Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

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    Natascha Hermann‐Kleiter, Gottfried Baier · 2014 · Cell Communication and Signaling
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    Emma M. Quinn, Ciara Coleman, Ben Molloy, Patricia Domínguez Castro, Paul Cormican, Valerie Trimble, Nasir Uddin Mahmud, Ross McManus · 2015 · PLoS ONE
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    Derek E. Kelly, Matthew E.B. Hansen, Sarah A. Tishkoff · 2017 · Current Opinion in Systems Biology
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    Francesca Salani, Valentina Sterbini, Eleonora Sacchinelli, Mariagrazia Garramone, Paola Bossù · 2019 · Frontiers in Immunology
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    Kátia de Paiva Lopes, Lei Yu, Xianli Shen, Yiguo Qiu, Shinya Tasaki, Artemis Iatrou, Michal Schnaider Beeri, Nicholas T. Seyfried, Vilas Menon, Yanling Wang et al. · 2023 · Alzheimer s & Dementia
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    Jack Humphrey, Erica Brophy, Roman Kosoy, Biao Zeng, Elena Coccia, Daniele Mattei, Ashvin Ravi, Tatsuhiko Naito, Anastasia G. Efthymiou, Elisa Navarro et al. · 2025 · Nature Genetics
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    Robert Yang, Jie Quan, Reza Sodaei, François Aguet, Ayellet V. Segrè, John Allen, Thomas A. Lanz, Veronica Reinhart, Matthew E. Crawford, Samuel A. Hasson et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
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    Casey E. Romanoski, Verena M. Link, Sven Heinz, Christopher K. Glass · 2015 · Trends in Immunology
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    Mulin Jun Li, Zipeng Liu, Zipeng Liu, Bin Yan, Zhicheng Pan, Dandan Huang, Qian Liang, Dingge Ying, Feng Xu, Hongcheng Yao et al. · 2017 · Genome biology
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    Yongfei Wang, Yan Zhang, Zhengwei Zhu, Ting-You Wang, David Lester Morris, Jiangshan Jane Shen, Huoru Zhang, Hai‐Feng Pan, Jing Yang, Sen Yang et al. · 2018 · Annals of the Rheumatic Diseases
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    Bryant Lim, Ioannis Prassas, Eleftherios P. Diamandis · 2020 · The Journal of Applied Laboratory Medicine
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    Yan Zhang, Jing Yang, Jing Zhang, Liangdan Sun, Nattiya Hirankarn, Hai‐Feng Pan, Chak Sing Lau, Tak Mao Chan, Tsz Leung Lee, Alexander Moon Ho Leung et al. · 2015 · Annals of the Rheumatic Diseases
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    Kayhan N. Batmanghelich, Adrian Vasile Dalca, Gerald Quon, Mert Rory Sabuncu, Polina Golland · 2016 · IEEE Transactions on Medical Imaging
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    Biljana Atanasovska, Vinod Kumar, Jingyuan Fu, Cisca Wijmenga, Marten H. Hofker · 2015 · Trends in Endocrinology and Metabolism
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    Yan Ge, PATRICK J. CONCANNON · 2018 · European Journal of Human Genetics
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    Janet C Harwood, Ganna Leonenko, Rebecca Sims, Valentina Escott‐Price, Julie H. Williams, Peter Holmans · 2021 · Brain Communications
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    Paul Martin, Amanda McGovern, Jonathan Massey, Stefan Schoenfelder, Kate Duffus, Annie Yarwood, Anne C Barton, Jane Worthington, Peter Fraser, Stephen Eyre et al. · 2016 · PLoS ONE
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    Patrick, Ellis, Olah, Marta, Taga, Mariko, Klein, Hans-Ulrich, Xu, Jishu, White, Charles C., Felsky, Daniel, Agrawal, Sonal, Gaiteri, Chris, Chibnik, Lori B. et al. · 2021 · Translational Psychiatry
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    Alex Lewin, Habib Saadi, James E. Peters, Aida Moreno‐Moral, James Christopher Lee, Kenneth G. C. Smith, Enrico G. Petretto, Leonardo Bottolo, Sylvia T. Richardson · 2015 · Bioinformatics
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    Allison L. Richards, Donovan Watza, Anthony S Findley, Adnan Alazizi, Xiaoquan Wen, Athma A. Pai, Roger Piqué-Regi, Francesca Luca · 2017 · PLoS Genetics
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    Hai Fang, Liye Chen, Julian Charles Knight · 2019 · The Lancet Rheumatology
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    Giulietta Maria Riboldi, Ricardo A. Vialle, Elisa Navarro, Evan Udine, Kátia de Paiva Lopes, Jack Humphrey, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo et al. · 2022 · Molecular Neurodegeneration
44. Genetic insights into immune mechanisms of Alzheimer’s and Parkinson’s disease
    Alexi Nott, Inge R. Holtman · 2023 · Frontiers in Immunology
45. Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation
    Heather M. Snyder, Tim A. Ahles, Stuart K. Calderwood, María C. Carrillo, Honglei Chen, Chung-Chou H. Chang, Suzanne Craft, Philip L. De Jager, Jane Ann Driver, Howard M. Fillit et al. · 2016 · Alzheimer s & Dementia
46. Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information
    Sebastian Guelfi, Karishma D’Sa, Juan Antonio Botía, Jana Vandrovcová, Regina Hertfelder Reynolds, David Zhang, Daniah Trabzuni, Leonardo Collado‐Torres, Andrew Thomason, Pedro Quijada Leyton et al. · 2020 · Nature Communications
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    Ray-Jones, Helen, Duffus, Kate, McGovern, Amanda, Martin, Paul, Shi, Chenfu, Hankinson, Jenny, Gough, Oliver, Yarwood, Annie, Morris, Andrew P., Adamson, Antony et al. · 2020 · BMC Biology
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    Patrycja Maszka, Magdalena Kwaśniak-Butowska, Dominik Cysewski, Jarosław W. Sławek, Ryszard Tomasz Smolenski, Marta Tomczyk · 2023 · Metabolites
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    Tobias Hegelmaier, Alexander Duscha, Christiane Desel, Sabrina Fuchs, Michal Shapira, Sivan Amidror, Qihao Shan, Gabriele I. Stangl, Frank Hirche, Stefan Kempa et al. · 2025 · Scientific Reports
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    Gloriia Novikova, Shea J. Andrews, Alan Edward Renton, Edoardo M. Marcora · 2021 · Molecular Neurodegeneration
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    Laura P. Hughes, Marília Pereira, Deborah A. Hammond, John B. Kwok, Glenda Margaret Halliday, Simon J.G. Lewis, Nicolas L. Dzamko · 2021 · Journal of Parkinson s Disease
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    Xu, Lu, Li, Lei, Pan, Cai‐Long, Song, Jing‐Jing, Zhang, Chen‐Yang, Wu, Xiang‐Hui, Hu, Fan, Liu, Xue, Zhang, Zhiren, Zhang, Zhi‐Yuan · 2022 · The EMBO Journal
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    Arjan Malekzadeh, Cyra E Leurs, Wessel N. van Wieringen, Martijn D. Steenwijk, Menno Michiel Schoonheim, Michael Amann, Yvonne Naegelin, Jens Kühle, Joep Killestein, Charlotte Elisabeth Teunissen · 2019 · Annals of Clinical and Translational Neurology
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    Alexander M. Kulminski, Leonardo Shu, Yury Loika, Liang He, Alireza Nazarian, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Anatoliy I. Yashin, Irina V. Culminskaya · 2020 · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
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    Silva Kasela, François Aguet, Sarah Kim-Hellmuth, Brielin C. Brown, Daniel C. Nachun, Russell P. Tracy, Peter Durda, Yongmei Liu, Kent D. Taylor, W. Craig Johnson et al. · 2024 · The American Journal of Human Genetics
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    Elisabeth Yaneske, Claudio Angione · 2018 · BMC Bioinformatics
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    Xianwen Ye, Haixia Zhang, Qian Li, Hongmin Ren, Xinfang Xu, Xiang-Ri Li · 2023 · International Journal of Molecular Sciences
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    Satesh Ramdhani, Elisa Navarro, Evan Udine, Anastasia G. Efthymiou, Brian M. Schilder, Madison Parks, Alison Goate, Towfique Raj · 2020 · PLoS Genetics
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    Lu Xu, Cailong Pan, Xiang‐Hui Wu, Jingjing Song, Ping Meng, Lei Li, Li Wang, Zhiren Zhang, Zhi-Yuan Zhang · 2021 · Brain Behavior and Immunity
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    Maria Sobczyk, Tom G. Richardson, Verena Zuber, Josine L. Min, GoDMC, Tom R. Gaunt, Lavinia Paternoster · 2021 · Journal of Investigative Dermatology
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    Lili A. Milani, Liis Leitsalu, Andres Metspalu · 2014 · Journal of Internal Medicine
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    Michael Hecker, Nina Boxberger, Nicole Illner, Brit Fitzner, Ina Schröder, Alexander Winkelmann, Aleš Dudešek, Stefanie Meister, Dirk Koczan, Peter Lorenz et al. · 2019 · PLoS Genetics
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    Verena M. Link, David Gosselin, Christopher K. Glass · 2015 · Cold Spring Harbor Symposia on Quantitative Biology
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    Wei Song, Zi-ming Zhou, Lele Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yongmei Zhang · 2025 · Cell Death and Disease
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    Tze Hau Lam, Meixin Shen, Matthew Zirui Tay, Ee Chee Ren · 2017 · G3 Genes Genomes Genetics
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    Lorenzo Bonaguro, Maren Köhne, Lisa Schmidleithner, Jonas Schulte-Schrepping, Stefanie Warnat‐Herresthal, Arik Horne, Paul Kern, Patrick S. Günther, Rob ter Horst, Martin Jaeger et al. · 2020 · Nature Immunology
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    Azusa Kobayashi, Ayaka Ito, Ibuki Shirakawa, Atsushi Tamura, Susumu Tomono, Hideo Shindou, Per Niklas Hedde, Miyako Tanaka, Naotake Tsuboi, Takuji Ishimoto et al. · 2021 · Frontiers in Immunology
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    Roman Kosoy, John F. Fullard, Jaroslav M. Bendl, Steven P. Kleopoulos, Zhiping Shao, Stathis Argyriou, Deepika Dayal Mathur, Konstantina Psychogyiou, Periklis Malakates, James M. Vicari et al. · 2025 · Nature Neuroscience
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    Adithya Gopinath, Andria L. Doty, Phillip M. Mackie, Basil Hashimi, Madison L. Francis, Leila Saadatpour, Kaustuv Saha, Gerry Shaw, Adolfo Ramirez‐Zamora, Michael S. Okun et al. · 2019 · Journal of Immunological Methods
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    Damien C. Croteau‐Chonka, Angela J. Rogers, Towfique Raj, Michael J. McGeachie, Weiliang Qiu, John P. Ziniti, Benjamin J. Stubbs, Liming Liang, Fernando D. Martínez, Robert C. Strunk et al. · 2015 · PLoS ONE
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    Min Xu, Qianjin Liu, Rui Bi, Yu Li, Hongli Li, Wei-Bo Kang, Zhongjiang Yan, Quanzhen Zheng, Chunli Sun, Maosen Ye et al. · 2023 · Biological Psychiatry
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    Julio E. Molineros, Bhupinder Singh, Chikashi Terao, Yukinori Okada, Jakub Kaplan, Barbara McDaniel, Shuji Akizuki, Celi Sun, Carol F. Webb, Loren L. Looger et al. · 2019 · Frontiers in Immunology
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    Shuquan Rao, Mahdi Ghani, Zhiyun Guo, Yuetiva K. Deming, Kesheng Wang, Rebecca Sims, Canquan Mao, Yao Yao, Carlos Cruchaga, Dietrich A. Stephan et al. · 2018 · Neurobiology of Aging
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    Anthony J. Griswold, Sathesh Kumar Sivasankaran, Derek Van Booven, Olivia K. Gardner, Farid Rajabli, Patrice L. Whitehead, Kara L. Hamilton‐Nelson, Larry Deon Adams, Aja M. Scott, Natalia K. Hofmann et al. · 2020 · Journal of Alzheimer s Disease
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    Arianne C. Richard, James E. Peters, James Christopher Lee, Golnaz Vahedi, Alejandro A. Schäffer, Richard M. Siegel, Paul Lyons, Kenneth G. C. Smith · 2016 · Genome Medicine
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    Zuo-Teng Wang, Chen‐Chen Tan, Lan Tan, Jin‐Tai Yu · 2018 · Neuroscience & Biobehavioral Reviews
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    Michael Pudjihartono, Jo Kate Perry, Cristin Gregor Print, Justin Martin O'Sullivan, William S. Schierding · 2022 · Clinical Epigenetics
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    James Hrastelj, Robert Andrews, Samantha Loveless, Joanne Morgan, Stefan Mark Bishop, Nicholas J. Bray, Nigel M. Williams, Neil P. Robertson · 2021 · Brain Communications
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