GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment

Millisecond-timescale, genetically targeted optical control of neural activity

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How Inhibition Shapes Cortical Activity

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Lateral habenula as a source of negative reward signals in dopamine neurons

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Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

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Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

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The habenula: from stress evasion to value-based decision-making

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Afferent connections of the habenular nuclei in the rat. A horseradish peroxidase study, with a note on the fiber‐of‐passage problem

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Synaptic potentiation onto habenula neurons in the learned helplessness model of depression

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Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient

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Citalopram — Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity

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Chronic Social Defeat Stress Induces Pathway-Specific Adaptations at Lateral Habenula Neuronal Outputs

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Excitatory somatostatin interneurons in the dentate gyrus drive a widespread seizure network in cortical dysplasia

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Widespread co-release of glutamate and GABA throughout the mouse brain

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Regulation of fear extinction versus other affective behaviors by discrete cortical scaffolding complexes associated with NR2B and PKA signaling

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Co-transmitting neurons in the lateral septal nucleus exhibit features of neurotransmitter switching

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Corticotropin Releasing Factor (CRF) Coexpression in GABAergic, Glutamatergic, and GABA/Glutamatergic Subpopulations in the Central Extended Amygdala and Ventral Pallidum of Young Male Primates

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Multi-level variations of lateral habenula in depression: A comprehensive review of current evidence

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UBR‐1 ubiquitin ligase regulates the balance between GABAergic and glutamatergic signaling

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Plasma metabolomic profiles associated with chronic distress in women

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The Neuromeric/Prosomeric Model in Teleost Fish Neurobiology

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Somatostatin-Expressing Interneurons Co-Release GABA and Glutamate onto Different Postsynaptic Targets in the StriatumPreprint

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Effects of early life stress and subsequent re-exposure to stress on neuronal activity in the lateral habenula

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Habenular functional connections are associated with depression state and modulated by ketamine

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Corticosterone Signaling and a Lateral Habenula–Ventral Tegmental Area Circuit Modulate Compulsive Self-Injurious Behavior in a Rat Model

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Functional Implications of Neurotransmitter Segregation

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Circadian Influences on the Habenula and Their Potential Contribution to Neuropsychiatric Disorders

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Muscarinic Acetylcholine M 2 Receptors Regulate Lateral Habenula Neuron Activity and Control Cocaine Seeking Behavior

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Blockade of pre-synaptic and post-synaptic GABAB receptors in the lateral habenula produces different effects on anxiety-like behaviors in 6-hydroxydopamine hemiparkinsonian rats

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Critical test of the assumption that the hypothalamic entopeduncular nucleus of rodents is homologous with the primate internal pallidum

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Glutamatergic fast-spiking parvalbumin neurons in the lateral hypothalamus: Electrophysiological properties to behavior

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Actions of Neuropeptide Y on Synaptic Transmission in the Lateral Habenula

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Acute L-DOPA administration reverses changes in firing pattern and low frequency oscillatory activity in the entopeduncular nucleus from long term L-DOPA treated 6-OHDA-lesioned rats

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NDNF is selectively expressed by neocortical, but not habenular neurogliaform cells

Webster, J. F., Vroman, R., Beerens, S., Sakata, S., & Wozny, C. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15237 · Cited by 11

The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants

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Co-localization of different neurotransmitter transporters on synaptic vesicles is sparse except of VGLUT1 and ZnT3Preprint

Upmanyu, N., Jin, J., von der Emde, H., Ganzella, M., Bösche, L., Malviya, V. N., Zhuleku, E., Politi, A. Z., Ninov, M., Silbern, I., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.30.449903 · Cited by 11

Analytical approaches to examine gamma-aminobutyric acid and glutamate vesicular co-packaging

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Exercise therapy for chronic pain: How does exercise change the limbic brain function?

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Causal association between plasma metabolites and diverse autoimmune diseases: a two-sample bidirectional mendelian randomization study

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Abnormal functional connectivity in the habenula is associated with subjective hyperarousal state in chronic insomnia disorder

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Expression of GAD2 in excitatory neurons projecting from the ventrolateral periaqueductal gray to the locus coeruleus

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Differential Subcellular Distribution and Release Dynamics of Cotransmitted Cholinergic and GABAergic Synaptic Inputs Modify Dopaminergic Neuronal Excitability

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GABAergic innervation of the ciliary ganglion in macaque monkeys – A light and electron microscopic study

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Various transgenic mouse lines to study proopiomelanocortin cells in the brain stem label disparate populations of GABAergic and glutamatergic neurons

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Advances in Molecular and Circuitry Mechanisms of Depressive Disorder—A Focus on Lateral Habenula

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Raman spectroscopy of γ-aminobutyric acid under high pressure

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The Emerging Role of LHb CaMKII in the Comorbidity of Depressive and Alcohol Use Disorders

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Alterations of neurotransmitters and related metabolites in the habenula from CUMS-susceptible and -resilient rats

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Development of the GABAergic and glutamatergic neurons of the lateral hypothalamus

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Activation of AMPA Receptors in the Lateral Habenula Produces Anxiolytic Effects in a Rat Model of Parkinson’s Disease

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Single-Nucleus Transcriptional Profiling of GAD2-Positive Neurons From Mouse Lateral Habenula Reveals Distinct Expression of Neurotransmission- and Depression-Related Genes

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Lateral habenula deep brain stimulation alleviates depression-like behaviors and reverses the oscillatory pattern in the nucleus accumbens in an animal model of depression

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Prediction of Fruit Free Amino Acids by Foliar Nutrient Diagnosis in Longan (Dimocarpus longan Lour.)

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The Lateral Habenula Is Necessary for Maternal Behavior in the Naturally Parturient Primiparous Mouse Dam

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Mild stress accumulation limits GABAergic synaptic plasticity in the lateral habenula

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GABAB receptors constrain glutamate presynaptic release and postsynaptic actions in substantia gelatinosa of rat spinal cord

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Excessive ER-mitochondria coupling: A DRP1-driven mechanism underlying mitochondrial dysfunction and impaired autophagy in stress-induced depression-like behavior in mice

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Targeting Endocannabinoid Signaling in the Lateral Habenula as an Intervention to Prevent Mental Illnesses Following Early Life Stress: A Perspective

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Role of Neuroglia in the Habenular Connection Hub of the Dorsal Diencephalic Conduction System

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Alteration of LHb Function Induces Enduring Anxiety, Preventing the Proper Exploration of a Novel Environment

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Effect of dynamic interaction of estrous cycle and stress on synaptic transmission and neuronal excitability in the lateral habenula

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A decision-space model explains context-specific decision-making

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Nanoscopic distribution of VAChT and VGLUT3 in striatal cholinergic varicosities suggests colocalization and segregation of the two transporters in synaptic vesicles

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Behavioral and neuro-functional consequences of eliminating the KCNQ3 GABA binding site in mice

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Counselors’ Neuroscience Conceptualizations of Depression

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The Mouse Hypothalamus

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Total Recall: Lateral Habenula and Psychedelics in the Study of Depression and Comorbid Brain Disorders

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Bidirectional mechanism of comorbidity of depression and insomnia based on synaptic plasticity.

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Crash course in pallidus–habenula signaling

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Inactivation of endopeduncular nucleus impaired fear conditioning and hippocampal synaptic plasticity in rats

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The Molecular Basis of Neural Memory. Part 6: Chemical Coding of Logical and Emotive Modes

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Lateral habenula M2 muscarinic receptor control of neuronal activity and cocaine seeking behaviorPreprint

Wolfe, C. I. C., Hwang, E.-K., Zapata, A. G., Hoffman, A. F., & Lupica, C. R. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.24.453572 · Cited by 4

Transcriptional complexity in the insect central complex: single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblastsPreprint

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Transcriptional complexity in the insect central complex: single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblastsPreprint

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The lateral habenula as a master regulator of innate and learned social behaviors

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Effects of γ-Aminobutyric Acid and Glutamate Signalings from Primary Sensory Neurons to Gate the Spinal Transmission of Mechanical Pain in Mice

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Dopaminergic hypersensitivity of the opioid-responsive striatal–entopeduncular pathway in a rodent model of restless legs syndrome

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Distinct release properties of glutamate/GABA co-transmission serve as a frequency-dependent filtering of supramammillary inputs

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Activation of 5-HT1 receptor in lateral habenula impaired contextual fear memory and hippocampal LTP in rat

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Pallidal circuits drive addiction behavior

Campbell, R. R., & Lobo, M. K. (2023) · Trends in Neurosciences · doi:10.1016/j.tins.2023.10.001 · Cited by 3

Modeling the Role of Contour Integration in Visual Inference

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Involvement of a central amygdaloid nucleus–lateral habenular nucleus pathway in the processing of formalin-induced pain

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Optogenetics: Illuminating the Neural Circuits of Depression

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Tonic activity in lateral habenula neurons promotes disengagement from reward-seeking behaviorPreprint

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Sst+ GPi output neurons provide direct feedback to key nodes of the basal ganglia and drive behavioral flexibilityPreprint

Weglage, M., Ährlund-Richter, S., Contestabile, A., Skara, V., Fuzik, J., Santos, I., Lazaridis, I., & Meletis, K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.16.484460 · Cited by 4

Prevalent co-release of glutamate and GABA throughout the mouse brainPreprint

Ceballos, C. C., Ma, L., Qin, M., & Zhong, H. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.27.587069 · Cited by 3

Synaptic sign switching mediates online dopamine updatesPreprint

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Mitogen-activated protein kinase dependent presynaptic potentiation in the lateral habenula mediates depressive-like behaviors in rats

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A novel brainstem nucleus orchestrating reward and aversion

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Why stay lonely packaged in a synaptic vesicle when you can be in good company? A GABA-glutamate gathering

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Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleusPreprint

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PSA-NCAM in the posterodorsal medial amygdala is necessary for the pubertal emergence of attraction to female odors in male hamsters

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Glutamatergic Dysfunction of Lateral Habenula Promotes Depression

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Habenular Synapses and Nicotine

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