Cited by 1,325Advanced Electron Microscopy Techniques and ApplicationsEnzyme Structure and FunctionProtein Structure and Dynamics

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The Resolution Revolution

Kühlbrandt, Werner·2014·Science

DOI 10.1126/science.1251652

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Abstract

Advances in detector technology and image processing are yielding high-resolution electron cryo-microscopy structures of biomolecules. [Also see Report by Amunts et al. ]

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Authors: Kühlbrandt, W.
Affiliations: Max Planck Institute of Biophysics (DE)
Corresponding author: Kühlbrandt, Werner
ORCID: Kühlbrandt, Werner
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2014-03-28
Volume: 343
Issue: 6178
Pages: 1443-1444
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.1251652
OpenAlex: W2051925784
Cited by: 1,325
References: 10
Citations by year: 2026: 120 · 2025: 117 · 2024: 130 · 2023: 110 · 2022: 135 · 2021: 142 · 2020: 121 · 2019: 142 · 2018: 109 · 2017: 73 · 2016: 60 · 2015: 51 · 2014: 15
Type: journal article
Language: en
Open access: closed
Locations: Science (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Structural Biology › Advanced Electron Microscopy Techniques and Applications
Life Sciences › Biochemistry, Genetics and Molecular Biology › Structural Biology › Enzyme Structure and Function
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
Keywords: cryo-electron microscopy, high-resolution structure determination, biomolecular structure, detector technology, image processing
MeSH terms: Mitochondria, Saccharomyces cerevisiae, Ribosome Subunits, Large, Eukaryotic

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