The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix
Open accessAbstract
Push me, pull you, that's the way to move: Primary cells, derived directly from human tissue, exhibit different behaviors in shape and signaling within three-dimensional (3D) or 2D spaces. When the pressure within the cell increases, cells display limb-like bumps, which they use to move through their 3D environment. Petrie et al. now show that when the complex of actin and myosin contracts, it controls the pressure within cells and therefore the shape of those protruding structures (see the Perspective by DeSimone and Horwitz). The authors measured internal pressures in migrating mammalian cells. In the 3D matrix, those cells have higher pressure that differs between the front and back of the cell, which creates a piston effect. Science , this issue p. 1062 ; see also p. 1002
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Cited by
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Denais, C. M., Gilbert, R. M., Isermann, P., McGregor, A. L., te Lindert, M., Weigelin, B., Davidson, P. M., Friedl, P., Wolf, K., & Lammerding, J. (2016) · Science · doi:10.1126/science.aad7297 · Cited by 1,318
Cancer cell motility: lessons from migration in confined spaces
Paul, C. D., Mistriotis, P., & Konstantopoulos, K. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2016.123 · Cited by 648
Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets
Di, X., Gao, X., Peng, L., Ai, J., Jin, X., Qi, S., Li, H., Wang, K., & Luo, D. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01501-9 · Cited by 622
Mechanoreciprocity in cell migration
van Helvert, S., Storm, C., & Friedl, P. (2018) · Nature Cell Biology · doi:10.1038/s41556-017-0012-0 · Cited by 587
Case, L. B., & Waterman, C. M. (2015) · Nature Cell Biology · doi:10.1038/ncb3191 · Cited by 520
Metadata
- Authors
- Petrie, R. J., Koo, H., & Yamada, K. M.
- Venue
- Science
- Published
- 2014-08-29
- Volume
- 345
- Issue
- 6200
- Pages
- 1062-1065
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2168243900
- Cited by
- 366
- References
- 22
- FWCI
- 15.38
- Type
- journal article
- Language
- en
- Open access
- green
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