The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release
Open accessAbstract
Reconstituting Synaptic Vesicle Fusion: Membrane fusion reactions have been reconstituted in vitro, but often the reconstituted reactions have not directly mirrored the requirements for synaptic vesicle fusion in vivo. Previous work generally used only N -ethylmaleimide–sensitive factor (NSF) attachment protein SNAP receptors (SNAREs) and one or two additional components and could not explain why deletion of Munc18-1 or Munc13 abolishes neurotransmitter release completely, yielding the severe disruptions of synaptic vesicle release in knockout mouse. Ma et al. (p. 421 , published online 20 December; see the Perspective by Hughson ) now present a faithful reconstitution of synaptic vesicle fusion. Membrane fusion required Munc18-1 and Munc13 when the reconstitution experiments included all eight key components (three SNAREs, Munc18-1, Munc13, synaptotagmin-1, NSF, and α-SNAP).
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Cites
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
Sutton, R. B., Fasshauer, D., Jahn, R., & Brunger, A. T. (1998) · Nature · doi:10.1038/26412 · Cited by 2,417
Membrane Fusion: Grappling with SNARE and SM Proteins
Südhof, T. C., & Rothman, J. E. (2009) · Science · doi:10.1126/science.1161748 · Cited by 2,027
Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex
Ma, C., Li, W., Xu, Y., & Rizo, J. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2047 · Cited by 363
Self-citationAraç, D., Chen, X., Khant, H. A., Ubach, J., Ludtke, S. J., Kikkawa, M., Johnson, A. E., Chiu, W., Südhof, T. C., & Rizo, J. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1056 · Cited by 256
Self-citationMunc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis
Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D. R., Pang, Z. P., Wojcik, S. M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1758 · Cited by 243
Self-citationSynaptic proteins promote calcium-triggered fast transition from point contact to full fusion
Diao, J., Grob, P., Cipriano, D. J., Kyoung, M., Zhang, Y., Shah, S., Nguyen, A., Padolina, M., Srivastava, A., Vrljic, M., et al. (2012) · eLife · doi:10.7554/elife.00109 · Cited by 170
The Janus-faced nature of the C2B domain is fundamental for synaptotagmin-1 function
Xue, M., Ma, C., Craig, T. K., Rosenmund, C., & Rizo, J. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1508 · Cited by 131
Self-citationDynamic Ca 2+ -Dependent Stimulation of Vesicle Fusion by Membrane-Anchored Synaptotagmin 1
Lee, H.-K., Yang, Y., Su, Z., Hyeon, C., Lee, T.-S., Lee, H.-W., Kweon, D.-H., Shin, Y.-K., & Yoon, T.-Y. (2010) · Science · doi:10.1126/science.1187722 · Cited by 123
Cited by
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
Südhof, T. C. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.022 · Cited by 1,197
The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17
Jiang, P., Nishimura, T., Sakamaki, Y., Itakura, E., Hatta, T., Natsume, T., & Mizushima, N. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-08-0447 · Cited by 501
The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones
Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T. C., Rhee, J., Brose, N., & Cooper, B. H. (2014) · Neuron · doi:10.1016/j.neuron.2014.10.009 · Cited by 389
The Synaptic Vesicle Release Machinery
Rizo, J., & Xu, J. (2015) · Annual Review of Biophysics · doi:10.1146/annurev-biophys-060414-034057 · Cited by 339
Self-citationSynaptic vesicle recycling: steps and principles
Rizzoli, S. O. (2014) · The EMBO Journal · doi:10.1002/embj.201386357 · Cited by 317
Metadata
- Authors
- Ma, C., Su, L., Seven, A. B., Xu, Y., & Rizo, J.
- Venue
- Science
- Published
- 2013-01-25
- Volume
- 339
- Issue
- 6118
- Pages
- 421-425
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2101097180
- Cited by
- 409
- References
- 8
- FWCI
- 13.97
- Type
- journal article
- Language
- en
- Open access
- green
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