M., Klumpers, D. D., Bencherif, S. A., Weaver, J. C., Huebsch, N., & Mooney, D. J. (2015) · Nature Communications · doi:10.1038/ncomms7365 · Cited by 887 · see citing works

Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks

Griffin, D., Weaver, W., Scumpia, P. O., Carlo, D. D., & Segura, T. (2015) · Nature Materials · doi:10.1038/nmat4294 · Cited by 881 · see citing works

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

Benoit, D. S. W., Schwartz, M. P., Durney, A. R., & Anseth, K. S. (2008) · Nature Materials · doi:10.1038/nmat2269 · Cited by 825 · see citing works

Mechanotransduction in development: a growing role for contractility

Wozniak, M. A., & Chen, C. S. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2592 · Cited by 821 · see citing works

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

Chaudhuri, O., Koshy, S. T., Branco da Cunha, C., Shin, J.-W., Verbeke, C. S., Allison, K. H., & Mooney, D. J. (2014) · Nature Materials · doi:10.1038/nmat4009 · Cited by 820 · see citing works

Tensile forces govern germ-layer organization in zebrafish

Krieg, M., Arboleda-Estudillo, Y., Puech, P., Käfer, J., Graner, F., Müller, D. J., & Heisenberg, C. (2008) · Nature Cell Biology · doi:10.1038/ncb1705 · Cited by 804 · see citing works

Hydrodynamic stretching of single cells for large population mechanical phenotyping

Gossett, D. R., Tse, H. T. K., Lee, S. A., Ying, Y., Lindgren, A., Yang, O. O., Rao, J., Clark, A. T., & Carlo, D. D. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200107109 · Cited by 780 · see citing works

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

McMurray, R. J., Gadegaard, N., Tsimbouri, P. M., Burgess, K., McNamara, L. E., Tare, R. S., Murawski, K., Kingham, E., Oreffo, R. O. C., & Dalby, M. J. (2011) · Nature Materials · doi:10.1038/nmat3058 · Cited by 780 · see citing works

<i>In vivo</i> measurements of the elastic mechanical properties of human skin by indentation tests

Pailler-Mattei, C., Bec, S., & Zahouani, H. (2008) · Medical Engineering &amp; Physics · doi:10.1016/j.medengphy.2007.06.011 · Cited by 724 · see citing works

Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics

Guvendiren, M., & Burdick, J. A. (2012) · Nature Communications · doi:10.1038/ncomms1792 · Cited by 707 · see citing works

Determination of left–right patterning of the mouse embryo by artificial nodal flow

Nonaka, S., Shiratori, H., Saijoh, Y., & Hamada, H. (2002) · Nature · doi:10.1038/nature00849 · Cited by 683 · see citing works

Viscoelastic Retraction of Single Living Stress Fibers and Its Impact on Cell Shape, Cytoskeletal Organization, and Extracellular Matrix Mechanics

Kumar, S., Maxwell, I. Z., Heisterkamp, A., Polte, T. R., Lele, T. P., Salanga, M. C., Mazur, E., & Ingber, D. E. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.071506 · Cited by 681 · see citing works

Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL

Vartiainen, M., Guettler, S., Larijani, B., & Treisman, R. (2007) · Science · doi:10.1126/science.1141084 · Cited by 672 · see citing works

Controlling alginate gel degradation utilizing partial oxidation and bimodal molecular weight distribution

Boontheekul, T., Kong, H., & Mooney, D. J. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.044 · Cited by 659 · see citing works

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

Pathak, M. M., Nourse, J. L., Tran, T., Hwe, J., Arulmoli, J., Le, D. T. T., Bernardis, E., Flanagan, L. A., & Tombola, F. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1409802111 · Cited by 657 · see citing works

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

Fernández‐González, R., Simões, S. D. M., Röper, J.-C., Eaton, S., & Zallen, J. A. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.09.003 · Cited by 644 · see citing works

Transcription upregulation via force-induced direct stretching of chromatin

Tajik, A., Zhang, Y., Wei, F., Sun, J., Jia, Q., Zhou, W., Singh, R., Khanna, N., Belmont, A. S., & Wang, N. (2016) · Nature Materials · doi:10.1038/nmat4729 · Cited by 633 · see citing works

Collective cell durotaxis emerges from long-range intercellular force transmission

Sunyer, R., Conte, V., Escribano, J. M. G., Elósegui-Artola, A., Labernadie, A., Valon, L., Navajas, D., García‐Aznar, J. M., Muñoz, J. J., Roca‐Cusachs, P., et al. (2016) · Science · doi:10.1126/science.aaf7119 · Cited by 632 · see citing works

The minimal cadherin-catenin complex binds to actin filaments under force

Buckley, C. D., Tan, J., Anderson, K., Hanein, D., Volkmann, N., Weis, W. I., Nelson, W. J., & Dunn, A. R. (2014) · Science · doi:10.1126/science.1254211 · Cited by 629 · see citing works

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

Rauzi, M., Vérant, P., Lecuit, T., & Lenne, P. (2008) · Nature Cell Biology · doi:10.1038/ncb1798 · Cited by 616 · see citing works

Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells

Chowdhury, F., Na, S., Li, D., Poh, Y., Tanaka, T. S., Wang, F., & Wang, N. (2009) · Nature Materials · doi:10.1038/nmat2563 · Cited by 576 · see citing works

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

Baker, B. M., Trappmann, B., Wang, W. Y., Sakar, M. S., Kim, I. L., Shenoy, V. B., Burdick, J. A., & Chen, C. S. (2015) · Nature Materials · doi:10.1038/nmat4444 · Cited by 556 · see citing works

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure

Solon, J., Kaya-Çopur, A., Colombelli, J., & Brunner, D. (2009) · Cell · doi:10.1016/j.cell.2009.03.050 · Cited by 539 · see citing works

FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left–right determination

Tanaka, Y., Okada, Y., & Hirokawa, N. (2005) · Nature · doi:10.1038/nature03494 · Cited by 538 · see citing works

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

Trichet, L., Digabel, J. L., Hawkins, R. J., Vedula, S. R. K., Gupta, M., Ribrault, C., Hersen, P., Voituriez, R., & Ladoux, B. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1117810109 · Cited by 536 · see citing works

Biomechanical forces promote embryonic haematopoiesis

Adamo, L., Naveiras, O., Wenzel, P. L., McKinney‐Freeman, S., Mack, P. J., Gracia‐Sancho, J., Suchy‐Dicey, A. M., Yoshimoto, M., Lensch, M. W., Yöder, M. C., et al. (2009) · Nature · doi:10.1038/nature08073 · Cited by 534 · see citing works

A mechanosensitive transcriptional mechanism that controls angiogenesis

Mammoto, A., Connor, K. M., Mammoto, T., Yung, C. W., Huh, D., Aderman, C. M., Mostoslavsky, G., Smith, L. E. H., & Ingber, D. E. (2009) · Nature · doi:10.1038/nature07765 · Cited by 529 · see citing works

Periodontal Ligament Cells Under Mechanical Stress Induce Osteoclastogenesis by Receptor Activator of Nuclear Factor κB Ligand Up-Regulation via Prostaglandin E2 Synthesis

Kanzaki, H., Chiba, M., Shimizu, Y., & Mitani, H. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.2.210 · Cited by 527 · see citing works

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

Huebsch, N., Lippens, E., Lee, K., Mehta, M., Koshy, S. T., Darnell, M., Desai, R. M., Madl, C. M., Xu, M. M., Zhao, X., et al. (2015) · Nature Materials · doi:10.1038/nmat4407 · Cited by 525 · see citing works

Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo

Grill, S. W., Gönczy, P., Stelzer, E. H. K., & Hyman, A. A. (2001) · Nature · doi:10.1038/35054572 · Cited by 511 · see citing works

Mechanical stimulation improves tissue-engineered human skeletal muscle

Powell, C., Smiley, B. L., Mills, J., & Vandenburgh, H. H. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00595.2001 · Cited by 497 · see citing works

Germline Stem Cells Anchored by Adherens Junctions in the Drosophila Ovary Niches

Song, X., Zhu, C., Doan, C., & Xie, T. (2002) · Science · doi:10.1126/science.1069871 · Cited by 483 · see citing works

Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

Tse, J. R., & Engler, A. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015978 · Cited by 456 · see citing works

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

North, T. E., Goessling, W., Peeters, M. C. E., Li, P., Ceol, C. J., Lord, A. M., Weber, G. J., Harris, J. M., Cutting, C. C., Huang, P. L., et al. (2009) · Cell · doi:10.1016/j.cell.2009.04.023 · Cited by 446 · see citing works

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

Connelly, J. T., Gautrot, J. E., Trappmann, B., Tan, D. W., Donati, G., Huck, W. T. S., & Watt, F. M. (2010) · Nature Cell Biology · doi:10.1038/ncb2074 · Cited by 442 · see citing works

The influence of substrate creep on mesenchymal stem cell behaviour and phenotype

Cameron, A. R., Frith, J. E., & Cooper-White, J. J. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.04.003 · Cited by 428 · see citing works

In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation

Datta, N., Pham, Q. P., Sharma, U., Sikavitsas, V. I., Jansen, J. A., & Mikos, A. G. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505661103 · Cited by 411 · see citing works

Controlling cell–cell interactions using surface acoustic waves

Guo, F., Li, P., French, J. B., Mao, Z., Zhao, H., Li, S., Nama, N., Fick, J. R., Benkovic, S. J., & Huang, T. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1422068112 · Cited by 408 · see citing works

Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels

Das, R. K., Gocheva, V., Hammink, R., Zouani, O. F., & Rowan, A. E. (2015) · Nature Materials · doi:10.1038/nmat4483 · Cited by 407 · see citing works

Spatial organization within a niche as a determinant of stem-cell fate

Rompolas, P., Mesa, K. R., & Greco, V. (2013) · Nature · doi:10.1038/nature12602 · Cited by 398 · see citing works

Artificial niche microarrays for probing single stem cell fate in high throughput

Gobaa, S., Hoehnel, S., Roccio, M., Negro, A., Kobel, S., & Lutolf, M. P. (2011) · Nature Methods · doi:10.1038/nmeth.1732 · Cited by 390 · see citing works

Asymmetric division of contractile domains couples cell positioning and fate specification

Maître, J., Turlier, H., Illukkumbura, R., Eismann, B., Niwayama, R., Nédélec, F., & Hiiragi, T. (2016) · Nature · doi:10.1038/nature18958 · Cited by 381 · see citing works

Stress-relaxation behavior in gels with ionic and covalent crosslinks

Zhao, X., Huebsch, N., Mooney, D. J., & Suo, Z. (2010) · Journal of Applied Physics · doi:10.1063/1.3343265 · Cited by 375 · see citing works

Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery

Mao, A. S., Shin, J., Utech, S., Wang, H., Uzun, O., Li, W., Cooper, M. H., Hu, Y., Zhang, L., Weitz, D. A., et al. (2016) · Nature Materials · doi:10.1038/nmat4781 · Cited by 372 · see citing works

A cellular and regulatory map of the cholinergic nervous system of C. elegans

Pereira, L., Kratsios, P., Serrano-Saiz, E., Sheftel, H., Mayo, A. E., Hall, D. H., White, J. G., LeBoeuf, B., Garcia, L. R., Alon, U., et al. (2015) · eLife · doi:10.7554/elife.12432 · Cited by 365 · see citing works

Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro

Angele, P., Yoo, J. U., Smith, C., et al. (2003) · Journal of Orthopaedic Research® · doi:10.1016/s0736-0266(02)00230-9 · Cited by 361 · see citing works

Review of research on the mechanical properties of the human tooth

Zhang, Y.-R., Du, W., Zhou, X., & Yu, H. (2014) · International Journal of Oral Science · doi:10.1038/ijos.2014.21 · Cited by 358 · see citing works

Rigidity sensing and adaptation through regulation of integrin types

Elósegui-Artola, A., Bazellières, E., Allen, M. D., Andreu, I., Oria, R., Sunyer, R., Gomm, J. J., Marshall, J. F., Jones, J. L., Trepat, X., et al. (2014) · Nature Materials · doi:10.1038/nmat3960 · Cited by 358 · see citing works

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

Cosgrove, B. D., Mui, K. L., Driscoll, T. P., Caliari, S. R., Mehta, K. D., Assoian, R. K., Burdick, J. A., & Mauck, R. L. (2016) · Nature Materials · doi:10.1038/nmat4725 · Cited by 345 · see citing works

Differential effects of equiaxial and uniaxial strain on mesenchymal stem cells

Park, J. S., Chu, J. S. F., Cheng, C., Chen, F., Chen, D., & Li, S. (2004) · Biotechnology and Bioengineering · doi:10.1002/bit.20250 · Cited by 341 · see citing works

Massage Therapy Attenuates Inflammatory Signaling After Exercise-Induced Muscle Damage

Crane, J. D., Ogborn, D. I., Cupido, C., Melov, S., Hubbard, A., Bourgeois, J. M., & Tarnopolsky, M. A. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3002882 · Cited by 339 · see citing works

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

Nam, S., Hu, K. H., Butte, M. J., & Chaudhuri, O. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1523906113 · Cited by 336 · see citing works

MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells

Li, C. X., Talele, N. P., Boo, S., Koehler, A., Knee‐Walden, E. J., Balestrini, J. L., Speight, P., Kapùs, A., & Hinz, B. (2016) · Nature Materials · doi:10.1038/nmat4780 · Cited by 335 · see citing works

Tissue Deformation Modulates Twist Expression to Determine Anterior Midgut Differentiation in Drosophila Embryos

Desprat, N., Supatto, W., Pouille, P., Beaurepaire, E., & Farge, E. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.07.009 · Cited by 331 · see citing works

Matrix Stiffness and Nanoscale Spatial Organization of Cell-Adhesive Ligands Direct Stem Cell Fate

Ye, K., Wang, X., Cao, L., Li, S., Li, Z. H., Yu, L., & Ding, J. (2015) · Nano Letters · doi:10.1021/acs.nanolett.5b01619 · Cited by 328 · see citing works

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

Raab, M., Swift, J., Dingal, P. C. D. P., Shah, P., Shin, J., & Discher, D. E. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201205056 · Cited by 285 · see citing works

Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos

Colombo, K., Grill, S. W., Kimple, R. J., Willard, F. S., Siderovski, D. P., & Gönczy, P. (2003) · Science · doi:10.1126/science.1084146 · Cited by 285 · see citing works

Emergent cellular self-organization and mechanosensation initiate follicle pattern in the avian skin

Shyer, A. E., Rodrigues, A. R., Schroeder, G. G., Kassianidou, E., Kumar, S., & Harland, R. M. (2017) · Science · doi:10.1126/science.aai7868 · Cited by 283 · see citing works

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

Holst, J., Watson, S. L., Lord, M. S., Eamegdool, S. S., Bax, D. V., Nivison‐Smith, L., Kondyurin, A. V., Ma, L., Oberhauser, A. F., Weiss, A. S., et al. (2010) · Nature Biotechnology · doi:10.1038/nbt.1687 · Cited by 273 · see citing works

Defined three-dimensional microenvironments boost induction of pluripotency

Caiazzo, M., Okawa, Y., Ranga, A., Piersigilli, A., Tabata, Y., & Lutolf, M. P. (2016) · Nature Materials · doi:10.1038/nmat4536 · Cited by 271 · see citing works

The degree of mineralization is a determinant of bone strength: a study on human calcanei

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