Human Fatty Liver Disease: Old Questions and New Insights
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Items 301–400 of 1,007
- Emerging role of aging in the progression of NAFLD to HCCYongyuan He, Yinghong Su, Chengcheng Duan, Siyuan Wang, Wei Guo He, Yingting Zhang, Xiaofei An, Ming He · 2022 · Ageing Research Reviews
- Adverse Outcome Pathways and Drug-Induced Liver Injury TestingMathieu Vinken · 2015 · Chemical Research in Toxicology
- Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat FeedingNemanja U. Jovicic, Ilija D. Jeftic, Ivan Jovanović, Gordana D. Radosavljevic, Nebojša Arsenijević, Miodrag L. Lukić, Nada N. Pejnovic · 2015 · PLoS ONE
- High fat plus high cholesterol diet lead to hepatic steatosis in zebrafish larvae: a novel model for screening anti-hepatic steatosis drugsWencong Dai, Kunyuan Wang, Xinchun Zheng, Xiaohui Chen, Wenqing Zhang, Yiyue Zhang, Jinlin Hou, Li Liu · 2015 · Nutrition & Metabolism
- mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretionWilliam J. Quinn, Min Wan, Swapnil V. Shewale, Rebecca Gelfer, Daniel James Rader, Morris J. Birnbaum, Paul M. Titchenell · 2017 · Journal of Clinical Investigation
- Osteoprotegerin Promotes Liver Steatosis by Targeting the ERK–PPAR-γ–CD36 PathwayCheng Zhang, Xiaohe Luo, Jianrong Chen, Baoyong Zhou, Mengliu Yang, Rui Liu, Dongfang Liu, Harvest F. Gu, Zhiming Zhu, Hongting Zheng et al. · 2019 · Diabetes
- Gut-liver axis and fibrosis in nonalcoholic fatty liver disease: An input for novel therapiesOtilia Elena Frăsinariu, Sara Ceccarelli, Anna Alisi, Evelina Moraru, Valério Nobili · 2012 · Digestive and Liver Disease
- Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stressChandramohan Chitraju, Martin Trötzmüller, Jürgen Hartler, Heimo Wolinski, Gerhard Thallinger, Achim Lass, Rudolf Zechner, Robert Zimmermann, Harald C. Köfeler, Friedrich Spener · 2012 · Journal of Lipid Research
- Lycopene Metabolite, Apo-10′-Lycopenoic Acid, Inhibits Diethylnitrosamine-Initiated, High Fat Diet–Promoted Hepatic Inflammation and Tumorigenesis in MiceBlanche C. Ip, Kang‐Quan Hu, Chun Liu, Donald E. Smith, Martin S. Obin, Lynne M. Ausman, Xiangdong Wang · 2013 · Cancer Prevention Research
- Poria cocos polysaccharides rescue pyroptosis-driven gut vascular barrier disruption in order to alleviates non-alcoholic steatohepatitisHaixin Ye, Shuoyi Ma, Zhantu Qiu, Sha Huang, Guanghui Deng, Yunjia Li, Shu Xu, Menghan Yang, Hao Shi, Chaofeng Wu et al. · 2022 · Journal of Ethnopharmacology
- Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemiaPooja Jha, Thierry Claudel, Anna Baghdasaryan, Michaela Mueller, Emina Halilbasic, Suman Kumar Das, Achim Lass, Robert Zimmermann, Rudolf Zechner, Gerald Höefler et al. · 2013 · Hepatology
- Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cellsHonghui Guo, Guoling Liu, Ruimin Zhong, Yun Wang, Duan Wang, Min Xia · 2012 · Lipids in Health and Disease
- Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model SystemsRoss, Trenton T., Crowley, Collin, Kelly, Kenneth L., Rinaldi, Anthony, Beebe, David A., Lech, Matthew P., Martinez, Robert V., Carvajal-Gonzalez, Santos, Boucher, Magalie, Hirenallur-Shanthappa, Dinesh et al. · 2020 · Cellular and Molecular Gastroenterology and Hepatology
- MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J miceAlessandra Tessitore, Germana Cicciarelli, Filippo Del Vecchio, Agata Gaggiano, Daniela Verzella, Mariafausta Fischietti, Valentina Mastroiaco, Antonella Vetuschi, Roberta Sferra, Remo Barnabei et al. · 2016 · BMC Cancer
- The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesityJulien Bricambert, Marie‐Clotilde Alves‐Guerra, Pauline Estèves, Carina Prip‐Buus, Justine Bertrand‐Michel, Hervé Guillou, Christopher J. Chang, Mark N. Vander Wal, François Canonne‐Hergaux, Philippe Mathurin et al. · 2018 · Nature Communications
- Diet‐induced rodent models of obesity‐related metabolic disorders—A guide to a translational perspectiveInês Preguiça, André Alves, Sara Nunes, Rosa Fernandes, Pedro Gomes, Sofia Viana, Flávio Reis · 2020 · Obesity Reviews
- Cancer-Associated Fibroblasts in Hepatocellular Carcinoma and CholangiocarcinomaYing Fan, Mandy Sze Man Chan, Terence K. Lee · 2023 · Cellular and Molecular Gastroenterology and Hepatology
- Prolonged exposure to low-dose microcystin induces nonalcoholic steatohepatitis in mice: a systems toxicology studyJun He, Guangyu Li, Jun Chen, Juan Lin, Cheng Chu Zeng, Jing Chen, Junliang Deng, Ping Xie · 2016 · Archives of Toxicology
- IL-17 Axis Driven Inflammation in Non-Alcoholic Fatty Liver Disease ProgressionDaniel A. Giles, Maria E. Moreno‐Fernandez, Senad Divanovic · 2015 · Current Drug Targets
- Role of adipose tissue in methionine–choline-deficient model of non-alcoholic steatohepatitis (NASH)Pooja Jha, Astrid Knopf, Harald C. Köfeler, Michaela Mueller, Carolin Lackner, Gerald Höefler, Thierry Claudel, Michael Trauner · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid OxidationQian Gao, Yuzhi Jia, Gongshe Yang, Xiaohong Zhang, Prajwal Chaitanya Boddu, Bryon E. Petersen, Saiprasad Narsingam, Yi-Jun Zhu, Bayar Thimmapaya, Yashpal S. Kanwar et al. · 2015 · American Journal Of Pathology
- Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activationBing Zhou, Danli Zhou, Xiao‐Hong Wei, Rong-yu Zhong, Jie Xu, Liao Sun · 2017 · Acta Pharmacologica Sinica
- Targeting NAD+ in Metabolic Disease: New Insights Into an Old MoleculeYasir Elhassan, Andrew Philp, Gareth Geoffrey Lavery · 2017 · Journal of the Endocrine Society
- G0S2: A small giant controller of lipolysis and adipose-liver fatty acid fluxXiaodong Zhang, Bradlee L. Heckmann, Latoya E. Campbell, Jun Liu · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Metabolism: Insights into Health and DiseaseSébastien Molière, Amélie Jaulin, Catherine Tomasetto, Nassim Dali‐Youcef · 2023 · International Journal of Molecular Sciences
- Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systemsAlejandro Soto–Gutiérrez, Albert Gough, Lawrence A. Vernetti, D. Lansing Taylor, Satdarshan P. Monga · 2017 · Experimental Biology and Medicine
- Precision medicine in type 2 diabetesRashmi B. Prasad, Leif Groop · 2018 · Journal of Internal Medicine
- Bifidobacterium-derived short-chain fatty acids and indole compounds attenuate nonalcoholic fatty liver disease by modulating gut-liver axisSang Jun Yoon, Jeong Seok Yu, Byeong Hyun Min, Haripriya Gupta, Sung‐Min Won, Hyojin Park, Sang Hak Han, Byung‐Yong Kim, Kyung Hwan Kim, Byoung Kook Kim et al. · 2023 · Frontiers in Microbiology
- Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathwaysChunxiao Li, Jianguo Gao, Xingyong Wan, Yi Chen, Chengfu Xu, Zemin Feng, Hang Zeng, Yiming Lin, Han Ma, Ping Xu et al. · 2019 · World Journal of Gastroenterology
- Liver Physiology: Metabolism and DetoxificationJohn Y.L. Chiang · 2014 · Elsevier eBooks
- Increased expression of c-Jun in nonalcoholic fatty liver diseaseChristoph Dorn, Julia C. Engelmann, M Saugspier, A. Koch, Arndt Hartmann, Martina Müller, Rainer Spang, Anja‐Katrin Bosserhoff, Claus Hellerbrand · 2014 · Laboratory Investigation
- Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic SteatohepatitisKento Imajo, Masato Yoneda, Takaomi Kessoku, Yuji Ogawa, Shin Maeda, Yoshio Sumida, Hideyuki Hyogo, Yuichiro Eguchi, Koichiro Wada, Atsushi Nakajima · 2013 · International Journal of Molecular Sciences
- Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin ResistancePär Steneberg, Alexandros G. Sykaras, Fredrik Backlund, Jurate Straseviçiene, Ingegerd Söderström, Helena Edlund · 2015 · Journal of Biological Chemistry
- Aurone Derivative Revealing the Metabolism of Lipid Droplets and Monitoring Oxidative Stress in Living CellsKang‐Nan Wang, Shuyue Ma, Yanyan Ma, Yuping Zhao, Miaomiao Xing, Liyu Zhou, Duxia Cao, Weiying Lin · 2020 · Analytical Chemistry
- Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver diseaseAnping Chen, Youcai Tang, Victoria R. Davis, Fong‐Fu Hsu, Susan Kennedy, Haowei Song, JOHN W. TURK, Elizabeth M. Brunt, Elizabeth P. Newberry, Nicholas O. Davidson · 2013 · Hepatology
- Melatonin improves non-alcoholic fatty liver disease via MAPK-JNK/P38 signaling in high-fat-diet-induced obese miceHang Sun, Xingchun Wang, Jiaqi Chen, Kexiu Song, Aaron M. Gusdon, Liang Li, Le Bu, Shen Qu · 2016 · Lipids in Health and Disease
- Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistanceElaine Xu, Mafalda M. A. Pereira, Ismene Karakasilioti, Sebastian Theurich, Mona Al-Maarri, Gunter Rappl, Ari Waisman, Frank Thomas Wunderlich, Jens C. Brüning · 2017 · Nature Communications
- Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent PathwaysDebra Dorotea, Daisuke Koya, Hunjoo Ha · 2020 · Frontiers in Pharmacology
- Yin Yang 1 facilitates hepatocellular carcinoma cell lipid metabolism and tumor progression by inhibiting PGC-1β-induced fatty acid oxidationYanjun Li, Vivi Kasim, Xuesong Yan, Lang Li, Ian Timothy Sembiring Meliala, Can Huang, Zhuolin Li, Ke Lei, Guanbin Song, Xiaodong Zheng et al. · 2019 · Theranostics
- The metabolic basis of nonalcoholic steatohepatitisManu V. Chakravarthy, Brent A. Neuschwander‐Tetri · 2020 · Endocrinology Diabetes & Metabolism
- Peroxisome proliferator-activated receptor-γ as a therapeutic target for hepatic fibrosis: from bench to bedsideFeng Zhang, Desong Kong, Yin Lu, Shizhong Zheng · 2012 · Cellular and Molecular Life Sciences
- PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysisJulia Perttilä, Carolina Huaman Samanez, Sandrine Caron, Kimmo Tanhuanpää, Bart Staels, Hannele Yki‐Järvinen, Vesa M. Olkkonen · 2012 · American Journal of Physiology-Endocrinology and Metabolism
- Specialized Cortex Glial Cells Accumulate Lipid Droplets in Drosophila melanogasterViktor Kis, Benjámin Barti, Mónika Lippai, Miklós Sass · 2015 · PLoS ONE
- Nonalcoholic Fatty Liver Disease, Nocturnal Hypoxia, and Endothelial Function in Patients With Sleep ApneaCaroline Minville, Marie‐Noëlle Hilleret, Renaud Tamisier, Judith Aron‐Wisnewsky, Karine Clément, Candice Trocmé, Jean‐Christian Borel, Patrick A. Levy, Jean‐Pierre Zarski, Jean‐Louis Pépin · 2013 · CHEST Journal
- Endoplasmic reticulum stress related molecular mechanisms in nonalcoholic steatohepatitisPerinur Bozaykut, Ali Şahin, Betul Karademir-Yilmaz, Nesrin Kartal Özer · 2016 · Mechanisms of Ageing and Development
- The lipid droplet: A conserved cellular organelleCongyan Zhang, Pingsheng Liu · 2017 · Protein & Cell
- Berberine alleviates nonalcoholic fatty liver induced by a high‐fat diet in mice by activating SIRT3Xi Xu, Xiaopeng Zhu, Jinyun Bai, Pu Xia, Yu Li, Yan Lü, Xiao-Ying Li, Xin Gao · 2019 · The FASEB Journal
- C/EBP Homologous Protein-induced Macrophage Apoptosis Protects Mice from SteatohepatitisHarmeet Malhi, Erin M. Kropp, Vinna Clavo, Christina R. Kobrossi, JaeSeok Han, Amy S. Mauer, Jing Yong, Randal J. Kaufman · 2013 · Journal of Biological Chemistry
- Gut microbiota, fatty liver disease, and hepatocellular carcinomaChu, Huikuan, Williams, Brandon, Schnabl, Bernd · 2018 · Liver Research
- Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosisShin‐Yu Tsai, Pei-Chin Chung, Eddy Owaga, I-Jong Tsai, Pei-Yuan Wang, Jeng‐I Tsai, Tien-Shun Yeh, Rong‐Hong Hsieh · 2016 · Nutrition & Metabolism
- Evaluation of Polygenic Determinants of Non-Alcoholic Fatty Liver Disease (NAFLD) By a Candidate Genes Resequencing StrategyAlessia Di Costanzo, Francesca Belardinilli, Diego Bailetti, Marialuisa Sponziello, Laura D’Erasmo, Licia Polimeni, Francesco Baratta, Daniele Pastori, Fabrizio Ceci, Anna Montali et al. · 2018 · Scientific Reports
- Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in miceBo Xia, Guo He Cai, Hao Yang, Shu Pei Wang, Grant A. Mitchell, Jiang Wei Wu · 2017 · PLoS Genetics
- Metabolic profiling of visceral adipose tissue from obese subjects with or without metabolic syndromeEleonora Candi, Manfredi Tesauro, Carmine Cardillo, Anna Maria Lena, Francesca Schinzari, Giuseppe Rodia, Giuseppe Sigismondo Sica, Paolo Gentileschi, Valentina Rovella, Margherita Annicchiarico‐Petruzzelli et al. · 2018 · Biochemical Journal
- Systematic Review with Meta-Analysis: The Effects of Probiotics in Nonalcoholic Fatty Liver DiseaseMeng-Wei Xiao, Shixin Lin, Zhaohua Shen, Weiwei Luo, Xiaoyan Wang · 2019 · Gastroenterology Research and Practice
- Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and InflammationKira L. Diehl, Julia Vorac, Kristina Hofmann, Philippa Meiser, Iris A. Unterweger, Lars Kuerschner, Heike Weighardt, Irmgard Förster, Christoph Thiele · 2020 · Cells
- Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in miceClaudia Daniela Fuchs, Thierry Claudel, Pooja Kumari, Guenter Haemmerle, Marion Julia Pollheimer, Tatjana Stojaković, Hubert Scharnagl, Emina Halilbasic, Judith Gumhold, Dagmar Silbert et al. · 2012 · Hepatology
- Hepatic Mitogen-Activated Protein Kinase Phosphatase 1 Selectively Regulates Glucose Metabolism and Energy HomeostasisAhmed Lawan, Lei Zhang, Florian Gatzke, Kisuk Min, Michael J. Jurczak, Mashael Al‐Mutairi, Patric Richter, João Paulo Camporez, Anthony D. Couvillon, Dominik Hans Pesta et al. · 2014 · Molecular and Cellular Biology
- A Nutrigenomic Approach to Non-Alcoholic Fatty Liver DiseasePaola Dongiovanni, Luca V. C. Valenti · 2017 · International Journal of Molecular Sciences
- Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: Risk and prognosis predictionManal M. Hassan, Ahmed Omar Kaseb, Carol Jean Etzel, Hashem B. El‐Serag, Margaret R. Spitz, Ping Chang, Katherine Stemke‐Hale, Mei Liu, Asif Rashid, Mohamed Shama et al. · 2013 · Molecular Carcinogenesis
- Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLDClaudia Daniela Fuchs, Thierry Claudel, Michael Trauner · 2014 · Trends in Endocrinology and Metabolism
- Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)Shao, Wei, Espenshade, Peter J. · 2014 · Journal of Biological Chemistry
- Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolismBenoît Bilanges, Samira Alliouachene, Wayne P Pearce, Daniele Morelli, György Szabadkai, Yuen-Li Chung, Gaëtan Chicanne, Colin Valet, Julia M. Hill, Peter J. Voshol et al. · 2017 · Nature Communications
- Imbalanced insulin action in chronic over nutrition: Clinical harm, molecular mechanisms, and a way forwardKevin Jon Williams, Xiangdong Wu · 2016 · Atherosclerosis
- The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humansAndreas Peter, Markéta Kovářová, Harald Staiger, Jürgen Machann, Fritz Schick, Alfred Königsrainer, Ingmar Königsrainer, Erwin D. Schleicher, Andreas Fritsche, Hans‐Ulrich Häring et al. · 2017 · American Journal of Physiology-Endocrinology and Metabolism
- Association Between Dietary Fiber Intake and Non-alcoholic Fatty Liver Disease in AdultsHuimin Zhao, Aihua Yang, Lina Mao, Yaning Quan, Jiajia Cui, Yongye Sun · 2020 · Frontiers in Nutrition
- Diet-Sensitive Sources of Reactive Oxygen Species in Liver Mitochondria: Role of Very Long Chain Acyl-CoA DehydrogenasesAriel R. Cardoso, Pâmela A. Kakimoto, Alicia Juliana Kowaltowski · 2013 · PLoS ONE
- Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridemic patientsMiao Hu, Chiu‐Wing Winnie Chu, Shizuya Yamashita, David Ka Wai Yeung, Lin Shi, Defeng Wang, Daisaku Masuda, Ya‐Ling Yang, Brian Tomlinson · 2012 · Journal of Lipid Research
- Activation of aryl hydrocarbon receptor dissociates fatty liver from insulin resistance by inducing fibroblast growth factor 21Peipei Lu, Jiong Yan, Ke Liu, Wojciech G. Garbacz, Pengcheng Wang, Meishu Xu, Xiaochao Ma, Wen Xie · 2015 · Hepatology
- A Novel APOB Mutation Identified by Exome Sequencing Cosegregates With Steatosis, Liver Cancer, and HypocholesterolemiaAngelo Baldassare Cefalu, James P. Pirruccello, Davide Noto, Stacey Gabriel, Vincenza Valenti, Namrata Gupta, Rossella Spina, Patrizia Tarugi, Sekar Kathiresan, Maurizio Rocco Averna · 2013 · Arteriosclerosis Thrombosis and Vascular Biology
- PNPLA3 expression and its impact on the liver: current perspectivesBruschi, Francesca Virginia, Tardelli, Matteo, Claudel, Thierry, Trauner, Michael · 2017 · Hepatic Medicine: Evidence and Research
- Nonalcoholic fatty liver disease stratification by liver lipidomicsOlga Vvedenskaya, Tim Daniel Rose, Oskar L. Knittelfelder, Alessandra Palladini, Judith A. H. Wodke, Kai Schuhmann, Jacobo Miranda Ackerman, Yuting Wang, Canan Has, Mario Brosch et al. · 2021 · Journal of Lipid Research
- AASLD Practice Statement on the evaluation and management of metabolic dysfunction–associated steatotic liver disease in childrenStavra A. Xanthakos, Samar H. Ibrahim, Kathryn Harlow Adams, Rohit Kohli, Pushpa Sathya, Shikha S. Sundaram, Miriam B. Vos, Ashish Dhawan, Sonia Caprio, Cynthia A. Behling et al. · 2025 · Hepatology
- The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver diseaseErin K. Daugherity, Gabriel Balmus, Ahmed Al Saei, Elizabeth S. Moore, Delbert S. Abi Abdallah, Arlin B. Rogers, Robert S. Weiss, Kirk J. Maurer · 2012 · Cell Cycle
- Potential for Dietary ω-3 Fatty Acids to Prevent Nonalcoholic Fatty Liver Disease and Reduce the Risk of Primary Liver CancerDonald Β. Jump, Christopher M. Depner, Sasmita Tripathy, Kelli A. Lytle · 2015 · Advances in Nutrition
- Role of folate in nonalcoholic fatty liver diseaseVictoria Sid, Yaw Loong Siow, O Karmin · 2017 · Canadian Journal of Physiology and Pharmacology
- Metabolic insights from zebrafish genetics, physiology, and chemical biologyAmnon Schlegel, Philipp Gut · 2015 · Cellular and Molecular Life Sciences
- Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progressionDoris Kaltenecker, Madeleine Themanns, Kristina M. Mueller, Katrin Spirk, Tobias Suske, Olaf Merkel, Lukas Kenner, Andreia Luís, Andrey V. Kozlov, Johannes Haybaeck et al. · 2018 · Cytokine
- Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3AYoung-Chae Kim, Sunmi Seok, Yang Zhang, Jian Ma, B. Kong, Grace L. Guo, B. Kemper, J. Kemper · 2020 · Nature Communications
- The role of angiotensin II in nonalcoholic steatohepatitisE. Matthew Morris, Justin A. Fletcher, John P. Thyfault, R. Scott Rector · 2012 · Molecular and Cellular Endocrinology
- Interaction of volatile organic compounds and underlying liver disease: a new paradigm for riskAnna L. Lang, Juliane I. Beier · 2018 · Biological Chemistry
- PNPLA3 as a therapeutic target for fatty liver disease: the evidence to dateCherubini, Alessandro, Casirati, Elia, Tomasi, Melissa, Valenti, Luca · 2021 · Expert Opinion on Therapeutic Targets
- Open Chromatin Profiling in Mice Livers Reveals Unique Chromatin Variations Induced by High Fat DietAmy Leung, Brian W. Parks, Juan Du, Candi Trac, Ryan L. Setten, Yin Chen, Kevin Brown, Aldons Jake Lusis, Rama D Natarajan, Dustin E. Schones · 2014 · Journal of Biological Chemistry
- Preventive Efficiency of Green Tea and Its Components on Nonalcoholic Fatty Liver DiseaseJie Zhou, Chi‐Tang Ho, Piaopiao Long, Qilu Meng, Liang Zhang, Xiaochun Wan · 2019 · Journal of Agricultural and Food Chemistry
- Applications of human organoids in the personalized treatment for digestive diseasesQinying Wang, Fanying Guo, Yutao Jin, Yanlei Ma · 2022 · Signal Transduction and Targeted Therapy
- Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic miceLipeng Bi, John Y.L. Chiang, Wen‐Xing Ding, Winston Dunn, Benjamin Roberts, Tiangang Li · 2013 · Journal of Lipid Research
- TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in miceShiming Jiang, Lindsey Cauthen Minter, Sabrina A. Stratton, Peirong Yang, Hussein A. Abbas, Zeynep Coban‐Akdemir, Vinod Pant, Sean M. Post, Mihai Gagea, Richard G. Lee et al. · 2014 · Journal of Hepatology
- Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver diseaseSokrates Stein, Vera Lemos, Pan Xu, Hadrien Demagny, Xu Wang, Dongryeol Ryu, Verónica Jiménez, Fátima Bosch, Thomas Felix Lüscher, Maaike H. Oosterveer et al. · 2017 · Journal of Clinical Investigation
- Catalase and nonalcoholic fatty liver diseaseSu‐Kyung Shin, Hyun-Woo Cho, Seung-Eun Song, Dae‐Kyu Song · 2018 · Pflügers Archiv - European Journal of Physiology
- FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activationJun Yao · 2014 · World Journal of Gastroenterology
- Maraviroc, a CCR5 antagonist, ameliorates the development of hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD)Laura Pérez‐Martínez, Patricia Pérez‐Matute, Javier Aguilera‐Lizarraga, Susana Rubio-Mediavilla, Judit Narro-Íñiguez, Emma Recio, Laura Ochoa‐Callejero, José Antonio Oteo, José Ramón Blanco · 2014 · Journal of Antimicrobial Chemotherapy
- CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular CarcinomaZhao‐Qing Shen, Yi‐Fan Chen, Jim-Ray Chen, Yuh‐Shan Jou, Pei-Chun Wu, Cheng‐Heng Kao, Chih‐Hao Wang, Yi‐Long Huang, Chian‐Feng Chen, Ting Huang et al. · 2017 · Cell Reports
- Disruption of adenosine 2A receptor exacerbates NAFLD through increasing inflammatory responses and SREBP1c activityYuli Cai, Honggui Li, Mengyang Liu, Ya Pei, Juan Zheng, Jing Zhou, Xianjun Luo, Wenya Huang, Linqiang Ma, Qiuhua Yang et al. · 2018 · Hepatology
- Recent advances in dietary supplementation, in treating non-alcoholic fatty liver diseaseTannaz Eslamparast · 2014 · World Journal of Hepatology
- Bile Acid Signaling in Metabolic and Inflammatory Diseases and Drug DevelopmentTiangang Li, John Y.L. Chiang · 2024 · Pharmacological Reviews
- Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patientsXiaoli Pan, Pei Wang, Jinzhuo Luo, Zhijun Wang, Yuhu Song, Jin Ye, Xiaohua Hou · 2014 · Endocrine
- Systematic review of bariatric surgery liver biopsies clarifies the natural history of liver disease in patients with severe obesityPierre Bédossa, Joan Tordjman, Judith Aron‐Wisnewsky, Christine Poitou, Jean‐Michel Oppert, Adriana Torcivia, Jean‐Luc Bouillot, Valérie Paradis, Vlad Ratziu, Karine Clément · 2016 · Gut
- Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation of SIRT3/AMPK/ACC PathwayYupei Zhang, Yuanjun Deng, Kairui Tang, Run-sen Chen, Liang Shu, Yinji Liang, Han Li, Ling Jin, Zien Liang, Yan‐Ning Chen et al. · 2019 · Current Medical Science
- Long-term bisphenol S exposure aggravates non-alcoholic fatty liver by regulating lipid metabolism and inducing endoplasmic reticulum stress response with activation of unfolded protein response in male zebrafishJingyu Qin, Shaoguo Ru, Weiwei Wang, Liping Hao, Yiran Ru, Jun Wang, Xiaona Zhang · 2020 · Environmental Pollution
- Dietary Ferulic Acid Supplementation Improves Antioxidant Capacity and Lipid Metabolism in Weaned PigletsYouxia Wang, Xiaoling Chen, Zhiqing Huang, Daiwen Chen, Bing Yu, Jie Yu, Hong Chen, Jun He, Yuheng Luo, Ping Zheng · 2020 · Nutrients
- Modeling PNPLA3‐Associated NAFLD Using Human‐Induced Pluripotent Stem CellsSamantha Grace Tilson, Carola Maria Morell, An‐Sofie Lenaerts, Seung Bum Park, Zongyi Hu, Benjamin Jenkins, Albert Koulman, T. Jake Liang, Ludovic Vallier · 2021 · Hepatology