What if Minkowski Had Been Ageusic? An Alternative Angle on Diabetes

Pathogenesis of NIDDM. A balanced overview.

DeFronzo, R. A., Bonadonna, R. C., & Ferrannini, E. (1992) · Diabetes Care · doi:10.2337/diacare.15.3.318 · Cited by 2,085

Regulation of hepatic fatty acid oxidation and ketone body production

McGarry, J. D., & Foster, D. W. (1980) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.49.070180.002143 · Cited by 1,460

Influence of Dietary Fat Composition on Development of Insulin Resistance in Rats: Relationship to Muscle Triglyceride and ω-3 Fatty Acids in Muscle Phospholipid

Storlien, L. H., Jenkins, A. B., Chisholm, D. J., Pascoe, W. S., Khouri, S., & Kraegen, E. W. (1991) · Diabetes · doi:10.2337/diab.40.2.280 · Cited by 967

Measurement of Plasma Glucose, Free Fatty Acid, Lactate, and Insulin for 24 h in Patients With NIDDM

Reaven, G. M., Hollenbeck, C., Jeng, C.-Y., Wu, M. S., & Chen, Y.-D. I. (1988) · Diabetes · doi:10.2337/diab.37.8.1020 · Cited by 753

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

Vionnet, N., Stoffel, M., Takeda, J., Yasuda, K., Bell, G. I., Zouali, H., Lesage, S., Velho, G., Iris, F., Passa, P., et al. (1992) · Nature · doi:10.1038/356721a0 · Cited by 605

Regulation of ketogenesis and the renaissance of carnitine palmitoyltransferase

McGarry, J., Woeltje, K. F., Kuwajima, M., & Foster, D. W. (1989) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610050305 · Cited by 359

Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus

Vaag, A., Henriksen, J. E., & Beck-Nielsen, H. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115656 · Cited by 299

Diabetic Hyperglycemia: Link to Impaired Glucose Transport in Pancreatic β Cells

Unger, R. H. (1991) · Science · doi:10.1126/science.2006409 · Cited by 263

Mechanisms decreasing glucose oxidation in diabetes and starvation: Role of lipid fuels and hormones

Randle, P. J., Kerbey, A. L., & Espinal, J. (1988) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610040702 · Cited by 241

New Antidiabetic Drugs

Bailey, C. J., & Flatt, P. R. (1990) · Medical Entomology and Zoology · Cited by 214

Differential effects of acute hypertriglyceridemia on insulin action and insulin receptor autophosphorylation

Gumbiner, B., Mucha, J. F., Lindström, J., Rekhi, I., & Livingston, J. N. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.3.e424 · Cited by 23

Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity

GUSTAFSON, L. A., Kuipers, F., Wiegman, C., Sauerwein, H. P., Romijn, J. A., & Meijer, A. J. (2002) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00212-x · Cited by 22

NO-1886 inhibits size of adipocytes, suppresses plasma levels of tumor necrosis factor-α and free fatty acids, improves glucose metabolism in high-fat/high-sucrose-fed miniature pigs

Yin, W., Liao, D., Wang, Z., Xi, S., Tsutsumi, K., Koike, T., Fan, J., Yi, G., Zhang, Q., Yuan, Z., et al. (2003) · Pharmacological Research · doi:10.1016/j.phrs.2003.09.008 · Cited by 22

Physiological Indirect Effect Modeling of the Antilipolytic Effects of Adenosine A1-Receptor Agonists

van Schaick, E. A., de Greef, H. J. M. M., IJzerman, A. P., & Danhof, M. (1997) · Journal of Pharmacokinetics and Biopharmaceutics · doi:10.1023/a:1025777700413 · Cited by 22

Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation

Sun, X., Haas, M. E., Miao, J., Mehta, A. J., Graham, M. J., Crooke, R. M., de Barros, J.-P. P., Wang, J., Aikawa, M., Masson, D., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.668269 · Cited by 23

Rapid Nitration of Adipocyte Phosphoenolpyruvate Carboxykinase by Leptin Reduces Glyceroneogenesis and Induces Fatty Acid Release

Jaubert, A., Penot, G., Niang, F., Durant, S., & Forest, C. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040650 · Cited by 21

Phosphodiesterase 3B gene expression is enhanced in the liver but reduced in the adipose tissue of obese insulin resistant db/db mouse

Tang, Y., Osawa, H., Onuma, H., Nishimiya, T., Ochi, M., Sugita, A., & Makino, H. (2001) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(01)00271-6 · Cited by 21

Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse

Tang, Y., Osawa, H., Onuma, H., Hasegawa, M., Nishimiya, T., Ochi, M., & Makino, H. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1450093 · Cited by 21

Differential impact of acute and chronic lipotoxicity on gene expression in INS-1 cells

Xiao, J., Gregersen, S., Pedersen, S. B., & Hermansen, K. (2002) · Metabolism · doi:10.1053/meta.2002.29977 · Cited by 20

Pathogenesis of obesity and diabetes mellitus: insights provided by indirect calorimetry in humans

Perseghin, G. (2001) · Acta Diabetologica · doi:10.1007/s005920170023 · Cited by 21

Transgenic studies of fatty acid oxidation gene expression in nonobese diabetic mice

Kurtz, D. M., Tian, L., Gower, B. A., Nagy, T. R., Pinkert, C. A., & Wood, P. A. (2000) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32368-3 · Cited by 20

Inflammation and Insulin Resistance: An Old Story with New Ideas

Kim, J. K. (2010) · Korean Diabetes Journal · doi:10.4093/kdj.2010.34.3.137 · Cited by 19

Pitfalls in using BMI as a selection criterion for bariatric surgery

Livingston, E. H. (2012) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e328357f0b8 · Cited by 19

Resveratrol metabolites ameliorate insulin resistance in HepG2 hepatocytes by modulating IRS-1/AMPK

Teng, W., Yin, W., Zhao, L., Ma, C., Huang, J., & Ren, F. (2018) · RSC Advances · doi:10.1039/c8ra05092a · Cited by 19

In vitro targeted screening and molecular docking of stilbene, quinones, and flavonoid on 3T3-L1 pre-adipocytes for anti-adipogenic actions

Bedi, O., Aggarwal, S., Trehanpati, N., Ramakrishna, G., Grewal, A. S., & Krishan, P. (2020) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-020-01919-w · Cited by 19

Lipocalin-2 in Fructose-Induced Fatty Liver Disease

Lambertz, J., Berger, T., Mak, T. W., van Helden, J., & Weiskirchen, R. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00964 · Cited by 19

Increased susceptibility to peroxidation of VLDL from non-insulin-dependent diabetic patients: A possible correlation with fatty acid composition

Rabini, R. A., Tesei, M., Galeazzi, T., Dousset, N., Ferretti, G., & Mazzanti, L. (1999) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006994931023 · Cited by 19

Role of Protein Kinase C Isoenzymes in Fatty Acid Stimulation of Insulin Secretion

Littman, E. D., Pitchumoni, S., Garfinkel, M. R., & Opara, E. C. (2000) · Pancreas · doi:10.1097/00006676-200004000-00006 · Cited by 19

Aspects of Novel Sites of Regulation of the Insulin Stimulus-Secretion Coupling in Normal and Diabetic Pancreatic Islets

Sjöholm, Å. (1998) · Endocrine · doi:10.1385/endo:9:1:1 · Cited by 19

Hypercholesterolemia-induced ocular disorder: Ameliorating role of phytotherapy

El‐Sayyad, H. I., El‐Mansi, A. A., & Bakr, E. H. (2015) · Nutrition · doi:10.1016/j.nut.2015.05.013 · Cited by 18

Determinants of the Changes in Glycemic Control with Exercise Training in Type 2 Diabetes: A Randomized Trial

Johannsen, N. M., Sparks, L. M., Zhang, Z., Earnest, C. P., Smith, S. R., Church, T. S., & Ravussin, É. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062973 · Cited by 18

Appetite Control: Does leptin lighten the problem of obesity?

McGarry, J. (1995) · Current Biology · doi:10.1016/s0960-9822(95)00264-8 · Cited by 20

Evaluation of treadmill exercise effect on muscular lipid profiles of diabetic fatty rats by nanoflow liquid chromatography–tandem mass spectrometry

Lee, J. C., Kim, I. Y., Son, Y., Byeon, S. K., Yoon, D. H., Son, J. S., Song, H. S., Song, W. J., Seong, J. K., & Moon, M. H. (2016) · Scientific Reports · doi:10.1038/srep29617 · Cited by 17

Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways

Hu, Y., Semova, I., Sun, X., Kang, H. M., Chahar, S., Hollenberg, A. N., Masson, D., Hirschey, M. D., Miao, J., & Biddinger, S. B. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.782557 · Cited by 17

Piperazine Oxadiazole Inhibitors of Acetyl-CoA Carboxylase

Bourbeau, M. P., Siegmund, A., Allen, J. G., Shu, H., Fotsch, C. H., Bartberger, M. D., Kim, K., Komorowski, R., Graham, M., Busby, J., et al. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm401601s · Cited by 17

Fatty acids and insulin secretion

Amery, C. M., & Nattrass, M. (2000) · Diabetes Obesity and Metabolism · doi:10.1046/j.1463-1326.2000.00059.x · Cited by 18

Postprandial whole-body glycolysis is similar in insulin-resistant and insulin-sensitive non-diabetic humans

Galgani, J. E., & Ravussin, É. (2011) · Diabetologia · doi:10.1007/s00125-011-2413-0 · Cited by 16

Hyperinsulinaemia: does it tip the balance toward intrahepatic fat accumulation?

Hodson, L., & Karpe, F. (2019) · Endocrine Connections · doi:10.1530/ec-19-0350 · Cited by 16

Effects of Benfluorex on Fatty Acid and Glucose Metabolism in Isolated Rat Hepatocytes

Kohl, C., Ravel, D., Girard, J. R., & Pégorier, J. P. (2002) · Diabetes · doi:10.2337/diabetes.51.8.2363 · Cited by 16

Cucumis melo ssp. Agrestis var. AgrestisAmeliorates High Fat Diet Induced Dyslipidemia in Syrian Golden Hamsters and Inhibits Adipogenesis in 3T3-L1 Adipocytes

Gaikwad, A. N., Shankar, K., Singh, S. K., Kumar, D., Varshney, S., Gupta, A., Rajan, S., Srivastava, A., Beg, M., Srivastava, A. K., et al. (2015) · Pharmacognosy Magazine · doi:10.4103/0973-1296.172945 · Cited by 16

Albert Renold Memorial Lecture: Molecular Background of Nutritionally Induced Insulin Resistance Leadingto Type 2 Diabetes – From Animal Models to Humans

Shafrir, E. (2001) · Journal of Diabetes Research · doi:10.1155/edr.2001.299 · Cited by 16

Differentiation-Induced Insulin Secretion from Nonendocrine Cells with Engineered Human Proinsulin cDNA

Yamasaki, K., Sasaki, T., Nemoto, M., Eto, Y., & Tajima, N. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1698 · Cited by 16

Changes in the Expression of Hypothalamic Lipid Sensing Genes in Rat Model of Intrauterine Growth Retardation (IUGR)

Puglianiello, A., Germani, D., Antignani, S., Tomba, G., & Cianfarani, S. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3180332d4e · Cited by 15

Factors Affecting Insulin-Regulated Hepatic Gene Expression

Guan, H.-P., & Chen, G. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-800101-1.00006-5 · Cited by 15

Síndrome de resistencia a la insulina. estudio y manejo

Fernando Carrasco, N., Galgani, F. J. E., & Reyes, J. M. (2013) · Revista Médica Clínica Las Condes · doi:10.1016/s0716-8640(13)70230-x · Cited by 20

Metabolic manifestations of polycystic ovary syndrome in nonobese adolescents: retinol-binding protein 4 and ectopic fat deposition

Sopher, A. B., Gerken, A. T., Blaner, W. S., Root, J. M., McMahon, D. J., & Oberfield, S. E. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.01.111 · Cited by 15

Lipoprotein Profiles in Class III Obese Caucasian and African American Women with Nonalcoholic Fatty Liver Disease

Whitlock, A. E. G., Kasim, N. R., Tamboli, R. A., González, R. S., Antoun, J., Eckert, E. A., Marks–Shulman, P. A., Dunn, J. P., Wattacheril, J. J., Wallen, T. E., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0142676 · Cited by 15

Exercise, Nutrition, and Supplements in the Muscle Carnitine Palmitoyl-Transferase II Deficiency: New Theoretical Bases for Potential Applications

Negro, M., Cerullo, G., Parimbelli, M., Ravazzani, A., Feletti, F., Berardinelli, A. L., Cena, H., & D’Antona, G. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.704290 · Cited by 15

The Epidemic of Type 2 Diabetes Mellitus: Its Links to Obesity, Insulin Resistance, and Lipotoxicity

Cusi, K. J. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-260-1_1 · Cited by 15

Effect of dietary vegetable oil consumption on blood glucose levels, lipid profile and weight in diabetic mice: an experimental case—control study

Ngala, R. A., Ampong, I., Sakyi, S. A., & Anto, E. O. (2016) · BMC Nutrition · doi:10.1186/s40795-016-0053-y · Cited by 16

Role of the Adipocyte in Metabolism and Endocrine Function

Ravussin, É., & Smith, S. R. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00036-6 · Cited by 16

Non-Alcoholic Fatty Liver Disease: Translating Disease Mechanisms into Therapeutics Using Animal Models

Basha, A., May, S. C., Anderson, R. M., Samala, N. R., & Mirmira, R. G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24129996 · Cited by 14

Islet hormones at the intersection of glucose and amino acid metabolism

White, P. J., Albrechtsen, N. J. W., & Campbell, J. E. (2025) · Nature Reviews Endocrinology · doi:10.1038/s41574-025-01100-4 · Cited by 15

In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis—Technical Aspects and Model Interpretation

Deja, S., Kucejová, B., Fu, X., Browning, J. D., Young, J. D., & Burgess, S. C. (2021) · Metabolites · doi:10.3390/metabo11050279 · Cited by 14

Glycéronéogenèse et PEPCK-C

Cadoudal, T., Fouque, F., Benelli, C., & Forest, C. D. (2008) · médecine/sciences · doi:10.1051/medsci/2008244407 · Cited by 14

Reduction of Plasma Leptin Concentrations by Arginine but Not Lipid Infusion in Humans

Stingl, H., Raffesberg, W., Nowotny, P., Waldhäusl, W. K., & Roden, M. (2002) · Obesity Research · doi:10.1038/oby.2002.151 · Cited by 14

Amelioration of insulin resistance but not hyperinsulinemia in obese mice overexpressing GLUT4 selectively in skeletal muscle

Tsao, T., Katz, E. B., Pommer, D., & Charron, M. J. (2000) · Metabolism · doi:10.1016/s0026-0495(00)90220-8 · Cited by 14

Impaired Glucose Tolerance

Costa, N., Conget, I., & Gomis, R. (2002) · Treatments in Endocrinology · doi:10.2165/00024677-200201040-00001 · Cited by 14

Pathophysiology of Canine Diabetes

Hoenig, M. E. (1995) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/s0195-5616(95)50052-x · Cited by 14

Expression of precursor and mature carnitine palmitoyltransferase II in Escherichia coli and in vitro: differential behaviour of rat and human isoforms

Brown, N. F., Sen, A., Soltis, D. A., Jones, B., Foster, D. W., & McGarry, J. (1993) · Biochemical Journal · doi:10.1042/bj2940079 · Cited by 14

Unsaturated fatty acids repress the expression of ATP-binding cassette transporter A1 in HepG2 and FHs 74 Int cells

Ku, C. S., Rasmussen, H. E., Park, Y., Jesch, E. D., & Lee, J. (2011) · Nutrition Research · doi:10.1016/j.nutres.2011.03.007 · Cited by 13

Liver Proteome in Diabetes Type 1 Rat Model: Insulin-Dependent and -Independent Changes

Braga, C. P., Boone, C. H. T., Grove, R. A., Adamcova, D., Fernandes, A. A. H., Adamec, J., & Padilha, P. D. M. (2016) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2016.0135 · Cited by 13

Association of the promoter polymorphism −232C/G of the phosphoenolpyruvate carboxykinase gene (PCK1) with Type 2 diabetes mellitus

Gouni‐Berthold, I., Giannakidou, E., Faust, M., Berthold, H. K., & Krone, W. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01819.x · Cited by 13

The potential beneficial effect of leptin on an experimental model of hyperlipidemia, induced by chronic ethanol treatment

Vairappan, B., & Nalini, N. (2003) · Clinica Chimica Acta · doi:10.1016/j.cccn.2003.07.004 · Cited by 13

The effect of insulin on net lipid oxidation predicts worsening of insulin resistance and development of type 2 diabetes mellitus

Koška, J., Ortega, E., Bogardus, C., Krakoff, J. A., & Bunt, J. C. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00662.2006 · Cited by 13

Targeted inhibition of PPAR α ameliorates CLA ‐induced hypercholesterolemia via hepatic cholesterol biosynthesis reprogramming

Liu, H., Hu, P., Li, Y., Sun, M., Qu, H., Zong, Q., Gu, H., Chen, X., Bao, W., & Cai, D. (2022) · Liver International · doi:10.1111/liv.15199 · Cited by 12

Egr1 plays a major role in the transcriptional response of white adipocytes to insulin and environmental cues

Meriin, A. B., Zaarur, N., Roy, D., & Kandror, K. V. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1003030 · Cited by 13

Cardiomyopathy and angiogenesis defects of Wistar rat fetuses of diabetic and hypercholesterolemic mothers

El‐Sayyad, H. I., Al-Haggar, M. S., El-Ghawet, H. A., & Bakr, I. H. (2012) · Nutrition · doi:10.1016/j.nut.2011.12.013 · Cited by 12

Postprandial lipemia induces pancreatic α cell dysfunction characteristic of type 2 diabetes: studies in healthy subjects, mouse pancreatic islets, and cultured pancreatic α cells

Niederwanger, A., Ciardi, C., Tatarczyk, T., Khan, M. I., Hermann, M., Mittermair, C., Al‐Zoairy, R., Salzmann, K., & Pedrini, M. T. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.092023 · Cited by 12

CrossTalk proposal: Intramuscular lipid accumulation causes insulin resistance

Goodpaster, B. H. (2020) · The Journal of Physiology · doi:10.1113/jp278219 · Cited by 12

Improved metabolic control by depletion of Liver X Receptors in mice

Schuster, G. U., Johansson, L., Kietz, S., Stulnig, T. M., Parini, P., & Gustafsson, J.-Α. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.07.044 · Cited by 12

A new drug target for treatment of dyslipidaemia associated with type 2 diabetes and the metabolic syndrome?

Naoumova, R. P., & Betteridge, D. J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09315-7 · Cited by 12

The antilipolytic action of bis(α-furancarboxylato)oxovanadium(IV) in adipocytes

Gao, L., Niu, Y., Liu, W., Xie, M., Liu, X., Chen, Z., & Li, L. (2007) · Clinica Chimica Acta · doi:10.1016/j.cca.2007.10.014 · Cited by 12

Expression of subcutaneous adipose tissue phosphoenolpyruvate carboxykinase correlates with body mass index in nondiabetic women

Chang, T., Lee, W., Chang, H., Lee, K., & Chuang, L. (2008) · Metabolism · doi:10.1016/j.metabol.2007.10.012 · Cited by 12

Regulation of pdx-1 Gene Expression

Gerrish, K., Samaras, S. E., Cissell, M. A., Wright, C. V. E., & Stein, R. W. (2001) · Endocrine updates · doi:10.1007/978-1-4615-1669-9_16 · Cited by 12

Effects of PPARα on cardiac glucose metabolism: a transcriptional equivalent of the glucose-fatty acid cycle?

Finck, B. N. (2006) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.4.2.161 · Cited by 12

Dehydroepiandrosterone Alters Zucker Rat Soleus and Cardiac Muscle Lipid Profiles

Abadie, J. M., Malcom, G. T., Porter, J. R., & Svec, F. (2001) · Experimental Biology and Medicine · doi:10.1177/153537020222600811 · Cited by 12

Effect of a broad recombination zone with a triple-emitting layer on the efficiency of blue phosphorescent organic light-emitting diodes

Lee, S. J., Koo, J., Lee, H. W., Lee, S. E., Yang, H.-J., Yoon, S. S., Park, J., & Kim, Y. K. (2014) · Electronic Materials Letters · doi:10.1007/s13391-014-4132-4 · Cited by 11

Metabolic Effects of Selective Deletion of Group VIA Phospholipase A2 from Macrophages or Pancreatic Islet Beta-Cells

TURK, J. W., Song, H., Wohltmann, M., Frankfater, C., Lei, X., & Ramanadham, S. (2020) · Biomolecules · doi:10.3390/biom10101455 · Cited by 11

Fatty acid synthase inhibition ameliorates diabetes induced liver injury in rodent experimental model

Bedi, O., Srivastava, N., Parsad, D., & Krishan, P. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2021.174078 · Cited by 11

Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect

Becattini, B., Molinaro, A., Henricsson, M., Borén, J., & Solinas, G. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114132 · Cited by 11

Amelioration of diabetic dyslipidemia by macrocyclic binuclear oxovanadium complex on streptozotocin induced diabetic rats

Ramachandran, B., & Subramanian, S. P. (2005) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-005-6988-y · Cited by 11

Study on the Correlation between the Nutrient Intakes and Clinical Indices of Type 2 Diabetes Patients

Kwon, J.-Y., & Chung, H.-Y. (2013) · The Korean Journal of Food And Nutrition · doi:10.9799/ksfan.2013.26.4.909 · Cited by 10

Recent Advances in Acetyl-CoA Carboxylase Inhibitors

Bourbeau, M. P., Allen, J. G., & Gu, W. (2010) · Annual reports in medicinal chemistry · doi:10.1016/s0065-7743(10)45006-x · Cited by 10

Sensitivity of young rats to nicotine exposure: Physiological and biochemical parameters

Jósê, A. S., Franciscato, C., Sônego, F., Figueiró, M., Thiesen, F. V., García, S. C., & Pereira, M. E. (2008) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2008.03.010 · Cited by 10

Classification and Diagnosis of Diabetes Mellitus

Dinneen, S. F., & Rizza, R. A. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00039-3 · Cited by 10

Exendin-4 Promotes Survival of Mouse Pancreaticβ-Cell Line in Lipotoxic Conditions, through the Extracellular Signal-Related Kinase 1/2 Pathway

Gu, J., Wei, Q., Zheng, H., Meng, X., Zhang, J., & Wang, D. (2016) · Journal of Diabetes Research · doi:10.1155/2016/5294025 · Cited by 9

Classical cardiovascular risk factors according to fasting plasma glucose levels

Martínez‐Hervás, S., Romero, P., Hevilla, E. B., Real, J. T., Priego, A., Martin-Moreno, J. M., Carmena, R., & Ascaso, J. F. (2007) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2007.09.005 · Cited by 9

Intracellular Depletion of Insulin by Oleate Is Due to an Inhibited Synthesis and Not to an Increased Secretion

Bollheimer, L. C., Kestler, T., Michel, J., Buettner, R., Schölmerich, J., & Palitzsch, K. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5604 · Cited by 9

The hypertriglyceridemia is associated with isolated impaired glucose tolerance in subjects without insulin resistance

Simental‐Mendía, L. E., Rodríguez‐Morán, M., & Guerrero‐Romero, F. (2014) · Endocrine Research · doi:10.3109/07435800.2014.934963 · Cited by 9

SREBP-1 und Fettleber

Müller‐Wieland, D., Knebel, B., Haas, J., & Kotzka, J. (2012) · Herz · doi:10.1007/s00059-012-3608-y · Cited by 10

A new piece in the diabetes puzzle

Rossetti, L., & Goldberg, I. J. (2002) · Nature Medicine · doi:10.1038/nm0202-112 · Cited by 9

Interactions between effects of adrenalectomy and diet on insulin secretion in fa/fa Zucker rats

Kibenge, M. T., & Chan, C. B. (2001) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y00-106 · Cited by 9

β‐cell GLUT‐2 loss and non‐insulin‐dependent diabetes mellitus: Current status of the hypothesis

Milburn, J. L., Ohneda, M., Johnson, J. H., & Unger, R. H. (1993) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610090306 · Cited by 9

Antischizophrenic activity independent of dopamine D2 blockade

Kalkman, H. O. (2002) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.6.5.571 · Cited by 9

Heart disease in diabetes—resist the beginnings

Taegtmeyer, H., & Razeghi, P. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.11.003 · Cited by 9

Insulin Gene Transcription: Factors Involved in Cell Type–Specific and Glucose‐Regulated Expression in Islet β Cells are Also Essential During Pancreatic Development

Stein, R. W. (2001) · Comprehensive physiology · doi:10.1002/cphy.cp070202 · Cited by 9

Commentary on SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect fatty acid translocation

Pownall, H. J. (2020) · Journal of Lipid Research · doi:10.1194/jlr.c120000745 · Cited by 9

Das metabolische Syndrom: „common soil“ für Diabetes und Atherosklerose

Hanefeld, M., Metzler, W., Köhler, C., & Schäper, F. (2006) · Herz · doi:10.1007/s00059-006-2798-6 · Cited by 8

Acute Treatment With XMetA Activates Hepatic Insulin Receptors and Lowers Blood Glucose in Normal Mice

Bedinger, D., Kieffer, D. A., Goldfine, I. D., Roell, M. K., & Adams, S. H. (2015) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25168 · Cited by 8

Hypoxia aggravates non-alcoholic fatty liver disease in presence of high fat choline deficient diet: A pilot study

Sarkar, S., Bhattacharya, S., Alam, M. J., Yadav, R., & Banerjee, S. K. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118404 · Cited by 8

8.4 Metabolomics: Concepts and Potential Neuroscience Applications

Kristal, B. S., Kaddurah-Daouk, R. F., Beal, M. F., & Matson, W. R. (2007) · Springer eBooks · doi:10.1007/978-0-387-30411-3_33 · Cited by 8

Advanced Glycation Endproducts and Their Receptor: Do They Play a Role in Diabetic Cardiomyopathy?

Arai, M. (2002) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2002.2097 · Cited by 8

Utility of metformin as an adjunct to hydroxycitrate/carnitine for reducing body fat in diabetics

McCarty, M. F. (1998) · Medical Hypotheses · doi:10.1016/s0306-9877(98)90035-4 · Cited by 8

Coffee pulp improves glucose and lipid metabolism disorder in high-fat diet-induced diabetic mice

Zhu, S., Wang, C., & Meng, Z. (2024) · Metabolism Open · doi:10.1016/j.metop.2024.100303 · Cited by 7

Glyceroneogenesis, the pathway that almost wasn't

Hanson, R. W., Ballard, F. J., & Reshef, L. (2006) · Biochemistry and Molecular Biology Education · doi:10.1002/bmb.2006.494034052637 · Cited by 7

Beta‐cell injury in Ncb5or‐null mice is exacerbated by consumption of a high‐fat diet

Guo, Y., Xu, M., Deng, B., Frontera, J. R., Kover, K. L., Aires, D., Ding, H., Carlson, S. E., TURK, J. W., Wang, W., et al. (2011) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201100309 · Cited by 7

Revisiting cardiovascular risk reduction in type 2 diabetes and dyslipidemia

Lim, P., & Bleich, D. (2022) · International Journal of Cardiology Cardiovascular Risk and Prevention · doi:10.1016/j.ijcrp.2022.200141 · Cited by 7

Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice

Fatehi‐Hassanabad, Z., & Chan, C. B. (2007) · Nutrition & Metabolism · doi:10.1186/1743-7075-4-6 · Cited by 7

The Metabolic Syndrome

Ruderman, N. B., & Shulman, G. I. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00044-7 · Cited by 7

New Insights into Lipid Metabolism in Non-insulin-dependent Diabetes Mellitus

Taskinen, M., Lahdenperä, S., & Syvänne, M. (1996) · Annals of Medicine · doi:10.3109/07853899608999090 · Cited by 48

Metabolische Störungen bei Diabetes mellitus, ihre Diagnose und Therapie

Waldhäusl, W. K. (1984) · Klinische Anästhesiologie und Intensvtherapie · doi:10.1007/978-3-642-70125-2_2

Disordered lipid metabolism and the pathogenesis of insulin resistance.

Savage, D. B., Petersen, K. F., & Shulman, G. I. (2007) · Physiological Reviews · doi:10.1152/physrev.00024.2006 · Cited by 1,107

The Central Role of Lipid Metabolism Disorders in Diabetes Mellitus: Mechanisms, Clinical Manifestations, and Emerging Therapeutic Strategies

Yang, Q., Liu, X., Zhang, T., Zhao, X., & 肖小河 (2026) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s591764 · Cited by 6

Lipid metabolism and insulin sensitivity

Wu, X. (2024) · Theoretical and Natural Science · doi:10.54254/2753-8818/46/20240400 · Cited by 1